Kinds Of Factors Research Articles

To what extent, which factor has the most significant role contributing to the risk of hypertension?

The existing lifestyle that people have in contemporary society is certainly insufficient to maintain a physical health which can be related to cardiovascular and other diseases, especially like hypertension. While for the inherited or natural genes, they can be mutated or born with the diseased gene fragment that could lead to the potential risks of hypertension, such as congenital hypertension. One of the most significant current discussions in the field of research is which factors are more associated with hypertension. There are two mainstream opinions on this: lifestyle factors and genetic factors. However, there is still some uncertainty about it, such as a lack of data, exceptional examples and especially which kinds of factors really have a dominant role which means they can have a joint role in hypertension. In this essay, the author discusses some specific lifestyle and genetic factors including sleep, diets, exercise, weight, and tooth brushing (minority), and aims at finding detailed information on what play a dominant role leading to the risk of hypertension. Besides, it also illustrates that hypertension is associated with many aspects of factors, not only have combined but also separate roles and some other factors like area, age and gender can also play a role in it.

Effects of washing on structural parameters of medical compression stockings

PurposeThis study aims to evaluate how the structure of medical compression stockings, including three compression levels and five cross-sections from the ankle to the thigh part, will be changed after washing in different conditions and further investigate the effect of the washing parameters on the medical compression stockings.Design/methodology/approachBy washing medical compression stockings in different conditions and measuring the structures (including the density, the girth, the transversal and lengthwise dimension, the weight per unit area and the thickness) of medical compression stockings from the knee to the thigh part.FindingsIt was concluded that the density, the weight per unit and the thickness increase and the girth, the transversal and lengthwise dimension, the weight per unit and the thickness decrease. The change degree of Class one and Class two is greater than Class 3. Moreover, the washing temperature is the most significant factor affecting all the structures of medical compression stockings. Meanwhile, the mechanical actions of the washing machine, like drum speed and washing time, also influence different medical compression stockings structures to different degrees.Research limitations/implicationsThe washing parameter not only includes the temperature and washing cycles but also has other factors, such as the drum speed and washing time. In addition, different kinds of factors will be influenced by each other.Originality/valueThis study can provide consumers advices on the washing of medical compression stockings, and attribute to the optimization of materials and structures to maintain its properties for manufacturers.

Study on The Implementation Intention of Health Protection Behavior of College Students in Epidemic Situation of Infectious Diseases

From the perspective of social cognitive theory, this paper refines and integrates the theory of protective motivation, the theory of planned behavior and the individual and social environment factors in risk research, a comprehensive analytical framework was built to predict the implementation intention of public health behaviors. Through the investigation of the college students during the epidemic of Covid-19, we found that the willingness of the public to carry out health behaviors was influenced by two kinds of factors: external social environment and individual internal conditions. As far as the external environment is concerned, perceived normative influence of “Significant others” and informational influence from mass media can positively promote the implementation intention of health protection behavior. At the same time, media attention can also indirectly affect the public's willingness to carry out health behaviors through the mediating effects of self-efficacy and coping efficacy, respectively. As far as internal factors are concerned, self-efficacy is the most powerful direct factor to predict individuals' health behaviors. The existence of cognitive deficit and optimism bias results in the failure of the predictive power of the element of threat assessment on the willingness to carry out health behaviors, however, perceived severity can have a negative effect on health behavior intention through the mediation of the “Avoidance” concept. The study also found that the emotional response not only positively affected the intention to carry out healthy behaviors independently of the cognitive assessment process, but also played a positive moderating role between media attention and the intention to carry out healthy behaviors, however, improper risk concept may have a blocking effect on the implementation intention of health behavior.

Research on the operation and quality control of small rock hole shotcrete robot

A small rock shotcrete robot is applied in the deep tunnel dynamic disaster physical simulation system in order to simulate the final operation process of the tunnel project. The robot’s spraying operation and control include many kind of factors. In this paper, the main parameters affecting the spraying operation are analyzed by establishing the spraying model and coating growth model. For matching reasonably the spraying parameters, the matching equation of spraying quality and spraying gun parameter model and spraying feed speed has been derived. Based on the matching equation, the spraying gun structure and robot control system are designed, and the spraying distance and spraying gun movement velocity including horizontal and vertical driving have been controlled better. On the basis of theoretical analysis, a small rock hole shotcrete robot prototype has been developed and the spraying experiments have been finished. The experimental results showed that the model and equation established can guided the spraying quality control. With the increase of the injection elevation angle, the length of the long and short axes of the elliptic coating becomes larger, and the average thickness of the coating center is between 2.23 and 2.34 mm, which meets the design index of the injection robot. The rock hole shotcrete robot meet the design requirements.

