Kinetic Analysis Research Articles

Synergistic effect of holey graphene and CoSe2-NiSe2 heterostructure to enhance fast Na-ion transport

Inspired by the “Barrel principle” and based on the working principle of the “rocking chair”. We propose two shortboards that “bulk diffusion rate” and “ion reaction rate”, which affect the fast charging of sodium ion batteries (SIBs). The holey reduced graphene oxide (HrGO) with abundant nanopores provides longitudinal diffusion channels, enabling rapid Na+ diffusion along this direction, which solves the shortboard of bulk diffusion rate. Additionally, heterojunctions are considered a viable approach for enhancing fast Na+ storage performance by providing more storage sites and accelerating the kinetics of Na+ reaction, which solve the shortboard of ion reaction rate. Herein, we construct HrGO combined with CoSe2-NiSe2 heterojunctions has been rationally fabricated to synergistically enhance the ionic and electronic diffusion kinetics. As expected, the CoSe2-NiSe2/HrGO anode in SIBs shows an excellent fast-charging performance (392.4mAh/g at 15 A/g), surpassing most Co/Ni-based selenide anodes. Additionally, the assembled CoSe2-NiSe2/HrGO||NVP full cell delivers a high specific capacity of 116.1 and 95.4mAh/g at 0.1 and 20C, respectively, coupled with 97.8 % capacity retention rate for 100 cycles. Furthermore, we elucidate the mechanism of Na+ storage and fast transport through electrochemical kinetic analysis, in situ and ex situ characterizations, density functional theory (DFT) calculations, and distribution of relaxation times (DRT). Importantly, this study provides theoretical insights into accelerating rapid Na+ transfer.

Directly Regenerating of Spent LiCoO2 with Gradient F-doped Subsurface towards Ultra-stable Storage Properties.

As great potential recycling strategy, the direct regeneration of spent LiCoO2 (LCO) is beneficial for lowering environmental pollutions and promoting global sustainability. However, owing to the using of binder and electrolyte, some fluorine impurities would be remained into spent materials. Considering the doping behaviors of F-elements, their suitable content introducing would facilitate the energy-storage abilities of regenerated LCO. Herein, through the tailored introduction of F-elements, spent LCO are successfully regenerated with physical-chemical evolutions. Benefitting from the existed oxygen vacancies, the diffusion energy-barrier of F-elements is reduced from 1.73 eV to 0.61 eV, facilitating the establishment of gradient F-doped subsurface, along with the formation of rigid CoO5F. Meanwhile, excess F-elements (1 wt.%, as a threshold) lead to the formation of LiF passivation layer on the surface. Thus, the as-optimized sample displays a considerable capacity of 154.4 mAh g-1 even at 5.0 C, with retention rate (88.3%) in 3.0~4.5V. Supported by detailed electrochemical and kinetic analysis, the structural advantages are confirmed to boost the improved redox activity of Co-ions and the alleviating of irreversible oxygen-release. Give this, the work is anticipated to reveal the evolutions of regenerated LCO with the introduced F-elements, whilst providing the practical regeneration strategies toward excellent high-voltage properties.

Directly Regenerating of Spent LiCoO2 with Gradient F‐doped Subsurface towards Ultra‐stable Storage Properties

As great potential recycling strategy, the direct regeneration of spent LiCoO2 (LCO) is beneficial for lowering environmental pollutions and promoting global sustainability. However, owing to the using of binder and electrolyte, some fluorine impurities would be remained into spent materials. Considering the doping behaviors of F‐elements, their suitable content introducing would facilitate the energy‐storage abilities of regenerated LCO. Herein, through the tailored introduction of F‐elements, spent LCO are successfully regenerated with physical‐chemical evolutions. Benefitting from the existed oxygen vacancies, the diffusion energy‐barrier of F‐elements is reduced from 1.73 eV to 0.61 eV, facilitating the establishment of gradient F‐doped subsurface, along with the formation of rigid CoO5F. Meanwhile, excess F‐elements (1 wt.%, as a threshold) lead to the formation of LiF passivation layer on the surface. Thus, the as‐optimized sample displays a considerable capacity of 154.4 mAh g‐1 even at 5.0 C, with retention rate (88.3%) in 3.0~4.5V. Supported by detailed electrochemical and kinetic analysis, the structural advantages are confirmed to boost the improved redox activity of Co‐ions and the alleviating of irreversible oxygen‐release. Give this, the work is anticipated to reveal the evolutions of regenerated LCO with the introduced F‐elements, whilst providing the practical regeneration strategies toward excellent high‐voltage properties.

