Lajpat Rai Research Articles

Histopathological and Immunohistochemical Studies of a Spontaneous Case of Pulmonary Adenomatosis in an Adult Ram: A Case Report

Aim: The present study aimed to describe histopathological findings and immunohistochemical expression of proliferating cell nuclear antigen (PCNA) in a spontaneous case of pulmonary adenomatosis in an adult ram. Case Presentation: A carcass of an adult ram was presented for necropsy in the Post-mortem Hall of the Department of Veterinary Pathology, College of Veterinary Sciences of the Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar with a history of respiratory distress. A detailed necropsy was performed. The tracheal mucosa showed mild congestion. The lungs were pale and firm in consistency. On histopathological examination, nasal turbinate and trachea both showed the vascular changes along with mild infiltration of mononuclear cells. The sections of lungs revealed pulmonary adenocarcinoma characterized by the presence of cuboidal to low columnar epithelial cells forming acinar or papillary-like structures in the parenchyma and surrounded by the normal alveoli. Areas of necrosis along with infiltration of mononuclear cells were also evident. An Immunohistochemical study of the lung sections revealed mild to moderate immunopositive reactivity for the PCNA in the nuclei of neoplastic cells of adenocarcinoma. It indicated the proliferative activity of neoplastic cells. Conclusion: Based on histopathological examination, the present case was diagnosed as pulmonary adenomatosis. PCNA expression indicated the presence of actively proliferating neoplastic cells.

Bibliometric analysis of management practices in US corn (1990–2020)

AbstractBibliometric analysis explores large volume of scientific data, revealing trends and insights in a specific research field. Consistently, a bibliometric analysis of 30 years (1990–2020) was performed within the US corn (Zea mays L.) production using the Scopus database and VOSviewer. Search query was performed within the article title, abstract, and keywords indicative of management practices in corn. Exclusion criterion based on subject area and journals generated a total of 7468 publications. The data analysis revealed contributions from 7327 authors and 47 organizations documented in 69 journals. The top five organizations leading the investigation were United States Department of Agriculture – Agricultural Research Service, Iowa State University, University of Nebraska, University of Illinois, and Purdue University. The most prolific authors were Dr. Rattan Lal (Ohio State University, Columbus, OH), Dr. Douglas L. Karlen (USDA‐ARS, Ames, IA), Dr. Kenneth G. Cassman (University of Nebraska, Lincoln, NE), Dr. Lajpat Rai Ahuja (USDA‐ARS, Ft. Collins, CO), and Dr. John Walsh Doran (USDA‐ARS, Lincoln, NE). Journals with most publications were Agronomy Journal; Soil Science Society of America Journal; Soil and Tillage Research; Crop Science; and Agriculture, Ecosystems & Environment. Furthermore, author keywords differed from queried keywords, and no‐till, nitrogen, cover crop, soybean, irrigation, phosphorus, conservation tillage, yield, and water quality were most prominent. Moreover, there was an evident shift in keywords and an observed trend between 1998 and 2020. Overall, these findings allow researchers to explore network maps via the hyperlinks present in papers, identifying research gaps and advancing original studies to bridge gaps in the literature.

Association of Diabetic Peripheral Neuropathy with Micronutrients.

Diabetes mellitus (DM) is a common metabolic disorder that has been defined by hyperglycemia. Diabetic patients usually have high levels of oxidative stress. Mitochondrial dysfunction and inflammation of blood vessels are associated with a greater need for micronutrients in diabetic patients. These micronutrients may have an association with the complications in diabetics. The purpose of this study was to show the association of diabetic peripheral neuropathy (DPN) with levels of micronutrients such as copper (Cu), zinc (Zn), magnesium (Mg), and vitamin B12 (Vit B12). This cross-sectional study was conducted in the Department of Medicine, Lala Lajpat Rai Memorial Medical College, Meerut. A total of 130 randomly selected cases of confirmed type-2 diabetic patients were included in this study. DPN cases were identified using the Michigan neuropathy screening instrument. Out of 130 diabetic patients, 28 patients were found to have diabetic neuropathy. The level of various micronutrients was assessed and correlated with the development of DPN. The association of DPN with Zn (p-value of 0.02) and Vit B12 (p-value of 0.008) was found to be significant, whereas Cu (p-value of 0.57) and Mg (p-value of 0.24) were found to be insignificant.

