Key Participants Research Articles

Communities beyond geographical limitation: The network characteristics of international wildlife trade under the pandemic

The international wildlife trade, contributing billions of dollars to global economies and encompassing thousands of species, has increased due to rising demands for wildlife products. Revealing the key participants and trade characteristics across taxa is imperative for sustaining wildlife resources and conservation efforts. To provide a basis for informed wildlife management and trade supervision, we investigated the global wildlife trade's fundamental characteristics and spatial patterns by analyzing transaction records reported to The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) from 2020 to 2022. During this period, the essential demands for wildlife were highlighted due to stricter trade regulations and higher trade costs in response to the suspected wildlife origin of the pandemic. Our analysis highlights the formation of trade communities that are tightly interconnected by strong trade relations in wildlife trade networks, transcending geographical limitations. Unlike the division of the continents, geographical proximity alone does not necessarily contribute to the formation of these trade communities. Germany emerges as the leading importer based on trade frequency, while the Netherlands leads in exports. The main driving forces behind wildlife trades include commercial use (74.98 %), personal use (3.80 %), and hunting trophies (3.19 %). Apart from 44.90 % of flora trades, Reptilia was the primary traded taxa (21.08 %), involving 196 engaged countries/territories with the most mutual connections (27.21 %) and an average of 12.51 shipments to 11.33 nodes. Aves (9.70 %), Mammalia (9.44 %), and Anthozoa (7.62 %) followed. Notably, certain European and Asian countries/territories dominate the import or export of most trades, exhibiting distinct variations across taxa. The United Arab Emirates led the Aves trade, accounting for 15.96 % of global Aves transactions during this period. Similarly, Italy led the Reptilia trades (21.28 %), South Africa led the Mammalia trades (18.72 %), and Indonesia led the trades in Insecta (56.84 %), Hydrozoa (66.96 %), and Anthozoa (56.12 %). Our findings underscore the traded species facing overexploited and the countries most involved, thereby informing proactive monitoring and policy-making for sustainable wildlife conservation and management.

Analisis Eksplorasi Strategi Perusahaan Dalam Menghadapi Disrupsi Digital Di Era Industri 6.0: Studi Kasus Pada PT. Aneka Tambang Tbk

This qualitative research explores the strategies implemented by PT Aneka Tambang Tbk (ANTAM) in facing digital disruption in the industrial era 6.0. By using a case study approach and involving 10-15 key participants from ANTAM management, this research reveals the company's comprehensive digital transformation efforts. Data collection methods include in-depth interviews, participant observation, document analysis, and literature review. The main strategies implemented include the implementation of digital technology such as the Internet of Things (IoT), big data analytics, automation and robotics in mining operations; digital human resource development; transformation of organizational culture that supports innovation; as well as strategic partnerships and collaborations with technology companies, start-ups and research institutions. ANTAM also pays great attention to aspects of cyber security and data protection. The research results show that digital transformation has a positive impact on increasing operational efficiency, productivity, cost savings, work safety, new product development, as well as the competitiveness and sustainability of ANTAM's business. This research provides valuable insights for companies in the mining sector and related industries in formulating effective digital transformation strategies.

Drug Development Failure: How GLP-1 Development Was Abandoned in 1990.

Many factors determine whether and when a class of therapeutic agents will be successfully developed and brought to market, and historians of science, entrepreneurs, drug developers, and clinicians should be interested in accounts of both successes and failures. Successes induce many participants and observers to document them, whereas failed efforts are often lost to history, in part because involved parties are typically unmotivated to document their failures. The GLP-1 class of drugs for diabetes and obesity have emerged over the past decade as clinical and financial blockbusters, perhaps soon becoming the highest single source of revenue for the pharmaceutical industry (Berk 2023). In that context, it is instructive to tell the story of the first commercial effort to develop this class of drugs for metabolic disease, and how, despite remarkable early success, the work was abandoned in 1990. Told by a key participant in the effort, this story documents history that would otherwise be lost and suggests a number of lessons about drug development that remain relevant today.