Correlative electron microscopy of discontinuous precipitation

This paper presents a comprehensive study on discontinuous precipitation (DP) in Al-22 at.% Zn alloy, leveraging the correlative and synergic effects of advanced microscopy and modelling techniques. The study is structured into three pivotal steps: in-situ scanning electron microscopy combined with an energy backscattered diffraction analysis for real-time monitoring and an analysis of DP reaction kinetics and grain boundary misorientations; transmission electron microscopy and an energy X-ray dispersive microanalysis for detailed observation of solute-depleted α and solute-rich β lamellae, offering insights into the kinetics of the reaction front (RF) and solute concentration profiles; and a sophisticated modelling approach addressing the limitations of direct observation methods by simulating solute concentration changes within αphase lamellae during RF go-and-stop cycles. This multifaceted approach elucidates the nuances of DP mechanisms, from the nucleation and growth of precipitates to the estimation of instantaneous RF velocity and the impact of grain boundary misorientations. The integration of these methodologies enhances our understanding of DP kinetics and morphology at both meso- and nanoscales, highlighting the significant role of correlative microscopy in metallurgical research. The findings not only deepen our grasp of the fundamental mechanisms driving DP reactions but also provide a valuable comparison framework for experimental data, potentially guiding the development and optimization of metallurgical processes.

Insight into Limited Recoveries in Printed Circuit Board Leaching: Evidence of Gold Adsorption Loss to Polymeric Particles

AbstractSustainable resource utilization ultimately depends on total recovery during recycling operations. PCB leach pulp for target metal recovery contains ceramic and polymeric particles resistant to reagent attack. The investigation herein shows the physicochemical behavior of five polymeric particles namely green, red, black, white, and blue in gold chloride complex [AuCl4]− solution. Gold concentration change was monitored over time to study how the gold solution interacted with the polymeric particles and how the interaction conforms to known adsorption isotherm and kinetic models. The black and green polymeric particles have the highest adsorption per unit mass to about 1.81 mg/g and 2.18 mg/g, respectively. Four adsorption kinetic models evaluated for insight on the adsorption mechanism observed show Elovich and pseudo-second-order (PSO) models fit the kinetic data best compared to other models with correlation coefficients of 0.9867 and 0.9863, respectively. Of the seven adsorption isotherm models evaluated, Sips model shows best fit for the isotherm data with correlation coefficients of 0.9727 and 0.9328 for green and black particles, respectively. Isotherm and kinetic model analyses of the experimental data indicated physisorption and chemisorption as driving mechanism of the interaction between PCB polymeric particles and gold chloride complex aliquot. Graphical Abstract

Low-temperature reactivity, extinction, and heat release rate of non-premixed cool flame at elevated pressures

Understanding the fundamental characteristics of high-pressure cool flames is crucial for the development of advanced and efficient low-temperature combustion engine technologies. The pressure dependency of multi-oxygen addition branching reactions in low-temperature chemistry significantly influences the dynamics, structure, and reactivity of cool flame. This study investigates the non-premixed cool flame of diethyl ether (DEE) at elevated pressures. The results show that pressure rise promotes low-temperature chemistry and significantly extends the extinction limit of cool flame. It is found that the cool flame heat release rate is correlated with the product of pressure and the square root of the pressure-weighted strain rate, Q∼aP·P, which is different from that of hot flames, Q∼aP. The radical index concept for atmospheric cool flames is extended to high-pressure cool flames allowing to decouple the mass and thermal transports from the chemical kinetics term to evaluate the fuel reactivity at elevated pressures. The radical index shows that the low-temperature reactivity of DEE is enhanced with the pressure and is higher than n-dodecane by a factor of 19, 18.3, and 16.4 for 1, 3, and 5 atm, respectively. Kinetic analysis reveals that pressure rise results in QOOH stabilization and promotions of the second O2 addition and the chain-branching reaction pathway for multiple OH radical productions.

Axial Coordination Engineering on Fe‒N‒C Materials for Oxygen Reduction: Insights from Theory.

