L-ornithine Monohydrochloride Research Articles

Bipolar Membrane Electrodialysis for Direct Conversion of L-Ornithine Monohydrochloride to L-Ornithine.

In this study, bipolar membrane electrodialysis was proposed to directly convert L-ornithine monohydrochloride to L-ornithine. The stack configuration was optimized in the BP-A (BP, bipolar membrane; A, anion exchange membrane) configuration with the Cl- ion migration through the anion exchange membrane rather than the BP-A-C (C, cation exchange membrane) and the BP-C configurations with the L-ornithine+ ion migration through the cation exchange membrane. Both the conversion ratio and current efficiency follow BP-A > BP-A-C > BP-C, and the energy consumption follows BP-A < BP-A-C < BP-C. Additionally, the voltage drop across the membrane stack (two repeating units) and the feed concentration were optimized as 7.5 V and 0.50 mol/L, respectively, due to the low value of the sum of H+ ions leakage (from the acid compartment to the base compartment) and OH- ions migration (from the base compartment to the acid compartment) through the anion exchange membrane. As a result, high conversion ratio (96.1%), high current efficiency (95.5%) and low energy consumption (0.31 kWh/kg L-ornithine) can be achieved. Therefore, bipolar membrane electrodialysis is an efficient, low energy consumption and environmentally friendly method to directly convert L-ornithine monohydrochloride to L-ornithine.

The influence of l-ornithine monohydrochloride on growth and various properties of ammonium dihydrogen phosphate crystals

In the present work, an aim is to investigate the influence of l-Ornithine monohydrochloride (LOMHCl) doping on structural, optical and electrical properties of pure ADP crystals. It is analyzed by following various characterizations. Pure and LOMHCl doped ammonium dihydrogen phosphate (ADP) crystals have been grown by using slow solvent evaporation technique at room temperature in dust free laboratory. The powder XRD patterns show the single phase nature of pure and doped ADP crystals. The average crystallite size and strain are found from X-ray peak broadening analysis. The UV–Vis spectra indicate slight decrement in the transmittance and band gap values of doped ADP crystals. The SHG efficiency of doped ADP crystals found to increase compared to pure ADP and pure KDP. Z-scan analysis shows increased nonlinear optical properties of doped ADP crystals. The dielectric constant and loss plots show usual behavior with respect to frequency and reduction in the values of doped ADP. The Jonscher's power is studied for ac conductivity. The complex impedance and modulus plots show single semicircle for both pure and doped ADP due to grain contribution only. The stretch exponent parameter values indicate the non-Debye type relaxation process.

Growth and characterization of l-ornithine monohydrochloride single crystal doped with Co2+ and Mn2+ ions for NLO applications

Growth and characterization of l-ornithine monohydrochloride single crystal doped with Co2+ and Mn2+ ions for NLO applications

Quantitative analysis of nutrients for nucleosides, nucleobases, and amino acids hidden behind five distinct regions-derived Poria cocos using ultra-performance liquid chromatography coupled with triple-quadrupole linear ion-trap tandem mass spectrometry.

Poria cocos is an edible fungus used as a health product and traditional Chinese medicinal preparation. Nevertheless, little is known about its nutrients. In this study, ultra-high performance liquid chromatography coupled with triple-quadrupole linear ion-trap tandem mass spectrometry was conducted to quantify nucleosides, nucleobases, and amino acids in 32 batches of Poria cocos samples collected from Anhui, Sichuan, Hubei, Hunan, and Guizhou. Subsequently, the linearity, precision, repeatability, stability, and recovery of our methods were validated. Samples from different regions were clearly separated by partial least squares discriminant analysis and cluster analysis. Our results suggested that Poria cocos samples from different geographical environments differed in nucleosides, nucleobases, and amino acids. The plot of variable importance for projection disclosed differential compositions of L-Leucine, Uridine, L-Asparagine, L-Glutamine, L-phenylalanine, L-Ornithine monohydrochloride, L-Hydroxyproline, Taurine, and Inosine in Poria cocos from five regions. We found the highest content of total analytes, total amino acids, and total non-essential amino acids in Poria cocos from Anhui, total essential amino acids in the Sichuan samples, and total nucleosides in the Hunan samples. Overall, we determined the content of Poria cocos-derived nucleosides, nucleobases, and amino acids, providing the foothold for further chemical mining and use of Poria cocos.

