The biosorbents from different fruit waste such as tomato waste and apple juice residue were prepared and had been investigated in removing of Pb(II) ion from the aqueous solution under optimized conditions. All fruit waste materials were activated by NaOH in room temperature. The synthesized biosorbents were characterized by FT-IR, SEM, and surface area analyzer. Effects of contact time, the pH of the solution, and sorbent dosage on the Pb(II) removal process had been optimized. Freundlich isotherm matched the experimental data than Langmuir isotherm model. A kinetic study presented that Pb(II) sorption follows the pseudo-second-order kinetics. The Pb(II) removal capacity of tomato waste and apple juice residue biosorbents are 152 and 108 mg/g, respectively. The results showed that biosorbents have the potential capacity to remove the lead, which further strongly increases after its activation.