Retrospective study on occurrence of bovine gastrointestinal parasitic infections in different regions of Haryana

The production and reproduction of livestock is hampered by the presence of gastrointestinal (GI) parasitic infections. The effect of parasites ranges from anorexia, loss of body condition, anaemia, diarrhoea, protein losing enteropathy and loss of body condition apart from aforementioned direct and indirect effects on the animals leads to huge economic losses to livestock owners. In the present study, a total of 1669 faecal samples from cattle (n=550) and buffaloes (n=1119) with the history of diarrhoea or digestive disturbances were processed for presence of parasitic infections at different disease investigation laboratories (Ambala, Bhiwani, Mahendragarh and Rohtak) of Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana from July 2021 to June 2022. All the faecal samples were processed by floatation and sedimentation methods for detection of parasitic eggs and the results revealed that 29.6% cattle and 34.7% buffaloes were positive for GI parasites. Buxtonella sulcata (17.7%), Amphistomes (5.2%), and Strongyles (6.9%) were the major parasites observed in cattle and buffaloes. The occurrence of parasitic infection was significantly higher (P<0.05) in Rohtak followed by Bhiwani, Ambala and the least in Mahendragarh district of Haryana. However, no significant difference (P>0.05) between the cattle and buffaloes of geographical regions was observed. Further, analysis of month, season and age influences on prevalence of GI parasites were found to have no significant impact (P>0.05). Overall, this study helps to assess the parasitic load within the study region and helps to further devise control strategies against the parasites of bovines.

Estimation of the seminal parameters of rooster and its association with fertility traits in synthetic dam line.

The objective of the present study was to assess the seminal parameters of rooster and its association with fertility traits (%), viz., hatchability of the fertile egg set (HFES), hatchability of the total egg set (HTES), and fertility (FERT). The data records pertained to traits of interest were obtained from various registers maintained at Poultry farm, of the Department of Animal Genetics and Breeding, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar (India). The relationship between seminal and fertility characteristics was investigated using regression analysis and correlation. Moreover, the efficacy of seminal characteristics to distinguish between roosters with low and high fertility traits was evaluated using linear discriminant analysis (LDA). The findings showed that reproductive traits and seminal characteristics were significantly (P < 0.05) correlated. The LDA showed that the seminal parameters can effectively separate the roosters into those with high and poor reproductive features. It was revealed from LDA that seminal features showed higher classification accuracy for FERT (80.77%). Hatchability is dependent on eggs that have been artificially incubated; hence, these crucial traits are comparatively weaker for HTES (65.38%) and HFES (67.31%). Cross-validation of the seminal parameter LDA corroborated the aforementioned and related conclusions. It is suggested that the studied LDA function may be utilised to choose genotypes with improved reproductive traits based on seminal variables.

Maternal Near-Miss and Maternal Mortality in a Tertiary Care Center of Western Uttar Pradesh: A Retrospective Study.

Maternal mortality is an important indicator to assess the quality of services provided by the health care system. However, maternal near-misses as well as maternal mortality are also indicators of how well the health care system serves pregnant women. To improve our healthcare system in terms of investigative capacity, infrastructure, and personnel, a near-miss registry can provide important information on gaps in pregnancy facilities. This will help us to identify the requirements for referral facility improvements and the need for various health awareness programs. We, therefore, designed this study to analyze the various near-miss events in mothers and compare them with maternal mortality. Present study was conducted in the Department of Obstetrics and Gynecology, Lala Lajpat Rai Memorial (L.L.R.M.) Medical College associated with Sardar Vallabh Bhai Patel (S.V.B.P.) Hospital Meerut, Uttar Pradesh (UP), India for a period of one year and data were collected retrospectively from January 2022 to January 2023. All patients with life-threatening conditions such as excessive bleeding during pregnancy, hypertensive disorders of pregnancy (HDP), and septicemia that occurred during pregnancy or childbirth or within 42 days of termination of pregnancy and required ICU admissions, were included in the study. The total number of deliveries during the study period was 4,360 with 4,333 live births (LB). The total number of eligible cases was 79, out of which 52 were identified as maternal near misses and 27 were maternal mortality. Various maternal mortality and near-miss indices were analysed and statistical analysis was done using the SPSS version 21 (IBM Corp., Armonk, NY, USA). Our hospital's maternal mortality ratio (MMR)was 623/1lakh (0.623%), which is higher than the probability due to the deficiency of appropriate medical services in the nearby areas of western UP. The number of maternal near misses per 1000 LB (maternal near-miss ratio [MNMR]) was 12/1000 LB and the severe maternal outcome rate (SMOR) was 18/1000 LB (1.82%). In our study, hemorrhage and hypertensive disorder in pregnancy were the leading cause of morbidity and mortality followed by sepsis and severe anemia. Among organ dysfunction cardiac illness followed by respiratory dysfunction was the leading cause of morbidity and mortality. It is clear that there is a high burden of maternal near-miss in developing countries. There should be the establishment of well-equipped referral units at the periphery with trained manpower. The establishment of obstetrical high-dependence units (HDUs), rapid availability of blood and blood products, training of staff, and availability of multidisciplinary teams can minimize maternal mortality and morbidity.