Dynamics of Ageing in Akoko Area of Ondo State Nigeria: Challenges of Public Welfare for the Aged

Objectives: The purpose of this study is to investigates the dynamics of ageing in Akoko Land of Ondo State Nigeria and challenges of public welfare for the aged. The Study was anchored on disengagement theory to explain the inevitable process of disengagement as a rewarding and universal that must be mutually agreed upon. Methods: Both quantitative and qualitative data were collected from randomly selected respondents and key informant participants numbering one hundred and forty (140). The quantitative data collected from 120 respondents were analyzed with statistical package for the social sciences, while the qualitative data collected from 20 participants were analyzed using content analysis. Results: Findings revealed that the aged were relatively neglected in term of care and social security. Majority of the respondents 94.2% agreed that extended family system alone cannot stand as a social insurance for the aged. 90% agreed that improvement in the social care and security policies across public and private organization would help to alleviate most aged poverty level. Conclusions: This study recommends, among others, that every family should extend mutual love and care gesture towards their ageing cohort, the aged should themselves engage in proper future savings and investments, while the society, through the non-governmental organizations (NGOs) and the Government should intensify their efforts to provide social security, public infrastructure, medical facility, prompt pension and retirement benefit payment in order to assure graceful ageing for every aged cohort in the society.

Consideration of Mental Health and Well-Being in High-Level Sport: When Will a Coach-Centred Approach Be Introduced?

Coverage of problems relating to mental health and well-being is gaining ground in the sports sector today, both in the media and in the scientific literature. Despite exposure to numerous stressors and suffering from poor mental health, coaches have in general been largely overlooked in the scientific literature. Previous studies have mainly focused upon athlete populations. The absence of research means that there are real shortcomings in both understanding the mechanisms involved in the deterioration of coaches’ mental health and well-being and in the lack of specific support systems available. This paper first describes findings from the recent, albeit quite scarce, research investigating mental health and well-being in coaches. It then proposes a number of avenues for research and support protocols, both of which are currently ongoing at the French Football Federation Research Centre. The aim is to help support these key participants in the sports sector who arguably have not been given sufficient consideration until now.

Collaborative research practices in the study of diasporisation: chronotopes of dispersion among Hungarians in Catalonia

ABSTRACT Diasporas and diasporisation have lately been at the centre of interest in sociolinguistic inquiry. Literature on the inclusion of diasporic speakers in academic knowledge production in connection with diasporas is scarce, although this would be of crucial importance to achieve ‘thinking diaspora from below’ (Rosa and Trivedi 2017. “Diaspora and Language.” In The Routledge Handbook of Migration and Language, edited by Suresh Canagarajah, 330–346. London: Routledge) when researching sociolinguistic phenomena. In this article, I discuss an ethnographically informed critical sociolinguistic study of diasporisation among Hungarians in Catalonia between 2018 and 2022 in which I applied collaborative research practices with the key participants. These practices consisted of the joint formulation of questions, the creation of a reflexive diasporic space, and feedback provided in the post-fieldwork phase. I address how these methods contributed to the emergence of a chronotopic approach to diasporisation. I argue that the inclusion of the emic perspectives of diasporic speakers through their involvement in the research process is a fruitful way to approach diasporas and diasporisation. Moreover, by paying attention to the needs and interests of the participants, this way of researching on, for, and with the participants also contributes to better understandings of diasporisation.

