This work is devoted to the development of a biocompatible polymer-composite material based on polyetheretherketone (PEEK) with the addition of a reinforcing phase - hexagonal boron nitride (h-BN). This composite is considered as a promising material for use in medicine, for example, for the manufacture of components of a hip joint endoprosthesis or plates for fi xing fractures.The paper considers the properties of the initial components of the material under development, studies the data on the biocompatibility of materials based on PEEK and their application in medicine, in particular, in orthopedics. Experimental data were used to study the eff ect of diff erent concentrations of h-BN on the properties of the composite. In the course of the work, the morphology and size of the particles of the starting materials, as well as the surface of the obtained samples after testing, were investigated, the dependences of the deformation-strength, tribological and biological characteristics on the composition of the composite were obtained and analyzed. A brief analysis of the results obtained is presented, as well as promising directions for the application of the developed material in orthopedics are proposed.