Joint Research Project Research Articles

Local Migration Regimes in Rural Areas: The Example of Refugee Reception in Saxony, Germany

The reception of asylum seekers has challenged municipalities and their populations across Europe in recent years: Many rural villages and small and mid-sized towns had little prior experience with large numbers of asylum seekers. The housing of refugees constitutes one of the most controversial arenas and challenges for local communities within the reception process.
 This paper sheds light on rural case studies using the perspective of migration regimes. Local Migration Regimes constitute arenas of migration-related processes including actors, practices, and negotiations at different scales. The analysis covers four rural municipalities (two villages, two towns) from two Saxonian counties in Germany. All cases have different strategies for accommodating migrants but all can be seen as post-socialist immigration societies. The findings show that the issue of reception and housing is seen as a recurrent and contested local field of conflict and cooperation in the rural case sites. The regime lens highlights the strong dependencies but also fragmentation between different levels (national, regional, and supra-local). Housing practices and strategies for refugees reflect local discourses and contribute to the social and spatial production of migration. I argue, that the regime lens contributes to an interdisciplinary understanding of local settings, acknowledges spatial and social structures but challenges empirical field work and data sets. This empirical research is based on qualitative interviews, media articles, and documents from rural counties in Germany and was conducted within the joint research project “Future for Refugees in Rural Regions of Germany”.
 * This article belongs to a special issue on "Refugee Migration to Europe – Challenges and Potentials for Cities and Regions".

Relationship between early-career collaboration among researchers and future funding success in Japanese academia.

Academia is becoming more and more competitive, especially for young scientists, so it is important to understand the factors that affect success in academic careers. To survive in academia, it is crucial to obtain research funding. Previous studies have investigated factors that affect the funding success of researchers. In this paper, we focus on research collaboration structure as a factor affecting funding success. More specifically, we investigate the effects of participation in joint research projects, number of joint research projects, and centrality in the collaborative network on the future funding success of junior researchers in Japan. Our results show that participation in joint research projects and the number of such projects significantly affect the future funding success of junior researchers. Furthermore, the median number of years of funding received by researchers involved in joint research projects was found to be about 1.5 times greater than that of researchers not involved in joint research projects, and the average amount of research funding received after 10 years is about 2-4 times more, suggesting that researchers with collaboration ties with other researchers in the early stages of their career tend to be more successful in the future.

IsoTag™AAV: an innovative, scalable & non-chromatographic method for streamlined AAV manufacturing.

Demand for gene therapies capable of treating previously inaccessible targets has risen precipitously in the past decade. Adeno-associated viruses (AAVs) are the preferred vector for gene delivery because of their favorable safety profile and tissue tropism, but they have significant manufacturing challenges, with end-to-end yields as low as 10-30%. To combat these low yields, we developed IsoTag™AAV, a novel purification technology for AAV that is a departure from the chromatographic paradigm in downstream processing. This proprietary technology uses a self-scaffolding recombinant protein reagent that can improve manufacturing yields. It enables purification by cost-effective and scalable filtration processes and improves product quality with minimal optimization. Herein, we describe the development of IsoTag™AAV, provide a head-to-head comparison to industry-leading affinity chromatography (evaluation carried out through a joint research project with Capsida Biotherapeutics), and demonstrate how it can reduce cost of goods for a clinical AAV program by 25%.

ESMO Designated Centres of Integrated Oncology and Palliative Care (ESMO DCs): education, research and programme development survey

The European Society for Medical Oncology (ESMO) Designated Centres (DCs) of Integrated Oncology and Palliative Care is an incentive programme established in 2003 aiming to improve the integration of oncology and palliative care services provided by oncologists and oncology centres worldwide. Currently, the ESMO DCs programme has over 250 centres accredited from 54 countries worldwide, in all six world regions. To evaluate how ESMO can support centres to improve programme development, education and research and vice versa what each single centre can do to improve in these areas, we developed a survey which was shared with all active centres. Two hundred and seven ESMO DCs representing 44 countries were invited to participate. We used content analysis to identify response categories using a stepwise approach. After reviewing and coding all responses to each question separately, they were placed into categories, counted and labelled. Of the 207 centres that were invited to participate, 146 centres started the survey, representing 43 countries. Five overarching topics were identified. They included (i) joint events and educational activities; (ii) sharing of materials and defining common standards; (iii) sharing of experiences, scientific knowledge and expertise; (iv) research collaboration; and (v) ESMO support. Respondents were willing to support the ESMO DC community group in all topics and were also asking ESMO to support their centres in these issues in the future. The study showed that the ESMO DCs are willing to provide support to improve education, research and programme development. They are also eager to contribute and collaborate amongst each other, but also request ESMO to offer advice and help to improve these issues in the DCs. In the future, facilitation of joint research projects and development of arenas to share experiences, educational and programme developments, and other resources are to be explored and could be offered to the DCs worldwide.