Physico-chemical, sensory, and microbiological quality of raw chicken meat: an exploratory study in the Hisar city of Haryana, India.

A survey was conducted in Hisar, located in Haryana, India, to assess the quality of raw chicken meat. To ensure comprehensive coverage, healthy broiler chickens were obtained from various meat retail outlets in Hisar city, encompassing the majority of such establishments. Additionally, a sample of control chickens was obtained from the Livestock Farm, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar, Haryana, India. The raw chicken meat was grouped into two categories, breast cut and thigh cut. The breast muscles, which include pectoralis major and pectoralis minor, and the thigh muscles, which include the abductor muscles, were chosen as the samples for proximate analysis, which included physico-chemical, sensory, and microbiological analyses of raw chicken meat. The analysis of the raw meat in the laboratory revealed inconsistent variations between the control and retail samples in terms of parameters, such as proximate composition, pH, the water-holding capacity (WHC), thiobarbituric acid (TBA), instrumental color analysis, and sensory evaluation. The moisture content of the control breast sample was significantly higher (p < 0.05) than that of the samples from shops 2, 3, and 5. However, it was statistically similar to that of the samples from shops 1, 4, and 6. The total plate and psychrotrophic counts of the control thigh sample were significantly lower than those of the samples from shops 3, 4, 5, and 6. Among the thigh pH values, the samples from shops 1, 2, 5, and 6 had significantly higher pH values than the control sample. The variations in the various parameters were multifactorial and established the superiority of birds slaughtered under laboratory conditions and grown in university farms compared to the raw chicken meat available in retail outlets in Hisar city.

The interpretation of platelet indices (platelet count, mean platelet volume, and platelet distribution width) as additional diagnostic tool for neonatal sepsis

Objective: This study aims to determine whether platelet indices (PI) (platelet count, mean platelet volume [MPV], and platelet distribution width [PDW]) are an additional diagnostic tool for neonatal sepsis (NS). Materials and Methods: This observational and cross-sectional study was done between April 2020 and April 2021 at the neonatal intensive care unit (NICU) of Lala Lajpat Rai Memorial Medical College Meerut, Uttar Pradesh, India. Neonates with sepsis-like apnea, abdominal distension, refusal of feed, increased pre-feed aspirates, tachycardia, hypothermia, chest retractions, lethargy, and grunting; neonates with sepsis screen positive and/or culture positive; and neonates born to mothers with sepsis risk factors were included in the study. After proper aseptic condition, the venous blood sample was collected in ethylenediaminetetraacetic acid (EDTA) vial and sent to the pathology laboratory for further analysis of complete blood count (CBC) absolute neutrophil count (ANC), total leukocyte count (TLC), C-reactive protein, platelet frequency, MPV, and PDW. The data were analyzed using SPSS v26.0. Results: A total of 60 babies were enrolled, of which 30 neonates with sepsis were categorized as group “cases” (n = 30), and those (n = 30) neonates without sepsis were classified as group “controls.” Platelet count (low), MPV, and PDW (high) were found to be significant predictors of NS (P &lt; 0.05). Conclusion: This study reports that the frequently employed PI (MPV, platelet count, and PDW) are significant predictors of the incidence of NS in NICU settings. There was no significant change in PI in prematurity and low birth weight neonates. These platelet indicators may be used as markers to detect the incidence of NS in low-resource settings.

