The Lancet is publishing its first Series on transgender health. 1 Winter S Diamond M Green J et al. Transgender people: health at the margins of society. Lancet. 2016; (published online June 17.)http://dx.doi.org/10.1016/S0140-6736(16)00683-8 Google Scholar , 2 Wylie K Knudson G Khan SI Bonierbale M Wayanyusakul S Baral S Serving transgender people: clinical care considerations and service delivery models in transgender health. Lancet. 2016; (published online June 17.)http://dx.doi.org/10.1016/S0140-6736(16)00682-6 Google Scholar , 3 Reisner SL Poteat T Keatley J et al. Global health burden and needs of transgender populations: a review. Lancet. 2016; (published online June 17.)http://dx.doi.org/10.1016/S0140-6736(16)00684-X Google Scholar Transgender people live in all countries, but their acceptance by communities and freedom to live with their chosen gender identity or expression varies according to culture and society. This Series, led by Sam Winter of Curtin University and Kevin Wylie of the University of Sheffield, is the result of a committed effort by experts and members of the transgender community—some of whom contributed to a piece about community voices for the Series. 4 Reisner S Keatley J Baral S et al. Transgender community voices: a participatory population perspective. Lancet. 2016; (published online June 17.)http://dx.doi.org/10.1016/S0140-6736(16)30709-7 Google Scholar Synergies in health and human rights: a call to action to improve transgender health“Transphobia is a health issue.”J V R Prasada Rao, UN Secretary-General's Special Envoy for AIDS in Asia and the Pacific1 Full-Text PDF Transgender community voices: a participatory population perspectiveUnderstanding the global health burden and needs of transgender communities necessitates meaningful engagement and involvement of transgender people. Against the backdrop of widespread social and economic exclusion facing people of diverse gender identities and experiences, community empowerment is essential for clinical services, public health programmes, and human rights efforts that seek to design and implement effective services and population-level interventions to improve the health and wellbeing of transgender people. Full-Text PDF Transgender people: health at the margins of societyIn this paper we examine the social and legal conditions in which many transgender people (often called trans people) live, and the medical perspectives that frame the provision of health care for transgender people across much of the world. Modern research shows much higher numbers of transgender people than were apparent in earlier clinic-based studies, as well as biological factors associated with gender incongruence. We examine research showing that many transgender people live on the margins of society, facing stigma, discrimination, exclusion, violence, and poor health. Full-Text PDF Serving transgender people: clinical care considerations and service delivery models in transgender healthThe World Professional Association for Transgender Health (WPATH) standards of care for transsexual, transgender, and gender non-conforming people (version 7) represent international normative standards for clinical care for these populations. Standards for optimal individual clinical care are consistent around the world, although the implementation of services for transgender populations will depend on health system infrastructure and sociocultural contexts. Some clinical services for transgender people, including gender-affirming surgery, are best delivered in the context of more specialised facilities; however, the majority of health-care needs can be delivered by a primary care practitioner. Full-Text PDF Global health burden and needs of transgender populations: a reviewTransgender people are a diverse population affected by a range of negative health indicators across high-income, middle-income, and low-income settings. Studies consistently document a high prevalence of adverse health outcomes in this population, including HIV and other sexually transmitted infections, mental health distress, and substance use and abuse. However, many other health areas remain understudied, population-based representative samples and longitudinal studies are few, and routine surveillance efforts for transgender population health are scarce. Full-Text PDF Gender and health: between nomenclatures and continuumsAddressing transgender health in a Lancet Series and in The Lancet Psychiatry1 constitutes a milestone for health professionals and social scientists. I draw conclusions from some of these papers on how we consider health, disease, and gender, and on the purpose of the nomenclatures we have developed and use. Full-Text PDF