Key Micronutrients Research Articles

Impact of iron and manganese nano-metal-oxides on contaminant interaction and fortification potential in agricultural systems – a review

Environmental contextNanominerals are more reactive than bulk minerals, a property that strongly influences the fate of nutrients and contaminants in soils and plants. This review discusses applications of Fe- and Mn-nano-oxides in agricultural systems and their potential to be used as fertiliser and contaminant adsorbents, while addressing potential phytotoxicity. We discuss areas where significant advances are needed, and provide a framework for future work. AbstractRising population growth and increase global food demand have made meeting the demands of food production and security a major challenge worldwide. Nanotechnology is starting to become a viable remediation strategy of interest in farming. Ultimately, it may be used as a sustainability tool in agricultural systems. In these roles, it could be used to increase the efficiency of techniques such as food monitoring, pathogen control, water treatment and targeted delivery of agrochemicals. In addition to these uses, nanoparticles, particularly nano-metal-oxides (NMOs), have been engineered to act as contaminant scavengers and could be applied to a wide range of systems. Numerous studies have investigated the scavenging ability of NMOs, but few have investigated them in this role in the context of agricultural and food systems. Within these systems, however, research has demonstrated the potential of NMOs to increase crop health and yield but few have studied using NMOs as sources of key micronutrients, such as Fe and Mn. In this review, we address previous research that has used Fe- and Mn-NMOs in agricultural systems, particularly the worldwide crop production of the four major staple foods – rice, wheat, maize and soybeans – highlighting their application as fertilisers and sorbents. Fe- and Mn-NMOs are strong candidates for immobilisation of agricultural contaminants in soils and, because they are naturally ubiquitous, they have the potential to be a cost-effective and sustainable technology compared with other remediation strategies.

Nutritional Deficiencies Are Common in Patients with Transfusion-Dependent Thalassemia and Associated with Iron Overload.

Patients with thalassemia are frequently deficient in key micronutrients. Attempts to correct these inadequacies through nutritional supplementation have been met with some success, although disparities between intake and circulating levels continue to be observed. This study employed a convenience sample of 41 well-nourished transfusion dependent patients with thalassemia to identify possible mechanisms behind nutritional deficiencies. Each subject completed a Block 2005© Food Frequency Questionnaire (FFQ), through which macro and micronutrient intake was quantified. Fasting blood was drawn to assess vitamins A, C, D, E, copper, selenium, zinc and hematologic parameters. Dietary intake was found to be inadequate compared to Institute of Medicine (IOM) recommendations for many of the fat-soluble vitamins, as well as calcium and zinc. Circulating deficiencies of vitamins C, D, copper, zinc and γ tocopherol were also present in over 20% of patients. Many individuals who consumed an adequate dietary intake had deficient levels of circulating nutrients, which suggest alternative etiologies of nutrient excretion or loss, in addition to higher micronutrient requirements. Liver iron concentration displayed a significant negative relationship with vitamins C (r=-0.62, p<0.001), E (r=-0.37, p=0.03), and zinc (r=-0.35, p=0.037), indicating that in iron-overloaded patients, these nutrients are either endogenously consumed at higher rates or sequestered within the liver, resulting in a functional nutrient deficiency. While this study identified hepatic iron overload to be a significant cause of nutritional deficits commonly observed in patients with thalassemia, multiple etiologies are simultaneously responsible. In response to these findings, nutritional status should be monitored regularly in at-risk patients with thalassemia, and prophylactically addressed with supplementation or aggressive chelation to avoid associated co-morbidities.

Estimates of Indigenous Food Consumption and Their Contribution to Nutrient Intake in Oraon Tribal Women of Jharkhand, India.

