Key Muscle Groups Research Articles

Muscle structure predictors of vertical jump performance in elite male volleyball players: a cross-sectional study based on ultrasonography.

The objective of this investigation is to examine the contribution of key muscle groups in the lower limbs to vertical jumping performance in elite male volleyball players. Specifically, the study focuses on the rectus femoris (RF), vastus lateralis (VL), and lateral gastrocnemius (LG), as well as exploring differences between attack jump and other vertical jump types. To achieve this, we employed B-mode ultrasound to evaluate the anatomical cross-sectional area (ACSA), muscle thickness (MT), pennation angle (PA), and fascicle length (FL) of the RF, VL, and LG in the participants. Fifteen elite male volleyball players were recruited as participants for this study. Jump heights were measured for four types of vertical jumps: attack jump (AJ), countermovement jump (CMJ), squat jump (SJ), and drop jump (DJ). We conducted regression analyses to assess whether the previously mentioned muscle structures could predict jump performance. Our findings reveal that the muscle structure of the RF does not exhibit any significant correlation with the height of any jump. However, VL-ACSA displays a significant and the most potent predictive effect on jump height for all four jump types (AJ: R 2 = 0.32, p = 0.001; CMJ: R 2 = 0.37, p = 0.005; SJ: R 2 = 0.52, p = 0.001; DJ: R 2 = 0.25, p = 0.021). Conversely, LG-FL only demonstrates a significant and stronger predictive effect on AJ jump height (R 2 = 0.18, p = 0.009). Combining VL-ACSA, LG-FL, and training age through multiple linear regression analysis resulted in a highly significant model for predicting AJ jump height (F = 13.86, R 2 = 0.73). Moreover, the model incorporating VL-ACSA and training age is also important for predicting CMJ, SJ, and DJ jump heights (F = 8.41, R 2 = 0.51; F = 13.14, R 2 = 0.63; F = 5.95, R 2 = 0.41; respectively). The muscle structure indicators in the lower limbs significantly predict jump performance among elite male volleyball players. However, different jump types are influenced by distinct indicators, particularly in the case of AJ, which is associated with LG-FL. This suggests that enhancing LG-FL may positively impact AJ ability, thereby emphasizing the importance of specificity in training. To optimize specialized jump performance in volleyball players, practitioners are advised to assess VL-ACSA and LG-FL and incorporate step-up and eccentric strength training targeting the calf muscles to yield considerable benefits.

A retrospective evaluation of individual thigh muscle volume disparities based on hip fracture types in followed-up patients: an AI-based segmentation approach using UNETR.

Hip fractures are a common and debilitating condition, particularly among older adults. Loss of muscle mass and strength is a common consequence of hip fractures, which further contribute to functional decline and increased disability. Assessing changes in individual thigh muscles volume in follow-up patients can provide valuable insights into the quantitative recovery process and guide rehabilitation interventions. However, accurately measuring anatomical individual thigh muscle volume can be challenging due to various, labor intensive and time-consuming. This study aimed to evaluate differences in thigh muscle volume in followed-up hip fracture patients computed tomography (CT) scans using an AI based automatic muscle segmentation model. The study included a total of 18 patients at Gyeongsang National University, who had undergone surgical treatment for a hip fracture. We utilized the automatic segmentation algorithm which we have already developed using UNETR (U-net Transformer) architecture, performance dice score = 0.84, relative absolute volume difference 0.019 ± 0.017%. The results revealed intertrochanteric fractures result in more significant muscle volume loss (females: -97.4 cm3, males: -178.2 cm3) compared to femoral neck fractures (females: -83 cm3, males: -147.2 cm3). Additionally, the study uncovered substantial disparities in the susceptibility to volume loss among specific thigh muscles, including the Vastus lateralis, Adductor longus and brevis, and Gluteus maximus, particularly in cases of intertrochanteric fractures. The use of an automatic muscle segmentation model based on deep learning algorithms enables efficient and accurate analysis of thigh muscle volume differences in followed up hip fracture patients. Our findings emphasize the significant muscle loss tied to sarcopenia, a critical condition among the elderly. Intertrochanteric fractures resulted in greater muscle volume deformities, especially in key muscle groups, across both genders. Notably, while most muscles exhibited volume reduction following hip fractures, the sartorius, vastus and gluteus groups demonstrated more significant disparities in individuals who sustained intertrochanteric fractures. This non-invasive approach provides valuable insights into the extent of muscle atrophy following hip fracture and can inform targeted rehabilitation interventions.

