The principle problem in multiresponse nonparametric regression model is how we estimate the regression functions which draw association between some dependent (response) variables and some independent (predictor) variables where there are correlations between responses. There are many techniques used to estimate the regression function. Two of them are spline and kernel smoothing techniques. Speaking about smoothing techniques, not only in uniresponse spline and kernel nonparametric regression models but also in multiresponse spline and kernel nonparametric regression models, the estimations of regression functions depend on smoothing parameters. In the privious researches the covariance matrices were assumed to be known. Matrix of covariance is not assumed known in this research. The goals of this research are selecting of optimal smoothing parameters for the model we consider through spline and kernel smoothing techniques. Optimal smoothing parameters can be obtained by taking the solution to generalized cross validation (GCV) optimization problem. The obtained results of this research are the optimal smoothing parameter for smoothing spline estimator approach and the optimal smoothing parameter namely optimal bandwidth for kernel estimator approach.
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