We Are a Nation of Lonely Molecules* Peter Drucker in Post Capitalist Society (1994) postulates that we are living through a period where, within a few short decades, society has rearranged its world view, basic values, social and political structures, arts, and key institutions. Medicine and healthcare are among those key institutions that have been rearranged. Profound advances have been made in biomedicine including magnificent work on human genome project. Laboratory testing and new imaging techniques seem to have substantially replaced traditionally lengthy history-- taking process and physical examination lamented by Brooke (1986) in his muscle medicine reference to interesting other things to do during history and physical examination. Gone with detailed history and physical examination is related human contact and touching. Evidence-based medicine has been demanded by elite science community who value over all else double-blinded, placebo-controlled, double-crossover prospective study with results decoded by persons different than those posing clinical hypothesis. Although many might not agree with high priority placed on such studies, academic and clinical pressure to comply ensures most reductionistic of clinical mind-sets. Medical holism and integrated medicine is simply too ill-defined, too large, and too multifactorial for evidence basers to get their hands around. Real scientists are encouraged to avoid such foolishness. Further, integrated medicine modality literature is unfortunately shallow even with later-day improvements at National Institutes of Health level. In meanwhile, consumers (including patients and potential patients) are actively involved in new computer age and have access to megatons of information. But how are consumers to know what is reliable, credible, and usable, and what is garbage? How does one resolve inevitable Tower of Babel of opinions? Edward Hallowell (1999) writes, ... patients have `toxic worry.' It stems from a lack of face-to-face contact in a business world where travel, voice mail, faxes, and email allow us to conduct business without ever being in same room as our colleagues and customers. Add to that confusing contradictory advice one can dial up on Net supplied both by well-intentioned and unscrupulous. The who-to-believe syndrome aggravates toxic worry. You cannot look Internet straight in eye. You cannot judge credibility of handshake, or genuine-ness of character providing information. Shorris (1994) opines, the global village predicted by seers of 1960s is being replaced by electronic cottages populated by isolated dreamers ... we are a nation of lonely molecules. Stephen Byrum, PH.D., in his Bowles Lecture at Memorial Hermann Healthcare System (2000), discussed axiologic disorders referring to disturbances in realm of ethics and spirituality. He identifies major symptoms: loneliness; inability to enjoy awesome-ness of beauties of nature, art, music, and life; and attitudes such as, I don't care anymore. Nobody cares. It doesn't matter. Nothing matters. This all adds up to axiopathy ... suffering. Suffering is a universal affliction different from signs and symptoms of disease in traditional Western sense. Investigation of suffering demands attention to mood and feeling. It requires a beyond-superficial relationship with patient to be comfortable asking and having answered necessary but often highly personal questions. Spirituality and suffering are hardly addressed in today's hurried ten-minute clinical visits, yet suffering accompanies disease in varied degrees in all or most illnesses, leaving a large gap in a patient's sense of fulfillment from a physician visit. Addressing these sufferers requires deeper levels of communication. When offered, treatment must include reestablishing attachments. …