Oraon tribes of India have high levels of undernutrition. Dietary diversification is one of the food-based interventions to ameliorate malnutrition. This study assessed the awareness and availability of indigenous foods and estimated dietary intakes and nutritional status with emphasis on indigenous food consumption among women in the Oraon tribal community in Jharkhand, India. A cross-sectional study with a longitudinal component on dietary intake assessment to capture seasonality. Selected villages in Raidih block of Gumla district of Jharkhand. Reproductive-age Oraon tribal women (N =143). Household and dietary surveys were conducted. A 24-hour dietary recall for 2 consecutive days (repeat surveys in 2 other seasons) and food frequency questionnaire were adminsitered on 1 woman per household. Anthropometric assessments were also carried out. Socioeconomic status, awareness about indigenous foods, dietary intake pattern, and contribution of indigenous food to nutrient intake of Oraon tribal women in the reproductive age-group. Comprehensive awareness about indigenous food resources was present. However, household food security and actual intake of indigenous foods were low. Higher intake of key micronutrients, calcium and iron, was observed among those who consumed indigenous foods. About 40% of the woman had various degrees of chronic energy deficiency. Despite rich knowledge, nutrient-rich indigenous food resources remain underutilized in the Oraon tribal community of Jharkhand, India. Identifying strategies to promote dietary diversity via optimum indigenous food intake could contribute to both food and nutrition security.

Assessment of micronutrients intakes in the Spanish population: a review of the findings from the ANIBES study.

micronutrients are essential compounds present in foods and diets should provide adequate quantities to maintain growth, development and metabolic functions in men. to review the adequacy to micronutrient recommendations amongst the population from the ANIBES study. published data from the ANIBES Study was reviewed to assess intakes in relation to the Recommended Dietary Intakes (RDI) for each age group including total, plausible and non-plausible reporters. throughout all age groups, folates and vitamin D were the vitamins with the lowest proportion of subjects having intakes above 80% the RDI. Zinc intake was lower in children, adults and the elderly but not in adolescents. Nevertheless, vitamin D consumption increased with age. our results show inadequate intakes for at least three key micronutrients across all age groups. Authorities should promote nationwide nutritional policies to address unbalanced diets focusing on reaching vulnerable populations in order to overcome this major public health problem.

The Impact of Genetic Changes during Crop Domestication

Humans have domesticated hundreds of plant and animal species as sources of food, fiber, forage, and tools over the past 12,000 years, with manifold effects on both human society and the genetic structure of the domesticated species. The outcomes of crop domestication were shaped by selection driven by human preferences, cultivation practices, and agricultural environments, as well as other population genetic processes flowing from the ensuing reduction in effective population size. It is obvious that any selection imposes a reduction of diversity, favoring preferred genotypes, such as nonshattering seeds or increased palatability. Furthermore, agricultural practices greatly reduced effective population sizes of crops, allowing genetic drift to alter genotype frequencies. Current advances in molecular technologies, particularly of genome sequencing, provide evidence of human selection acting on numerous loci during and after crop domestication. Population-level molecular analyses also enable us to clarify the demographic histories of the domestication process itself, which, together with expanded archaeological studies, can illuminate the origins of crops. Domesticated plant species are found in 160 taxonomic families. Approximately 2500 species have undergone some degree of domestication, and 250 species are considered to be fully domesticated. The evolutionary trajectory from wild to crop species is a complex process. Archaeological records suggest that there was a period of predomestication cultivation while humans first began the deliberate planting of wild stands that had favorable traits. Later, crops likely diversified as they were grown in new areas, sometimes beyond the climatic niche of their wild relatives. However, the speed and level of human intentionality during domestication remains a topic of active discussion. These processes led to the so-called domestication syndrome, that is, a group of traits that can arise through human preferences for ease of harvest and growth advantages under human propagation. These traits included reduced dispersal ability of seeds and fruits, changes to plant structure, and changes to plant defensive characteristics and palatability. Domestication implies the action of selective sweeps on standing genetic variation, as well as new genetic variation introduced via mutation or introgression. Furthermore, genetic bottlenecks during domestication or during founding events as crops moved away from their centers of origin may have further altered gene pools. To date, a few hundred genes and loci have been identified by classical genetic and association mapping as targets of domestication and postdomestication divergence. However, only a few of these have been characterized, and for even fewer is the role of the wild-type allele in natural populations understood. After domestication, only favorable haplotypes are retained around selected genes, which creates a genetic valley with extremely low genetic diversity. These “selective sweeps” can allow mildly deleterious alleles to come to fixation and may create a genetic load in the cultivated gene pool. Although the population-wide genomic consequences of domestication offer several predictions for levels of the genetic diversity in crops, our understanding of how this diversity corresponds to nutritional aspects of crops is not well understood. Many studies have found that modern cultivars have lower levels of key micronutrients and vitamins. We suspect that selection for palatability and increased yield at domestication and during postdomestication divergence exacerbated the low nutrient levels of many crops, although relatively little work has examined this question. Lack of diversity in modern germplasm may further limit our capacity to breed for higher nutrient levels, although little effort has gone into this beyond a handful of staple crops. This is an area where an understanding of domestication across many crop taxa may provide the necessary insight for breeding more nutritious crops in a rapidly changing world.