The Hinduism and Hindu Nationalism of Lala Lajpat Rai

Lala Lajpat Rai was a prominent figure of the Arya Samaj, the influential nineteenth-century Hindu socio-religious reform movement. He is also seen as having sown the seeds of Hindu nationalism in the first decade of the twentieth century. Exploring Lajpat Rai’s thought between the 1880s and 1915, this article traces how felt imperatives of Hindu nation-building impelled him to regularly re-define Hinduism. These first prompted Rai to articulate a ‘thin’ Hinduism, defined less in terms of an insistence on a complex set of beliefs and more in broad, simple terms. They then induced him to culturalise Hinduism and make a distinction between ‘Hinduism’ and ‘Hindu culture’. The article ends by comparing the Hinduism and Hindu nationalism of Lajpat Rai and V.D. Savarkar, the chief ideologue of the Hindutva ideology, which is considered the main influence on India’s Hindu nationalist movement. It argues that while formulations of a thin and culturalised Hinduism enabled both men to articulate a ‘Hindu nationalism’, their nationalisms in fact remained qualitatively different. By scrutinizing intellectual trends and processes occurring in Rai’s thought, the article demonstrates that the modern ideology of Hindu nationalism impacted how Hindu religion was defined and re-defined and how such re-definitions can still produce distinct forms of Hindu nationalism.

Print Internationalism's Uneasy Adjacencies

Print Internationalism's Uneasy Adjacencies

COMPARING DIAGNOSTIC ACCURACY OF LUNG ULTRASOUND AGAINST CHEST XRAY FOR DETECTION OF PNEUMOTHORAX USING HRCT AS GOLD STANDARD.

Thoracic trauma is one of the most common locations of injury with an overall mortality rate of up to 10% making its recognition a priority in chest trauma assessment . Imaging plays a key role in guiding interventions and management in patients with chest trauma. Conventional imaging in the form of chest radiographs, ultrasounds, and computed tomography (CT) are usually performed in the emergency settings with CT scan as the gold standard for this diagnosis. But high radiation dose in CT scan has made chest X-ray a popular initial diagnostic tool in these cases. Apart from various disadvantages of chest X ray, many studies suggest its poor sensitivity and specicity in identifying intrathoracic injuries culminating in lower diagnostic yield. Recently, chest ultrasonography has emerged as a portable, inexpensive, safe, and fast alternative for radiography in detection of traumatic intrathoracic injuries. So, the present study was undertaken to compare the diagnostic accuracy of this newly surfaced chest ultrasonography and the conventional chest radiography in identifying traumatic intrathoracic injuries. Objective: To evaluate and compare the accuracy, sensitivity and specicity of chest ultrasound and chest x ray as a diagnostic tool in detection of pneumothorax, in trauma patients using CT thorax as gold standard. Study design: Descriptive study. Place and duration of study :Department of General Surgery, Lala Lajpat Rai Hospital, GSVM Medical College, Kanpur, UP, India, between December 2020 to October 2022. Methodology : In the present descriptive study, patients with traumatic intrathoracic injuries, who were referred to the emergency department between December 2020 to October 2022, were assessed. The patients underwent bedside chest ultrasound (USG), x ray and computed tomography (CT) scan examinations based on ATLS recommendations. Results : Eighty ve patients with mean age 41.13 ± 17.2 ( range 7-87 ) were taken (68.24 % males ).CT scan showed pneumothorax, in 94.12 %, cases Whereas chest ultrasonography in comparison to radiography detected pneumothorax in 69.41 % respectively. Comparison of sensitivity, specicity, positive predictive value and negative predictive value after taking CT thorax as gold standard gave accuracy of 76.27 % to USG thorax and 50.85 % to chest x ray (p =0.0005 )for detecting pneumothorax , Conclusions : The results of the present study showed that ultrasonography is preferable to radiography in the initial evaluation of patients with traumatic injuries to the thoracic cavity.

Sonographic Detection of Surgical Site Fluid Collections and Postoperative Maternal Morbidity Following Cesarean Section.