Guided Self-rehabilitation Contract vs conventional therapy in chronic peripheral facial paresis: VISAGE, a multicenter randomized controlled trial

BackgroundOne year after persistent peripheral facial paresis (PFP), prescriptions of conventional rehabilitation are often downgraded into maintenance rehabilitation or discontinued, the patient entering what is seen as a chronic stage. This therapeutic choice is not consistent with current knowledge about behavior-induced plasticity, which is available all life long and may allow intense sensorimotor rehabilitation to remain effective. This prospective, randomized, multicenter single-blind study in subjects with chronic unilateral PFP evaluates changes in facial motor function with a Guided Self-rehabilitation Contract (GSC) vs. conventional therapy alone, carried out for six months.MethodsEighty-two adult subjects with chronic unilateral PFP (> 1 year since facial nerve injury) will be included in four tertiary, maxillofacial surgery (2), otolaryngology (1) and rehabilitation (1) centers to be randomized into two rehabilitation groups. In the experimental group, the PM&R specialist will implement the GSC method, which for PFP involves intensive series of motor strengthening performed daily on three facial key muscle groups, i.e. Frontalis, Orbicularis oculi and Zygomatici. The GSC strategy involves: i) prescription of a daily self-rehabilitation program, ii) teaching of the techniques involved in the program, iii) encouragement and guidance of the patient over time, in particular by requesting a quantified diary of the work achieved to be returned by the patient at each visit. In the control group, participants will benefit from community-based conventional therapy only, according to their physician’s prescription. The primary outcome measure is the composite score of Sunnybrook Facial Grading System. Secondary outcome measures include clinical and biomechanical facial motor function quantifications (Créteil Scale and 3D facial motion analysis through the Cara system), quality of life (Facial Clinimetric Evaluation and Short-Form 12), aesthetic considerations (FACE-Q scale) and mood representations (Hospital Anxiety and Depression scale). Participants will be evaluated every three months by a blinded investigator, in addition to four phone calls (D30/D60/D120/D150) to monitor compliance and tolerance to treatment.DiscussionThis study will increase the level of knowledge on the effects of intense facial motor streng- Facial paralysisthening prescribed through a GSC in patients with chronic peripheral facial paresis.Trial registrationClinicalTrials.gov, NCT04074018. Registered 29 August 2019.Protocol versionVersion N°4.0—04/02/2021.

Growth constraints set an upper limit to theropod dinosaur body size

Despite nearly 200years of scientific collecting and study, none of the extinct, bipedal, predatory, theropod dinosaurs have been reliably shown to exceed 12m in length. Using digital 3D models of theropods with lengths spanning 80cm to 12m, their body masses were found to scale to the 3.5 power of body lengths. The lateral area of the pelvis and the cross-sectional area of the tail base of these animals corresponds to the cross-sectional areas of key muscle groups important for balance and locomotion, and both scale to the 2.4 power of body length. Body accelerations in the lateral and forward directions are, using F = ma, given by dividing muscle area (force proxy) by body mass. Plotting these acceleration estimates against body length shows them to decrease exponentially. The largest theropods with body lengths of 10-12m have less than 10% of the acceleration capacity of the smaller forms. The distinct lack of fossil remains of theropods demonstrably longer than 12m suggests that the theropod body plan had an upper size limit based on a minimum acceleration threshold. Rotational inertia of the theropod body was found to be proportional to body length raised to the 5.5 power, and with increasing length, the capacity for agility would rapidly diminish. The tight relationship between theropod pelvic area and body length allows for the estimation of body lengths of specimens lacking complete axial skeletons, and this is done for four, large, well-preserved pelves.

