Laboratory Reports Research Articles

Assessing the cost and utilization of SMS printers by primary health care facilities: lessons learned from South Africa.

Historically, paper-based laboratory reports were delivered by couriers to health facilities resulting in post-analytical delays. As a result, short message service (SMS) printers were deployed to fill this gap, with the global data service platform (GDSP) being primarily used to facilitate deployment. In addition, these printers generate binary and quantitative information that can be used to assess utilization. The objective of this study was to determine the costs and utilization of the SMS printer program in South Africa. A cost analysis for 2020 was undertaken. We determined annual equivalent costs (AEC) for staffing, printers, fixed costs related to the national coordinator, consumables, travel costs, database support/hosting/dashboard development, printer repairs, and results transmission. The main outcome of interest was the cost per SMS printer result delivered. Data were extracted to assess utilization as follows: i) months active (based on internet protocol data); ii) signal; iii) battery strength. There were 4,450,116 results delivered to printers that were situated at 2232 primary health care facilities. An AEC of $687,727 was reported, with a cost per result delivered of $0.1618. The SMS printers contributed 73.52% to the total AEC. Overall, 90% of the printers were GDSP based, of which only 69.5% were determined to be active. The majority of active printers reported a signal strength of ≥60% and a battery strength of ≥6 volts. Although the SMS printer program has the potential to reduce post-analytical delays, pathology services should migrate to an end-to-end electronic interface to improve patient care.

Capture ELISA for KPC Detection in Gram-Negative Bacilli: Development and Standardisation.

The detection of KPC-type carbapenemases is necessary for guiding appropriate antibiotic therapy and the implementation of antimicrobial stewardship and infection control measures. Currently, few tests are capable of differentiating carbapenemase types, restricting the lab reports to their presence or not. The aim of this work was to raise antibodies and develop an ELISA test to detect KPC-2 and its D179 mutants. The ELISA-KPC test was designed using rabbit and mouse polyclonal antibodies. Four different protocols were tested to select the bacterial inoculum with the highest sensitivity and specificity rates. The standardisation procedure was performed using 109 previously characterised clinical isolates, showing 100% of sensitivity and 89% of specificity. The ELISA-KPC detected all isolates producing carbapenemases, including KPC variants displaying the ESBL phenotype such as KPC-33 and -66.

Mixed Messages

Efforts to promote disciplinary literacy can help students integrate knowledge with ways of doing and being within disciplinary settings. Yet, effectively facilitating disciplinary literacy, even within an upper-level undergraduate physics course like the one studied here, is surprisingly hard. This article qualitatively analyzes an instructor’s responses to student lab reports and finds that his comments to students focused on issues of correctness, often at the expense of larger rhetorical concerns of the text. Analysis also suggests that the instructor was thinking about many rhetorical aspects beyond surface-level errors as he read. Together, these findings suggest that efforts to promote disciplinary literacy, especially related to writing instruction, benefit from recognizing the layered contexts of activity in which writing and responding to lab reports take place. These findings hold value for secondary and post-secondary literacy instruction; in broad terms, this study may serve as a cautionary tale by illuminating the overlapping and competing value systems involved in disciplinary literacy efforts

Postoperative Hypocalcemia in Hyperthyroid Patients: The Parathyroids Aren't Always to Blame

