The authors propose a new approach to assessing the consequences of exposure to ionizing radiation on the structures of the eye. The approach is based on the results recently obtained by the authors together with employees of the Joint Institute for Nuclear Research in Dubna, according to which radiation exposure causes oxidation of the bisretinoids contained in the structures of the eye - the retina and retinal pigment epithelium. As a result of this oxidation, the fluorescence spectrum of bisretinoids shifts to the blue region of the visible spectrum. The shift in the fluorescence spectrum can be recorded non-invasively using the method of recording fundus autofluorescence, which is currently generally accepted in ophthalmology. Since the oxidation of bisretinoids occurs during radiation exposure, it becomes possible almost immediately after irradiation to assess the degree of impact of ionizing radiation on both the structures of the eye and the body as a whole. There is no analogue to such a non-invasive assessment of the effects of radiation on the body. The proposed approach may become important for assessing the radiation safety of nuclear industry workers, astronauts, and patients undergoing proton or gamma therapy.
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