L-Ornithine Monohydrochloride Doped Zinc Tris-Thiourea Sulphate Single Crystals for NLO Applications

In the current study, transparent and bulk sized L-ornithine monohydrochloride (LOMHC) added zinc tris-thiourea sulphate (LOMHC-ZTS) single crystals are synthesized successfully by utilizing slow evaporation solution technique (SEST). The obtained crystals are belonging to the orthorhombic system confirmed by single crystal X-ray diffraction technique (SXRD). The strain produced due to dopant inside the crystal and crystallite size is estimated by using powder X-ray diffraction (PXRD) data. The impact of LOMHC on the optical properties of ZTS has been studied in detail. It is observed that the energy gap and transmittance are improved; refractive index and extinction coefficient is decreased upon doping. The dielectric study emphasizes that the LOMHC-ZTS crystal is good in the applicability for NLO device applications. The grown crystals showed improvement in the thermal stability upon doping of LOMHC. The flexibility of the grown crystals in terms of hardness behavior of LOMHC-ZTS is predicted by Vicker’s microhardness test; with this, yield strength and stiffness constant are calculated. This test revealed that LOMHC-ZTS belongs to soft material category possessing improved mechanical properties. SHG efficiency of ZTS is increased relatively upon the inclusion of LOMHC. These results favor the competency of LOMHC doped ZTS crystal in various NLO and laser assisted applications.

Third order nonlinear optical, spectral, dielectric, laser damage threshold, and photo luminescence characteristics of an efficacious semiorganic acentric crystal: L-Ornithine monohydrochloride

The efficient acentric L-ornithine monohydrochloride (LOMHCl), which belongs to the trait of semiorganic category and depicts nonlinear optical characteristics, was grown-up by the process of slow evaporation. The crystal structure and crystallinity of LOMHCl was established by the process of single crystal and powder X-ray diffraction. Single XRD affirm that LOMHCl crystallizes in the system of monoclinic with P21 as acentric space group. The examination of FTIR was done to ascertain the existence of various functional groups in LOMHCl. UV–Vis spectral analysis substantiates its optical quality and the optical constants were also assessed. Photoluminescence process elucidates its emission characteristics and its lifetime is also determined. LOMHCl discloses exquisite resistance to laser radiation having threshold up to 2.69 GW/cm2. The SEM analysis highlights its surface topography. The mechanical stability has been attested by the analysis of microhardness and several mechanical parameters are also estimated. The investigation of dielectric characteristics of LOMHCl was also accomplished. The studies on second and third order nonlinearity were established by the method of Kurtz–Perry and Z-scan which facilitates its utility in the field of nonlinear optics.

Investigations on crystal perfection, mechanical and thermo-electric properties of l-ornithine monohydrochloride single crystal: A promising material for nonlinear optical applications

l-Ornithine monohydrochloride (LOMHCl) single crystal is a potential material for non linear optical and opto-electronic applications. In the present study, good quality single crystals were grown by slow evaporation solution technique at room temperature. The bulk single crystals were subjected to various characterization analyses in order to investigate and elaborate the important properties of the title compound. Crystal defects were examined by employing high-resolution X-ray diffraction (HRXRD) technique and found good crystalline perfection. Surface morphology was assessed by SEM analysis. To investigate the mechanical properties at nanoscale, nanoindentation experiment have been performed. Various mechanical properties like hardness, stiffness, Young's modulus were studied and found that both hardness and Young's modulus depends upon the peak load. Photo-acoustic characterization and DSC were performed to investigate the thermal properties like thermal diffusivity, thermal conductivity, thermal effusivity and specific heat capacity. These results confirm that the title compound has high stability as compared to other single crystals of amino acids family.

