Jaundice In Adults Research Articles

Cholestatic jaundice in adults. Algorithms for diagnosis

Cholestatic jaundice in adults. Algorithms for diagnosis

The Liver Function in the Newborn Investigated by Urobilinogen Tolerance Tests

SUMMARYTo elucidate the etiology of icterus neonatorum which is still obscure urobilinogen tolerance tests were performed on 31 newborn and a few infants with diseases of the liver and bile passages. The technic of WITH (1946) was used. The results of the investigation point towards the existence of some degree of liver insufficiency in the newborn, but they are difficult to evaluate as the test is also influenced by other factors than the liver function, presumably the kidney function. The test is consequently of no use as a functional liver test in infants.Attention is drawn to the fact that the serum bilirubin concentration in icterus neonatorum is much higher than in the forms of hemolytic jaundice in adults, which speaks against the hemolytical theory of the origin of icterus neonatorum.

JAUNDICE IN CHILDREN

INTRODUCTION I have not been able to find a comprehensive analysis. of the experience of any one pediatric service with jaundice in children. Although there are several classifications of jaundice, notably those of Rich,1Barron2and Martin,3they are based either on postmortem examinations and experimental work or on a study of a group of adults. Since many conditions which commonly give rise to jaundice in adults are extremely rare in infants and in children, while conditions which are frequent and important in children seldom if ever occur in adults, it seems desirable to have a classification based on pediatric experience. I have attempted to pick the best classification from that point of view. In addition, I have summarized the existing experimental evidence regarding the various types of jaundice, the mechanism of their Production, and the tests which are important in differentiation and I have included an

JAUNDICE IN CHILDREN

INTRODUCTION I have not been able to find a comprehensive analysis. of the experience of any one pediatric service with jaundice in children. Although there are several classifications of jaundice, notably those of Rich,1Barron2and Martin,3they are based either on postmortem examinations and experimental work or on a study of a group of adults. Since many conditions which commonly give rise to jaundice in adults are extremely rare in infants and in children, while conditions which are frequent and important in children seldom if ever occur in adults, it seems desirable to have a classification based on pediatric experience. I have attempted to pick the best classification from that point of view. In addition, I have summarized the existing experimental evidence regarding the various types of jaundice, the mechanism of their Production, and the tests which are important in differentiation and I have included an