IntroductionHypocalcemia is commonly reported after thyroidectomy and has multiple possible etiologies including: parathyroid devascularization, reactive hypoparathyroidism from relative hypercalcemia in thyrotoxicosis, and abrupt reversal of thyrotoxic osteodystrophy. In patients that are actively hyperthyroid and undergoing thyroidectomy, it is not known how many experience hypocalcemia from nonhypoparathyroidism etiologies. Therefore, our aim was to examine the relationship among thyrotoxicosis, hypocalcemia, and hypoparathyroidism. MethodsA retrospective review was performed of prospectively-collected data from all patients undergoing thyroidectomy for hyperthyroidism by 4 surgeons from 2016 to 2020. All patients carried a diagnosis of Graves’ disease or toxic multinodular goiter. Patient demographics, preoperative medications, laboratory reports, and postoperative medications were reviewed. Hypocalcemia within the first month of surgery despite a normal parathyroid hormone (PTH) level was the primary outcome of interest and was compared between patients with and without thyrotoxicosis. Secondary outcomes were duration of postoperative calcium use and the relationship between preoperative calcium supplementation and postoperative calcium supplementation. Descriptive statistics, Wilcoxon rank-sum, and chi-square tests were used for bivariate analysis, as appropriate. ResultsA total of 191 patients were identified, with mean age of 40.5 y (range 6-86). Most patients were female (80%) and had Graves’ disease (80%). At the time of surgery, 116 (61%) had uncontrolled hyperthyroidism (thyrotoxic group, Free Thyroxine >1.64 ng/dL or Free Triiodothyronine > 4.4 ng/dL), with the remaining 75 (39%) considered euthyroid. Postoperative hypocalcemia (calcium < 8.4 mg/dL) developed in 27 (14%), while hypoparathyroidism (PTH < 12 pg/mL) was observed in 39 (26%). Thyrotoxic patients comprised a majority of those with hypocalcemia (n = 22, 81%, P = 0.01) and hypoparathyroidism immediately following surgery (n = 14, 77%, P = 0.04). However, a majority of initially hypocalcemic, thyrotoxic patients had normal PTH values within the first month after surgery (n = 17, 85%), pointing to a potential nonparathyroid etiology. On bivariate analysis, no significant relationship was found for thyrotoxic patients with initial postoperative hypocalcemia (18%) and hypoparathyroidism <1-month after surgery (29%, P = 0.29) or between 1 and 6 mo after surgery (2%, P = 0.24). Of the 19 patients in the nonhypoparathyroidism group, 17 (89%) were off all calcium supplements by 6 mo postop. ConclusionsIn patients with hyperthyroidism, those in active thyrotoxicosis at time of surgery have a higher rate of postoperative hypocalcemia compared to euthyroid patients. When hypocalcemia lasts >1 mo postoperatively, data from this study suggest that hypoparathyroidism may not be the primary etiology in many of these patients, who typically require calcium supplementation no more than 6 mo postoperatively.

Infection Dynamics of Aspergillus fumigatus in Adults with Cystic Fibrosis (CF).

Aspergillus fumigatus (A. fumigatus) has emerged as a significant pathogen in patients with cystic fibrosis (CF) and currently is within the top five isolated organisms reported in several international CF patient registries. A. fumigatus has been attributed to disease progression, although its role remains controversial. There is a paucity of reports on its infection dynamics, it was the aim of this study to examine time to first laboratory reports of A. fumigatus acquisition and to correlate this with patient gender and cystic fibrosis transmembrane conductance regulator (CFTR) mutation type. One hundred adult (≥ 18years) CF patients were examined (50 females, 50 males; mean age 24.6years ± 6.25 (SD), median age 24years; maximum age 76years). CFTR mutation groups consisted (i) F508del/F508del homozygous (n = 45), (ii) F508del/other heterozygous (n = 45) and (iii) others (n = 10). CFTR mutation type, patient gender, presence/absence of A. fumigatus and time (months) to first isolation of A. fumigatus were examined. Microbiological data was examined from 100 patients from birth to present (31/12/2021), equating to 2455 patient years. A. fumigatus was isolated from 66/100 (66%) adult CF patients; (i) F508del/F508del homozygous (82%; 37/45), (ii) F508del/other heterozygous (56%; 25/45) and (iii) others (40%; 4/10). Within the F508del/other heterozygous group, 14 mutations were noted on the second allele, with R560T and R117H collectively accounting for 36% of the second mutations. Four unique allele/allele mutations were noted in the Other Mutations category. There was a trend to a higher A. fumigatus acquisition in F508del/F508del homozygous patients than with F508del/other patients (p = 0.0529). Of the 66 patients who were positive for A. fumigatus, 35(53%) were male and 31(47%) were female. The median and mean time to first isolation of A. fumigatus in all A. fumigatus-positive patients was 119.5months and 128months, respectively, shortest time was 12months, longest time 288months. There was a statistical significance in time-to-first isolation in relation to CFTR mutation group (p = 0.0272), whereby F508del homozygous individuals had their first isolation of A. fumigatus at 116.8 ± 7.9months (mean ± standard error of the mean (SEM)) and F508del heterozygous patients had their first isolate of A. fumigatus at 150.4months ± 13.7months (mean ± SEM), approximately 2.75years after their F508del homozygous peers. There was no significant difference (p = 0.12) in time to first acquisiton between males and females, whereby males had their first A. fumigatus isolate at 118 ± 9.4months, whereas females had their first A. fumigatus isolate at 140 ± 10.8months. The highest rate of first A. fumigatus isolation was from 4years until 16years and by the age of 16years, approximately 85% of A. fumigatus-positive patients had recorded their first A. fumigatus isolate. To minimise the risk of first acquisition of A. fumigatus, it is important that infection prevention educational messaging is delivered in the paediatric clinic, to enhance health literacy around A. fumigatus acquisition.