Copper and copper nanoparticles: role in management of insect-pests and pathogenic microbes

Abstract Crop losses mainly occur due to biotic factors, which include soil-borne phytopathogens, insect pests, parasites, and predators. The major loss of food in the food industry is due to its spoilage by various microorganisms. With advancement in nanotechnology, the use of nanoparticles in food and agriculture crop yield can be improved. In this context, copper nanoparticles (CuNPs) have attracted a great deal of attention from all over the world due to their broad-spectrum antimicrobial activity. Copper is one of the key micronutrients, which plays an important role in growth and development of plants. CuNP-based fertilizer and herbicide can be used in agriculture. The small size of CuNPs facilitates their easy absorption by the plants. CuNPs can be promisingly used in the food packaging to avoid the growth of food spoilage microorganisms. The use of CuNP-based agar packaging materials has substantial potential to increase the shelf-life of food. The present review focuses on the application of Cu and CuNPs in food and agriculture. Moreover, antimicrobial and pesticidal properties of CuNPs are also discussed.

Placental adaptations to micronutrient dysregulation in the programming of chronic disease.

Poor nutrition during pregnancy is known to impair foetal development and increase the risk of chronic disease in offspring. Both macronutrients and micronutrients are required for a healthy pregnancy although significantly less is understood about the role of micronutrients in the programming of chronic disease. This is despite the fact that modern calorie rich diets are often also deficient in key micronutrients. The importance of micronutrients in gestational disorders is clearly understood but how they impact long term disease in humans requires further investigation. In contrast, animal studies have demonstrated how diets high or low in specific micronutrients influence offspring physiology. Many of these studies highlight the importance of the placenta in determining disease risk. This review will explore the effects of individual vitamins, minerals and trace elements on offspring disease outcomes and discuss several key placental adaptations that are affected by multiple micronutrients. These placental adaptations include micronutrient induced dysregulation of oxidative stress, altered methyl donor availability and its impact on epigenetic mechanisms as well as endocrine dysfunction. Critical gaps in our current knowledge and the relative importance of different micronutrients at different gestational ages will also be highlighted. Finally, this review will discuss the need for further studies to characterise the micronutrient status of Australian women of reproductive age and correlate micronutrient status to placental adaptations, pregnancy complications and offspring disease.

