A267 Aims: In this study we evaluated the quality of life for patients that underwent kidney transplantation. Methods: Our group consisted of 32 patients that were evaluated before transplantation and twelve (12) months after transplantation. The data was collected with interviews in which we used KDQOL-SF (Kidney Disease Quality of Life Short Form). Most of the patients were men (59,4%) and they lived permanently in Athens (68,8%). The mean age of the patients were 49,72 years (SD=11,71) and the mean waiting time for a graft was 4,66 years (SD=3,14). Twenty two patients (68,8%) received cadaveric graft. Results: The quality of life after renal transplantation improved significantly. (In a range of 0-100 Q before=39,76-Q after=83,55, P<0,0001). The greatest improvement attended in relation with the disease symptoms (D=50,85, P<0,0001, with the occurred problems (D=68,67, P< 0,0001) and with the patient activity (D=57,03, P<0,0001) Conclusions: Results showed that in accordance to results of similar studies in the Europe and USA, life quality in patients in hemodialysis improves after kidney transplantation. This study suggests that further research in a systematic base is necessary to determine the effects of interventions and to investigate all other possible factors that may affect the quality of life of these patients.