Using maximum plasma concentration (Cmax) to personalize taxane treatment and reduce toxicity.

Taxanes are a widely used class of anticancer agents that play a vital role in the treatment of a variety of cancers. However, toxicity remains a major concern of using taxane drugs as some toxicities are highly prevalent, they can not only adversely affect patient prognosis but also compromise the overall treatment plan. Among all kinds of factors that associated with taxane toxicity, taxane exposure has been extensively studied, with different pharmacokinetic (PK) parameters being used as toxicity predictors. Compared to other widely used predictors such as the area under the drug plasma concentration curve versus time (AUC) and time above threshold plasma drug concentration, maximum plasma concentration (Cmax) is easier to collect and shows promise for use in clinical practice. In this article, we review the previous research on using Cmax to predict taxane treatment outcomes. While Cmax and toxicity have been extensively studied, research on the relationship between Cmax and efficacy is lacking. Most of the articles find a positive relationship between Cmax and toxicity but several articles have contradictory findings. Future clinical trials are needed to validate the relationship between Cmax and treatment outcome and determine whether Cmax can serve as a useful surrogate endpoint of taxane treatment efficacy.

Patient Characteristics of Secondary Metastatic Bone Disease Due to Primary Lung Cancer in Prof. Dr. IGNG Ngoerah Hospital During 2016-2021: A Descriptive Study

Introduction:The purpose of this study was to compare incidence of pathological fracture due to metastatic bone disease associated with type of lung cancer (LC) according to descriptive data in Prof Dr. dr. IGNG Ngoerah Hospital in 2016-2021 Methods: 21 Patients with lung cancer diagnosed between 2016-2021 in Prof Dr. dr. IGNG Ngoerah hospital. Patient’s range of age were 22-81 years old (mean age: 51 yo). Most location of the fracture happened at femur, humerus region. From the pathological examination, we found the type of the lung cancer were Non-Small Cell Lung Carcinoma (Adenocarcinoma). Results:There were 6 LC patients with MBD was more than 70 years old is affected and patient under than 70 years old is 15 patients. 11 patients were male have bone metastatic bone disease and 10 patient was female. 11 patients have bone metastatic bone disease at femoral, 10 patients consist of the other location group. 12 patients with non-small cell lung carcinoma, and 9 patient without any pathological result. Conclusions:There are several factors like a, gander, active smoker, length of lung cancer, serum marker, race, geography, socioeconomic statue that related to metastatic bone disease. But in this study, we just found 4 kind of factors like age, gender, pathological result and kind of lung cancer. A further study can improve the interpretation of the results. Keywords: Lung cancer, Bone metastatic disease, pathological fracture

Study on the Parameter Influences of Gear Tooth Profile Modification and Transmission Error Analysis

Gear transmission systems are widely used to transfer energy and motion and to guarantee the accuracy of the entire machine system. The modification technique is a common method that improves the gear profile and reduces the transmission error. Based on the parametric model, a modified gear can be established for the evaluation of static and dynamic characteristics. The influences of profile modification parameters and gear parameters are investigated while changing the rules of different kinds of factors. Based on sensitive parameters, a two-stage profile modification curve is proposed to improve the performance of gear pairs. Thus, considering the time-varying mesh stiffness and backlash, a novel, dynamic modified gear model is established to analyze the dynamic performance, such as the dynamic transmission error. Based on the proposed curve, the range and amplitude of the transmission error can be decreased. Additionally, the vibration displacement and noise can be reduced to improve the running characteristics.

