Kidney Failure Patients Research Articles

Causes of kidney failure among patients undergoing maintenance hemodialysis in Somalia: a multi-center study

BackgroundKidney failure is one of the leading causes of morbidity and mortality worldwide. The incidence of kidney failure in Somalia has been increasing in recent years. There is no data available on the causes of chronic kidney disease (CKD) leading to kidney failure in Somalia.MethodsThis is a multicentre, descriptive cross-sectional study designed to determine the aetiology of kidney failure among patients receiving haemodialysis in four major demographic areas of Somalia. The study was conducted over a one-year period, from June 2021 to June 2022. Participants were eligible for inclusion if they had been diagnosed with kidney failure, were on regular haemodialysis, and were over 18 years of age.ResultsA total of 127 patients were evaluated, 84 (66.1%) were males and 43 (33.9%) were female. The mean age of kidney failure patients was 49.3 ± 12.2 years. They originated from various regions, 5.6% from the south, 29.9% from the north-eastern, and 64.5% from the northwest. The mean duration of haemodialysis was 4.4 ± 2.2 years. The most common cause of kidney failure in our study was hypertension (33.1%), followed by diabetes mellitus (27.6%), uncertain aetiology (24.4%), glomerulonephritis (7.1%), obstructive uropathy (3.8%), renovascular hypertension (1.6%), neurogenic bladder, polycystic kidney disease, congenital and hereditary diseases (0.8%).ConclusionsOur study showed the leading cause of kidney failure among maintenance haemodialysis patients was hypertension, followed by diabetes mellitus. To reduce the burden of kidney failure in Somalia, primary prevention of hypertension and diabetes and early detection and prompt management of chronic kidney disease (CKD) in high-risk populations should be a fundamental focus.

MONITORING DAN EVALUASI PENGGUNAAN OBAT PADA PASIEN TERAPI GAGAL GINJAL KRONIK DI RUMAH SAKIT UMUM SEMBIRING DELI TUA

Chronic kidney failure is an interventional disease, which means that the patient only maintains existing kidney function and this disease is irreversible, meaning it cannot return to normal. Thus, chronic kidney failure is closely related to a rational treatment process and a healthy lifestyle. Therefore, it is necessary to study patterns of monitoring and evaluating drug use in patients with chronic kidney failure therapy at Sembiring Deli Tua General Hospital. This study aims to determine the lifestyle of second chronic kidney failure patients to determine the effect of chronic kidney failure patients' lifestyle on further improvement of kidney function. To determine rational drug use at Sembiring Deli Tua General Hospital using four aspects, namely right drug, right patient, right indication and exact last dose to see and know the distribution of chronic kidney failure to patient characteristics in the form of age, sex, disease complications, complaints and stage of chronic kidney failure patients at Sembiring General Hospital. Lifestyle monitoring was carried out in April-May 2023 in the hemodialysis room using a sample questionnaire that was taken as many as 30 respondents using a descriptive method. Then, an evaluation of drug use was taken from the medical record data of chronic kidney failure patients from September to December 2022 using a retrospective method. A sample of 30 patients according to the study inclusion criteria. The lifestyle of chronic kidney failure patients is in accordance with the provisions, and there is a relationship between the lifestyle of chronic kidney failure on the improvement of kidney function indicators are blood pressure, hemoglobin, urea and creatinine. Evaluation data on drug use in patients with chronic kidney failure in terms of four aspects including (100% right patient), (43.33% right drug), (83.33 place of indication), (80% right dose). patient characteristics in the form of age at most 46-55 years, the dominant sex is Male, complications of diseases namely hypertension then diabetes sequence When COPD, the most common complaint is lower abdominal pain, and the most common stage of chronic kidney failure patients is stage 3 at Sembiring General Hospital.