Surgical site infection (SSI) is one of the most commoncomplications after cesarean and causes much burden on the mother as well as the health care system. SSIs are defined as infections of a surgical site up to 30 days after surgery. Ultrasonography of the surgical site may be a helpful tool to detect its complication. With this background, the following study was planned to evaluate the clinical significance of sonographically detected fluid collections and post-operative maternal morbidity following cesarean section (CS) and identify risk factors associated with their formation. This prospective observational study was conducted at the Department of Obstetrics and Gynecology, Lala Lajpat Rai Memorial Medical College, Meerut. A total of 1000 women, who had undergone CS were included. Sonographic examination of the cesarean site was done on the 3rd or 4th postoperative day to look for any fluid collection in the parities or pelvis. All cases were followed on the 8th postoperative day and finally on the 30th postoperative day to look for any SSIs i.e. surgical wound problems like wound infection, induration, and discharge from a surgical wound, or even wound dehiscence and postoperative morbidity. Results: Out of the total cases (1000), abdominal wound fluid collection was noted in 490 (49%) women after CS. Thirty-two patients were lost to follow-up, so 458 patients were followed, of which collection was septated or loculated in 62 (13.6%) and diffused in 396 (86.5%). Out of 62 loculated and 396 diffused cases, 21 (33.87%) and 20 (5.05%) cases reported surgical site abdominal wound infection and needed resuturing, respectively and it was found to be highly significant (p<0.001). Post-operative fluid collections are common after CS. But it is the pattern of the fluid collection that determines post-operative wound infection and morbidity. Thus ultrasound of the cesarean site may be an important tool to detect surgical site wound complications earlier and to decrease postoperative morbidity.

Contribution of Haryana in Non-Cooperation Movement

In the presented research paper, the participation of the people of Haryana in the non-cooperation movement has been highlighted. The year 1920 holds a very important place in Indian history. Because on this day the public was hoping that the First World War would end and the British Government will definitely do some good work for them but Raoult Act, Jallianwala Bagh. Reports like the massacre, and martial law in Punjab dashed all the hopes of the public. Gandhiji returned all his titles to the British, and he decided to launch a movement against the British. When the non-cooperation movement started in 1920, how could Haryana escape its influence? On the appeal of Gandhiji, many leaders returned the titles given by the government. Lawyers stopped going to government courts. Students from colleges and school boycotted the institutions. Holi of foreign goods burned by in various districts of Haryana State like Rohtak, Gurgaon, Ambala, Hisar. Shriram Sharma, Muralidhar, Lala Lajpat Rai etc. leaders strongly opposed the government. In this way, within no time, the movement spread throughout Haryana reached its zenith but at the same time when on 5 February 1922 a place called Chora-Chori , when the violence broke out, Gandhiji was deeply shocked and he suspended the movement . Thus on 5 February 1922 in India as well as in Haryana region Non-cooperation movement ended.

Evolution of the COVID-19 Pandemic: An Analysis of the Brunt of the Second and Third Waves on Patients in Western Uttar Pradesh.

Background: The recent second wave and the latest third wave of coronavirus disease 2019 (COVID-19) in India caused havoc on health infrastructure. However, there is a scarcity of studies from India and abroad that compare the second and third waves of the COVID-19 pandemic. We aimed to assess the factors like age, sex, and death comparison among diagnostically proven COVID-19 patients of the Meerut district in both waves.Methodology: A total of 297554 samples during the second wave (1st March 2021 to 30th June 2021) and 240655 during the third wave (1st January 2022 to 30th April 2022) were tested for reverse transcription polymerase chain reaction (RT-PCR) in the Department of Microbiology, Lala Lajpat Rai Medical College, using The Indian Council of Medical Research (ICMR) approved RT-PCR testing kits. The data like age, sex, place, follow-ups, etc. were recorded and data were analyzed statistically.Results: The RT-PCR positivity of 8.24% for COVID-19 in the second wave while 5.66% of patients in the third wave have been reported. The proportion of positive cases in children ≤10 years in the second and third wave were quite similar i.e., 3.59% and 3.40% respectively, whereas the proportion of positive cases in adolescents (10-20 years) was significantly higher (12.96%) in the third wave in contrast to the second wave (10.15%), while age group (41-60 years) is significantly less (26.65%) in proportion during the third wave in comparison to the second wave (29.50%). The proportion of positivity in young males has significantly increased in the third wave as compared to the second wave. The mortality also decreased significantly by 1/3rd of the second wave.Conclusion: The third wave showed low overall positivity (5.66%) as compared to the second wave (8.24%), while the brunt on young children was comparable to the second wave which was assumed to be higher. The mortality and hospitalization also decreased significantly in the second wave. Regular surveillance and analysis should continue to combat this pandemic.