Axial coordination engineering has emerged as an effective strategy to regulate the catalytic performance of metal‒N‒C materials for oxygen reduction reaction (ORR). However, the ORR mechanism and activity changes of their active centers modified by axial ligands are still unclear. Here, a comprehensive investigation of the ORR on a series of FeN4‒L moieties (L stands for an axial ligand) is performed using advanced density functional theory (DFT) calculations. The axial ligand has a substantial effect on the electronic structure and catalytic activity of the FeN4 center. Specially, FeN4‒C6H5 is screened as a promising active moiety with superior ORR activity, as further revealed by constant-potential calculations and kinetic analysis. The enhanced activity is attributed to the weakened *OH adsorption caused by the altered electronic structure. Moreover, microkinetic modeling shows that at pH = 1, FeN4‒C6H5 possesses an impressive theoretical half-wave potential of ~1.01 V, superior to the pristine Fe‒N‒C catalysts (~0.88 V) calculated at the same level. These findings advance the understanding of the ORR mechanism of FeN4‒L and provide guidance for optimizing the ORR performance of single-metal-atom catalysts.

Microstructural Changes and Kinetic Analysis of Oxidation Reaction in Coal–Oil Symbiosis

Microstructural Changes and Kinetic Analysis of Oxidation Reaction in Coal–Oil Symbiosis

Dielectric‐Controlled Ultrafast Twisted Intramolecular Charge‐Transfer VS trans to cis Isomerization Pathways in a Push‐Pull Stilbene: Global Analysis Perspectives

We explore excited‐state dynamics of 4,4’‐dimethylaminonitrostilbene (DNS), a push‐pull stilbene, undergoing twisted intramolecular charge transfer and/or trans to cis isomerization, which is dependent on solvent polarity. We show how global analysis of femtosecond pump/broadband‐probe data aids in elucidating the involvement of interconverting conformers and/or isomers, often unexplored in single‐wavelength kinetic analysis.

Enrichment of a Nigerian plagioclase-rich feldspar ore by methanesulfonic acid solution for improved industrial application: kinetic and statistical analysis

ABSTRACT To date, feldspar is a pivotal mineral, with projections indicating a substantial gap between supply and demand in the near future. This surge can be attributed to the increasing need for ceramic tiles, the growing demand for electronic devices, and advancements in glass manufacturing, which have led to the development of a specialised hydrometallurgical process capable of producing iron-free feldspar materials tailored for the ceramics and glass industries. Consequently, the enrichment of a locally sourced plagioclase-rich feldspar ore containing admixtures of albite (Na2.00Al2.00Si6.00O16.00:96-900-1633), anorthite (Ca8.00Si16.00Al16.00O64.0:96-900-0362), and quartz (Si3.00O6.00:96-901-2601) by the hydrometallurgical process was examined in methanesulfonic acid media. The experimental parameters during leaching including leachant concentration, pH, reaction temperature, and particle size on the ore dissolution were investigated and correlated with SPSS statistics version 25 using a mixed-effect model. At established conditions (4.0 mol/L MSA, 75 °C, pH = 2, – 75 + 56 µm), 94.50% iron removal efficiency within 120 minutes. The estimated activation energy of 18.65 kJmol−1 supported the proposed mixed control reaction mechanism as the rate-determining step for the ore enrichment.

Insights into catalytic co-pyrolysis of spent coffee grounds and high density polyethylene (HDPE) using acid mine drainage (AMD) treated sludge based catalyst: Analysis of kinetics, mechanism and thermodynamic properties

The present study aims to investigate the catalytic effect of acid mine drainage (AMD) treated sludge based catalyst on the co-pyrolysis of spent coffee grounds and HDPE. The sludge was generated during the treatment of AMD using eggshell and hydrogen peroxide. Theromogravimetric analysis of pyrolysis of spent coffee grounds (SC), HDPE (High density polyethylene), blend of spent coffee grounds and HDPE (SC+HDPE) in the ratio of 1:1, and blended feedstock with sludge derived catalyst (SC+HDPE_AMDC) (1:1 wt. ratio) was conducted at various heating rates of 10 °C/min, 20 °C/min, 30 °C/min and 40 °C/min respectively. Iso-conversional models such as Ozawa Flynn Wall (OFW), Kissinger Akahira Sunose (KAS), Friedman, and Starink were utilized for the determination of activation energy (Ea) of the process. The results showed that using AMD treated sludge based catalyst to the pyrolysis process, enhances its overall efficacy by lowering the activation energy (Ea) (OFW- Ea: 209.11 to 177.14 KJ/mol, KAS-Ea: 208.30 to 173.06 KJ/mol, Friedman- Ea:210.54 to 176.28 KJ/mol, and Starink- Ea:208.60 to 173.44 KJ/mol). Criado's z-master plot (CZMP) method was utilized to analyze the mechanism of the reaction. The pre-exponential factor and thermodynamic parameters were also evaluated. It is concluded that the incorporation of sludge based catalyst (AMDC) lowered enthalpy and randomness of system. Catalytic co-pyrolysis requires less energy, making it more environmental friendly choice for the sustainable processing of biomass and plastics. The present investigation will aid in the design, optimization and scalability.