Spectroscopic and thermo- electrical investigation of single crystals of l-Ornithine monohydrochloride grown by SEST

l- Ornithine Mono Hydrochloride (LOMHCl) single crystals were grown successfully by slow evaporation solution technique (SEST). Optically transparent and desirable quality single crystals of LOMHCl having dimensions 30×11×5mm3 were obtained in a span of 16days. The grown crystals were subjected to powder X-ray diffraction and the results confirmed its crystal structure as well as structural parameters. Mechanical strain present in the crystal has been calculated by Williamsons-Hall model from XRD data. This positive value of mechanical strain (+3.3×10−3) indicate that the grown crystals are having grain boundaries. The presence of functional groups was confirmed by FTIR and Raman analysis. In these spectra, no extra peak is observed that confirms identity of the compound. The CHN analysis also confirmed the percentage wise elemental composition of carbon, hydrogen and nitrogen. Optical behavior was examined by UV–vis-NIR spectrophotometer. Various optical parameters like optical band gap, refractive index, reflectance and optical dielectric constant were calculated 4.76eV, 1.663 and 2.88 respectively. In order to know its thermal properties TGA/DTA studies were carried out. From etching and micro hardness studies the mechanical properties were analyzed to investigate its suitability for device fabrication. In addition to this, dielectric constant and dielectric loss were measured at different temperatures as a function of frequency over the frequency range 10Hz–10 KHz. Plasma energy, Penn gap energy, Fermi gap energy and polarizability were also calculated using Clausius Mossotti relations.

A physico-chemical approach to study the experimental and theoretical properties of l-ornithine monohydrochloride: An organic nonlinear optical material

In the current work the authors report the experimental and theoretical investigation on l-ornithine monohydrochloride (LOHCL). Single crystals of LOHCL were grown by slow cooling technique and its crystal system was confirmed by powder X-ray diffraction analysis. The crystalline perfection was evaluated by high-resolution X-ray diffraction analysis which indicates that the crystalline perfection of the grown crystal is fairly good. Vibrational modes of LOHCL were identified by experimentally recorded and theoretically calculated FT-Raman and IR spectrums and found in good agreement with the reported values. Optical absorbance and reflectance were recorded by using UV–Vis–NIR spectrophotometer and various optical parameters were calculated. Detailed theoretical analysis was done by density functional theory (DFT) and time dependent TD-DFT using B3LYP/6-31G(d,p) level of method. HOMO-LUMO gap was found to be 6.09 eV whereas by experiment it is 4.8 eV. The excited state is more polar in comparison to ground state during excitation, dipole moment increases from 3.06 D in ground state to 3.90 D in excited state. The average polarizability (αtot), anisotropy of polarizability (Δα), first static and second order hyperpolarizability (βtot, β0, γ) were calculated. The total first hyperpolarizability of LOHCL is found to be 2 times higher than prototype urea molecule which is very promising for nonlinear optical applications.

Identification of Wild Yeast Strains and Analysis of Their β-Glucan and Glutathione Levels for Use in Makgeolli Brewing

Makgeolli, also known as Takju, is a non-filtered traditional Korean alcoholic beverage that contains various floating matter, including yeast cells, which contributes to its high physiological functionality. In the present study, we assessed the levels of β-glucan and glutathione in various yeast strains isolated from traditional Korean Nuruk and selected a β-glucan- and glutathionerich yeast strain to add value to Makgeolli by enhancing its physiological functionality through increased levels of these compounds. Yeast β-glucan levels ranged from 6.26% to 32.69% (dry basis) and were strongly species-dependent. Dried Saccharomyces cerevisiae isolated from Nuruk contained 25.53 μg/mg glutathione, 0.70 μg/mg oxidized glutathione, and 11.69 μg/ g and 47.85 μg/g spermidine and L-ornithine monohydrochloride, respectively. To produce functional Makgeolli, a β-glucan- and glutathione-rich yeast strain was selected in a screening analysis. Makgeolli fermented with the selected yeast strain contained higher β-glucan and glutathione levels than commercial Makgeolli. Using the selected yeast strain to produce Makgeolli with high β-glucan and glutathione content may enable the production of functional Makgeolli.

