Yield curves for the production of117gIn,117mIn,116m1In,115mIn,113mIn,111In,110hIn,110lIn,109In,108hIn and108lIn from enriches118Sn have been measured by the activation method in the energy region 75–800 MeV. The cross sections have been deduced and for117In,110In and108In isomeric cross section ratios have been determined. The experimental cross sections are compared to calculations with a cascade-evaporation model and to cross sections calculated with a semi-empirical formula. The isomeric ratios are compared to calculations based on the statistical formalism by Huizenga and Vandenbosch together with cascade-evaporation theory. The (γ, p) cross section and isomeric ratio are also compared to calculations based on a direct knock-out formalism.