Adsorption behavior and mechanism of NH2-MIL-101(Cr)@COFs@SA composite adsorbent for tetracycline removal

Herein, we employed a rational approach to develop a hydrogel composite material by encapsulating NH2-MIL-101(Cr)/covalent organic frameworks (COFs) in sodium alginate (SA) to effectively capture of tetracycline (TC). Experimental tests and various characterizations (including Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron spectroscopy (SEM), Brunauer-Emmett-Teller (BET), and X-ray photoelectron spectroscopy (XPS)) confirmed that the NH2-MIL-101(Cr)@COFs@SA composite exhibited a more robust, multilayer pore structure with abundant active functional groups. Under conditions of 298 K and pH = 7, the NH2-MIL-101(Cr)@COFs@SA adsorbent demonstrated remarkable TC adsorption capability, achieving a removal rate of 96.38 % in 120 min and a qmax of 252.6 mg/g at 298 K by Langmuir model. Kinetic analysis indicated that the interaction between TC and NH2-MIL-101(Cr)@COFs@SA follows a pseudo-second-order model, suggesting that chemisoption governs the process. The Langmuir model and thermodynamic analysis suggested that TC adsorption follows a monolayer sorption pattern and is spontaneous and exothermic. Even in the presence of other ions, NH2-MIL-101(Cr)@COFs@SA maintained high efficiency for TC adsorption, demonstrating superior selectivity. NH2-MIL-101(Cr)@COFs@SA demonstrated remarkable recyclability, with only a minimal reduction in the removal efficiency (85.5 % and 142 mg/g) after 10 cycles of adsorption and regeneration. Various analytical techniques, including FTIR spectroscopy, SEM, EDX, XPS, and density functional theory (DFT) calculations of adsorption energy were used to elucidate the TC adsorption mechanisms by NH2-MIL-101(Cr)@COFs@SA. The adsorption process primarily involved π-π stacking, hydrogen bonding, electrostatic interactions, and complexation.

Numerical analysis of catalytic reaction kinetics in methanol steam reformer with variable cross-sectional channel

ABSTRACT Methanol steam reforming (MSR) is a hydrogen production method recognized for its low harmful emissions and high cost-effectiveness. In this study, a three-dimensional numerical model of MSR within channels of variable cross-section. A quantitative relationship between local equilibrium constants and channel structural parameters was established based on the partial pressures of the components. Additionally, the mechanisms by which variable cross-sectional channel structural parameters regulate MSR reaction performance were quantitatively analyzed, considering fluid dynamics, hydrogen production efficiency, and chemical kinetics rates. The results indicate that the kinetic rate of MSR and local equilibrium constants are significantly influenced by the modulation of variable cross-sectional channel structural parameters, with a maximum variation of 50.6%. A positive correlation between methanol conversion rate and the local equilibrium constant of MSR was observed. Utilizing channel structural parameters to enhance MSR led to an 8.75% increase in methanol conversion rate within the same reaction volume. These conclusions may provide theoretical support for regulating volumetric reactions through variable cross-sectional channel structural parameters.

Enhanced Therapeutic Potential of Liposome-Coated Bushen Jianpi Recipe for Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) poses a major healthcare burden globally. Traditional Chinese medicine formula Bushen Jianpi (BSJP) recipe shows inhibitory effects on HCC but suffers from low bioavailability. This study aims to develop a BSJP-loaded liposome (BSJP@Lip) for targeted HCC treatment. BSJP@Lip was prepared using a microfluidic device. Particle characterization included size, morphology, drug loading, encapsulation efficiency, and release kinetics analysis. In vitro cytotoxicity, cellular uptake, apoptosis, and protein expression were evaluated in hepG2, Smmc-7721, and hepa 1-6 hepatic cancer cell lines treated with BSJP@Lip. BSJP@Lip nanoparticles showed a uniform spherical shape with an average size of 50 nm and zeta potential at around -2.24 mV. They significantly inhibited cell viability and induced apoptosis in a dose-dependent manner compared with traditional decoction formulations. Enhanced cellular uptake of BSJP@Lip increased the expression of proinflammatory factors IL-18 and NLRP3. BSJP@Lip nanoparticles were found to be efficiently internalized by hepatic cancer cell lines, resulting in a dose-dependent inhibition of cell viability and induction of apoptosis. This effect was accompanied by the upregulation of IL-18 and NLRP3.