Documento de consenso para la determinación e informe del perfil lipídico en laboratorios clínicos españoles: ¿Qué parámetros debe incluir un perfil lipídico básico?

Cardiovascular diseases (CVD) continue to be the main cause of death in our country. Adequate control of lipid metabolism disorders is a key challenge in cardiovascular prevention that is far from being achieved in real clinical practice. There is a great heterogeneity in the reports of lipid metabolism from Spanish clinical laboratories, which may contribute to its poor control. For this reason, a working group of the main scientific societies involved in the care of patients at vascular risk, has prepared this document with a consensus proposal on the determination of the basic lipid profile in cardiovascular prevention, recommendations for its realization and unification of criteria to incorporate the lipid control goals appropriate to the vascular risk of the patients in the laboratory reports.

ANALYSIS OF EFFICIENCY OF SEWAGE TREATMENT PLANT USING DATA SCIENCE

As a study location, The Sewage Treatment Plant (STP) of New Naidu was chosen. The facility is close to Naidu Hospital. It can currently hold 115 MLD. The recorded 304 days of daily inflow data from the New Naidu Sewage Treatment Plant(From 1June 2021 to 31 March 2022) that was read by the flow meter on the daily basis was collected in order to undertake time series analysis and forecasting the inflow of wastewater. The average daily inflow was recorder&amp; the data that was obtained was then utilised to build the Autoregressive Integrated Moving Average Model (ARIMA) Model. The STP provided the lab report samples. Value of the various parameters, including pH, Total Suspended Solids (TSS), Chemical Oxygen Demand (COD), and Biological Oxygen Demand (BOD), which have a standard, were obtained to determine whether the water was reusable by making use of different classification techniques.

Comparative Study on Clinical Characteristics of COVID-19 Patients with or without Digestive Symptoms in Razi Hospital, Ahvaz, Khuzestan.

Most commonly reported clinical manifestations are fever, fatigue and dry cough. Interestingly, a small percentage of patients experience GI symptoms, with the most common being anorexia, diarrhea, nausea and vomiting. We aimed to conduct a comparative study on COVID-19 patients with or without gastrointestinal patients (GI). The pandemic of coronavirus disease 2019 (COVID-19) has emerged as a dire health problem, causing a massive crisis for global health. Collective data of clinical manifestations and laboratory reports of patients admitted to Razi Hospital, Ahvaz, Khuzestan, Iran, for two weeks were analyzed. Our results showed that GI symptoms are not statistically significant criteria to be predictive or prognostic factors in COVID-19 patients, although they are probably related to the acute or non-acute phase of the disease. Moreover, non-specific GI symptoms seem to result from cytokine storm that occurred during the disease. Therefore, our results did not support GI tract involvement as a common route of COVID- 19 infection. Maybe future research will shed light on why and how the gastrointestinal system becomes infected by COVID-19.

Candor in medical laboratory management “Quality is doing the right thing and making things right”

The practice of medicine in the modern era is exclusively evidence based, focuses on justifiable laboratory reports contributing effective and opportune patient management. For many years, clinical laboratories have picked up astounding significance in medical care services. Laboratory investigations are essential for medical diagnosis in patient care as well as medical research. Reliability of laboratory data/report is therefore of paramount importance. Good Clinical Laboratory Practices (GCLP) is essential to be implemented in the field of medical research and health care services to ensure reliability of laboratory data. Medical Laboratory Professionals endorse the decency, decorum, honour, morality, and self-respect of the profession and maintain a integrity, competence, reputation of honesty, authenticity, and accuracy. All laboratories engaged in testing of biological samples need to establish confidence in the quality and reliability of the results of these tests. In the current time, ethical concerns exist everywhere whether it is a medical field or life science. Medicine, at the center of which is the sick and dying man, has developed humanism and the morality of pity for the afflicted "Noli noceri",(First do no harm)"Salus aegroti - supreme lex"( let the welfare of the people be the supreme law ). It coincides with the motto of the World Academy of Medical Sciences mission. "Dedication to duty in a mission for mankind".