Identification of NR3C2 as a functional diagnostic and prognostic biomarker and potential therapeutic target in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC), including the lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) subtypes, is a malignant tumor type with a poor 5-year survival rate. The identification of new powerful diagnostic biomarkers, prognostic biomarkers, and potential therapeutic targets in NSCLC is urgently required. The UCSC Xena, UALCAN, and GEO databases were used to screen and analyze differentially expressed genes, regulatory modes, and genetic/epigenetic alterations in NSCLC. The UCSC Xena database, GEO database, tissue microarray, and immunohistochemistry staining analyses were used to evaluate the diagnostic and prognostic values. Gain-of-function assays were performed to examine the roles. The ESTIMATE, TIMER, Linked Omics, STRING, and DAVID algorithms were used to analyze potential molecular mechanisms. NR3C2 was identified as a potentially important molecule in NSCLC. NR3C2 is expressed at low levels in NSCLC, LUAD, and LUSC tissues, which is significantly related to the clinical indexes of these patients. Receiver operating characteristic curve analysis suggests that the altered NR3C2 expression patterns have diagnostic value in NSCLC, LUAD, and especially LUSC patients. Decreased NR3C2 expression levels can help predict poor prognosis in NSCLC and LUAD patients but not in LUSC patients. These results have been confirmed both with database analysis and real-world clinical samples on a tissue microarray. Copy number variation contributes to low NR3C2 expression levels in NSCLC and LUAD, while promoter DNA methylation is involved in its downregulation in LUSC. Two NR3C2 promoter methylation sites have high sensitivity and specificity for LUSC diagnosis with clinical application potential. NR3C2 may be a key participant in NSCLC development and progression and is closely associated with the tumor microenvironment and immune cell infiltration. NR3C2 co-expressed genes are involved in many cancer-related signaling pathways, further supporting a potentially significant role of NR3C2 in NSCLC. NR3C2 is a novel potential diagnostic and prognostic biomarker and therapeutic target in NSCLC.

Biomaterials-Based Technologies in Skeletal Muscle Tissue Engineering.

For many clinically prevalent severe injuries, the inherent regenerative capacity of skeletal muscle remains inadequate. Skeletal muscle tissue engineering (SMTE) seeks to meet this clinical demand. With continuous progress in biomedicine and related technologies including micro/nanotechnology and 3D printing, numerous studies have uncovered various intrinsic mechanisms regulating skeletal muscle regeneration and developed tailored biomaterial systems based on these understandings. Here, the skeletal muscle structure and regeneration process are discussed and the diverse biomaterial systems derived from various technologies are explored in detail. Biomaterials serve not merely as local niches for cell growth, but also as scaffolds endowed with structural or physicochemical properties that provide tissue regenerative cues such as topographical, electrical, and mechanical signals. They can also act as delivery systems for stem cells and bioactive molecules that have been shown as key participants in endogenous repair cascades. To achieve bench-to-bedside translation, the typical effect enabled by biomaterial systems and the potential underlying molecular mechanisms are also summarized. Insights into the roles of biomaterials in SMTE from cellular and molecular perspectives are provided. Finally, perspectives on the advancement of SMTE are provided, for which gene therapy, exosomes, and hybrid biomaterials may hold promise to make important contributions.

Morphogenetic and growth factors in damaging to the dentin-pulp complex and periodontium

Morphogenetic and growth molecules, a key participant in reparative dentinogenesis, determine viability of the dentin-pulp complex (DPC), periodontium and dentogingival junction. They are secreted in microvessels, nerve fibers and connective tissue cells of the dental pulp, exerting homeostatic influence on the immediate surrounding. The present paper reviews the data on the localization of growth factors and signaling mechanisms that control histogenesis and reparative processes in the DPC. The paper points out the significance of these factors in the regulation of proinflammatory and immunocompetent cells in caries, periodontitis and osteoinductive processes in the alveolar outgrowth. The study of growth molecules appears crucial in the development of the latest clinical strategies to maintain the viability of the DPC and to integrate artificial materials in dental tissue restoration.