기생충 길들이기

Study of parasite control was a product of transnational interactions among scientists, activists, public, technologies and tools, as well as ecological environments such as parasites in the geopolitical context. This study critically reviews the previous historical analysis on public health programs, which was mainly looked at in a national context. Also, this study emphasizes that the practice of knowledge has been continuously transformed by social, cultural, and ecological factors that occur across the borders, with a specific example of Korea-Japan Joint research project in Jeju from 1970 to 1972 on the control of lymphatic filariasis. Endemic Burgia Malayi filaria provided a unique opportunity for both Korean and Japanese parasitologists to secure a valuable study object as well as model organism. The construction of knowledge about parasite control did not consist solely of research in a laboratory or university. Just as parasitologists continually engaged in the parasite control program and built up the knowledge and skills involved, these activities aimed to be applied to and practiced by the general public. In the process where knowledge constructed in a laboratory meets an external environment, researchers modified the practice according to appropriate social, cultural and ecological factors in local field of study sites.

International transfer of technologies in the conditions of modern challenges

Keywords: international technology transfer, innovation, European Union, implementation
 The globalization of international economic and technological cooperation increases the importance of international technology transfer. It is thanks to him that technology spreads as the most important resource of socio-economicdevelopment. At the international legal level, the international transfer of technologies is regulated by the norms contained in the provisions of universal, regional and bilateral agreements. Ukraine's acquisition of the status of a candidate for EU membership necessitated the implementation of the norms of European law into the legal system of Ukraine.The article examines the main problems of harmonizing the norms of competition law with the norms of legislation on the protection of intellectual property, in particular in the field of technology transfer. Particular attention is paid to the analysis of mergers and acquisitions and other forms of technology transfer, as well as Ukraine's fulfillment of its obligations under the association agreement between Ukraine and the EU, problems and trends in further improvement of the regulatory regulation of technology transfer issues in the field of public procurement and state aid are identified. It is determined that the technical assistance provided to Ukraine by the partner states requires a review not only of national norms regarding technology transfer, but also the creation of new norms of international technical cooperation in the military, technical and medical spheres. It is noted that access to the latest equipment and technologies can be a significant impetus for the development and restoration of the state, however, this requires working out new mechanisms of cooperation with international partners and support from the state and business, in particular in terms of the creation of new industries and joint scientific research, the results of which can become the basis for the restoration of the state and a long-term strategic partnership.

(Invited) Effect of Water Management in Membrane and Cathode Catalyst Layers on Suppressing the Performance Hysteresis Phenomenon in Anion-Exchange Membrane Fuel Cells