Clinical Diagnosis and Therapeutic Management of Trypanosoma theileri Infection Associated with Peritonitis in Crossbred Cow: A Rare Case Report

The present study reports a very rare case of Trypanosoma theileri like infection in the peritoneal fluid of a 6-year-old female Holstein Friesian (HF) cattle brought to Veterinary Clinical Complex, Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar. The aim of the clinical study was to report an unusual case of T. theileri-like infection associated with peritonitis and its therapeutic management. For confirmatory diagnosis, peritoneal fluid and blood sample was collected from animal for haemato-biochemical examination, buffy coat examination and detection of Trypanosoma antigen by monoclonal antibody-based latex agglutination test. Animal had history of anorexia, high fever, oedematous swelling on the abdominal area and decrease in milk yield since 1 week. Clinical examination revealed high fever, congested conjunctival mucus membrane and oedematous inflammatory swelling on the abdominal region. Haematological examination on Day 1 revealed relative neutrophilia and eosinophilia, whereas other parameters measured were on the lower side of normal range. Thin blood smear examination did not reveal any parasite on first attempt. However, after confirmation of Trypanosoma species in peritoneal fluid collected by FNAC, buffy coat examination of blood sample was also found positive for Trypanosoma species. On Day 2, haematological examination revealed neutrophilic leucocytosis, eosinophilia and anaemia. Blood sample was also found serologically positive for Trypanosoma antigen by monoclonal antibody based latex agglutination test. Biochemical examination revealed increased blood urea nitrogen (BUN), gamma glutamyl transferase (GGT) levels, hyperglycemia, hyperprotienemia and decreased levels of sodium and chloride ions. Animal was primarily treated with isometamidium chloride (Nyzom®) @ 0.5mg/kg body weight (IM, single dose) along with supportive therapy. Animal showed clinical recovery after 10days of treatment. Post-recovery, blood sample of the animal was re-examined for parasite and other blood parameters and it was found negative for presence of Trypanosoma infection along with restoration of haematological values. Hence, the present study concludes the confirmatory diagnosis and therapeutic use of isometamidium hydrochloride along with anti-inflammatory drugs to Trypanosoma infection.

Mortality prediction by prognostic scoring in Hepatitis C- associated or non- associated cirrhotic patients

Objectives: Hepatitis C virus (HCV) is a hepatotropic virus that is one of the most common causes of liver disease and a potential cause of substantial morbidity and mortality worldwide. There is a paucity of data on the etiological profile of cirrhosis with HCV association in western Uttar Pradesh. Methodology: The observational type of study was carried out from June 2021 to May 2022 on patients attending in Medicine department at Lala Lajpat Rai Memorable Medical College, Meerut in collaboration with the Microbiology Department at National Capital Region Institute of Medical Sciences, Meerut, Uttar Pradesh, India. We included 247 patients who were diagnosed with cirrhosis, informed consent was taken with a 5 ml blood sample collected from each patient. The sample was screened for the qualitative detection of HCV-specific antibodies using 3rd generation Enzyme-linked immunosorbent assay (ELISA) from all the participants and Scored by the MELD score system. Result: A total of 247 confirmed cirrhosis patient’s, 52 (21%), patients were positive with the association of HCV in the age group of 41-60 and the mean age was 50 years. The 31 (59.6%) were males, and 21 (40.3%) were females positive for HCV in the low-status family.

SOLID WASTES GENERATION AT VARIOUS ZONES OFUNIVERSITIES CAMPUS: CHARACTERISATION AND ITSMANAGEMENT APPROACHES

Effective management strategy is required for handling the large quantities of waste produced by various societies/ organizations and waste characterization is essential to prepare this management policy. In this study, solid wastes collected from the combined campus of Chaudhary Charan Singh Haryana Agriculture University (CCSHAU) and Lala Lajpat Rai University of Veterinary and Animal Science (LUVAS), Hisar was characterized through population estimation, field investigations and applying ASTM D5231-92 standard method. In the combined campus, the average quantity of solid waste generation was found to be 1047.1±214.4 kg/day. The whole campus was divided into five structural units and waste composition was determined, mixture unit waste comprised the highest fraction of food 62.13% and polythene 10.8%. The statistical estimation obtained a strong positive correlation of mixture unit waste with residential and markets waste contents, which was 0.995 and 0.997 at p&lt;0.01. The analysis of solid samples showed that the biodegradable part of solid waste may be a better source for composting while some content of non-biodegradable waste can be sold into the market for recycle or reuse purpose. On the basis of solid waste characterization, a set of recommendations were suggested to strengthen the waste management processes for institutions.