Infrastructural entanglements: the Autobahnüberbauung Schlangenbader Straße in Berlin-Wilmersdorf

This paper puts forward the Autobahnüberbauung Schlangenbader Straße development, constructed in Berlin-Wilmersdorf during the 1970s, as a compelling juxtaposition of architecture and urban infrastructure. To that end, it draws from both Science and Technology Studies (STS) and urban-architectural scholarship to unpack some of the intertwined technical, social, political, and aesthetic dimensions of urban infrastructures. Subsequently, it examines the role that architecture might play in integrating the diverse solicitations of these dimensions in the city. Positing the notion of ‘entanglement’ to characterise the unique form of infrastructural integration afforded by the Schlangenbader Straße complex, the argument proceeds to consider this integration from three different angles. First, it positions the development in relation to the emergence of West Berlin's urban motorcar infrastructure throughout the twentieth century, exploring its technical and socio-political aspirations. Second, it presents two sets of architectural imaginaries (dating from the 1920s and 60s, respectively) that articulated preceding — yet unrealised — narratives of mass transit integration and extended urban connectivity. Third, it scrutinises the specific infrastructural dimensions of the Schlangenbader Straße complex by identifying the main technical, social, and political aspects that informed its development and construction, delving into the roles and attitudes of key participants in the process. The conclusion reinforces the position of the Autobahnüberbauung Schlangenbader Straße as a socio-technical artefact, deeply ‘entangled’ with Berlin's urban infrastructure.

Development and psychometric properties of an instrument to measure perception of aphrodisiac use among undergraduates in a southwestern Nigerian university.

A tool to measure perception of aphrodisiac use by undergraduates students of University of Ibadan, Oyo State, Nigeria was developed and validated. The study was hinged on several theories that could explain potential to use aphrodisiac among the youths. An exploratory mixed methods design was used to develop a scale to measure perception of aphrodisiac use by undergraduate students of University of Ibadan. Qualitative data collection was performed among thirty equally represented male and female students and five key informant interview participants while 919 participants completed the quantitative phase (surveys). Integration of matched qualitative themes from FGD/KII to survey domains was achieved through the 'building approach'. Qualitative themes assessing perceptions of aphrodisiac use by university undergraduate students were used to develop original survey items as well as new survey items peculiar to research subjects. Exploratory factor analysis was deployed on polychoric correlation matrix of the items using R-statistical packages. Further model fit analysis was conducted using confirmatory factor analysis on the items suggested by EFA as well as composite reliability and construct validity tests for the constructs. Mean Z-scores of factors were computed against socio-demographics and symptoms of aphrodisiac use among respondents that have ever used it. Most respondents (84.3%) were under 25 years, mostly male (58.4%) and singles (96.3%), with 41.3% earning ≤20,000 naira monthly. The enhanced content validity of the items from mixed method analysis yielded two major domains. Two succession of factor analyses and a structural equation modeling suggested that a first-order model is good fit for experimental data (TLI = 0.931; CFI = 0.948; SRMR = 0.047; RMSEA = 0.083). The four-factor solution to the model included: prolonged sexual performance, use without erectile dysfunction or medical advice, treatment of erectile dysfunction and recreational purposes with an internal and composite reliability that ranged from 0.62-0.92 and 0.63-0.92. The validation with socio-demographics and consequences of aphrodisiac use indicated that: Male respondents, those older than 20years, the married, those from poorly educated parent and sufferers of all related consequences had statistically significant differences with poor perception of aphrodisiac use' domains. This validated instrument is good for assessment of perception of aphrodisiac use among students in tertiary institution albeit with caution. A version of the scale that is broadened with highly refined items and tested for high internal validity is suggested.

Deciphering the Genetic Links between Psychological Stress, Autophagy, and Dermatological Health: Insights from Bioinformatics, Single-Cell Analysis, and Machine Learning in Psoriasis and Anxiety Disorders.