Associação entre medidas de força isocinética e desempenho funcional em pessoas idosas da comunidade

ABSTRACT Previous studies have shown an association between lower limb muscle strength and functional performance, but a dose-response relationship between the strength of each lower limb muscle group and performance in daily life activities in older adults has not been well established. Thus, this study aimed to investigate the association between isokinetic muscle strength of all eight major lower limb muscle groups and functional performance in community-dwelling older adults. The muscle strength of the plantar flexors and dorsiflexors of the ankle, flexors and extensors of the knee, and flexors, extensors, adductors, and abductors of the hip were evaluated using a Biodex System 4 Pro® isokinetic dynamometer. Functional performance was evaluated in 109 participants using the five-times sit-to-stand test (STS) and 4-meter usual walking speed (UWS). The multiple linear regression analyses showed that the hip abductors strength predicted 31.3% of the variability for UWS (p=0.011), and the knee extensors strength (p=0.015) predicted 31.6% of the variability for the STS. We conclude that hip abductors and knee extensors could be the key muscle groups involved in sit to stand and walking speed performance in older adults.

Patient Factors Affect Ergonomic Strain of Endoscopists During Colonoscopy.

Endoscopic procedures place a great deal of muscular strain on providers, especially over the span of their careers. In this study we quantitatively analyzed the effects of patient factors such as age, body mass index, and sex on the ergonomics of endoscopists performing colonoscopies. Surface electromyography (sEMG) was used to measure ergonomic strain of physicians while performing colonoscopies in several key muscle groups. The percent of the maximum voluntary contraction (%MVC) was used as a measure of muscular strain. Data was then analyzed based on the patient characteristics above. Endoscopists performing colonoscopies on female patients (n = 47) experienced significantly higher ergonomic strain in their right trapezius and right posterior forearm muscle groups when compared to colonoscopies performed on males (n = 35) (%MVC R-trapezius: Male: 8.2; Female: 8.9; p = 0.048); (%MVC R-posterior forearm: Male: 10.4; Female: 11.6; p = 0.0006). Operators experienced greater strain in the same muscle groups when performing colonoscopies on patients with BMI ≤ 25 (n = 25) when compared to patients with BMI > 25 (n = 57) (%MVC R-trapezius: BMI < 25: 9.7; BMI ≥ 25: 8.2; p = 0.0002); (%MVC R-posterior forearm: BMI < 25: 11.9; BMI ≥ 25: 10.8; p = 0.0001). Physicians experienced greater ergonomic strain when performing colonoscopies on female patients and on patients with a BMI < 25. We believe that these factors potentially impact the tortuosity of the colon and therefore influence the difficulty of navigating the endoscope. These results may aid physicians in gauging the anticipated difficulty of colonoscopies based on patient factors. Increased awareness of their posturing and ergonomics during challenging cases will alleviate musculoskeletal injuries in the long run.

Postural Health in Physical Education

Working and learning from home as a result of the COVID-19 pandemic resulted in a national decline in physical activity. This, coupled with excessive sitting from remote learning, can lead to postural complications with negative consequences. This article offers physical educators the tools to educate students on how to assess their posture, strengthen or lengthen key muscle groups, and perform appropriate exercises to avoid headaches, back pain, and spinal degeneration. A workout routine along with supporting photos and illustrations are included.

Muscle usage and workload assessment of cardiac ablation procedure with the use of a novel catheter torque tool in a pediatric simulator.

Cardiac ablation catheters are small in diameter and pose ergonomic challenges that can affect catheter stability. Significant finger dexterity and strength are necessary to maneuver them safely. We evaluated a novel torque tool to reduce muscle activation when manipulating catheters and improve perceived workload of ablation tasks. The objective was to evaluate measurable success, user perception of workload, and muscle usage when completing a simulated ablation task with and without the use of a catheter torque tool. Cardiology attendings and fellows were fitted with surface electromyographic (EMG) sensors on 6 key muscle groups in the left hand and forearm. A standard ablation catheter was inserted into a pediatric cardiac ablation simulator and subjects navigated the catheter tip to 6 specific electrophysiologic targets, including a 1-min simulated radiofrequency ablation lesion. Time to complete the task, number of attempts required to complete the lesion, and EMG activity normalized to percentage of maximum voluntary contraction were collected throughout the task. The task was completed 4 times, twice with and twice without the torque tool, in semi-randomized order. A NASA Task Load Index survey was completed by the participant at the conclusion of each task. Time to complete the task and number of attempts to create a lesion were not altered by the tool. Subjectively, participants reported a significant decrease in physical demand, effort, and frustration, and a significant increase in performance. Muscle activation was decreased in 4 of 6 muscle groups. The catheter torque tool may improve the perceived workload of cardiac ablation procedures and reduce muscle fatigue caused by manipulating catheters. This may result in improved catheter stability and increased procedural safety.

