Seventeen artists' watercolor pigment samples and two Japanese woodblock prints were exposed to 0.40 ppm ozone in a controlled test chamber for three months. It was found that several artists' pigments when applied on paper will fade in the absence of light if exposed to an atmosphere containing ozone at the concentrations found in photochemical smog. Alizarin-based watercolors containing 1,2 dihydroxyanthraquinone lake pigments were shown to be particularly sensitive to ozone damage, as were the yellow pigments used in the Japanese woodblock prints tested. Indoor-outdoor ozone monitoring in a Pasadena, CA art gallery confirmed that ozone concentrations half as high as those outdoors can be found in art galleries that lack a chemically protected air conditioning system. Care should be taken to protect works of art from damage due to photochemical smog.