Background: Globally rice is cultivated under lowland condition. Increasing water scarcity and imbalanced fertilizer application affects the productivity of rice. Effective as well as efficient irrigation method and proper nutrient management enhance the growth and yield of rice besides increasing the input use efficiency. Methods: A field experiment was carried in Agricultural College and Research Institute at Madurai during Kharif season 2022. Design executed was split plot with three main and seven sub plots. Irrigation methods was assigned to main plot and nutrient management to sub plot. Result: The experiment result revealed that adopting alternate wetting and drying irrigation method coupled with combination of 50 percent N and K given as conventional fertilizer + foliar spray of Nano N and K had significant impact on growth attributes, physiological characters and yield beside with limited use of inputs.