Anion exchange membrane fuel cells (AEMFCs) are vulnerable to water management problems, since water is produced at the anode and consumed at the cathode. Previously we found severe voltage losses when increasing the current density in an AEMFC with a commercial Fe–N–Cp cathode catalyst and an in-house-developed anion exchange ionomer (quaternized poly(arylene perfluoroalkylene), i.e., QPAF-4, developed in this laboratory (Figure 1)1,2. In the present work,3 we have clearly identified the problem as being related to water management and developed two approaches to alleviating the problem: i) by use of a thin hydrophilized membrane, the diffusivity of water at the surface was improved, and the severe I–V hysteresis was suppressed, despite the cell using an Fe–N–Cp cathode catalyst with high-water absorption (Figs. 2a and 3a); ii) the voltage loss was also alleviated by the use of a recently developed Fe–N–Cc catalyst with higher hydrophobicity, which decreased the absorption of back-diffusing water into the catalyst layer and increased the amount of water supplied to the reaction sites. These improvements have demonstrated that water transport is the main limitation for the previously reported hysteresis and provide strategies to achieve higher performance AEMFCs through proper water management and formation of water transport pathways (Figs. 2b and 3b). Acknowledgements This project was partly supported by the New Energy and Industrial Technology Development Organization (NEDO) Japan through funds for the “Advanced Research Program for Energy and Environmental Technologies,” by the Japan Society for the Promotion of Science (JSPS) and the the Swiss National Science Foundation (SNSF) under the Joint Research Projects (JRPs) program, and by the Japan Science and Technology (JST) through the Strategic International Collaborative Research Program (SICORP). We are grateful to Pajarito Powder supplying the Fe–N-Cp catalyst. Also, we are deeply grateful to Dr. Weilin Xu and Dr. Ping Song of Changchun Institute of Applied Chemistry and Dr. Shuanjin Wang of Sun Yat-sen University for supplying the Fe–N-Cc catalyst, and to Takahata Precision Co. Ltd. for kindly providing the QPAF-4 membrane and ionomer. References H. Ono, T. Kimura, A. Takano, K. Asazawa, J. Miyake, J. Inukai, K. Miyatake, Robust anion conductive polymers containing perfluoroalkylene and pendant ammonium groups for high performance fuel cells, J. Mater. Chem. A 5 (2017) 24804–24812, https://doi.org/10.1039/c7ta09409d.K. Otsuji, N. Yokota, D. A. Tryk, K. Kakinuma, K. Miyatake, M. Uchida, Performance hysteresis phenomena of anion exchange membrane fuel cells using an Fe–N–C cathode catalyst and an in-house developed polymer electrolyte, J. Power Sources, 487 (2021) 229407, https://doi.org/10.1016/j.jpowsour.2020.229407K. Otsuji, Y. Shirase, T. Asakawa, N. Yokota, K. Nagase, W. Xu, P. Song, S. Wang, D. A. Tryk, K. Kakinuma, J. Inukai, K. Miyatake, M. Uchida, J. Power Sources, 522 (2022) 230997, https://doi.org/10.1016/j.jpowsour.2022.230997 Figure 1

Overseas vietnamese in Russia and their contributions to the promotion of bilateral relations

This article is devoted to the formation, current position, and development prospects of the overseas Vietnamese community in Russia. The purpose of the study was to critically review the directions of work of the authorities in the interests of the Diaspora and in order to strengthen mutually beneficial cooperation between the two countries in the socio-economic, cultural, scientific, technical and political spheres. The authors relied on empirical data, including official statistics on migration from Vietnam to Russia, the main indicators of the socio-economic situation in Vietnam as the major factor of emigration, as well as research publications on the history of the Vietnamese communities formation in Russia. As the result of its analysis, we identified the main areas of cooperation between Vietnam and Russia where the Vietnamese diaspora makes a significant contribution. Accordingly, the paper proposes evidence-based policy recommendations for the government and authorities of Vietnam, which outlined several areas of work with the diaspora in Russia, namely: promoting intercultural dialogue, providing information support and legal assistance for legal migration, developing cooperation in the economy, trade, and labor, as well as joint scientific research and technology transfer.

PTB–INRIM comparison of novel digital impedance bridges with graphene impedance quantum standards

This paper describes an onsite comparison of two different digital impedance bridges when performing measurements on a quantum Hall resistance standard with the purpose of realizing the SI unit of capacitance, the farad. In the EMPIR Joint Research Project 18SIB07 GIQS, graphene impedance quantum standards, the Physikalisch-Technische Bundesanstalt (PTB), Germany, developed a Josephson impedance bridge, and the Istituto Nazionale di Ricerca Metrologica (INRIM) and the Politecnico di Torino (POLITO), Italy, developed an electronic digital impedance bridge. The former is based on Josephson waveform generators and the latter on an electronic waveform synthesizer. The INRIM–POLITO impedance bridge was moved to PTB and the two bridges were compared by measuring both temperature-controlled standards and a graphene AC quantized Hall resistance (QHR) standard. The uncertainties for the calibration of 10 nF capacitance standards at 1233 Hz are within 1 × 10−8 for the PTB’s bridge and around 1 × 10−7 for the INRIM–POLITO’s bridge. The comparison mutually validates the two bridges within the combined uncertainty. The result confirms that digital impedance bridges allow the realization of the SI farad from the QHR with uncertainties comparable with the best calibration capabilities of the BIPM and the major National Metrology Institutes.

