AbstractThe purpose of this study was to analyze relevant initial-implantation biomechanical properties of five knotless suture anchors available for use in acetabular labral repair. Five knotless suture anchor constructs were tested: Arthrex PushLock 2.9, Arthrex PushLock 2.4, Arthrex SutureTak 3.0, Stryker CinchLock SS 2.4, and Stryker CinchLock Flex 2.4. Anchors were placed in synthetic bone blocks and in acetabular bone of cadaveric specimens. Constructs were subjected to cyclic and load-to-failure (LTF) testing. Displacement at 1, 100, 250, and 500 cycles, yield load, ultimate load, and failure mode were compared with statistically significant (p < 0.005) differences. PushLock 2.9 mm and CinchLock SS 2.4 anchor constructs had significantly less displacement than PushLock 2.4 mm after 1 cycle (p = 0.017) and 500 cycles (p = 0.043). Excluding “tare” displacement after the first cycle, all anchor constructs were associated with less than 2.0 mm of displacement after 500 cycles. Arthrex PushLock 2.4 and SutureTak 3.0 had the highest number of failures prior to completing cyclic loading. Arthrex PushLock 2.9 was associated with the highest LTF in cadaver (p = 0.00013) and synthetic (p = 0.009) bone models. Most common failure mode in cadaver bone was eyelet failure for all anchor types. Knotless suture anchors used for arthroscopic hip surgery (2.9 mm PushLock, 2.4 mm PushLock, 3.0 mm SutureTak, 2.4 mm CinchLock SS, and 2.4 mm CinchLock Flex) were associated with material properties that met or exceeded the reported thresholds for successful periarticular soft tissue repair surgeries. Based on cyclic and LTF testing in synthetic bone blocks and cadaveric acetabulums, 2.9 mm PushLocks and 2.4 mm CinchLock SS anchors may have potential biomechanical advantages over the other constructs tested. Further functional ex vivo and preclinical animal model studies are recommended to further characterize suture anchor constructs designed for acetabular labrum repair. These results provide novel and relevant biomechanical testing data that contribute to assessing knotless suture anchor constructs for use in acetabular labral repair.