Moral Principles: A Challenge for Deniers of Moral Luck

On a common characterization, moral luck occurs when factors beyond agents’ control affect their moral responsibility. The existence of moral luck is widely contested, however. In this paper, I present a new challenge for deniers of moral luck. It seems that some factors beyond agents’ control—such as moral principles about blame- and praiseworthiness—clearly affect moral responsibility. Thus, moral luck deniers face a dialectical burden that has so far gone unnoticed. They must either point to a relevant difference between factors like moral principles and the kind of factors that according to them do not affect moral responsibility or show how they can avoid having to point to such a difference. I argue that no obvious way to meet the challenge presents itself and that it thus amounts to a serious worry for deniers of moral luck.

Uji Aktivitas Anti-Inflamasi Ekstrak Kulit Terong Ungu (Solanum melongena L.) Terhadap Tikus Putih Galur Wistar (Rattus norvegicus) Yang Diinduksi Karagenan

Inflammation is the human body’s defense to prevent tissue damage due to different kinds of factors. The purple eggplant peel (Solanum melongena L.) may have the potential to have anti-inflammatory properties due to containing nasunin, which is a phenolic, flavonoid anthocyanin substance by inhibiting cyclooxygenase pathway. This research was done to prove the anti-inflammatory effect of purple eggplant peel extract in rats. The research method was conducted by true experimental post-test only control-group design. 25 rats were divided into 5 groups with different treatments which are: positive control, negative control, purple eggplant peel extract with a dose of 0,3 mg/gBW, 6 mg/gBW and 0,9 mg/gBW. The data measured was the decrease of edema volume induced by carrageenan at hours-0 1, 2, 3, 4, 5, and 6. Data analysis was performed at the 4th hour using ANOVA and post-hoc LSD tests. The results of the study found that there were significant differences between the negative control group and the positive control group and the entire treatment group. The conclusion of this study was that purple eggplant peel extract had anti-inflammatory activity with the best effectiveness at a dose of 0,9 mg/gBW.

Identification and virus-induced gene silencing (VIGS) analysis of methyltransferase affecting tomato (Solanum lycopersicum) fruit ripening.

Six methyltransferase genes affecting tomato fruit ripening were identified through genome-wide screening, VIGS assay, and expression pattern analysis. The data provide the basis for understanding new mechanisms of methyltransferases. Fruit ripening is a critical stage for the formation of edible quality and seed maturation, which is finely modulated by kinds of factors, including genetic regulators, hormones, external signals, etc. Methyltransferases (MTases), important genetic regulators, play vital roles in plant development through epigenetic regulation, post-translational modification, or other mechanisms. However, the regulatory functions of numerous MTases except DNA methylation in fruit ripening remain limited so far. Here, six MTases, which act on different types of substrates, were identified to affect tomato fruit ripening. First, 35 MTase genes with relatively high expression at breaker (Br) stage of tomato fruit were screened from the tomato MTase gene database encompassing 421 genes totally. Thereafter, six MTase genes were identified as potential regulators of fruit ripening via virus-induced gene silencing (VIGS), including four genes with a positive regulatory role and two genes with a negative regulatory role, respectively. The expression of these six MTase genes exhibited diverse patterns during the fruit ripening process, and responded to various external ripening-related factors, including ethylene, 1-methylcyclopropene (1-MCP), temperature, and light exposure. These results help to further elaborate the biological mechanisms of MTase genes in tomato fruit ripening and enrich the understanding of the regulatory mechanisms of fruit ripening involving MTases, despite of DNA MTases.

Proactive Relocation Decision-Making in a Multinational Manufacturing Network

Recent years have been demanding for manufacturing companies with a global footprint – the constant need to evaluate and re-evaluate manufacturing networks and sourcing due to ongoing crises e.g., coronavirus shutdowns, changing customs tariffs, economic sanctions, inflation, availability issues, and war. A decade ago, everything was more stable in corporate manufacturing networks, and capacity allocation was merely based on cost consideration, competencies, and demand of different regions. Due to the changes mentioned, developed nation companies have started reshoring manufacturing operations increasingly back to developed countries; this is mostly due to hedging uncertainty and assuring availability and deliveries. This research analyses one steel industry case study of a corporate manufacturing network and shows what kind of factors their location decisions are based on in the current environment. The case also illustrates the ongoing process of manufacturing location and relocation with make or buy consideration. The process is implemented in stages, and if triggers are reached, the assessment is completed in a more comprehensive manner. In the end, we propose Information Technology (IT) advances and solutions for this environment, where the assessment period could have better responsivity, quality, and shorter lead time. Furthermore, we propose further changes and research on what decision factors should be included in the proactive relocation decision-making process.