Comparison Of Dietary Habits Between Volunteer Firefighters And Non-firefighters

As the global burden of cardiovascular disease (CVD) rises, public health-related interventions aimed at prevention have gained increased attention. Physicians and public health officials may be unaware that CVD or cardiac events are related to more than half of the line-of-duty deaths in firefighters (FF). Diet is one of the main modifiable CVD risk factors, yet poor diet and the risk factors it contributes to, including obesity, continue to be an issue as the prevalence of obesity is high in FF. Dietary patterns can also influence other risk factors like blood pressure, lipid levels, body composition and glucose metabolism. However, healthy diets are not always feasible for FF, due to the fast-paced unpredictable nature of work, and thus FF often rely on quick meals that may not be nutritiously optimal. Limited research has examined FF dietary intake and preferences. PURPOSE: To examine the dietary habits of local volunteer FF and compare these to adult non-FF in the area. METHODS: 76 adults (36 FF, 37.0 ±11 years, BMI 30.4 ±5.7 kg/m2; 40 non-FF, 30.6 ±11 years, BMI 28.3 ±5.7 kg/m2) were studied. All participants completed a 3-day dietary recall, and had height and weight measured. Three-day diet recalls were obtained from volunteer FF who attended dietary workshops in their firehouse and from non-FF adults in the area who were interested to find out their dietary habits. Data was analyzed using Diet Analysis Plus. RESULTS: Macronutrient composition of the diets were similar. The FF average diet was 2037.9 ±597.3 calories; including 34.8% fat, 46.0% carbohydrates, and 17.8% protein. The average diet for non-FF adults was 2185.7 ±405.9 calories; including 34.1% fat, 48.6% carbohydrates, and 17.8% protein. FF had significantly lower levels of vitamin B-6 (1.7 ±0.9 vs 2.3 ±1.2 mg), folate (498.3 ±253 vs 685.7 ±375 μg), and vitamin C (50.8 ±48.5 vs 111.9 ±87.8 mg) intake compared to non-FF, respectively, p<0.05. FF diets were lacking in several key micronutrients, including calcium (961.8 ± 410 mg), magnesium (227.1 ±138mg), potassium (2177.7 ± 1059 mg), and vitamin D (4.2 ±4.6 μg). For these, >90% of the FF diets did not meet recommended levels. CONCLUSION: These data suggests that volunteer FF exhibit deficiencies in several micronutrients and may benefit from diets that encourage increased consumption of fruits and vegetables.

Improving food-system efficiency and environmental conservation using agricultural biodiversity in Busia County: a pilot study

BackgroundDespite the abundance of edible biodiversity, both wild and cultivated, malnutrition and food insecurity persist in Busia County, Kenya, where poverty indices range from 63% to 74% and 25% of children younger than 5 years are stunted, 11% are underweight, and 4% are thin for their age. Much of this biodiversity, used in traditional food preparations, has the potential to provide access to key micronutrients for healthy and balanced diets and to act as an important source of community resilience to climate change and economic turbulence. Yet, low consumer awareness of the value of local biodiversity, poorly developed value chains, and negative perceptions of traditional foods have led to the disappearance of many nutrient-rich species and the shift to unhealthy diets. We aimed to show that heightened knowledge of the value of biodiversity and improved value-chain efficiencies can help to conserve biodiversity and improve local food systems. MethodsWe developed a farmer business school model and provided training to 25 farmer groups across seven sub-counties in Busia County, Kenya, on the sustainable production of traditional vegetables, post-harvest handling, contract farming, nutrition, and value addition. We also analysed selected species for nutritional content, tested a food procurement model supporting market linkages between farmers and local institutions, and carried out nutrition education activities to improve the capacity of schools and clinics to incorporate traditional foods into meals. FindingsWe found that traditional vegetables were rich in iron—for example, cowpea leaves contained 17 times more iron than did kales. After making the nutritional data available to all value chain actors during implementation of the food procurement model, we recorded a 12% increase in the number of households cultivating local biodiversity, both for household consumption and off-farm sales, along with a 75% increase in the plot size devoted to traditional vegetable cultivation. Furthermore, household incomes increased by a mean of 47% (SD 30) as a result of direct links with institutional markets. The effects of increased market linkages on education, economic, and health benefits will be measured in a second phase of the project to start in 2018. InterpretationThe project has positively affected the abundance, composition, and distribution of species and revived interest in local food biodiversity, in addition to producing benefits around diverse diets. Experience in implementing the Busia model has been used to inform global policies that aim to mainstream biodiversity in sustainable food systems using public procurement, particularly schools, as a platform for improving nutrition. Nationally, a biodiversity policy was developed for Busia County that recognised the importance of local biodiversity, including for improved livelihoods, community resilience, and health and nutrition. FundingGlobal Environment Facility, Australian Centre for International Agricultural Research, and the MacArthur Foundation.

Nutritionally Optimized, Culturally Acceptable, Cost-Minimized Diets for Low Income Ghanaian Families Using Linear Programming.