Abstract 11194: Reducing Arm Muscle Activation by Using an Ablation Catheter Torque Tool: Electromyographic Analysis and User Perception

Background: Cardiac ablation catheters are small in diameter and require significant finger dexterity and grip strength to maintain stability and maneuver safely. We designed a catheter torque tool to reduce the muscle activation required to manipulate cardiac ablation catheters and improve user perception of task workload. Objective: The purpose of this study was to evaluate muscle usage and user perception when completing a simulated ablation task with and without the use of a novel ablation catheter torque tool. Methods: Participants, comprised of cardiology attendings and fellows, were fitted with surface electromyographic (EMG) sensors on 6 key muscle groups in the left hand and forearm. Maximum voluntary contraction (MVC) was collected for equal comparison among participants. A standard ablation catheter was inserted into a pediatric cardiac ablation simulator and subjects navigated the catheter tip to 6 specific electrophysiologic targets including a 1-minute simulated radiofrequency lesion. EMG activity normalized to percentage of MVC was collected throughout the task. The task was repeated 4 times, twice with and twice without the torque tool, in randomized order. A NASA Task Load Index (TLX) survey was completed by the participant at the conclusion each task. Results: Thirteen participants completed the study. Using Wilcoxon’s test, there was a significant difference (P &lt; 0.01) in mean percent of MVC in 4 of the 6 muscle groups when comparing bare catheter versus catheter with torque tool: abductor pollicis, brachioradialis, flexor carpi ulnaris, and extensor carpi radialis. The total expended energy for the abductor pollicis (P &lt; 0.01) and extensor carpi radialis (P = 0.02) were significantly reduced. Perceived physical demand, effort, and frustration were also significantly reduced when using the torque tool (P &lt; 0.01). Conclusions: Use of our novel catheter torque tool reduced the amount of muscle activation necessary to manipulate an ablation catheter during a simulated ablation task. Users’ perceived physical demand, effort, and frustration were less when the tool was used. This tool may improve catheter stability, increase procedure safety, and reduce operator stress and muscle fatigue when performing catheter ablation procedures.

Impact of isometric exercising as to development of physical characteristics typical of dorsopathy patients at incomplete remission stage

BACKGROUND: The positive impact of isometric exercising, which makes muscle strength indicators grow, has been known for a long time. However, very few studies have been devoted so far to the examination and assessment of the effect in terms of their application for practical healthcare purposes.&#x0D; AIM: It is aimed to assess how a therapeutic isometric exercising impacts the dynamics of basic physical conditions of abdominal and back muscle groups as well as the decrease in pain syndrome severity, which Lumbar spine dorsopathy patients have during an incomplete remission state after the treatment is over and in a remote period (in six-month period).&#x0D; MATERIALS AND METHODS: The retrospective analysis of data based on clinical and functional examination methods and treatment results was conducted involving 72 patients aged 2550 years old with the confirmed dorsopahy diagnosis. The data were acquired with the use of FSSD profile and tension dynamometry Back-Check Dr. Wolff (Physiomed Elektromedizin AG, Germany). The visual analogue scale (VAS) was applied to determine the pain syndrome intensity.&#x0D; RESULTS: Further analysis of the acquired results showed the increased rate of the BPC indicators of strength (p 0.05) and endurance to static and dynamic loads produced with the key posture-dependent muscle groups (p 0.05) as well as decreased intensity of the pain syndrome the dorsopathy patients had (p 0.05).&#x0D; CONCLUSION: Isometric exercising helps to lower the pain syndrome intensity assessed as per the VAS (p 0.05), increase the muscle strength and the core endurance towards static and dynamic loads.

Selection of EMG Sensors Based on Motion Coordinated Analysis.