Disclosing own reasoning while appraising the students’ reasoning: implications for developments in formative assessment in science-engineering education

When instructors assess students’ laboratory reports to appraise the underlying scientific reasoning, they disclose their own concerns, epistemological assumptions and beliefs about science. The analysis of such assessments (i.e. rubric-centred scores and corresponding justificatory comments) offer a wealth of insights that can be re-engaged in further improvements of the assessment tool and procedure, and in developments in formative assessment more generally. Such insights include concerns exceeding the rubric’s descriptions (about meaningfulness, exhaustiveness, implicitness, connectivity, true inquiry, relevance), while differences among assessors are exposed (regarding epistemic values, approaches to scoring, sensitivity). This contribution is part of a broader effort to promote students’ conducive scientific thinking and deep-learning in science and engineering education. It addresses the question(s): what does the assessors’ reasoning tell us about the ways in which formative assessment is conducted, and could ideally be? The empirical investigation connects to existing knowledge, and discusses issues of representativeness and granularity in formative assessment. The paper elaborates on the design and use of the assessment tool, and presents evidence supporting context-bound recommendations and general conclusions. It is proposed that developments in formative assessment will benefit from reconceptualisation of assessment criteria, as the result of a co-design activity that engages with the assessors’ epistemological concerns.

Exploring natural language processing in mechanical engineering education: Implications for academic integrity

In this paper, the authors review extant natural language processing models in the context of undergraduate mechanical engineering education. These models have advanced to a stage where it has become increasingly more difficult to discern computer vs. human-produced material, and as a result, have understandably raised questions about their impact on academic integrity. As part of our review, we perform two sets of tests with OpenAI's natural language processing model (1) using GPT-3 to generate text for a mechanical engineering laboratory report and (2) using Codex to generate code for an automation and control systems laboratory. Our results show that natural language processing is a potentially powerful assistive technology for engineering students. However, it is a technology that must be used with care, given its potential to enable cheating and plagiarism behaviours given how the technology challenges traditional assessment practices and traditional notions of authorship.

Normal Total Leukocyte Count in Patients Despite Acute Appendicitis Clinically and Preoperatively

Background: The main objective of this study was to ascertain the proportion of individuals diagnosed with acute appendicitis who exhibited clinically and preoperatively normal levels of total leukocyte count. Methodology: During the months of June 2021 and March 2022, researchers from the Department of Surgery at Jinnah Postgraduate Medical Center in Karachi, Pakistan, conducted a prospective observational study. All the patients presented with an impression of acute appendicitis above the age of twelve were included. Complete history, clinical examination, emergency investigations including CBC, UCEs, Ultrasound, X-Rays, Alvarado score were recorded in a predefined pro forma. Patients with low ALVARADO score and normal TLC with signs and symptoms of acute appendicitis were compared with CRP levels which directed the decision of appendectomy rather than conservative management. Per operative findings of stages of acute appendicitis such as acute inflamed, suppurative, gangrenous and perforated appendix were also noted. Appendix was sent to the laboratory and histopathological reports of the specimen were assessed. Results: Patients diagnosed with acute appendicitis and subsequently operated on totaled 270 in the study, 156 (57.78%) were having and ALVARADO score of less than 7 mostly due to normal TLC, while 114 patients (42.22%) were having ≥ 7 ALVARADO score. Preoperatively and histopathological reports of 270 patients of appendicitis 25% patents were acutely inflamed/catarrhal stage , 15.5% gangrenous, 20.59% perforated, while higher number of patients i.e. 38.91 were suppurative appendicitis. Conclusion: Most patients presenting with symptoms of acute appendicitis have normal TLC, meaning low TLC. This needs to be confirmed by caring out by proper examinations and getting inflammatory markers or in cases confirmatory CT if diagnosis can not be made clinically or by lab investigations. Keywords: Appendicitis, ALVARADO score, C-reactive protein, total leukocyte count

Persisting Delirium as a Presenting Feature of an Underlying Myeloproliferative Neoplasm in Elderly

A 71 year old female presented with an unusually long course of persisting delirium and a rapid downhill functional decline. She presented with progressive symptoms over a course of year with confused behaviour, sleep disturbances, irrelevant talk and restlessness followed by difficulty in walking, falls, speech disturbances, generalized weakness of six months duration and decreased appetite with urinary and stool incontinence of 2 week duration. Her lab reports had shown consistently abnormal blood counts for 4 years before hospitalisation. The abnormalities from peripheral blood smear and GBP (general blood picture) showed elevated platelet count, total leucocyte count and decreased red blood cell count and haemoglobin level. Investigations for myeloproliferative neoplasm (MPN) included the Reflex profile (JAK mutations on qualitative RT-PCR), and bone marrow biopsy (increased megakaryocytes suggestive of Essential thrombocythemia). Patient was started on Oral Hydroxyurea along with oral anti platelet and hypolipidemic drugs. Six months post chemotherapy initiation remained asymptomatic.&#x0D; &#x0D; Keywords: elderly, delirium, myeloproliferative, neoplasia.