The impact of anxiety and depression on the quality of life of hemodialysis patients in a sample from Somalia

ObjectiveThe main objective of the present study was to determine the quality of life (QoL), depression, and anxiety levels in kidney failure patients undergoing hemodialysis (HD) treatment and examine the impact of depression and anxiety on the QoL of these patients in a sample from Somalia.MethodsA sample of 200 patients with kidney failure who were undergoing HD treatment approximately two to three times a week was included. All participants were administered a sociodemographic data form, the Patient Health Questionnaire-9 (PHQ-9), the Hospital Anxiety and Depression Scale (HADS), and the World Health Organization Quality of Life (WHO-QOL-BREF). Subjects on HD for less than 3 months prior to the study date were excluded.ResultsOf the kidney failure patients, 200 patients, aged 18–86 years (median: 50.0; IQR: 25.0), consented and participated in the study. 58.5% of the participants were men; 64% had a kidney failure duration of 1–5 years, and 52.6% had a HD duration of 1–5 years. Mild symptoms of depression were found in 48%, while moderate-to-severe depressive symptoms were found in 13.5% of HD patients. Depression and anxiety were found to be significantly correlated with overall QoL, physical health, psychological health, social relationships, and environmental well-being. There were similar predictors of overall QoL, physical health, psychological well-being, social relationships, and environmental well-being relating to socio-demographic factors such as age, gender, family income, anxiety, and depression.ConclusionsThis study emphasizes the important role that anxiety, depression, and family income have in HD patients' QoL in Somalia. It highlights the significance of regular emotional assessment and efficient management in order to increase patient satisfaction. Future studies with larger samples are necessary for more accurate statistical analysis. To optimize patient care, a multidisciplinary healthcare team is recommended.

Risk of kidney failure in patients with systemic sclerosis: a nationwide population-based study

ObjectiveData from a decade ago have shown that patients with systemic sclerosis (SSc) have a higher risk of kidney failure than the general population. However, as the incidence of kidney...

Risk Factors for Progression to Kidney Failure in Patients with CKD Stages 3B and 4 in a Singaporean Cohort

Risk Factors for Progression to Kidney Failure in Patients with CKD Stages 3B and 4 in a Singaporean Cohort

Association Between Changes in Urinary Albumin and Protein Excretion and Risk of Kidney Failure in Patients with CKD: The CKD-JAC Study

Association Between Changes in Urinary Albumin and Protein Excretion and Risk of Kidney Failure in Patients with CKD: The CKD-JAC Study

Experiencing Discrimination Reduced the Effectiveness of the TALK Intervention on Kidney Failure Patients

Experiencing Discrimination Reduced the Effectiveness of the TALK Intervention on Kidney Failure Patients

OVERCOMING ANXIETY CHRONIC KIDNEY FAILURE PATIENTS WITH SPIRITUAL MINDFULNESS INTERVENTION: A CASE STUDY

ABSTRACT Chronic kidney failure sufferers experience many changes in their lives, including changes in diet management, exercise, control of blood sugar, urea, creatinine and kidney function replacement therapy, so they are prone to experiencing anxiety. The aim of this case study is to carry out nursing care to overcome anxiety problems in kidney failure patients with spiritual mindfulness intervention in the Inpatient Room of the Surabaya A.Yani Islamic Hospital. This type of research is a qualitative method with a case study approach. The subjects used were 1 patient with chronic kidney failure who was being treated at the Surabaya A. Yani Islamic Hospital with anxiety problems. Nursing care includes: assessment, determining a diagnosis, making interventions, implementation and evaluation. The implementation, which was carried out to overcome anxiety with spiritual mindfulness interventions, was carried out for 3 days (2 times a day for 10-15 minutes). The results of the spiritual mindfulness intervention after nursing actions were carried out for 3 days, the nursing problem of anxiety was resolved. The patient experienced a change from initially the patient having an anxiety score of 80 (severe anxiety) to 40 (not anxious). Spiritual mindfulness intervention is effective in reducing anxiety so it can be used as an alternative to reduce anxiety in patients with chronic kidney failure.