Immunological and Hemato-biochemical alterations in diarrhoeic buffaloes screened for Mycobacterium avium subspecies paratuberculosis infection using ‘indigenous ELISA kit’

Paratuberculosis (ParaTB) in ruminants, commonly known as Johne’s disease (JD)is caused by Mycobacterium avium subspecies paratuberculosis (MAP). Characteristic hallmark of JD is chronic inflammation of intestines. Similar infection of MAP in human population is called Crohn's disease (CD). In sub-tropical countries like India, domestic buffaloes are important source of milk and meat and vital for thenutritional security of human beings. Diarrhoea leading to weight loss and weakness invariably leads to reduced productivity, therefore huge financial losses to the livestock farmers. Evaluation of immuno-biochemical alterations and their management through appropriate therapeutic interventions would aid in preventing production losses caused by diarrhoea following MAP infection.Most of the studies were performed to understand immune-biochemical alterations in serum samples of cattle following experimental infections. But studies are limited in clinical cases of buffaloes suffering from diarrhoea and were suspected for MAP infection.We categorized diarrhoeic buffaloes brought at Veterinary Clinical Complex of Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, for therapeutic intervention; As MAP negatives / suspected, low positive, positive and strong positive based on indigenous ELISA kit results. We further compared immuno hemato-biochemical alterations in MAP negative/suspected low positive, positive and strong positive animals.Our major findings were; significant differences observed in creatinine, globulin, total leucocytic, neutrophils and in lymphocytes numbers. Decreasing trend in leucocytes was seen from suspected to strong positive animals, which indicated the progression of disease towards chronic paratuberculosis. However, differences were not observed in the Th1 cytokine levels.

Radiological features of dengue fever in cases and control

Background: Dengue (pronounced DENgee) fever is a painful, debilitating mosquito-borne disease caused by any one of four closely related dengue viruses. Aim of the study was to study radiological features of dengue fever in cases and control.Methods: Randomized, double blind, placebo controlled, parallel group study conducted among 100 seropositive dengue patients,18-60 years of age (fulfilling inclusion and exclusion criteria) at Lala Lajpat Rai hospital, Kanpur for December 2019 October 2021. Selected patients were subjected to history, examination, necessary investigations and then were managed according to national vector borne disease control programme (NVBDCP) guidelines. A total of 100 serology proven dengue patients were included and followed up. Two groups (fifty in each) were allocated by simple first and then systematic random sampling. Case group was given doxycycline and control group was given placebo.Results: USG findings commonly seen in both the cases and control group were hepatomegaly, splenomegaly, ascites right pleural effusion, thickened GB wall and edema. In both the groups, pleural effusion was the most common complication.Conclusions: Ultrasound examinations detected plasma leakage in multiple body compartments around time of defervescence. Presence of plasma leakage in form of ascites and pleural effusion was more in control group as compared to case group seems doxycycline decrease the plasma leakage. Pleural effusion is most common finding of plasma leakage.

A Hindu Champion of Pan-Islamism: Lajpat Rai and the Khilafat Movement

AbstractLala Lajpat Rai is increasingly viewed in historiography as a “Hindu nationalist” with a strong affinity with Savarkarite Hindutva. This article demonstrates that during the Khilafat movement, Lajpat Rai articulated a secular Indian nationalism that was sensitive to Muslim religiosity and Indian Muslims’ extraterritorial sympathies toward the caliphate and the Muslim world. Pigeonholing the entire thought of Lajpat Rai as “Hindu nationalism” obscures a historical-intellectual juncture when a Hindu political figure like him enthusiastically supported pan-Islamism as necessary for Indian nationalism. This article complicates scholarship that portrays Hindu responses to the Khilafat movement as consisting solely of fear and counter-consolidation. More importantly, by unveiling Rai's Khilafat-era nationalism, it uncovers the intellectual and political possibility of firmly holding a Hindu identity and articulating conceptions of Indian nationhood that are at ease with Islam and the wider Muslim world.