The intelligent prosthesis driven by electromyography (EMG) signal provides a solution for the movement of the disabled. The proper position of EMG sensors can improve the prosthesis’s motion recognition ability. To exert the amputee’s action-oriented ability and the prosthesis’ control ability, the EMG spatial distribution and internal connection of the prosthetic wearer is analyzed in three kinds of movement conditions: appropriate angle, excessive angle, and angle too small. Firstly, the correlation characteristics between the EMG channels are analyzed by mutual information to construct a muscle functional network. Secondly, the network’s features of different movement conditions are analyzed by calculating the characteristic of nodes and evaluating the importance of nodes. Finally, the convergent cross-mapping method is applied to construct a directed network, and the critical muscle groups which can reflect the user’s movement intention are determined. Experiment shows that this method can accurately determine the EMG location and simplify the distribution of EMG sensors inside the prosthetic socket. The network characteristics of key muscle groups can distinguish different movements effectively and provide a new strategy for decoding the relationship between limb nerve control and body movement.

Muscle Size and Quality of the Gluteal Muscles and Tensor Fasciae Latae in Women with Greater Trochanteric Pain Syndrome.

Greater trochanteric pain syndrome (GTPS) is prevalent in women and severely impacts quality of life. A key muscle group demonstrating reduced strength are the hip abductors. An understanding of specific muscles affected will help guide targeted rehabilitation. Objectives of this case-control study were to compare gluteal and tensor fasciae latae (TFL) muscle size and quality (fatty infiltration) in women with symptomatic GTPS to asymptomatic age-matched female controls. Magnetic resonance imaging of 16 women with GTPS (mean age 55.75 years, range 23-69) and 15 asymptomatic controls (mean age 55.60 years, range 31-66) was undertaken. Muscle volumes of the gluteus maximus, gluteus medius, gluteus minimus, and TFL were calculated. Fatty infiltration was rated using the Goutallier classification system for all muscles in their entirety, as well as anterior and posterior segments of gluteus medius and minimus. Muscle volumes and fatty infiltration were compared between groups. Significantly smaller muscle volumes were identified in the symptomatic group for the upper (P = 0.01) and lower (P = 0.04) portions of gluteus maximus, gluteus medius (P = 0.03), and gluteus minimus (P = 0.02). There was no difference in TFL (P = 0.18). Symptomatic participants displayed significantly greater fatty infiltration in gluteus maximus upper (P = 0.021) and lower (P = 0.049) when adjusted for BMI, and gluteus minimus (P = 0.018), particularly in the posterior portion (P = 0.04). Anterior gluteus minimus demonstrated high amounts of fatty infiltration in both groups. Gluteal muscle atrophy and fatty infiltration in women with GTPS suggests gluteus maximus and minimus may be an important target for rehabilitation. Clin. Anat., 33:1082-1090, 2020. © 2019 Wiley Periodicals, Inc.

Bowel Outcome Prediction After Traumatic Spinal Cord Injury: Longitudinal Cohort Study

Background. Predicting functional outcomes after traumatic spinal cord injury (SCI) is essential for counseling, rehabilitation planning, and discharge. Moreover, the outcome prognosis is crucial for patient stratification when designing clinical trials. However, no valid prediction rule is currently available for bowel outcomes after a SCI. Objective. To generate a model for predicting the achievement of independent, reliable bowel management at 1 year after traumatic SCI. Methods. We performed multivariable logistic regression analyses of data for 1250 patients with traumatic SCIs that were included in the European Multicenter Study about Spinal Cord Injury. The resulting model was prospectively validated on data for 186 patients. As potential predictors, we evaluated age, sex, and variables from the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) and the Spinal Cord Independence Measure (SCIM), measured within 40 days of the injury. A positive outcome at 1 year post-SCI was assessed with item 7 of the SCIM. Results. The model relied on a single predictor, the ISNCSCI total motor score—that is, the sum of muscle strengths in 5 key muscle groups in each limb. The area under the receiver operating characteristics curve (aROC) was 0.837 (95% CI: 0.815-0.859). The prospective validation confirmed high predictive power: aROC = 0.817 (95% CI: 0.754-0.881). Conclusions. We generated a valid model for predicting independent, reliable bowel management at 1 year after traumatic SCI. Its application could improve counseling, optimize patient-tailored rehabilitation planning, and become crucial for appropriate patient stratification in future clinical trials.

