Sexual activity of population, especially young people, is multiply significant for the population's health status. The beginning of sexual intercourses is constantly moving toward the younger age. The aim of the paper is observing the sexual activity in Serbia's population according to gender, age, territory, place of living, level of education and material status. Accordingly, the Institute of Public Health of Serbia made a survey in the whole territory of Serbia in 2000 and 2006. The results have shown that the experience in the sexual intercourse prelude such as embrace and kissing is acquired at an early age: at age of 10 increasing until the age of 14; thereafter the line is decreasing. The 91% citizens have the sexual intercourses. The sexual intercourses with the same gender have 2, 4% citizens, whereas 7, 6% citizens have sexual relations with irregular partner. The first sexual experience is acquired at the age of 17. Those intercourses have 56.2% young people have such intercourses. The beginning of sexual life is rising with educational level and material status. The reason of beginning of sexual life is love and because most of the friends have already entered into, the physical attraction and just the time for it. The reason for non-beginning of sexual life is the opinion that it is too early for it and the lack of partner. Contraceptive drugs are used by 37, 7% women and 36, 9% exert unknown methods. Interrupted coitus, women's days barren, condoms and intrauterine spiral are most frequent methods of contraception. Neither contraceptive methods is used by 21, 4% citizens.