Calibration of insulin pumps based on discrete doses at given cycle times.

One application in the medical treatment at very small flow rates is the usage of an Insulin pump that delivers doses of insulin at constant cycle times for a specific basal rate as quasi-continuous insulin delivery, which is an important cornerstone in diabetes management. The calibration of these basal rates are performed by either gravimetric or optical methods, which have been developed within the European Metrology Program for Innovation and Research (EMPIR) Joint Research Project (JRP) 18HLT08 Metrology for drug delivery II (MeDDII). These measurement techniques are described in this paper, and an improved approach of the analytical procedure given in the standard IEC 60601-2-24:2012 for determining the discrete doses and the corresponding basal rates is discussed in detail. These improvements allow detailed follow up of dose cycle time and delivered doses as a function of time to identify some artefacts of the measurement method or malfunctioning of the insulin pump. Moreover, the calibration results of different basal rates and bolus deliveries for the gravimetric and the optical methods are also presented. Some analysis issues that should be addressed to prevent misinterpreting of the calibration results are discussed. One of the main issues is the average over a period of time which is an integer multiple of the cycle time to determine the basal rate with the analytical methods described in this paper.

Challenges on the European Union-China cooperation in higher education from ‘people-to-people dialogue’ perspective: The case of health-related joint projects

The European Union (EU) and People’s Republic of China have a tradition of cooperation in Higher Education (HE) that has been increasingly developed since the Chinese reform of economic opening. From 2012 onwards, when the EU-China High-Level People-to-people Dialogue was established as the third pillar of a Comprehensive Strategic Partnership between both parties, this cooperation in HE was enhanced, particularly in terms of people mobility (students, teachers and researchers). Along with this, globalization and the need for global governance responses in terms of global issues like climate changes, water and food security, pandemics and other health issues lead us to reflect about the role of academic and scientific cooperation - in the domain of HE and research cooperation-in the lens of this People-to-People approach. By means of a literature review grounded on different sources of documents (scientific articles; policy briefs; joint statements and educational programs) and their content analysis, the aim of this paper is to trace a brief state-of-the-art of the EU-China relations in the field of HE and research to analyze if there are effective EU-China partnerships in HE as a whole, and in health scientific joint research projects in particular, by mapping health-related projects involving the EU’s and PRC’s academic and research institutions, as well as their goals.

Generation of CO2 gas mixtures by dynamic dilution for the development of gaseous certified reference materials

The use of Certified Reference Materials (CRMs) is of utmost importance to achieve the comparability and traceability of data, which are essential features of measurement results in environmental and climate fields. The present paper focuses on the generation of gas mixtures at known composition of carbon dioxide at atmospheric amount-of-substance fraction in synthetic air by means of a dynamic dilution system, designed and implemented at the Istituto Nazionale di Ricerca Metrologica (INRiM). The validation of the dynamic system in terms of amount-of-substance fraction is presented. The system was also used to verify the carbon dioxide amount-of-substance fraction of a suite of gas mixtures gravimetrically prepared at INRiM in the framework of the EMPIR Joint Research Project 19ENV05 – STELLAR. Dynamic dilution proved to be an effective tool for the preparation and certification of CRMs for gaseous pollutants (i.e. carbon dioxide, nitrogen oxides) relevant for monitoring environmental pollution and climate changes.

Formation of ICT competencies of future masters of pedagogical education in the aspect of joint scientific research activities in the network community

Formation of ICT competencies of future masters of pedagogical education in the aspect of research activities is one of the important areas of their training. Research activities are quite effective in the conditions of professional interaction and communication in network scientific communities. Seizing the opportunity of independent establishment of professional competencies by an organization, let us to expand the scope of ICT competencies, including the following professional competency: the ability to use ICT tools to organize network interaction between teachers in order to solve urgent research problems. Formation of ICT competencies of future masters in the aspect of joint research activities in the community is more effective when using a social constructivist approach based on the Lev Vygotsky’s sociocultural theory on construction knowledge through social interaction, and the presence of the following didactic conditions: a complex of research tasks; joint cognitive activity in the process of performing research tasks; organization of interaction in the environment of the network community. Joint activity in solving research tasks allows students to better understand the topic under study, increase the motivation for cooperation within the group. Interaction within the network community allows students to better master ICT tools, master its social norms, rules, values, to learn how to solve actual research problems mutually, thereby forming ICT competencies.

