Kaurane Derivatives Research Articles

Perydiscolic acid, a germacranolide from Perymenium species

The chemical investigation of two Perymenium species afforded, in addition to known kaurane derivatives and 14-acetoxydesacetyl laurenobiolide, a new sesquiterpene, perydiscolic acid. The structures were elucidated by spectroscopic methods and a few chemical transformations.

Two further 6,12- cis-germacranolides from Montanoa tomentosa subsp. xanthiifolia

The aerial parts of Montanoa tomentosa subsp. xanthiifolia gave two further 6,12- cis-germacranolides while the roots contained large amounts of kaurane derivatives.

Synthesis of Kaurane Derivatives with an Oxygen Function in Ring A

A total synthesis of some kaurane derivatives with an oxygen function in ring A was accomplished. They are potential intermediates for the synthesis of highly oxygenated diterpenes such as grayanotoxins.

Synthesis of Kaurane Derivatives with an Oxygen Function in Ring A

Synthesis of Kaurane Derivatives with an Oxygen Function in Ring A

NMR studies of kaurane derivatives

NMR studies of kaurane derivatives

The chemistry of the Euphorbiaceae. XV. Further diterpenes from Ricinocarpus stylosus: 1a, 19-diliydroxy-16a-( - )-kauran-17-oic acid

Another two diterpenes based on the (-)-kaurane skeleton have been isolated from Ricinocarpus stylosus. One is the known 16,17-dihydroxy-16β-(-)-kauran-19-oic acid (IIb) and the other has been shown to be lα,l9-dihydroxy-16α-(-)-kauran-17-oic acid (IVa). The N.M.R. spectra of various kaurane derivatives in chloroform and benzene solutions are compared.