The goal in many fault detection and isolation schemes is to increase the isolation and identification speed. This paper, presents a new approach of a nonlinear model based adaptive observer method, for detection, isolation and identification of actuator and sensor faults. Firstly, we will design a new method for the actuator fault problem where, after the fault detection and before the fault isolation, we will try to estimate the output of the instrument. The method is based on the formation of nonlinear observer banks where each bank isolates each actuator fault. Secondly, for the sensor problem we will reformulate the system by introducing a new state variable, so that an augmented system can be constructed to treat sensor faults as actuator faults. A method based on the design of an adaptive observers’ bank will be used for the fault treatment. These approaches use the system model and the outputs of the adaptive observers to generate residues. Residuals are defined in such way to isolate the faulty instrument after detecting the fault occurrence. The advantages of these methods are that we can treat not only single actuator and sensor faults but also multiple faults, more over the isolation time has been decreased. In this study, we consider that only abrupt faults in the system can occur. The validity of the methods will be tested firstly in simulation by using a nonlinear model of waste water treatment process with and without measurement noise and secondly with the same nonlinear model but by using this time real data.