Exploring the joint effects of stressors and resources on student engagement in teacher education: a French study

ABSTRACT Evidence points to the existence of several stressors and resources that contribute to students’ engagement in teacher education, but more research is needed to integrate both kinds of factors within a common analytical framework. This study proposes such integration by testing a stress process model, in which stressors and resources combine with each other to predict preservice teachers’ engagement in their training. Using data from a sample of French preservice teachers (N = 340 French preservice teachers), results from structural equation models of student engagement (45.9% of variance explained) provide evidence for moderation and mediation effects characteristic of stress processes, notably between academic stressors (study workload, poor quality courses), academic resources (college self-efficacy, support from teacher educators) and vocational resources (intrinsic career motive). Implications are drawn on ways to counteract the negative impact of stressors in teacher education, and on ways to foster more integrative research on the stress processes that undergird preservice teachers’ engagement processes.

Biomarkers of Autoimmune Chronic Spontaneous Urticaria.

Chronic spontaneous urticaria and chronic inducible urticaria (CSU/CindU) are caused by mast cell and basophil activation leading to degranulation and the release of histamine and several other mediators. Three kinds of factors can trigger mast cells in CSU: (1) activation of stimulating receptor(s) on the mast cell membrane, (2) upregulation of certain receptor(s), and (3) intracellular dysregulation in signaling with overexpression of the spleen tyrosine kinase (SYK) or reduced activation of the inhibitory Src homology 2 (SH2)-containing inositol phosphatases (SHIP)-related pathways. In CSU, two major endotypes exist based on the primary receptor activating mechanism: type I hypersensitivity (IgE-mediated, directed against auto-allergens) and type IIb (autoimmune, via IgG autoantibodies directed against IgE or the IgE-receptor). Their treatment responses vary. We discuss in vitro and in vivo biomarkers. Patients with auto-allergic CSU have clinical characteristics that can distinguish them partly from those with autoimmune CSU. Most importantly, their disease generally presents a less aggressive course, a better response to second generation (up-dosed) antihistamines and a good response to omalizumab, if necessary. Meanwhile, autoimmune CSU/CindU patients fare less well and often need immunosuppressive drugs. Biomarkers that might help endotype CSU/CindU patients and select the most appropriate treatment, dose, and duration, e.g., for autoallergic CSU, high total IgE and IgE against auto-allergens; for autoimmune CSU, low IgE, basopenia, and IgG against autoantigens like thyroid peroxidase and a positive autologous serum skin test (but sometimes also positive in autoallergy). Some biomarkers are easily accessible but of low specificity; others are highly specific but more futuristic.

The Conflicts and Awakeness of Self-awareness -- On the Character of Sun Shaoping in the Ordinary World

In the decades since The Ordinary World came out, scholars in the literary world have never stopped exploring it, because it is a masterpiece that has inspired generations of young people to struggle with difficulties in their life. Firstly, this paper selects the character of Sun Shaoping in the book as an example. Then, on the basis of author Lu Yao's background and several characters in the book who are closely related to Sun Shaoping, the paper analysed the reasons for the creation of character to deeply investigate what kind of factors and environments contribute to the formation of this self-awareness. Finally, all the efforts is to reveal the conflicts and self-awareness of character’s inner world.

Possibilities of battery-free AACloth for augmentative and alternative communication: views of parents of children with cerebral palsy

Cerebral palsy (CP) is a neurological disorder that primarily affects body movement, muscle coordination, and muscle tone. Non-progressive brain injury or abnormal brain development that occurs while the child’s brain is under development causes CP. It is estimated that 40–85% of children with CP have communication difficulties. Children with communication difficulties can benefit from augmentative and alternative communication (AAC). However, studies have shown that several challenges in using AAC exist. Developing existing AAC methods and creating new AAC solutions are important to enable everyone to communicate and express themselves without barriers. This qualitative study aims to investigate how parents of children with CP would use a wireless and battery-free, passive radio-frequency identification (RFID)-based e-textile—AACloth—as an AAC solution. The research was conducted via an online survey. Parents with a child under 15 with CP and communication difficulties were included. Parents were recruited by distributing the survey invitation via the Finnish CP Association’s monthly newsletter, Facebook page, and social media groups. Nine parents participated. Based on parents’ views, the AACloth could solve some of the challenges associated with existing AAC methods. This research provides perspectives on what kinds of factors should be considered when developing existing and new AAC aids.

