Six Myxobolus species are described from Nile fish, five of which are new and one is redescribed: M. naffari Abdel Ghaffar et al., 1998 was recovered from the gills of Labeo niloticus and the mouth of Barbus bynni; M. caudatus sp. n. was observed in the tail fin of B. bynni; M. fahmii sp. n. occurred in the gills of B. bynni; M. imami sp. n. was found in the kidney of L. niloticus; M. intestinalis sp. n. was recorded from the intestine of B. bynni; and M. perforata sp. n. was found in the internal surface of the operculum of Hydrocynus forskalii. The histological effects of some of the Myxobolus infections present are described.