We applied an advanced chaos-geometric approach to analysis, modeling, forecasting and processing the time series of the air pollutants (NO2) concentrations in an atmosphere of the industrial cities (regions). The approach includes such advanced non-linear analysis and a chaos theory methods such as a multifractal approach, correlation integral algorithm, the Lyapunov’s exponents and Kolmogorov entropy analysis, a power spectrum analysis, prediction models with neural networks blocks etc. The dynamical and topological invariants (including the Lyapunov’s exponents spectrum, Kaplan-Yorke dimension, Kolmogorov entropy etc) for the air pollutants (NO2) concentrations time series in an atmosphere of the industrial cities are computed. Our study has shown an existence of a deterministic chaos in the atmospheric pollutants fluctuations dynamics. It is presented an effective prediction model for description of the temporal evolutionary dynamics of the air pollutants concentration in atmosphere of the industrial city.