Factors Affecting Share Prices of Finance Companies in Sri Lanka

The price of a share is influenced by a variety of internal and external factors. Internal factors are those dependent on the company, such as return on equity, and earnings per share. The external influences include raw material pricing, economic trends, inflation, investor confidence, interest rate, exchange rate, and other factors that are beyond the firm's control. Both kind of factors may influence the investor’s future expectations and risk-taking ability, and as a result that they take their investment decisions. This study aimed to examine the factors affecting share prices in finance companies in Sri Lanka for the period of five years, from 2017 to 2022. For that purpose, researchers selected the independent variable as the share price, while the dependent variables are earnings per share (EPS), return on equity (ROE), interest rate, inflation, and exchange rate. The researchers collected data from the CSE data library, Company annual reports, and Central Bank Reports. The STATA was used to analyze the data in this study. Descriptive Statistics, Correlation Analysis, Regression Analysis were performed as analytical tools. The findings highlighted that EPS and inflation positively impact raw material pricing, while ROE, interest rate, and exchange rate showed a negative impact. But only EPS shows a significant impact on the raw material pricing. This study suggested to take at least 10 years duration for data collection and consider more internal and external factors.

Study on the determinants of health professionals’ performance on diabetes management care in China

BackgroundAs the direct providers of diabetes management care in primary health care facilities (PHFs) in China, health professionals’ performance on management care of diabetes determines the quality of services and patients’ outcomes. This study aims to analyze the key determinants of health professionals’ performance on diabetes management care in PHFs in China.MethodsWe conducted a cross-sectional study in 72 PHFs in 6 cities that piloted the contracted family doctor service (CFDS). Self-developed questionnaire was used to measure three kinds of factors (capacity, motivation and opportunity) potentially influencing the performance of health professionals. The performance of diabetes management care in the study was measured as whether health professionals delivered 7 service items required by the National Basic Public Health Service Guideline with a total of 7 points and was divided into three grades of good, medium and bad. The questionnaire is self-administered by all the health professionals involved in the study with the number of 434. The Chi-square tests were used to compare differences of performance on diabetes management care among health professionals with different characteristics. The ordinal logistic regression was used to analyze the determinants on the performance of diabetes management care.ResultsHealth professionals who got higher score on diabetes knowledge test had odds of better performance on diabetes management care (OR = 1.529, P < 0.001). health professionals with higher degree of self-reported satisfaction on training (OR = 1.224, P < 0.05) and perception of decreasing workload (OR = 3.336, P < 0.01) had odds of better performance on diabetes management care. While health professionals with negative feeling on information system support had odds of worse performance on diabetes management care (OR = 0.664, P < 0.01).ConclusionsAttention should be paid to the training of health professionals’ knowledge on diabetes management capacity. Furthermore, measures to improve training for health professionals could satisfying their needs for self-growth and improve the motivation of health professionals. The information system supporting management care should be improved continuously to improve the health professionals’ working opportunities and decrease the workload.

Multifaceted Role of Nanomaterials in Modulating In Vitro Seed Germination, Plant Morphogenesis, Metabolism and Genetic Engineering.