The Ghanaian population suffers from a double burden of malnutrition. Cost of food is considered a barrier to achieving a health-promoting diet. Food prices were collected in major cities and in rural areas in southern Ghana. Linear programming (LP) was used to calculate nutritionally optimized diets (food baskets (FBs)) for a low-income Ghanaian family of four that fulfilled energy and nutrient recommendations in both rural and urban settings. Calculations included implementing cultural acceptability for families living in extreme and moderate poverty (food budget under USD 1.9 and 3.1 per day respectively). Energy-appropriate FBs minimized for cost, following Food Balance Sheets (FBS), lacked key micronutrients such as iodine, vitamin B12 and iron for the mothers. Nutritionally adequate FBs were achieved in all settings when optimizing for a diet cheaper than USD 3.1. However, when delimiting cost to USD 1.9 in rural areas, wild foods had to be included in order to meet nutritional adequacy. Optimization suggested to reduce roots, tubers and fruits and to increase cereals, vegetables and oil-bearing crops compared with FBS. LP is a useful tool to design culturally acceptable diets at minimum cost for low-income Ghanaian families to help advise national authorities how to overcome the double burden of malnutrition.

Assessing national nutrition security: The UK reliance on imports to meet population energy and nutrient recommendations.

Nutrition security describes the adequacy of the food supply to meet not only energy but also macronutrient and micronutrient requirements for the population. The aim of this study was to develop a method to assess trends in national nutrition security and the contribution of imports to nutrition security, using the UK as a case study. Food supply data from FAO food balance sheets and national food composition tables were used to estimate the nutrient content of domestically produced food, imported food and exported food. Nutrition security was defined as the total nutrient supply (domestic production, minus exports, plus imports) to meet population-level nutrient requirements. The results showed that the UK was nutrition secure over the period 1961–2011 for energy, macronutrients and key micronutrients, with the exception of total carbohydrates and fibre, which may be due to the loss of fibre incurred by processing cereals into refined products. The supply of protein exceeded population requirements and could be met with domestic production alone. Even excluding all meat there was sufficient protein for population requirements. The supply of total fat, saturated fat and sugar considerably exceeded the current dietary recommendation. As regards nutrition security in 2010, the UK was reliant on imported foods to meet energy, fibre, total carbohydrate, iron, zinc and vitamin A requirements. This analysis demonstrates the importance of including nutrients other than energy to determine the adequacy of the food supply. The methodology also provides an alternative perspective on food security and self-sufficiency by assessing the dependency on imports to meet population level nutritional requirements.

English

Adequate dietary intake is important in achieving optimal nutrition and health for people before and during treatment of HIV. Inadequate nutrition causes health issues and fatalities among prisoners. Thus, this study assesses dietary intake and factors affecting food service among male prisoners living with HIV at selected prisons in Kenya. A cross sectional analytical study design was adopted on a sample of 113 male prisoners living with HIV, randomly sampled from 4 prisons. Data collection tools included a structured questionnaire used to collect demographic, 24 h recall and food frequency data. During data analysis, 24 h recall data was analyzed using Nutri-survey software, and further analysis via SPSS software. Results revealed that slightly more than half the prisoners (50.4%) were aged 36-53 years. Primary education was attained by 60.2% and secondary education by 21.2%. Mean dietary intake for macronutrients was: Energy (1815±218 Kcal), Protein (56±12 g), fat (32±6 g), Carbohydrates (322±45 g), Fiber (41±23 g) and PUFA (8±1 g). None attained Recommended Daily Allowances (RDA) for energy, fat and PUFAs. Mean key micronutrients were: Vitamin A (1195.1±812.7), Vitamin B6 (1.9±0.9), Vitamin C (55.7±18.4), Iron (10.2±2.7), Magnesium (488.1±152.3) and Zinc (13.9±6.7). None met RDA for Iron. Therefore, provision of a nutritionally balanced diet in prisons can ensure nutrients adequacy. Key words: Dietary intake, food service, prisoners living with HIV.