The relationship between psychological stress, altered skin immunity, and autophagy-related genes (ATGs) is currently unclear. Psoriasis is a chronic skin inflammation of unclear etiology that is characterized by persistence and recurrence. Immune dysregulation and emotional disturbances are recognized as significant risk factors. Emerging clinical evidence suggests a possible connection between anxiety disorders, heightened immune system activation, and altered skin immunity, offering a fresh perspective on the initiation of psoriasis. The aim of this study was to explore the potential shared biological mechanisms underlying the comorbidity of psoriasis and anxiety disorders. Psoriasis and anxiety disorders data were obtained from the GEO database. A list of 3254 ATGs was obtained from the public database. Differentially expressed genes (DEGs) were obtained by taking the intersection of DEGs between psoriasis and anxiety disorder samples and the list of ATGs. Five machine learning algorithms used screening hub genes. The ROC curve was performed to evaluate diagnostic performance. Then, GSEA, immune infiltration analysis, and network analysis were carried out. The Seurat and Monocle algorithms were used to depict T-cell evolution. Cellchat was used to infer the signaling pathway between keratinocytes and immune cells. Four key hub genes were identified as diagnostic genes related to psoriasis autophagy. Enrichment analysis showed that these genes are indeed related to T cells, autophagy, and immune regulation, and have good diagnostic efficacy validated. Using single-cell RNA sequencing analysis, we expanded our understanding of key cellular participants, including inflammatory keratinocytes and their interactions with immune cells. We found that the CASP7 gene is involved in the T-cell development process, and correlated with γδ T cells, warranting further investigation. We found that anxiety disorders are related to increased autophagy regulation, immune dysregulation, and inflammatory response, and are reflected in the onset and exacerbation of skin inflammation. The hub gene is involved in the process of immune signaling and immune regulation. The CASP7 gene, which is related with the development and differentiation of T cells, deserves further study. Potential biomarkers between psoriasis and anxiety disorders were identified, which are expected to aid in the prediction of disease diagnosis and the development of personalized treatments.

Stock market reaction to new energy vehicle industry development plan: an event study in China

ABSTRACT The targets of energy conservation, decarbonization, and industry reinvigoration have significantly influenced the design of China’s new energy vehicle (NEV) industrial policies and nationwide electrification. As a monumental policy framework for energy transition in transportation sector, the NEV industry development plan plays an influential role in promoting cleantech diffusion and enhancing NEV competitiveness. This study employs an event study method to investigate the stock market reaction to the NEV plan shocks. The NEV plan announced in 2020 receives a markedly positive stock price effect of 3.72% in the 6-day event window. Heterogeneity tests on subsamples indicate that state-backed entities exhibit a similar effect to the total sample, while the automotive manufacturing class and original equipment manufacturers see a significantly higher market value gain of 6.56% and 13.34%, respectively. However, battery manufacturers, as one of the key participants in the NEV value chain, experience an insignificant stock price effect. This study documents the financial consequences of clean energy policies specific to the emission-intensive automotive manufacturing sector, highlights the effectiveness of government-to-investor signalling in a cleantech diffusion context, and reveals the implications to other economies seeking to deploy clean transport and enhance environmental sustainability.

Metropolitan Sergius (Stragorodsky): Ministry and Destiny

The article delves into the biography of the future Patriarch Sergius (Stragorodsky) and the circumstances of his life that shaped the personality of the primate, making him one of the most prominent church figures of the twentieth century. The article examines the principal milestones of his pastoral ministry, theological contributions, missionary efforts, and administrative endeavors undertaken for the benefit of the Church. The article also outlines the circumstances surrounding Metropolitan Sergius’ dramatic involvement in the Renovationist schism and his eventual departure from it through a public act of repentance. The focus of the article is the history of relations between the Russian Orthodox Church and the Soviet government in the 1920s and 1930s, with Metropolitan Sergius playing a pivotal role as one of the key participants. The most challenging period for the Church in the twentieth century was the span from 1925 to 1943, marked by the absence of patriarchal authority and characterized by numerous intrigues and administrative pressure from the Bolshevik government. The article argues that the policy of Metropolitan Sergius was a direct continuation of the path that Patriarch Tikhon embarked on in the last years of his tenure. The author of the article concludes that Metropolitan Sergius deliberately chose a compromise with the authorities, embracing the path of martyrdom and self-abasement for the sake of preserving the Church. In 1927, Metropolitan Sergius, along with members of the convened Provisional Patriarchal Holy Synod, signed the “Message to Pastors and Believers”, which served as a memorandum of the Church’s political loyalty to the Soviet government. The article pays significant attention to Sergius’ press conference in front of Soviet and foreign journalists, which served as a response to numerous accusations leveled against the Soviet government for its oppression of the Church. The author of the article concludes that Metropolitan Sergius’ ministry is primarily characterized by martyrdom. Consciously opting for personal dishonor to safeguard the Church stands as a genuine act of courage by Patriarch Sergius, an undeniable merit appreciated by all believers.