Construction and analysis of muscle functional network for exoskeleton robot

Exoskeleton nursing robot is a typical human-machine co-drive system. To full play the subjective control and action orientation of human, it is necessary to comprehensively analyze exoskeleton wearer's surface electromyography (EMG) in the process of moving patients, especially identifying the spatial distribution and internal relationship of the EMG information. Aiming at the location of electrodes and internal relation between EMG channels, the complex muscle system at the upper limb was abstracted as a muscle functional network. Firstly, the correlation characteristics were analyzed among EMG channels of the upper limb using the mutual information method, so that the muscle function network was established. Secondly, by calculating the characteristic index of network node, the features of muscle function network were analyzed for different movements. Finally, the node contraction method was applied to determine the key muscle group that reflected the intention of wearer's movement, and the characteristics of muscle function network were analyzed in each stage of moving patients. Experimental results showed that the location of the myoelectric collection could be determined quickly and efficiently, and also various stages of the moving process could effectively be distinguished using the muscle functional network with the key muscle groups. This study provides new ideas and methods to decode the relationship between neural controls of upper limb and physical motion.

Analysis of the Kinesiology of Skate Skiing and Roller Skiing

The peak of human locomotive ontogenesis is unsupported bipedal walking. We can assume that the patterns for locomotion in sport correspond to the patterns for walking. In this study the coordination of motion in six selected key muscle groups and one control group was observed during the use of cross-country skis with ski-poles on snow (free form, skating), and compared with the coordination using roller skis with poles on asphalt. The comparison was carried out skating up a slight slope. Intraindividual analysis of these forms of locomotion was based on surface electromyography (EMG) synchronized with digital video recorded in vivo on site. The data acquired were evaluated by calculating the area under the EMG curve recorded for each muscle under observation. The probability values acquired in this way roughly show the activation and work of the monitored muscle. An ordering of local maximums within a given step cycle was established in order to judge the coordination of motion. The measured data confirmed the phenomenon of triple extension in the lower limbs as well as the phenomenon of pelvic stabilisation in the frontal plane in the single-support position. This stabilisation is ensured by the musculus gluteus medius, which was the only muscle measured to show a different ordering of local EMG curve maximums (timing) when comparing the whole cycle of skiing locomotion on asphalt and on snow. The peaks of activity for this muscle were localised outside the activity peaks of the musculus latissimus dorsi, which is considered the deciding muscle for locomotion realised through the shoulder girdle, but which also performs a stabilising function. Thus both muscles alternate in ensuring stability. The results of the pilot study described demonstrate sufficient kinesiological correspondence between locomotion on skis and on roller skis with poles to confirm the suitability of regular use of roller skis as a specific training instrument for skiing.Keywords: human locomotion, electromyography, skating on cross-country skis and on roller skis.

Gluteal muscle size and fatty infiltration in women with greater trochanteric pain syndrome

Introduction: Greater trochanteric pain syndrome (GTPS) is a debilitating, chronic condition, most prevalent in women. Physical function, such as walking, is impaired in people with GTPS, severely impacting quality of life. In addition, a key muscle group with demonstrable reduction in strength are the hip abductors. An understanding of the specific muscles affected will help guide targeted rehabilitation options. Current evidence for gluteal muscle size changes in people with GTPS is scarce, with methodological limitations, and fatty infiltration has not yet been described in this population. This study aimed to compare gluteal muscle size and fatty infiltration using magnetic resonance imaging (MRI) in women with symptomatic GTPS compared to asymptomatic controls.

Functional Identification and Characterization of the Diuretic Hormone 31 (DH31) Signaling System in the Green Shore Crab, Carcinus maenas.

