One of the top focus areas of the country’s development is development of natural resources of the Far East and Eastern Siberia. When developing these territories, builders have to face many severe conditions of construction, i.e. permafrost and high seismic activity. In such circumstances reliability of buildings can be provided in different ways and one of them is seismic isolation ensured by special foundation structures. For areas of permafrost, pile foundations are the main foundation structures which allow ensuring the building safety under conditions of permafrost persistence and these pile foundations under certain conditions can be considered as elements of flexible ties between buildings and soils. In this case a high pile grid will act as an aseismic foundation. The present research provided in the report is dedicated to specific features of structural solutions of high-grid pile foundations in areas of permafrost which act as aseismic structures during seismic activity.