Dukungan Keluarga Terhadap Kualitas Hidup Pasien Hemodialisa di RS PKU Muhammadiyah Yogyakarta

<p><em>Patients with chronic renal failure undergoing hemodialysis experience decreased kidney function to remove metabolic waste products in order to maintain fluid and electrolyte balance in the body. Various problems faced by patients are risk of reducing their quality of life. Support from family becomes one of the patient's sources of strength to survive. This study aims to determine the relationship between family support and quality of life of chronic kidney failure patients undergoing hemodialysis at PKU Muhammadiyah Hospital Yogyakarta. This study used a correlational research design with a cross sectional approach. Respondents amounted to 125 patients who were taken by total sampling technique. The results showed that the p-value = 0.000 or p <0.05 with a correlation coefficient (r) = 0.724, so it can be said that there is a very strong relationship between family support and the quality of life of chronic kidney failure patients undergoing hemodialysis at PKU Muhammadiyah Hospital Yogyakarta. From the results of the study, it can be concluded that family support is very strongly correlated with the quality of life of hemodialysis patients. The relationship of other variables such as age, gender, education, occupation, income, duration of hemodialysis, and frequency of hemodialysis on the quality of life of patients with chronic kidney failure requires analysis for further studies.</em></p>

Gambaran Kecemasan Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa di Rumah Sakit Santa Elisabeth Medan Tahun 2023

Background: Chronic renal failure is the presence of progressive kidney damage in the human body characterized by uremia (urea in other wastes circulating in the blood and its complications. Hemodialysis is a high-tech substitute for removing metabolic waste from human blood circulation such as water, sodium, potassium, hydrogen, urea, creatinine, uric acid, and other substances through a semi-membrane Permeable as a separator of blood and dialysate fluid in artificial kidneys where diffusion, osmosis and ultra filtration processes occur. Proses hemodialysis 1-3 times a week and each time takes 2-5 hours, this activity will continue 3-4 hours per therapy. Anxiety in hemodialysis patients arises because during the hemodialysis process they see tubes that are fed by blood entering the body, they also have to pay costs when undergoing hemodialysis, and uncertainty about recovery. Objective: To find out the anxiety picture of chronic kidney failure patients undergoing hemodialysis at Santa Elisabeth Medan Hospital 2023. Methods: To find out the anxiety picture of chronic kidney failure patients undergoing hemodialysis at Santa Elisabeth Medan Hospital 2023. Method: This study is a descriptive research. Sampling using Total Sampling technique amounting to 40 respondents. The research instrument uses Zung Self Rating Scale (ZSAS) questionnaire. Results: The results of this study found that the anxiety of chronic kidney failure patients undergoing hemodialysis at the Santa Elisabeth Hospital in Medan in 2023 mostly experienced mild anxiety as much as 50.0%, moderate anxiety as much as 40.0% and severe anxiety as much as 7.5% and panic as much as 2.5%. Conclusion: This researcher illustrates that the anxiety level of patients with chronic kidney failure undergoing hemodialysis is influenced by characteristics such as age, type of health, and education.

Analysis of Energy and Protein Intake with Nutritional Status of Chronic Kidney Failure Patients with Hemodialysis at Harapan and Doa Regional Hospital, Bengkulu City

Background:Chronic kidney disease is a global public health priority that continues to grow and is associated with high morbidity rates and is the third fastest growing cause of death in the world and the fifth leading cause of death. Malnutrition often occurs in end-stage renal disease patients undergoing hemodialysis (HD). Malnutrition is caused by catabolic events during the hemodialysis process. Objective: The aim of the study was to analyze energy intake, protein and nutritional status of chronic kidney failure patients on hemodialysis at Harapan and Doa Regional Hospital, Bengkulu City. Materials/Methods: Explanatory research type, with a cross sectional approach. The study population was all chronic kidney failure sufferers who underwent hemodialysis at Harapan and Doa Hospital, Bengkulu City in June-July 2023. Data were collected by interviews and anthropometric measurements, 3x24 hour recall forms and SGA forms and from patient medical records. Data processing was carried out using univariate tests. Result:This study shows that 98% of respondents' energy intake before hemodialysis had insufficient energy intake (< 80%) and 2% had sufficient energy intake (80), protein intake before hemodialysis 92% protein intake is less (< 80%) during hemodialysis and after hemodialysis 85% with less protein intake (< 80%), nutritional status of chronic kidney failure patients with hemodialysis good nutritional status (SGA score A), namely (54%) lack of protein intake, poor/moderate nutritional status (SGA B score), namely (43%), poor nutritional status (SGA C score), namely (3%). Conclusion:The conclusion of this study is that energy intake, protein and nutritional status in chronic kidney failure patients on hemodialysis are still lacking. Therefore, increasing intake needs to be done by paying attention to the patient's nutritional status