The functional characterization of crustacean neuropeptides and their cognate receptors has not kept pace with the recent advances in sequence determination and, therefore, our understanding of the physiological roles of neuropeptides in this important arthropod sub-phylum is rather limited. We identified a candidate receptor-ligand pairing for diuretic hormone 31 (DH31) in a neural transcriptome of the crab, Carcinus maenas. In insects, DH31 plays species -specific but central roles in many facets of physiology, including fluid secretion, myoactivity, and gut peristalsis but little is known concerning its functions in crustaceans. The C. maenas DH31 transcript codes for a 147 amino acid prepropeptide, and a single receptor transcript translates to a secretin-like (Class B1) G protein-coupled receptor (GPCR). We used an in vitro aequorin luminescence Ca2+ mobilization assay to demonstrate that this candidate DH31R is activated byCarcinus and insect DH31s in a dose-dependent manner (EC50 15–30 nM). Whole mount immunohistochemical and in situ hybridization localization revealed extensive DH31 expressing neurons throughout the central nervous system, most notably in the abdominal ganglion where large, unpaired cells give rise to medial nerves, which terminate in extensive DH31 immunopositive dendritic fields intimately associated with oesophageal musculature. This system constitutes a large and hitherto undescribed neurohemal area adjacent to key muscle groups associated with the gastric system. DH31 expressing neurons were also seen in the cardiac, commissural, oesophageal, and stomatogastric ganglia and intense labeling was seen in dendrites innervating fore- and hindgut musculature but not with limb muscles. These labeling patterns, together with measurement of DH31R mRNA in the heart and hindgut, prompted us test the effects of DH31 on semi-isolated heart preparations. Cardiac superfusion with peptide evoked increased heart rates (10–100 nM). The neuroanatomical distribution of DH31 and its receptor transcripts, particularly that associated with gastric and cardiac musculature, coupled with the cardio- acceleratory effects of the peptide implicate this peptide in key myoactive roles, likely related to rhythmic coordination.

Upper limb muscle activation during sports video gaming of persons with spinal cord injury

Objective Video gaming as a therapeutic tool has largely been studied within the stroke population with some benefits reported in upper limb motor performance, balance, coordination, and cardiovascular status. To date, muscle activation of upper limb muscles in persons with spinal cord injuries (SCI) has not been studied during video game play. In this paper, we provide descriptive and comparative data for muscle activation and strength during gaming for players with tetraplegia and paraplegia, as well as, compare these results with data from traditional arm exercises (ie, biceps curl and shoulder press) with light weights which are commonly prescribed for a home program. Participants Fourteen individuals with chronic SCI (9 tetraplegia, 5 paraplegia). Design We measured upper limb muscle activation with surface electromyography (EMG) during Wii Sports video game play. Muscle activation was recorded from the playing arm during 4 selected games and normalized to a maximum voluntary contraction (MVC). Outcome measures Heart rate and upper limb motion were recorded simultaneously with EMG. Wilcoxon signed rank tests were used to analyze differences in muscle activation between participants with paraplegia versus tetraplegia and compare gaming with traditional arm exercises with light weights. A Friedman 2-way analysis of variance identified key muscle groups active during game play. Results Overall muscle activation across the games was not different between those with paraplegia and tetraplegia. Heart rate during video game play for tennis and boxing were on average 10 to 20 beats/minute above resting heart rate. The magnitude of EMG was relatively greater for traditional arm exercises with light weights compared with game play. Conclusion The selected Wii games were able to elicit upper extremity muscle activation and elevated heart rates for individuals with SCI that may be used to target therapeutic outcomes.

V12-02 ANALYSIS OF SURGEON BIOMETRICS DURING OPEN AND ROBOTIC RADICAL CYSTECTOMY WITH ELECTROMYOGRAPHY AND MOTION CAPTURE ANALYSIS