Effect of N5+ ion irradiation on l-ornithine monohydrochloride single crystals: an organic nonlinear optical material

In this work, the authors have grown good-quality single crystals of l-ornithine monohydrochloride (LOHCL), an organic nonlinear optical material, in the aqueous solution by the slow cooling technique. N5+ ion irradiation of three different doses (i.e. 1 × 1016, 5 × 1016 and 1 × 1017 ions/cm2) at room temperature was done on the cut and polished crystal specimen of appropriate size from the grown crystal. A detailed study of FT-Raman spectroscopic was carried out to see the effect of irradiation on structure and vibrational modes of the LOHCL crystal. The results revealed that there is no structural modification even at high doses except the variation in peak intensity, which indicates that the grown crystals of LOHCL have good stability and also confirms that the nitrogen ions do not substitute into the crystal lattice. The UV–Vis–near-infrared spectroscopic study was done on all the samples to see the effect of irradiation and various optical parameters such as transmittance (∼50–70%), absorption coefficient, energy band gap (∼4.75–4.96 eV), extinction coefficient, refractive index (∼1.31–1.24), optical permittivity (∼1.7–1.6) and susceptibility (∼0.7–0.6). The calculated optical parameters were found to vary with change in doses.

Genotoxicity and subchronic oral toxicity of l-ornithine monohydrochloride

l-Ornithine monohydrochloride was evaluated in two in vitro genotoxicity assays and a rat 90-day oral toxicity study.No evidence of genotoxicity was observed in the reverse bacterial mutation assay or the chromosome aberration test at doses of up to 5000μg/plate or 1686μg/mL, respectively, both in the presence and absence of metabolic activation.Rats were administered l-ornithine monohydrochloride at dietary concentrations of 0 (basal diet), 1.25%, 2.5%, or 5.0% for 90days. No changes in body weight, food consumption, ophthalmoscopy, or hematology were observed. Transient increases in water intake and urinary volume, and a decrease in specific gravity were observed in males receiving 5.0% l-ornithine monohydrochloride; however, these were likely attributable to the central role of ornithine in the urea cycle and the consequent increase in urea production. A decrease in serum chloride concentration and an increase in urinary chloride excretion were observed; however, these were likely attributable to administration of the hydrochloride salt of ornithine and were not considered to be of any toxicological significance. No remarkable findings were noted at necropsy.Based on the results of the study, a no-observed-adverse effect level (NOAEL) of 3445 and 3986mg/kg body weight/day was established for male and female rats.

Thermal, mechanical, electrical, linear and nonlinear optical properties of a nonlinear optical l-ornithine monohydrochloride single crystal

Optically transparent semiorganic nonlinear optical bulk single crystal of l -ornithine monohydrochloride (LOMHCL) of dimension 11×3×2 mm 3 has been grown from its aqueous solution by slow solvent evaporation technique. The grown crystal was characterized by powder X-ray diffraction to confirm the crystal structure. Investigation has been carried out to assign the vibrational frequencies of the grown crystals by Fourier transform infrared spectroscopy technique. Thermal behavior of the grown crystals was studied by thermogravimetric analysis. The second harmonic generation (SHG) efficiency of LOMHCL was determined by Kurtz and Perry powder technique. The optical absorption study confirms the suitability of the crystal for device applications. The mechanical properties of the grown crystals have been studied using Vickers microhardness tester. Dielectric and photoconductivity studies are also carried out for the grown samples.

Crystal growth, structural, optical, mechanical and thermal properties of a new nonlinear optical single crystal: l-Ornithine monohydrochloride

Amino acid family crystals exhibit excellent nonlinear optical and electro optical properties. l-Ornithine monohydrochloride single crystal, belongs to the amino acid group, was grown by the slow evaporation solution growth technique at room temperature. The grown crystals were characterized by single crystal and powder X-ray diffraction analysis, Fourier transform infrared (FTIR) spectroscopy, TGA, DTA and DSC analyses. UV–vis–NIR spectrum shows excellent transmission in the UV, visible and NIR region (300–1600 nm). The mechanical properties of grown crystals were studied using Vickers microhardness tester. Its second harmonic generation efficiency was tested using Nd:YAG laser and is 1.25 times that of KDP.