Changing the delivery of continuing professional education: An action research approach

AimA participatory action research project was used to change the design and delivery of continuing professional education in a large Irish academic teaching hospital. BackgroundParticipation in continuing professional education, designed as a short course, is often a method to maintain competence for many nurses. Structured short education courses are often used to orientate and upskill new staff to specialist clinical areas. Traditionally many courses relied on face-to-face delivery over a period of weeks which is challenging for one clinical area to release staff to attend theoretical days in person. DesignA six-stage participatory action research cycle over a 3-year period in a large Irish academic teaching hospital. MethodsMultiple methods were used in the cyclical process of participatory action research. Constructive alignment theory and instructional design principles were used to redesign the educational framework. Data collection included audits of courses, questionnaires and focus groups with key participants. ResultsAnalysis of the focus group themes included 1) underestimated time 2) the process of change 3) teaching and learning styles and 4) acceptance and integration. 20 learners completed the evaluation and reported a positive synergy between e-learning and clinical workshops. E-learning was reported as time-consuming. 75 % of learners reported they were motivated to learn. 90 % of the learners reported they gained new knowledge and skills, 84 % reported the clinical area benefited from the education and 80 % identified a direct improvement in their clinical skills in the specialist area. ConclusionsParticipatory action research supports organisational change in continuing professional education. Constructive alignment theory supports the value of outcomes-based learning. In this context it resulted in successfully blending theory and clinical skills for nurses working in specialist areas. The redesigned continuing professional education framework was positively evaluated across nurses in the organisation.

A COMPREHENSIVE STUDY OF HIGH SCHOOL FOOTBALL LEAGUE MANAGEMENT IN NGADA REGENCY, INDONESIA

This study conducts a thorough evaluation of the management processes involved in the 2023 Ngada Regency High School Student League football tournaments hosted at STKIP Citra Bakti. It investigates several critical aspects of football league management, including team management, planning, organization, execution, and evaluation of match outcomes. Utilizing a qualitative descriptive methodology, data was gathered through detailed observations and structured interviews with key participants. The analysis focused on the interplay between antecedents (pre-event preparations), transactions (event execution), and outcomes (post-event evaluation), providing a comprehensive view of management effectiveness. Findings reveal that meticulous pre-event planning and robust organization strategies led to efficient game execution and positive evaluations. Notably, the study identified that proactive conflict resolution during planning phases and adaptive management during games were pivotal in enhancing the event's success. The implications of these findings extend beyond the immediate context, contributing to the broader field of sports management. They underscore the importance of strategic planning and dynamic management in organizing successful student sports events. This research adds to the existing knowledge by demonstrating how integrated management practices can optimize event outcomes and student engagement in sports, suggesting a model that can be replicated in similar contexts globally.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0787/a.php" alt="Hit counter" /></p>

A New Model for Improving Quality of Hypertension’s Determinant Factors in Pregnancy