Erroneous Laboratory Reports - Leading to Catastrophic Patient Outcome

In recent years, increased timely and accurate laboratory test results are being produced and this has led to the clinical laboratory being recognized as the nerve centre of the diagnostic process [1]. Laboratory test results play a pivotal role in the diagnosis and management of a patient. Approximately 60–70% of medical decisions related to diagnosis and treatment depend on them [2].

Potential ChatGPT Use in Undergraduate Chemistry Laboratories

ChatGPT is a brand new, free AI chatbot that has the potential to produce a seismic shift in chemistry education, especially in written lab reports. An example is explored in which ChatGPT is used to write the discussion portion of a lab report. Ways to detect the use of ChatGPT are also discussed.

A study on diagnostic and prognostic significance of laboratory parameters and its correlation with HRCT of lung in Covid-19 patients

Coronaviruses had a wide range of symptoms from asymptomatic to severe illness and has caused significant morbidity and death among large population infected with this virus. To correlate CT severity score with each blood parameter like (TLC counts, Absolute neutrophil count, Absolute lymphocyte count, neutrophilic/lymphocytic ratio, quantitative D-dimer, ferritin, CRP, IL-6 and LDH). To assess diagnostic and prognostic significance of each parameter in predicting severity of disease.The present study was a 1-year prospective, a hospital-based study from 1 August 2020 to 31 July 2021 and included 100, COVID-19 confirmed cases. The clinical, radiological and laboratory reports were collected. The CT score were compared with different blood parameters. The results were analyzed statistically using correlation coefficient(r).27 patients having a CT severity score 1-10 were graded in mild category. 27 patients having CT severity score 11-15 were graded in moderate category.34 patients having CT severity score 16- 20 were graded as severe.12 patients having CT severity score 21-25 were graded as very severe. The present study showed raised TLC count &amp;#62; 11000 / µl in 35% patients suffering from COVID -19. Absolute neutrophil count &amp;#62; 7000/µl was seen in 50 % patients. 65% patients showed Absolute lymphocyte count &amp;#60;1000&amp;#62; 3.5 was seen in 83% patients. Raised D-Dimer &amp;#62;500 ng/ml was observed in 74 % patients. 92 % subjects showed raised Serum ferritin &amp;#62;150ng/ml. IL-6 &amp;#62;10pg/ml was seen in 92 % patients. Q-CRP &amp;#62;10 mg/l was seen in 97 % patients.HRCT chest severity score of patients with COVID-19 has positive correlation with various laboratory parameters and hence can be used as an indicator of disease severity. It can play a vital role in the management of COVID-19 and should be used for comprehensive evaluation.

Gamifying Physics Laboratory Work Increases Motivation and Enhances Acquisition of the Skills Required for Application of the Scientific Method

Although increasing student motivation is widely accepted to enhance learning outcomes, this relationship has scarcely been studied quantitatively. Therefore, this study aimed to address this knowledge gap by exploring the effects of gamification on students’ motivation and consequently their learning performance, regarding the proper application of the scientific method. To motivate students and enhance their acquisition of new skills, we developed a gamification framework for the laboratory sessions of first-year physics in an engineering degree. Data regarding student motivation were collected through a Likert-scale-type satisfaction questionnaire. The inter-item correlations and Cronbach’s alpha confirmed the internal consistency of the questionnaire. In addition, the learning outcome was assessed based on the students’ laboratory reports. Students participating in gamified activities were more motivated than those participating in non-gamified activities and obtained better learning results overall. Our findings suggest that gamified laboratory sessions boost students´ extrinsic motivation, and consequently inspire their intrinsic motivation and increase their learning performance. Finally, we discuss our results, with a focus on specific skills and the short- and long-term effects of gamification.

Clinical Significance of Anti-U1 Ribonucleoprotein Antibody Is Analyte Dependent: Implications for Laboratory Reporting, Interpretation, and Interassay Correlations.