Adsorption characteristics and separation behavior of binder and binderless zeolite LiX Pellets: O2, N2, and CO2

In adsorptive gas separation process design, optimal adsorbent selection acts as a critical factor in process efficiency. This study investigated the adsorption equilibria and kinetics of O2, N2, and CO2 (weak, medium and strong affinity, respectively) and the breakthrough performance of four commercial zeolite LiX pellets (one binderless and three binder zeolite LiX pellets) because the performance of pelletized zeolites becomes different by adding binders and pelletizing methods. The adsorption isotherms at 293–323 K and up to 100 kPa were correlated with the dual-site Langmuir and Sips models. For all adsorbents, the order of adsorption amount and isosteric heat of adsorption was CO2 ≫ N2 > O2. However, differences among the four zeolite pellets were also observed, showing the highest values of the binderless zeolite LiX pellet. Furthermore, the adsorption capacity was 20–25 % smaller for CO2 and 40–50 % smaller of N2 and O2 at 100 kPa compared to pure zeolite LiX powder. According to kinetic analysis using a non-isothermal diffusion model, the adsorption rate of N2 was faster than that of CO2 for all adsorbents, showing the order difference in the low-pressure range. The kinetic difference among the zeolite pellets resulted from the effects of heat of adsorption, heat dissipation, and thermal resistance. The breakthrough performance using N2 and O2 was mainly controlled by the adsorption capacity, showing almost constant breakthrough pattern regardless of the samples. This study suggests that detailed evaluation of pelletized adsorbent is essential before designing adsorptive processes because performance of adsorbent powder would lead to under-design of the process. (255 words)

The g-C3N4/rGO composite for high-performance supercapacitor: Synthesis, characterizations, and time series modeling and predictions

Supercapacitors have gathered significant interest in addressing the increasing need for energy storage devices with high power and energy densities. This study introduces a composite framework designed to enhance supercapacitor performance by leveraging the synergistic effects of g-C3N4/rGO composite. The composite electrode, which combines rGO for high conductivity and g-C3N4 for rapid ion diffusion, demonstrates excellent supercapacitor performance. The synthesized materials were characterized using different analytical tools such as X-ray diffraction, Fourier transform infrared spectroscopy, Brunauer-Emmett-Teller, Scanning and Transmission electron microscope, and X-ray photoelectron spectroscopy. The composite electrode exhibited outstanding performance characteristics, including a specific capacitance of 407.7 F/g, an energy density of 11.4 W h/kg, and a high power density of 186.7 W/kg. Kinetic analysis revealed that the g-C3N4/rGO composite electrode has a dominant diffusive controlled process. The g-C3N4/rGO electrode also demonstrated exceptional durability, maintaining remarkable capacitance retention even after the 5000th charge/discharge cycles. Moreover, the cyclic stability and Coulombic efficiency of the g-C3N4/rGO electrode were modeled and predicted by utilizing the time series analysis technique (Holt-Winters exponential smoothing). Considering the overall results, the g-C3N4/rGO composite electrode has a great potential for energy storage applications.

Highly efficient degradation of ethanol, acetaldehyde, and ethyl acetate removal by bio-trickling filter reactors with various fillers

This study investigates the purification performance of bio-trickling filters (BTFs) using different media to treat ethanol, acetaldehyde, and ethyl acetate in kitchen waste malodorous gases. The media compared included a custom composite medium, pine bark, hollow polyhedral spheres, and ceramic particles. Over 25 days, the composite medium outperformed the traditional media, achieving removal rates of 90.13 % for ethanol, 63.89 % for acetaldehyde, and 82.56 % for ethyl acetate during the biofilm initiation phase, with the others below 60 %. Even under low empty bed residence time and high inlet concentrations, the maximum elimination capacity for ethanol, acetaldehyde, and ethyl acetate was 8.34–14.70 g/m3·h, 9.55–15.06 g/m3·h, and 6.18–10.45 g/m3·h. Kinetic analysis showed the Michaelis-Menten model fit well, indicating enhanced removal potential. High-throughput of 16S rDNA sequencing identified dominant microorganisms like Enterobacteriaceae (13.89 %), Stenotrophomonas (29.23 %), and Acinetobacter (4.09 %) in the composite medium, which thrived even at high pollutant concentrations. Principal component analysis (PCA) demonstrated differences in the microbial composition of the custom composite medium compared to traditional media under varying inlet concentrations and loads. This study provides technical support for the treatment of complex malodorous gas mixtures.