Segmental bioimpedance in pregnant end stage renal failure patient for dry weight titration and volume management (case report)

BackgroundVolume assessment, dry weight titration, and blood pressure control in pregnant kidney failure patients are often challenging, with physiological fluid accumulation in the trunk and lower limbs and an increased risk of preeclampsia. We used segmental bioimpedance in the volume management of our kidney failure patient on haemodialysis.Case presentationWe report a case of a female patient on maintenance haemodiafiltration with no residual kidney function for whom we used segmental bioimpedance to guide dry weight adjustment. At different gestational periods, we targeted a different extracellular to total body water ratio according to body segments. This allowed us to support her high-risk pregnancy, identify her as probably developing preeclampsia and trigger a plan for closer monitoring and delivery during the third trimester when she had rapid weight gain.ConclusionSegmental bioimpedance is a practical, simple, and non-invasive test that can be performed at the dialysis unit and is useful as an adjunct decision-making tool in the management of pregnant dialysis patients.

Nursing Care for Chronic Kidney Failure Patients with Fluid Management Intervention at the Dr. Regional General Hospital. Djarart Prawiaranegara Serang

Problems often experienced by Chronic Kidney Failure patients undergoing hemodialysis therapy are related to excess fluid intake in the body. Patients with chronic renal failure who do not comply with fluid intake restrictions will experience fluid accumulation, causing pulmonary edema and left ventricular hypertrophy. The buildup of fluid in the body causes the heart and lungs to function hard, resulting in patients becoming tired and short of breath. while intake that is too low results in dehydration, hypotension, and impaired kidney function. Failed Diseases. Monitoring fluid intake and output in patients has proven to be effective in dealing with excess fluid volume. It is hoped that using non-pharmacological therapy is one method for patients with chronic kidney failure with fluid balance and electrolytes in fluid management interventions. The research results were obtained after fluid management was carried out to reduce fluid and electrolyte balance in patients with chronic renal failure, blood pressure improved, edema was reduced, skin turgor was good, there were no additional breath sounds, patients were able to understand the importance of limiting fluid and sodium intake. , and be able to measure and record food intake and urine output independently.

Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing.

Chronic kidney disease (CKD) is an age-related disease that displays multiple features of accelerated ageing. It is currently unclear whether the two treatment options for end-stage kidney disease (dialysis and kidney transplantation [KT]) ameliorate the accelerated uremic ageing process. Data on clinical variables and blood DNA methylation (DNAm) from CKD stage G3-G5 patients were used to estimate biological age based on blood biomarkers (phenotypic age [PA], n=333), skin autofluorescence (SAF age, n=199) and DNAm (Horvath, Hannum and PhenoAge clocks, n=47). In the DNAm cohort, we also measured the change in biological age 1 year after the KT or initiation of dialysis. Healthy subjects recruited from the general population were included as controls. All three DNAm clocks indicated an increased biological age in CKD G5. However, PA and SAF age tended to produce implausibly large estimates of biological age in CKD G5. By contrast, DNAm age was 4.9 years (p=0.005) higher in the transplantation group and 5.9 years (p=0.001) higher in the dialysis group compared to controls. This age acceleration was significantly reduced 1 year after KT, but not after 1 year of dialysis. Kidney failure patients displayed an increased biological age as estimated by DNAm clocks compared to population-based controls. Our results suggest that KT, but not dialysis, partially reduces the age acceleration.