Effects of Carpobrotus edulis invasion on main litter and soil characteristics in backdune and rocky coastal habitats with oceanic climate

Carpobrotus edulis invades coastal areas throughout the world, decreasing plant diversity and hampering restoration efforts by changing soil properties. Some of its effects on soils are known but there is a knowledge gap about the effects in rocky areas and micronutrients that we aimed to fill for dunes and rocky habitats with temperate-humid climate. We compared invaded vs non-invaded paired plots in two dune and two rocky areas by measuring 18 variables in litter and 24 in soils (0–5 and 5–10 cm layers). Invasion effects increased with the accumulated alien necromass, decreased with soil depth and are substrate-dependent: soil pH, Al, Fe and P increased in dunes, while these variables and Mg, Cu and Zn decreased in rocky sites. Carpobrotus necromass is richer in Mg and Ca and poorer in Al, Co, Cu, Fe, Ni and Zn than native necromass. Invader effects on soils are largely mediated by its necromass, which has contrasting characteristics with the autochthonous necromass. Carpobrotus edulis ability to discriminate against Al uptake, while favouring Mg and Ca uptake, and its lower requirement (or higher resorption) of key micronutrients (Co, Cu, Fe, Ni, Zn) than native vegetation could partly explain its invasiveness.

Dietary patterns and obesity in preschool children in Australia: a cross-sectional study.

Dietary patterns have been linked to the risk of obesity in adults but little is known about such a link in young children. To examine the association between dietary patterns, nutrient intake and obesity in a representative population of preschool children in Australia. Dietary intake was assessed using a 3-day weighed food diary. Dietary patterns were identified by factor analysis. Children were classified as overweight or obesity if their BMI z-score was between the 85th-95th percentiles or was above the 95th percentile, respectively. Three dietary patterns were identified. The 'Traditional' pattern was characterised by grains, fruit, vegetables, and red meat. The 'Processed' pattern was characterised by processed meats, snack foods and confectionary. The 'Health conscious' pattern was characterised by eggs, fish, polyunsaturated margarines and low fat dairy products. The 'Traditional' pattern was positively associated with protein and zinc intake while the 'Processed' pattern was inversely associated. Both patterns were inversely associated with calcium intake. No associations were found between the 'Health conscious' pattern and macronutrients and key micronutrients intakes. The 'Traditional' pattern was positively associated with obesity but the association became non-significant after adjustment for energy and protein intake. No association was observed between the other two dietary patterns and weight status. In this cross-sectional study, dietary patterns were not associated with obesity. Longitudinal follow up will help to better understand the relationship between dietary patterns in early childhood and the risk of obesity later in life.

A review of the landscape and approach for biofortification initiatives in Zimbabwe

Micronutrient deficiencies “hidden hunger” can result in stunting, blindness, mental retardation, learning disabilities, low work capacity, and even premature death. Biofortification is an agro-based intervention designed to increase the content of key micronutrients in staple crops in order to correct or prevent micronutrient deficiencies primarily among the rural poor who are vulnerable to “hidden hunger”. This paper summarises a review of the current issues and recommendations to scaling up biofortification initiatives in Zimbabwe. The biofortification initiatives; vitamin A orange maize, iron-zinc beans, zinc pearl millet and Orange Fleshed Sweet Potatoes (OFSP). Although, the country has the necessary policy frameworks and multi-sectoral platforms to accelerate the use of biofortified crops, the current initiatives are still in the pilot stage with fragmented efforts by stakeholders. This is the key challenge that will stale the efforts to scale up to national level. Interestingly, the government led food-based approach “dietary diversification” provides an opportunity to integrate and scaling up of biofortification initiatives in Zimbabwe. However, there is need for a comprehensive implementation plan within the existing policy and institutional frameworks. In this paper we raised some questions that will need to be addressed to enable successful scaling up of biofortification in the Zimbabwean context. Addressing these questions will help create a supportive policy framework and assist Zimbabwe to identify specific impact pathways for biofortification.

