The present study proposes the use of a new ultrasonic irradiation method to enhance permeability and desorption for gas recovery from low-permeability coal reservoirs. A triaxial stress ultrasonic irradiation test apparatus was developed specifically for coal, considering the properties of gas adsorption, migration, and sound intensity, and providing a simultaneous measurement of gas flux, to investigated the deformation and temperature of coal samples obtained from the Fuxin coal field by permeability and desorption experiments. With the ultrasonic irradiation duration, the permeability of coal improved gradually with unequal variation, accompanied by the Klinkenberg effect where it decreased rapidly and then increased slowly with increasing gas pressure. The ability to desorb coal was enhanced by higher sound intensity ultrasound irradiation, and the volume of gas desorption was much greater than that of the sample without mange, the temperature and strain were demonstrated as a “J shaped” curve. An X-ray computer tomography (CT) technique was used to visualise the meso- or macro-cracks in the coal sample at pre- and post- ultrasonic irradiation, consequently, fractures expanded under the irradiation of ultrasonic waves. A permeability and desorption model was developed to describe the improvement of coal seam gas production capacity under ultrasonic irradiation, which introduced effective sound pressure.