Abstract Qatar's future vision, named Qatar 2030, is forecasting an economy based on knowledge and creativity rather than depletable natural carbon resources. Knowledge and creativity are perhaps the most important factors in the future of a city's economy, and there is a growing interest in the concept of the “knowledge and creative city”. A knowledge and creative city is not just a regular city. It is a growing space of exchange and optimism in which each and everyone can devote themselves to personal and collective projects and aspirations in a climate of dynamism, harmony, and creativity. The main purpose of this research is to explore the ‘knowledge city’ concept in depth. It will discuss the principles of a knowledge city, and portray its distinguishing characteristics and processes. A solid argument will be constructed to illustrate that the concept of knowledge cities is rooted in the urban, cultural structure of traditional Arab cities. Therefore an attempt to foster this concept in today's Arab/Middle Eastern cities would not be possible by building isolated technological statements scattered around the city. Alternatively, the rise of the network society, global networks, linked cities and the existence of smart communities should construct the basis for shaping Arab Knowledge Cities. A focus on Doha as an emerging knowledge and creative city amid the Middle Eastern cities will be included to examine the main hypothesis of the research. ‘What are the qualities of future cities?’ becomes a crucial question and its answer creates a challenge for architects, urban designers, planners, developers, and decision makers around the world. This research will answer this question by articulating a new matrix for knowledge and creative city formation. Doha will be used as a model for such a new paradigm of knowledge-based urban design and development in the Middle East. The Middle Eastern cities are not only exceptions, but would require major social transformations to join the knowledge economy era.