Faktor-Faktor Yang Berhubungan Dengan Kepatuhan Pembatasan Cairan Pada Pasien Gagal Ginjal Kronis Yang Menjalani Hemodialisa Di Ruang Hemodialisa RSUD Raja Ahmad Tabib Provinsi Kepri

WHO (World Health Organization) data for 2020 is one of the main health problems in the world, globally around 1 in 10 of the world's population is identified as chronic kidney disease. The aim of this research is to determine the factors associated with compliance with fluid restrictions in chronic kidney failure patients undergoing hemodialysis in the hemodialysis room at Raja Ahmad Tabib Hospital, Riau Islands Province. This type of research is quantitative descriptive with a cross sectional approach. The sample in this study consisted of 48 people. Data collection methods and tools use questionnaires. The conclusion from the data analysis is that there is a significant relationship between family support and compliance with fluid restrictions in chronic kidney failure patients undergoing hemodialysis with a significant value of 0.007<0.05, there is a relationship between staff support and compliance with fluid restrictions with a sig p value of 0.000<0, 05 and there is a relationship between the length of HD and compliance with fluid restrictions with a sig p value of 0.000 <0.05 in the Chi Square test. Suggestion: it is hoped that this research can increase knowledge regarding compliance with fluid restrictions in chronic kidney failure patients undergoing hemodialysis, so that respondents can minimize the occurrence of complications due to excess fluid.

Hubungan Health Locus Of Control Dengan Kualitas Hidup Pada Pasien Penyakit Ginjal Kronis Yang Menjalani Hemodialisis Di RSUD Raja Ahmad Thabib

Kidney failure is a serious public health problem, the impact of an unhealthy lifestyle, and the costs of treatment and care are quite expensive. The lives of patients with chronic renal failure are regulated and adapted to the changes caused by the nature of the disease and the methods of its treatment. Hemodialysis carried out by patients can maintain survival and at the same time change the patient's lifestyle. To find out if someone controls compliance, you can use health locus of control. This study aims to determine the relationship between health locus of control and quality of life in chronic kidney disease patients undergoing hemodialysis at Raja Ahmad Thabib Regional Hospital. The design of this research is descriptive quantitative with a cross sectional approach. The results show that there is a relationship between health locus of control and quality of life in chronic kidney disease patients undergoing hemodialysis at Raja Ahmad Thabib Regional Hospital, with a p value of 0.006≤0.05. It is hoped that health workers will carry out treatment for chronic kidney failure patients by providing education, motivation and moral support to patients who are undergoing treatment and providing psychological counseling for patients who need it.

A Quality Analysis of Donor Nephrectomy-Related Information on YouTube; Education or Misinformation?

There currently remains an urgent need to increase living kidney donation to help mitigate the high demand for waitlisted kidney failure patients. Potential kidney donors can readily access social media, particularly YouTube, to gain basic knowledge about live donor nephrectomy surgical procedures. YouTube is an open-source platform where anyone can upload videos about any topic without peer review or quality control and is frequently used for disseminating health education. This study aims to assess the quality and accuracy of information regarding live donor nephrectomy on YouTube. A YouTube search was performed using the keywords "donor nephrectomy" and "kidney transplant." A total of 57 videos were assessed for eligibility criteria. Two validated tools for evaluating health information, the DISCERN and The Patient Education Materials Assessment Tool for Audiovisual Materials tools, were used to assess YouTube video information quality, understandability, and actionability. A total of 53 of 57 screened videos were included in this study, with 4 videos being excluded for not being primarily in the English language. The mean (SD) DISCERN score was 23.3 (±8.3), and the mean (SD) The Patient Education Materials Assessment Tool for Audiovisual Materials Understandability and Actionability scores of 41.7% (±17.5) and 8.2% (±22.9%), respectively. Although videos were generally relevant in content to donor nephrectomy, videos lacked quality information and actionable items. Information on living donor nephrectomies is prevalent on YouTube. Our assessment using quality measures of selected videos illustrates substantial misinformation on living donor nephrectomies. YouTube has the potential to be a source of reliable and accurate information on living donor nephrectomies and donations.