You have accessJournal of UrologyImaging Based Techniques & Uroradiology1 Apr 2018V12-02 ANALYSIS OF SURGEON BIOMETRICS DURING OPEN AND ROBOTIC RADICAL CYSTECTOMY WITH ELECTROMYOGRAPHY AND MOTION CAPTURE ANALYSIS Adam Baumgarten, Jeff Robison, John Mayer, Dustin Hardwick, and Trushar Patel Adam BaumgartenAdam Baumgarten More articles by this author , Jeff RobisonJeff Robison More articles by this author , John MayerJohn Mayer More articles by this author , Dustin HardwickDustin Hardwick More articles by this author , and Trushar PatelTrushar Patel More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.3010AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Three published randomized clinical trials have failed to demonstrate a significant advantage for robotics in patients undergoing radical cystectomy compared to open surgery, however, none of these trials have evaluated surgeon performance or preference regarding these procedures. The purpose of this study was to determine feasibility in measuring surgeon physical stress during both open radical cystectomy (ORC) and robotic radical cystectomy (RRC) using real-time motion capture and electromyographic (EMG) analysis. METHODS After IRB approval, a single surgeon who routinely performs both ORC and RRC was recruited to participate in the study. Analysis was done in two patients, one patient who underwent ORC and the other RRC. Exclusion criteria included BMI > 35, history of prior radiation, node-positive disease, and >cT2 disease. The diversion was excluded from this study. The Noraxon® Biomechanical Analysis System version 3.8 was used for data analysis. We used 6 MyoMotion Kinematics Analysis Sensors to quantify the amount of joint and segmental motion of the spine, shoulders, and head. 16 channels of MyoMuscle EMG sensors were used to measure activation levels, patterns, and fatigue characteristics of key muscle groups. Surgeon strength and endurance of the core musculature was assessed with the Prone Static Plank Test (PSPT) and Modified Biering-Sorensen Test (MBST) before and after surgery each surgery. Validated techniques for motion and EMG data collection and processing were used. RESULTS Descriptive analyses were run for 5 stages of the surgeries representing ureteral dissection, posterior dissection, bladder and prostate pedicle dissection, dorsal vein ligation, and lymph node dissection. During ORC, the percentage of time spent in cervical flexion for each stage was 98%, 91.8%, 87.5%, 100%, and 97.1% respectively. During RRC, 100% of the time was spent in cervical flexion for all stages. Activation of key muscle groups for both procedures was examined across all 5 stages and expressed as a percentage of peak activation. The pre and post open surgery MBST was both 25 sec and the PSPT was 68 sec and 48 sec, respectively. The pre and post robotic surgery MBST was 25.1 sec and 32.4 sec, respectively and the PSPT was 59 sec and 51 sec, respectively. CONCLUSIONS We were able to identify meaningful data using motion and EMG analysis during ORC and RRC. Target muscle groups were identified that can be used to conduct a larger study with multiple surgeons to help identify if there is an ergonomic advantage to RRC over traditional ORC. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1236-e1237 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Adam Baumgarten More articles by this author Jeff Robison More articles by this author John Mayer More articles by this author Dustin Hardwick More articles by this author Trushar Patel More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...

Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury.

Traumatic spinal cord injuries (SCIs) affect millions of people worldwide; the majority of whom are in the chronic phase of their injury. Unfortunately, most current treatments target the acute/subacute injury phase as the microenvironment of chronically injured cord consists of a well-established glial scar with inhibitory chondroitin sulfate proteoglycans (CSPGs) which acts as a potent barrier to regeneration. It has been shown that CSPGs can be degraded in vivo by intrathecal Chondroitinase ABC (ChABC) to produce a more permissive environment for regeneration by endogenous cells or transplanted neural stem cells (NSCs) in the subacute phase of injury. Using a translationally-relevant clip-contusion model of cervical spinal cord injury in mice we sought to determine if ChABC pretreatment could modify the harsh chronic microenvironment to enhance subsequent regeneration by induced pluripotent stem cell-derived NSCs (iPS-NSC). Seven weeks after injury—during the chronic phase—we delivered ChABC by intrathecal osmotic pump for one week followed by intraparenchymal iPS-NSC transplant rostral and caudal to the injury epicenter. ChABC administration reduced chronic-injury scar and resulted in significantly improved iPSC-NSC survival with clear differentiation into all three neuroglial lineages. Neurons derived from transplanted cells also formed functional synapses with host circuits on patch clamp analysis. Furthermore, the combined treatment led to recovery in key functional muscle groups including forelimb grip strength and measures of forelimb/hindlimb locomotion assessed by Catwalk. This represents important proof-of-concept data that the chronically injured spinal cord can be ‘unlocked’ by ChABC pretreatment to produce a microenvironment conducive to regenerative iPS-NSC therapy.