Antibodies to U1 ribonucleoprotein (U1RNP) were first described more than 50 years ago, and although clinically relevant for antinuclear antibody-associated connective tissue disease (ANA-CTD), test results are challenging to interpret. To evaluate the impact of anti-U1RNP analyte diversity in the assessment of patients at risk for ANA-CTD. Two multiplex assays for U1RNP (Smith [Sm]/RNP and RNP68/A) were used to test serum specimens from consecutive patients (n = 498) under evaluation for CTD in a single academic center. Discrepant specimens were further tested for Sm/RNP antibody by enzyme-linked immunosorbent assay and the BioPlex multiplex assay. Data were evaluated for antibody positivity per analyte and their method of detection, correlations between analytes, and impact on clinical diagnoses through retrospective chart review. Of the 498 patients tested, 47 (9.4%) were positive in the RNP68/A (BioPlex) and 15 (3.0%) were positive in the Sm/RNP (Theradiag) immunoassays. U1RNP-CTD, other ANA-CTD, and no ANA-CTD were diagnosed in 34% (16 of 47), 12.8% (6 of 47), and 53.2% (25 of 47) of the cases, respectively. The prevalence of antibody by method in patients with U1RNP-CTD was 100.0% (16 of 16), 85.7% (12 of 14), 81.5% (13 of 16), and 87.5% (14 of 16) for RNP68/A, Sm/RNP BioPlex, Sm/RNP Theradiag, and Sm/RNP Inova, respectively. For other ANA-CTD and no ANA-CTD, the highest prevalence was observed with RNP68/A; all others had comparable performance. In this study, the overall performance characteristics of Sm/RNP antibody assays were comparable; however, the RNP68/A immunoassay was very sensitive but less specific. In the absence of harmonization, reporting the type of U1RNP analyte in clinical testing may be useful in guiding interpretation and interassay correlations.

AACC Guidance Document on Cervical Cancer Detection: Screening, Surveillance, and Diagnosis.

Persistent genital infection with high-risk human papilloma virus (hrHPV) causes the vast majority of cases of cervical cancer. Early screening, ongoing surveillance, and accurate diagnosis are crucial for the elimination of cervical cancer. New screening guidelines for testing in asymptomatic healthy populations and management guidelines for managing abnormal results have been published by professional organizations. This guidance document addresses key questions related to cervical cancer screening and management including currently available cervical cancer screening tests and the testing strategies for cervical cancer screening. This guidance document introduces the most recently updated screening guidelines regarding age to start screening, age to stop screening, and frequencies of routine screening as well as risk-based management guidelines for screening and surveillance. This guidance document also summarizes the methodologies for the diagnosis of cervical cancer. Additionally, we propose a report template for human papilloma virus (HPV) and cervical cancer detection to facilitate interpretation of results and clinical decision-making. Currently available cervical cancer screening tests include hrHPV testing and cervical cytology screening. The screening strategies can be primary HPV screening, co-testing with HPV testing and cervical cytology, and cervical cytology alone. The new American Society for Colposcopy and Cervical Pathology guidelines recommend variable frequencies of screening and surveillance based on risk. To implement these guidelines, an ideal laboratory report should include the indication for the test (screening, surveillance, or diagnostic workup of symptomatic patients); type of test (primary HPV screening, co-testing, or cytology alone); clinical history of the patient; and prior as well as current testing results.

Post-COVID-19 Inappropriate Sinus Tachycardia Treated with Naja tripudians: A Case Report

Abstract Background/Introduction The majority of people who recover from coronavirus disease 2019 (COVID-19) experience tachycardia and/or palpitations after slight activity or at rest. In some cases, the resting heart rate may remain above 100 beats per minute or get exacerbated out of proportion by slight activity. This persistent tachycardia appearing in post-COVID-19 may clinically present as inappropriate sinus tachycardia (IST). The common mode of diagnosis is electrocardiography after excluding other causes of tachycardia. So far, there is no reported study evaluating individualised homoeopathic intervention in post-COVID-19 IST in peer-reviewed homoeopathic journals. Method This report describes a case of tachycardia and palpitations developed after COVID-19. After complete evaluation of laboratory reports and clinical examination, the diagnosis of IST was made. After detailed case taking and repertorisation, Naja tripudians was prescribed as an individualised homoeopathic remedy to treat the case. Outcomes were assessed objectively on the basis of electrocardiography and subjectively using outcome related to impact on daily living (ORIDL) scale. Result There was a marked subjective improvement along with objective improvement as evidenced by electrocardiography images. The case showed a 4+ outcome on ORIDL scale. The Modified Naranjo Criteria total score was +9 out of a possible +13, providing definite evidence to attribute the clinical outcome with the homoeopathic intervention. Conclusion This single case demonstrates that Naja tripudians, a rarely used drug, may be helpful in treating post-COVID-19 IST. Clinical trials in this direction are required to conclude firm causal attribution.