Functional characterization of prenyltransferases involved in de novo synthesis of isoprenoids in the leaf beetle Monolepta hieroglyphica

Prenyltransferases play a pivotal role in the isoprenoid biosynthesis and transfer in insects. In the current study, two classes of prenyltransferases (MhieFPPS1 and MhieFPPS2, MhiePFT-β and MhiePF/GGT-α) were identified in the leaf beetle, Monolepta hieroglyphica. Phylogenetic analysis revealed that MhieFPPS1, MhieFPPS2, MhiePFT-β and MhiePF/GGT-α were clustered in one clade with homologous in insects. Moreover, MhieFPPS2 lacked one aspartate-rich motif SARM. Molecular docking and kinetic analysis indicated that the (E)-GPP displayed higher affinity with MhieFPPS1 compared to DMAPP within the binding pocket containing metal binding sites (MG). The other class of prenyltransferases (MhiePFT-β and MhiePF/GGT-α) lack the aspartate-rich motif. Docking results indicated that binding site of MhiePFT-β involved divalent metal ions (Zn) and bound farnesyl or geranylgeranyl. In vitro, only recombiant MhieFPPS1 could catalyze the formation of (E)-farnesol against different combination of substrates, including IPP/DMAPP and IPP/(E)-GPP, highlighting the importance of SARM for enzyme activities. Kinetic analysis further indicated that MhiePFT-β operated via Zn2+-dependent substrate binding, while MhiePF/GGT-α stabilized the β-subunit during catalytic reaction. These findings contribute to a valuable insight in to understanding of the mechanisms involved in the biosynthesis and delivery of isoprenoid products in beetles.

Promotion of silicon–oxygen control and green sustainable recovery from diamond wire saw silicon powder waste based on the viscous flow mechanism

Diamond wire saw silicon powder (DWSSP) waste is a highly promising secondary resource for recycling high-purity silicon, which is crucial for the sustainable development of the photovoltaic (PV) industry. However, because DWSSP is prone to oxidation, the purity and yield of the recovered silicon are generally low. In this study, the oxidation mechanism of DWSSP in water was systematically investigated, and kinetics analysis and microstructure analysis were conducted to determine the relationship between water diffusion and the growth of the oxide layer. The results indicated that oxidation was determined by the kinetic parameter b in the Reisman model. At T < 328 K and particle size > 1.56 μm, b was less than 1, indicating that the oxidation process was governed by the diffusion of H2O molecules. Through temperature regulation to achieve b < 1, the oxidation was inhibited, which could enhance recovery efficiency. Overall, this study demonstrated the feasibility of inhibiting oxidation by regulating the viscous flow of SiO2 molecules to promote the recycling of silicon resources and support sustainable development.

Cyclodextrin grafted chitosan thermosensitive hydrogel using dual gelling agents: Drug delivery and antibacterial materials

In this paper, three kinds of cyclodextrin-grafted-chitosan (CD-g-CS) were synthesized from chitosan (CS) and β-cyclodextrin (β-CD) with different ratios. And a series of hydrogel with good temperature sensitivity and injectability were prepared by using sodium glycerophosphate (GP) and ammonium hydrogen phosphate (AHP) as dual gelling agents. The gelation formation time of hydrogel was short, and the shortest time was 0.75 min. The FTIR spectrum and 1H-NMR spectrum showed the structure of the compounds and intermolecular interactions. The molecular docking technique probed the encapsulation mechanism of the drug with β-CD. The SEM results showed that the hydrogel had a highly interconnected three-dimensional spatial structure. The swelling ratio of hydrogel was not less than 150 % within 1 h and the degradation rate of hydrogel was not less than 75 % within 14 days. The in vitro drug release results showed that the hydrogel had optimal sustained release effect, and the cumulative release ratio was 58.3 % in 34 h. The release kinetics analysis exhibited that the hydrogel conformed to the Riter-Peppas model. The hemocompatibility test and cytotoxicity test proved that the hydrogel had good biocompatibility and biosafety. The antibacterial experiments showed that the hydrogel could inhibit the biological activity of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Therefore, the CD-g-CS/GP-AHP hydrogel has a broad application prospect in the biological fields of drug delivery and antibacterial materials.