지속 가능한 교양으로의 전환

Objectives This article explores a German university case that integrates the principles and values of sustainable development principles into all aspects of the German higher education system. The study sets out to provide practical implications for the development strategies from a sustainable development perspective to support general education in South Korea. Methods This paper gives an overview of the higher education system for implementation while the significance of this study lie in the practice and possibilities of general education. Theses are examined to probe how Germany adapts and applies a whole-institution approach to embed the value of sustainable development. A German university case of adapting the whole-institutional approach towards sustainability is then provided. Priority action areas are reviewed for the analysis of sustainable development in action through the approach to Education for Sustainable Development in the illustrative case. Results The characteristics of the German higher education system that realizes the value of sustainable development are as follows. A concept of sustainable development builds upon the global framework for implementation of sustainable development such as the Global Action Programme on Education for Sustainable Development(ESD): Towards achieving the Sustainable Developing Goals(SDG). A joint research project funded by the Federal Ministry of Education and Research(BMBF) is to establish guidelines for higher education for sustainable development. Based on the guideline each university develops a common concept of sustainability and transformative action program that promote the whole-institution approach. Conclusions Main findings of this research provide insights for general higher education in South Korea. This approach will prove useful in expanding our understanding of how apply to the whole-institution approach to general education in South Korea.

Landslide Fatality Occurrence: A Systematic Review of Research Published between January 2010 and March 2022

Landslides triggered by rainfall kill people worldwide, and frequent extreme events that are expected to be an effect of climate change could exacerbate this problem. This review aims to identify recent research, highlighting both the dynamics of landslide accidents and the characteristics of victims. From SCOPUS and WOS databases, using the PRISMA (preferred reporting items for systematic reviews and meta-analysis) approach, 25 articles written in English, published in the January 2010–March 2022 period and focused on landslide fatalities, were mined. The selected articles recognized a worldwide underestimation of landslide fatalities and analyzed landslide mortality from three perspectives, indicating the importance of this topic for a multidisciplinary research community. The papers focused on (a) fatal landslides and their geographic distribution, seasonality, trends, and relationships with socioeconomic indicators; (b) landslide fatalities and their behaviors and the dynamics of accidents; and (c) clinical causes of death or injury types, aiming to improve emergency rescue procedures. The gaps that emerged include (a) the insufficient reuse of valuable fatality databases; (b) the absence of simple take-home messages for citizens, practitioners, schoolteachers, and policymakers, aiming to set educational campaigns and adaptation measures; and (c) the lack of joint research projects between researchers working on landslides and doctors treating victims to provide complete research results that would be able to actually reduce landslide mortality.

Study protocol: International joint research project 'climate change resilience of Indigenous socioecological systems' (RISE).

BackgroundAnthropogenic changes in the environment are increasingly threatening the sustainability of socioecological systems on a global scale. As stewards of the natural capital of over a quarter of the world’s surface area, Indigenous Peoples (IPs), are at the frontline of these changes. Indigenous socioecological systems (ISES) are particularly exposed and sensitive to exogenous changes because of the intimate bounds of IPs with nature. Traditional food systems (TFS) represent one of the most prominent components of ISES, providing not only diverse and nutritious food but also critical socioeconomic, cultural, and spiritual assets. However, a proper understanding of how future climate change may compromise TFS through alterations of related human-nature interactions is still lacking. Climate change resilience of indigenous socioecological systems (RISE) is a new joint international project that aims to fill this gap in knowledge.Methods and designRISE will use a comparative case study approach coupling on-site socioeconomic, nutritional, and ecological surveys of the target ISES of Sakha (Republic of Sakha, Russian Federation) and Karen (Kanchanaburi, Thailand) people with statistical models projecting future changes in the distribution and composition of traditional food species under contrasting climate change scenarios. The results presented as alternative narratives of future climate change impacts on TFS will be integrated into a risk assessment framework to explore potential vulnerabilities of ISES operating through altered TFS, and possible adaptation options through stakeholder consultation so that lessons learned can be applied in practice.DiscussionBy undertaking a comprehensive analysis of the socioeconomic and nutritional contributions of TFS toward the sustainability of ISES and projecting future changes under alternative climate change scenarios, RISE is strategically designed to deliver novel and robust science that will contribute towards the integration of Indigenous issues within climate change and sustainable agendas while generating a forum for discussion among Indigenous communities and relevant stakeholders. Its goal is to promote positive co-management and regional development through sustainability and climate change adaptation.

