The article examines measures to regulate the labor market of the Russian Federation under the conditions of sanctions. The labor market in the new conditions was influenced by a unique combination of diverse economic, political, and social factors. An important feature of the current labor market configuration is the uneven impact of the negative effects of sanctions pressure on various sectors of economy and, as a result, the strengthening of structural imbalances, labor shortages in some sectors and excess in others. Sanctions challenges for the Russian economy have necessitated the need for rapid and adequate support for labor market participants.The article considers legal, administrative and financial measures to support the labor market in new conditions. Measures aimed at stabilizing the labor market and employment are operational and comprehensive, constantly being supplemented as the situation develops. The measures introduced include both administrative and regulatory and financial instruments to support labor market participants, both employees and employers. Special attention is paid to the preservation of human resources in general, and in the field of information technology in particular, as well as the development of entrepreneurial potential of citizens of the Russian Federation. The author suggests maintaining the course of maintaining economic activity of labor market participants, primarily by easing regulatory restrictions and facilitating access to financial resources (subsidies, credit availability, government orders). When making decisions on measures to support the labor market, give preference to complex solutions with high multiplicative and synergistic effects in various areas of the economy and social sphere. In the short term, take measures to ensure supply in order to avoid shortages of goods, ensure price stability and maintain employment in the production and distribution sectors. In the medium term, the main focus should be on maintaining demand from the state, business and individuals (for example, expanding infrastructure projects, supporting housing construction, introducing food certificates for the poor, etc. comprehensive solutions). In the long term, to provide a foundation for the growth of high-tech jobs through the development of machine-tool and mechanical engineering, electronics manufacturing, and other high-tech industries. This growth can be achieved both through the import of technologies and through the support of their own developments. Broad and timely informing of employees and employers about the support measures taken is necessary.