The agricultural practices of breeding, farm management and cultivation have improved production, to a great extent, in order to meet the food demands of a growing population. However, the newer challenges of climate change, global warming, and nutritional quality improvement will have to be addressed under a new scenario. Plant biotechnology has emerged as a reliable tool for enhancing crop yields by protecting plants against insect pests and metabolic engineering through the addition of new genes and, to some extent, nutritional quality improvement. Plant tissue culture techniques have provided ways for the accelerated clonal multiplication of selected varieties with the enhanced production of value-added plant products to increase modern agriculture. The in vitro propagation method has appeared as a pre-eminent approach for the escalated production of healthy plants in relatively shorter durations, also circumventing seasonal effects. However, there are various kinds of factors that directly or indirectly affect the efficiency of in vitro regeneration like the concentration and combination of growth regulators, variety/genotype of the mother plant, explant type, age of seedlings and other nutritional factors, and elicitors. Nanotechnology as one of the latest and most advanced approaches in the material sciences, and can be considered to be very promising for the improvement of crop production. Nanomaterials have various kinds of properties because of their small size, such as an enhanced contact surface area, increased reactivity, stability, chemical composition, etc., which can be employed in plant sciences to alter the potential and performance of plants to improve tissue culture practices. Implementing nanomaterials with in vitro production procedures has been demonstrated to increase the shoot multiplication potential, stress adaptation and yield of plant-based products. However, nanotoxicity and biosafety issues are limitations, but there is evidence that implies the promotion and further exploration of nanoparticles in agriculture production. The incorporation of properly designed nanoparticles with tissue culture programs in a controlled manner can be assumed as a new pathway for sustainable agriculture development. The present review enlists different studies in which treatment with various nanoparticles influenced the growth and biochemical responses of seed germination, as well as the in vitro morphogenesis of many crop species. In addition, many studies suggest that nanoparticles can be useful as elicitors for elevating levels of important secondary metabolites in in vitro cultures. Recent advancements in this field also depict the suitability of nanoparticles as a promising carrier for gene transfer, which show better efficiency than traditional Agrobacterium-mediated delivery. This review comprehensively highlights different in vitro studies that will aid in identifying research gaps and provide future directions for unexplored areas of research in important crop species.

Towards an eco-welfare state: Enabling factors for transformative eco-social initiatives

In eco-welfare states, welfare provision must operate within planetary boundaries, entailing societal transformations and significant emission reductions. This article contributes to the research on sustainable welfare and eco-social policies by examining transformative and integrative eco-social initiatives that aim to reduce environmental impacts while also ensuring that public actors have the capacities to reach legally binding social outcomes and enhance social inclusion. Theoretically, we combine welfare state transformation research with the concepts of social-ecological systems, provisioning systems and transformative capacity. Our empirical cases in Finland include public actors promoting sustainable public procurement, a network of carbon-neutral municipalities, sustainable lifestyles accelerators at the household level, and carbon footprint calculators as a potential free-to-use technique that supports widespread carbon reductions. We apply a qualitative research design to investigate what kinds of factors are crucial in enhancing the transformative capacity of provisioning systems and how various factors in practice enable the eco-social initiatives to support the transformation towards an eco-welfare state. Our findings identify key enabling factors for transformative capacity: social networks, collaboration and participation; knowledge, learning and monitoring; shared policy frameworks and visions; and financial resources. These factors are interrelated and can be brought to bear in no particular sequence. The results offer valuable insights into how welfare state characteristics with democratically governed public actors may facilitate transformation.

Analysis of Commander Authorities to Punish subordinate in the Implementation of Disciplinary Legal Sanctions Against Soldiers Who Violate Discipline Regulations

Background. The application of legal sanctions for soldier discipline within the Indonesian Army is an attempt to minimize the existence of violations that occur among Indonesian Army soldiers. In this case, every commander has the authority to take disciplinary action against every subordinate who violates the law on soldier discipline and immediately reports it to the Ankum concerned.&#x0D; Purpose. This study aims to determine the function of Ankum's (Atasan yang berhak menghukum – commander with the right to punish) authority in the application of disciplinary sanctions for TNI soldiers. To find out the effectiveness of the application of disciplinary legal sanctions to prevent the recurrence of disciplinary law violations of TNI soldiers.&#x0D; Method. This study uses normative research methods, by collecting primary data in the form of interviews with Ankum. And secondary data in the form of laws, books, journals, and related scientific articles.&#x0D; Results. The results of this study, namely Ankum's authority in applying disciplinary sanctions to TNI soldiers by imposing penalties on TNI soldiers who commit disciplinary violations and the behavior of soldier disciplinary violations are influenced by 2 (two) kinds of factors, namely internal and external factors. Ankum must implement effective leadership.&#x0D; Conclusion. The application of legal sanctions for soldier discipline within the Indonesian Army is an attempt to minimize the existence of violations that occur among Indonesian Army Force. In this case, every commander has the authority to take disciplinary action against every subordinate who violates the law on soldier discipline and immediately reports it to the Ankum concerned..