Learning Analytics Dashboards for Online Collaboration Whiteboards: Feasibility Check of an Activity Dashboard to Support the Evaluation of Student Activity within Miro

Purpose: Current developments due to ongoing socioeconomic transformations have increasingly boosted the digitalisation process and thus, have shifted the work domain closer to the internet. This includes the education sector, which results in the rising demand for suitable online learning opportunities. In the university context, students are frequently challenged with test performances based on collaborative work in joint research projects. The paradigm shift also affects the tutor turning him into an e-tutor. In the scope of e-tutoring, tracking and assessment of group-specific or individual-based work performance can be guaranteed by a suitable social analytics solution.
 Study design/methodology/approach: In this work, the design and implementation of a learning analytics dashboard tool for Online Collaborative Whiteboards, especially Miro, is presented.
 Findings: The requirements were derived from focus group interviews with key users.
 Originality/value: The tool features real-time tracking and quantitative evaluation of group and individual user actions.

Anodizing—The pore makes the difference

AbstractThe presentation gives an insight into the fascinating world of anodizing as corrosion protection but also goes far beyond. Starting with an introduction to the formation of anodic oxide films and their characteristic features, the authors briefly outline the subject of pore nucleation and growth. The number, size, and shape of the pores essentially determine the properties and play a crucial role in the final application of the anodizing layers. The tailoring of pore design, considering the final application as well as the use of the porous oxide layers for subsequent functional modifications, is demonstrated by examples, exclusively developed in the working groups of the respective authors or in joint research projects, which were in part professionally accompanied and supported by the German Corrosion Society GfKORR e.V.

Corporate Efforts to Research and Develop Therapeutic Agents for Infectious Diseases That Threaten Human

Overcoming serious infectious diseases such as malaria, tuberculosis, and other neglected tropical diseases (NTDs) that threaten human life around the world is an important issue in global health. Most of these diseases are concentrated in developing and low-income countries, and in order to reinforce drug discovery activities, pharmaceutical companies are actively promoting industry-academia-government partnerships and utilizing funds to stimulate global health activities. In this presentation, three examples of our drug discovery activities are introduced. The first is participation in the Booster project led by Drugs for Neglected Diseases initiative (DNDi) aimed at creating therapeutic agents for leishmaniasis and Chagas disease, an effort supported by the Global Health Innovative Technology (GHIT) Fund. As domestic and overseas pharmaceutical companies participate in the project and provide their own compounds, it is possible to obtain structure-activity relationship information in a short period of time and improve compound potency. We collaborated with DNDi to create a lead compound from one hit compound, and contributed to further enhancement of its activity. The remaining two are collaborations with academia for the creation of new therapeutic agents or vaccines: a joint research project with Hokkaido University Research Center for Zoonosis Control for emerging viral diseases, and a collaboration with Nagasaki University in malaria. In each case, our researchers were based at the university, establishing close working collaborations with the university researchers. Novel solutions for serious infectious diseases are expected by the combination of the high-level basic research capabilities of academia and the drug discovery know-how and original compound libraries possessed by pharmaceutical companies.

Interaction Between Educational Institution and Employers’ Organizations in Cultural Sphere: Study Experience

The article presents the results of the study held in the Chelyabinbsk State Institute of Culture in 2021. The study aimed at the evaluation by employers’ organizations of the university graduates’ preparation level, requirements of professional sphere to the competencies of culture workers, and determination of forms and directions of employers’ participation in educational process. The study showed comparatively high evaluation of educational system results (training of a graduate), the developed personal characteristics, universal and professional competencies of a culture worker. The authors have also revealed a dominant orientation at short-term, local (according to scales, intensity and the tasks realized) directions and forms of interaction between the university and regional sphere of culture. The choice of tools for such interactions indicates a lack of long-term aims, strategic character and focus on the solution of the personnel potential reproduction tasks and integration of cultural institutions into educational process, organization of joint scientific-research, artistic and creative, sociocultural projects. Meanwhile, interaction potential of cultural activity and professional education spheres becomes a factor of protecting and development of regional system of culture, sociocultural transformation of the corresponding territories.