Virtual power plant (VPP), as a new generation of intelligent control technology integrating multi-link resources of “source-load-storage”, can break regional restrictions and realize energy interconnection and sharing in wide area. In order to utilize multi-energy synthetically and efficiently and promote low carbon energy development, the natural gas production and consumption system is built and reasonably regulated, which is composed of carbon capture unit, power to gas (P2G), manure treatment system (MTS), combined heat and power (CHP) unit and gas fired boiler (GB). P2G uses the captured CO2 as raw material to meet the natural gas demand of CHP and GB together with MTS. In order to deal with the difference of “source load” resources of VPP in the same region and solve the problem of power real-time balance caused by the fluctuation of distributed renewable energy (DRE), the multi-system and multi-unit coordinated operation framework is constructed. Based on the shiftable load characteristics of carbon capture power consumption and flue gas treatment power consumption, the fluctuation of renewable energy output power can be stabilized, and the flexible utilization of wind turbine and photovoltaic can be indirectly realized. Internal energy mutual benefit between VPP regions is priced independently to encourage multiple regions of VPP to participate in the joint scheduling. Aiming at maximization of the operation benefit, a VPP optimal scheduling model of energy sharing and interaction among multiple regions is established, and a coordinated optimal scheduling strategy of distributed energy multiple regions in VPP is proposed. In view of the characteristics of the above model, such as high-dimensional, nonlinear and difficult to solve, the populational variation basis vector is introduced into the compound differential evolution algorithm to solve the model. The simulation results show that the proposed model and method can achieve the coordinated and optimal dispatch of power and heat energy between regions in multiple regions VPP, improve the capacity of renewable energy power utilization, reduce the power curtailment cost of WT and PV by 82%, reduce the carbon emission of VPP, increase the carbon trading revenue by 75%, and increase the operation income of VPP by 9%.