Excess iron: considerations related to development and early growth

What effects might arise from early life exposures to high iron? This review considers the specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and identifies gaps in our knowledge of what molecular damage may be incurred by oxidative stress that is imparted by high iron status in early life. Specific areas to enhance research on this topic include the following: longitudinal behavioral studies of children to test associations between iron exposures and mood, emotion, cognition, and memory; animal studies to determine epigenetic changes that reprogram brain development and metabolic changes in early life that could be followed through the life course; and the establishment of human epigenetic markers of iron exposures and oxidative stress that could be monitored for early origins of adult chronic diseases. In addition, efforts to understand how iron exposure influences stem cell biology could be enhanced by establishing platforms to collect biological specimens, including umbilical cord blood and amniotic fluid, to be made available to the research community. At the molecular level, there is a need to better understand stress erythropoiesis and changes in iron metabolism during pregnancy and development, especially with respect to regulatory control under high iron conditions that might promote ineffective erythropoiesis and iron-loading anemia. These investigations should focus not only on factors such as hepcidin and erythroferrone but should also include newly identified interactions between transferrin receptor-2 and the erythropoietin receptor. Finally, despite our understanding that several key micronutrients (e.g., vitamin A, copper, manganese, and zinc) support iron's function in erythropoiesis, how these nutrients interact remains, to our knowledge, unknown. It is necessary to consider many factors when formulating recommendations on iron supplementation.

Opportunities and hurdles of edible insects for food and feed

AbstractEntomophagy, the consumption of insects, is promoted as an alternative sustainable source of protein for humans and animals. Seminal literature highlights predominantly the benefits, but with limited empirical support and evaluation. We highlight the historical significance of entomophagy by humans and key opportunities and hurdles identified by research to date, paying particular attention to research gaps. It is known that insects present a nutritional opportunity, being generally high in protein and key micronutrients, but it is unclear how their nutritional quality is influenced by what they are fed. Research indicates that, in ideal conditions, insects have a smaller environmental impact than more traditional Western forms of animal protein; less known is how to scale up insect production while maintaining these environmental benefits. Studies overall show that insects could make valuable economic and nutritional contributions to the food or feed systems, but there are no clear regulations in place to bring insects into such supply systems. Future research needs to examine how the nutritional value of insects can be managed systematically, establish clear processing and storage methodology, define rearing practices and implement regulations with regard to food and feed safety. Each of these aspects should be considered within the specifics of concrete supply and value chains, depending on whether insects are intended for food or for feed, to ensure insects are a sound economic, nutritional and sustainable protein alternative – not just a more expensive version of poultry for food, or soya for feed.

Simultaneous assessment of iodine, iron, vitamin A, malarial antigenemia, and inflammation status biomarkers via a multiplex immunoassay method on a population of pregnant women from Niger.

Deficiencies of vitamin A, iron, and iodine are major public health concerns in many low- and middle-income countries, but information on their status in populations is often lacking due to high costs and logistical challenges associated with assessing micronutrient status. Accurate, user-friendly, and low-cost analytical tools are needed to allow large-scale population surveys on micronutrient status. We present the expansion of a 7-plex protein microarray tool for the simultaneous measurement of up to seven biomarkers with relevance to the assessment of the key micronutrients iron, iodine, and vitamin A, and inflammation and malaria biomarkers: α-1-acid glycoprotein, C-reactive protein, ferritin, retinol binding protein 4, soluble transferrin receptor, thyroglobulin, and histidine-rich protein II. Assay performance was assessed using international reference standards and then verified by comparing the multiplexed and conventional immunoassay results on a training panel of plasma samples collected from US adults. These data were used to assign nominal concentrations to the calibrators of the assay to further improve performance which was then assessed by interrogating plasma samples from a cohort of pregnant women from Niger. The correlation between assays for each biomarker measured from this cohort was typically good, with the exception of thyroglobulin, and the sensitivity ranged from 74% to 93%, and specificity from 81% to 98%. The 7-Plex micronutrient assay has the potential for use as an affordable tool for population surveillance of vitamin A, iron, and iodine deficiencies as well as falciparum malarial parasitemia infectivity and inflammation. The assay is easy-to-use, requires minimal sample volume, and is scalable, rapid, and accurate—needing only a low-cost reader and basic equipment present in most reference laboratory settings and so may be employed by low and middle income countries for micronutrient surveillance to inform on status in key populations. Micronutrient deficiencies including iron, iodine, and vitamin A affect a significant portion of the world’s population. Efforts to assess the prevalence of these deficiencies in vulnerable populations are challenging, partly due to measurement tools that are inadequate for assessing multiple micronutrients in large-scale population surveys. We have developed a 7-plex immunoassay for the simultaneous measurement of seven biomarkers relevant to assessing iodine, iron, and vitamin A status, inflammation and Plasmodium falciparum parasitemia by measuring levels of thyroglobulin, ferritin, soluble transferrin receptor, retinol binding protein 4, α-1-acid glycoprotein, C-reactive protein, and histidine-rich protein II. This 7-plex immunoassay technique has potential as a rapid and effective tool for use in large-scale surveys and assessments of nutrition intervention programs in low- and middle-income countries.

