The East Japan Railway Company is planning a new access railway line to the Tokyo International (Haneda) Airport. This paper proposes an evaluation method for the development of the new airport access line considering the socioeconomic characteristics of the Greater Tokyo Area and indicates what is needed to increase its social value. As the evaluation method, we develop an econometric model that considers commuters’ trip behaviors across prefectures and the relationship between the increased number of Meeting, Incentive Travel, Convention, Exhibition and Event (MICE) visitors and the regional economy. We also conduct a simulation analysis using an empirical econometric model and a cost-effectiveness analysis based on multiple scenarios. The results indicate that a 50% increase in MICE visitors is needed to make the present discounted value of the total increase in the gross regional product larger than the construction cost of the line.