Objective To explore the effect of predictable aid support in tracheal intubation with severe acute organophosphorus pesticide poisoning(SAOPP)patients. Methods A total of 109 patients were randomly divided into treatment group(n=55) and control group(n=54). All the patients were treated with the gastric lavage and catharsis, and accepted atropine, pralidoxime chloride and ventilatory support as prescribed.More predictability ambulance measures were applied to the treatment group such as: reinforcement tracheal intubation, endotracheal intubation tube off alarm device and joint of thermostatic wetting with oxygen driving atomization.The therapy efficacy were compared between the two groups. Results There was no statistically significant difference between the two groups of patients before treatment, such as respiration, heart rate and blood oxygen saturation(P>0.05). The observation group was compared with the control group of 72 hours after treatment, and the difference was statistically significant(P<0.01). The mechanical ventilation time, endotracheal intubation time, monitoring time and length of hospital stay of the observation group were(25.63±3.24) hours, (32.17±3.50) hours, (5.65±1.63) days and (8.52±2.13) days respectively, while the control group were (37.82±3.75) hours, (43.64±3.83) hours, (9.78±1.85) days and(13.79±2.17) days.The differences between the two groups were statistically significant(P<0.01). The incidence of UE and complications of the observation group was significantly lower than those in the control group, while the success rate of rescue was significantly higher than that in the control group, and the difference was statistically significant(P<0.05). Conclusions Foresight rescue support plan in endotracheal intubation can increase the success rate, enhance the efficacy, reduce complications and improve prognosis of SAOPP patients. Key words: Organophosphorus pesticide poisoning; Tracheal intubation; Medical support; Prognosis