Impact of potato processing on nutrients, phytochemicals, and human health

ABSTRACTPotatoes (Solanum tuberosum) are an important global crop that can be transformed into many products impacting several health dimensions ranging from undernutrition, food security and disease prevention to issues of overnutrition including obesity, diabetes, heart disease. Processed potato products are typically categorized as high fat and sodium foods, as well as being classified as a significant source of carbohydrate, in the form of starch. Conversely, potato products are less known for their contribution of key micronutrients (vitamin C, potassium, magnesium), fiber, and phytochemicals (phenolics and carotenoids). More recent insight into the nutritional value of potatoes and the potential of potato phytochemicals to modulate oxidative and inflammatory stress as well as the potential to alter glycemic response has resulted in increased interest in strategies to improve and leverage the nutritional quality of processed potatoes. This review summarizes critical information on nutritional profiles of potatoes and their processed products and describes the state of the science relative to the influence of in-home and common commercial processing on nutritional quality and potential impacts on human health.

Household food insecurity is associated with a higher burden of obesity and risk of dietary inadequacies among mothers in Beirut, Lebanon

BackgroundMixed evidence exists with respect to the association between household food insecurity (HFIS) and obesity in low-to-middle income countries (LMICs), particularly among women. This study aimed to measure socioeconomic correlates of HFIS and explores its association with dietary intake and odds of obesity among mothers in Lebanon, a middle-income country undergoing nutrition transition.MethodsA cross-sectional study was conducted among a representative sample of households (n = 378) in Beirut, Lebanon. Surveys were completed with mothers of children <18 years. HFIS was measured using a locally-validated, Arabic-translated Household Food Insecurity Access Scale (HFIAS). Dietary intake was assessed using the multiple pass 24-h recall method. Associations between HFIS (food vs food insecure) and socio-demographic characteristics were reported using crude and adjusted odds ratios. The odds of consuming <2/3rd Dietary Reference Intakes (DRIs) for nutrients among mothers from food secure and food insecure households were explored. In addition, logistic regression analyses were conducted to explore the association of HFIS with obesity (BMI ≥ 30 kg/m2) and at-risk waist circumference (WC ≥ 80 cm) among mothers.ResultsHFIS was found among 50% of study sample and was inversely associated with household income and mother’s educational level, even after adjusting for other socioeconomic variables (p < 0.01). Mothers in food insecure households reported consuming significantly less dairy products, fruits, and nuts yet more breads and sweets; and they had higher odds of consuming <2/3rd the DRI’s for key micronutrients (potassium, folate, and vitamin C) compared to secure ones. Adjusting for socioeconomic correlates, food insecure mothers had 1.73 odds of obesity (95% CI: 1.02–2.92) compared to food secure mothers.ConclusionsHigh HFIS prevalence was reported among urban Lebanese households. Mothers from food insecure households had a high risk of dietary inadequacy and obesity. Adequate evidence-based public health strategies are needed to reduce the vulnerability of mothers to food insecurity in LMIC settings and alleviate their risk of a high burden of nutrient insecurity and obesity.