Implementasi Self Healing Untuk Mengatasi Kecemasan pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisa di Rs Permata Medika Semarang

HD room nurses are health workers who play an active role in managing nursing care starting from assessment, both physically and psychologically. Determine nursing problems that arise in patients based on the results of the assessment, determine interventions, carry out implementation according to the plans that have been determined and evaluate the actions / implementations that have been carried out. In accordance with the problems experienced by these partners, the efforts made include implementing self-healing in chronic kidney failure patients undergoing hemodialysis therapy who experience anxiety. The specific target of this PKM activity is to teach self-healing therapy in the prevention and treatment of anxiety, especially in chronic kidney failure patients undergoing hemodialysis therapy at Permata Medika Hospital, Semarang. Teaching chronic kidney failure patients undergoing hemodialysis therapy how to do self-healing. Demonstration of self-healing therapy according to SOP. The result of this service activity is that the level of knowledge of chronic kidney failure patients undergoing hemodialysis therapy at Permata Medika Hospital in Semarang increases after being given material on self-healing management with five finger hypnosis, besides that the patient is able to carry out a simulation on how to reduce anxiety with five finger hypnosis.

Relationship Between Standardized Measures of Chronic Kidney Disease-associated Pruritus Intensity and Health-related Quality of Life Measured with the EQ-5D Questionnaire: A Mapping Study.

Chronic kidney disease-associated pruritus is linked with decreased health-related quality of life assessed using disease-specific instruments. The extent to which worsening pruritus reduces generic quality of life assessed using the EQ-5D instrument is unknown. Prevalent kidney failure patients receiving in-centre haemodialysis from 5 centres completed the EQ-5D-5L quality of life measure, worst Itching Intensity Numerical Rating Scale and 5-D itch pruritus instruments. Latent class models were used to identify clusters of patients with similarly affected body parts, and mixture models were used to map the pruritus measures to the EQ-5D. Data on 487 respondents were obtained. Latent class analysis identified 3 groups of patients who had progressively worsening severity and an increasing number of body parts affected. Although the worst itching intensity numerical rating scale and 5-D itch instruments correlated with each other, only the latter had a strong relationship with EQ-5D. When controlling for age, sex, diabetes and years receiving dialysis, the meanpredicted EQ-5D utility (1: perfect health, 0: dead) decreased progressively from 0.69 to 0.41. These findings suggest that pruritus instruments that include domains capturing how the individual is physically, mentally and socially affected by their pruritus, in addition to severity, more closely approximate the EQ-5D generic quality of life measure.

Early outcomes of peritoneal dialysis in a middle-income country: A retrospective cohort study of a large dialysis network in Colombia.

The first year of dialysis is critical given the significant risk for complications following dialysis initiation. We analysed complications during the first year among incident peritoneal dialysis (PD) patients. This retrospective cohort study comprised adult kidney failure patients starting PD in Baxter Renal Care Services in Colombia, receiving their first PD catheter between 1 January 2017 and 31 December 2020 and were followed up for up to 1 year. We analysed incidence, causes and factors associated with complications using logistic regression and transfer to haemodialysis (HD) using the Fine-Gray regression model. Among 4743 patients receiving their first PD catheter: 4628 (97.6%) of catheter implantations were successful; 377 (7.9%) patients experienced early complications. The incidence rate of complications during the year was 0.51 events per patient-year (95% CI: 0.48-0.54). Age, obesity and urgent start were associated with higher probability of complications after catheter implantation. The cumulative incidence of transfer to HD within 1 year of PD initiation was 10.1% [95% CI: 9.2-11.1%]. The hazard function for transfer to HD showed an accelerating pattern during the first month followed by progressive decrease during the first year. In this large population of incident PD patients, there is a high primary catheter placement success rate. Urgent start, age ≥65 years, obesity, centre size ≥150 PD patients and diabetes were risk factors associated with early complications. The follow-up of the cohort from day 1 of PD treatment showed that the risk for transfer to HD was higher during the first month.