Background Hypertension in pregnancy should be detected earlier to prevent possible complications of pregnancy such as preeclampsia. Pregnancy hypertension could transform into preeclampsia if unmonitored and untreated, it can even be bad for eclampsia. Purpose This research aims to identify the determinant factors of hypertension during pregnancy and to develop a suitable model to prevent hypertension in the future. Methods The research was developed using a mixed method with an embedded design approach. This study has adopted the ADDIE concept including Analysis, Design, Development, Implementation, and Evaluation steps. Purposive sampling based on knowledge proportion has designated 164 pregnant women as key participants. Qualitative analysis was applied through in-depth interviews. Quantitative analysis was conducted with SEM-PLS. Results The determinant variable components of late detection of hypertension in pregnancy are knowledge and understanding, self-efficacy, intentions, and attitudes of pregnant women. Other variables are also considered as psychosocial support of husband/family and midwives, antenatal care, and service facilities. Conclusion The data shows that the MEGA model is proven to be effective in evaluating the determinant factors of hypertension in pregnancy.

Auditing standards and the persistence of the audit expectations gap: Evidencing the absence of French ‘exceptionalism’

Auditing standards have become a central feature in the world of auditing. One of the primary claims made for International Standards on Auditing (ISAs) is their capacity to reduce the audit expectations gap (AEG), but the gap persists despite the widespread adoption of ISAs. France is an intriguing case site for studying the development and impact of audit standard setting, especially given its reputation as a country for maintaining its own distinctive audit regulatory traditions. Its claimed resistance to Anglo‐American influences, however, is not what stands out in our archival analysis of French audit standard‐setting processes and an accompanying series of interviews with key participants. In contrast, the French audit standard setting emerges as a process that has largely aligned with the spirit of ISAs and adopted a narrow interpretation of the AEG. The presented analysis challenges the operational significance of a claimed French exceptionalism and adds to a growing questioning of the capacity of auditing standard setting to drive fundamental advancement in auditing practice and to meet public expectations.

Transcription factors as molecular switches regulating plant responses to drought stress.

Plants often experience abiotic stress, which severely affects their growth. With the advent of global warming, drought stress has become a pivotal factor affecting crop yield and quality. Increasing numbers of studies have focused on elucidating the molecular mechanisms underlying plant responses to drought stress. As molecular switches, transcription factors (TFs) are key participants in drought-resistance regulatory networks in crops. TFs regulate the transcription of downstream genes and are regulated by various upstream regulatory factors. Therefore, understanding the mechanisms of action of TFs in regulating drought stress can help enhance the adaptive capacity of crops under drought conditions. In this review, we summarize the structural characteristics of several common TFs, their multiple drought-response pathways, and recently employed research strategies. We describe the application of new technologies such as analysis of stress granule dynamics and function, multi-omics data, gene editing, and molecular crosstalk between TFs in drought resistance. This review aims to familiarize readers with the regulatory network of TFs in drought resistance and to provide a reference for examining the molecular mechanisms of drought resistance in plants and improving agronomic traits.

Tourism photography: a form of adaptation to sustain the heritage district of Malioboro, Yogyakarta

The study discusses the role of tourism photography in the increasing existence and sustainability of heritage areas in Yogyakarta. Tourism photography has become a lifestyle trend in the current digital era. The principle of tourism photography as a promotion media of tourism objects and destinations contributes to the increasing popularity of the heritage areas in Yogyakarta as the uniqueness of urban tourism in Yogyakarta. Tourism photography is developing in the heritage area of Malioboro. It can be seen as an opportunity and a threat for the district as well. Therefore, the study aims to find out the sites and their architectural characteristics that are used as the setting of tourism photography. The study implemented an explorative case study method with Malioboro heritage area as the case study. Data was collected through a participatory observation, interviews with key persons and participants, and relevant documents. The results of the study shows that tourism photography plays a key role in the preservation of heritage buildings in the Malioboro heritage area. The activities of tourism photography in the Malioboro area involve the local community as the actors of tourism photography, such as photographers, renting traditional costumes and preparing the local transportation. The active participation of the local community gives financial benefits for the community. Furthermore, the old buildings are well maintained, so that they become more attractive for tourists. It can be said that tourism photography contributes to the effort to maintain the heritage buildings in Malioboro, Yogyakarta.