ISI Databases Research Articles

Common Types and Methods of Drug Usage In Iran: A Systematic Review and Meta-Analysis

Introduction: Drug usage is a prevalent social and health problem in most countries. The highest prevalence of drug abuse has been reported among people aged 30-40 years old. The purpose of this study was to determination of the types of drugs and the methods of drug usage in Iran in a systematic and meta-analysis study.Methods: This study was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Databases ofSID, Iran Doc, ISI, Cochrane library, Science direct, PubMed/Medline, and Scopus were independently searched by two researchers using MeSH keywords. Articles published between 2004 and 2018 were recruited.Data was analyzed using random effectsmodel using STATA-SE12 software. Heterogeneity among studies was investigated using, T2 and I2statistical indices.Results: Initial search retrieved 90 articles from which 7 articles with desirable quality were finally analyzed. Opium was the most common in used narcotic50 %(95% CI: 35-66%) followed by opium extract44%(95% CI: 5-83%), and heroin 19%(95% CI: 12-26%). Using more than one narcotic was observed in 9% (95% CI: 4-15%). The inhalation was the most common method of usage72 %( 95% CI: 61-83%) followed by oral consumption 32%(95% CI: 9-54%) and injection 14%( 95% CI: 05-24%).Conclusion: Drug abuseis a common phenomenon in Iran. It is amenable to reduce the tendency to using drugs by providing appropriate training, informing the risks of drug abuse, and identifying and educating high-risk groups.

Time to First Cigarette: A Potential Clinical Screening Tool for Nicotine Dependence

The time to first cigarette (TTFC) of the day has been identified as the best single-item indicator of nicotine dependence. However, TTFC has not been extensively used in clinical settings and is not a criterion for tobacco use disorder, perhaps due to a lack of information about TTFC's predictive value. This review provides a synthesis of the accumulating literature on TTFC's relationships with nicotine dependence, identify gaps, and inform future clinical and epidemiologic research of potential uses of TTFC. A systematic review of the literature was conducted using PubMed, Google Scholar, and Web of Science ISI databases. We identified 16 articles examining the relation between TTFC and negative outcomes associated with high levels of nicotine addiction and Tobacco Use Disorders (eg, high levels of nicotine and toxicant exposure, progressive use over time, failed cessation, head-and-neck cancers). Earlier TTFC was consistently associated with greater likelihood of cessation failure and relapse, and higher levels of biomarkers of tobacco exposure. Several of these associations were found among both adult and adolescent smokers, and remained even after accounting for smoking behaviors (eg, cigarettes/day). Earlier TTFC is a key indicator of greater nicotine dependence. Knowledge of a smoker's TTFC may allow clinicians to accurately inform smokers of health risks and assign greater resources during cessation attempts. Smokers may be able to use TTFC to self-select cessation aids and accurately assess their unique smoking-related health risks. TTFC may be a better item than cigarettes/day for accurately quantifying dependence and risk in epidemiologic studies.

Association between diabetes and vestibular dysfunction: an integrative review

ABSTRACT Purpose: to identify, in the literature, the factors associated with the development of vestibular dysfunctions in individuals with type 2 diabetes mellitus (DM2). Methods: an integrative review of the literature, whose survey was conducted in the databases ISI, SciELO, LILACS and PubMed, using the following descriptors: “type 2 diabetes mellitus”, “vertigo”, “dizziness”, and “vestibular diseases". Articles published in the last 10 years that answered the research question (“What factors are associated with the development of vestibular disorders in individuals with DM2?”) were included in the study. Results: the search returned 426 articles, 10 of which met the eligibility criteria. Most of the participants of the selected studies who had vestibular dysfunctions were women over 40 years old and had more than one comorbidity related to DM2, the main one being the systemic arterial hypertension (SAH). According to the literature, the physiology of the inner ear allows small glucose alterations to influence its normal functioning, which makes diabetic individuals more susceptible to developing vestibular dysfunctions. Conclusion: according to this study, DM2 can trigger or contribute to the manifestation of vestibular dysfunction, whose main associated factors are advanced age, female gender, and various comorbidities, as dyslipidemia, SAH and metabolic syndrome.

The Comparison of Different Irrigation Systems to Remove Calcium Hydroxide from the Root Canal: A Systematic Review and Meta-Analysis

Objective: To examine the effect of a variety of irrigation systems on the removal of root canal Ca (OH)2 residues through meta-analysis and systematic review. Material and Methods: A search of relevant articles was systematically performed on databases of Medline, PubMed, Cochrane Library, Embase, ISI, and Google Scholar published from 2013 to 2019. Electronic title management was carried out by EndNote X9 software. Searches were based on the main keywords of “Irrigation Systems”, “Calcium Hydroxide”,” Root Canal”, “Self-adjusting File OR SAF”, “Conventional Irrigation”, “EndoVac System”, “Ultrasonic Irrigation” and “YAG Laser”. Results: The studies investigated were found to lack any standardization concerning the irrigation method used or the measurement of outcomes; for instance, different studies used 5 or 10 mL of 2.5% NaOCl, or 5 mL of 5.25% NaOCl, or 0.5 mL, 3 mL and 10 mL of 17% EDTA. Conclusion: The effective techniques for the removal of root canal Ca(OH)2 were PUI, and SAF approaches.

The effects of parental depression and anxiety on child behavior from 6 to 12 years old: a review

ABSTRACT Background: Parental depression and anxiety are relevant factors that may influence child externalizing and internalizing behavior; also influenced by stigmatized knowledge about such mental illnesses. Objectives: To identify which instruments were used in studies on the effects of parental depression and anxiety on child behavior from 6 to 12 years old; to analyze the main results in offspring's behaviors on articles published between 2011 to 2019. Methods: we did a literature review searching PubMed, BVS, ISI, and Scopus databases; keywords: “Maternal Depression”, “Maternal Anxiety”, “Paternal Depression”, “Paternal Anxiety”, “Mother's (also Mothers') Depression”, “Mother's (also Mothers') Anxiety”, “Father's (also Fathers') Depression”, “Father's (also Fathers') Anxiety”, “Parental Depression”, “Parental Anxiety” AND “Child Behavior”, in Portuguese and English. Results: We found 1,500 articles, after applying the inclusion criteria, n = 23 were selected and analyzed. 78.3% of studies were performed with mothers, 17.4% with both parents, and 0% with fathers alone. Different instruments were used to assess depression or anxiety in parents, and child behavior. Discussion: studies that included both parents and parental anxiety assessments were scarce; no study in this review evaluated only fathers. Social abilities, personality traits, self-conceptions, and knowledge about anxiety and depression could enhance the quality of studies' results.

Revisión sistemática (2010-2017) de los instrumentos de evaluación y programas de rehabilitación de la cognición social utilizados con personas con esquizofrenia

Research is done regarding evaluation instruments and training programs of social cognition in benefit of the rehabilitation processes of patients with schizophrenia. The PRiSM methodology is used, reviewing the Scopus, ISI and ApaPsycNet journals databases, between 2010 and 2017, considering as inclusion criteria pieces of research where instruments with evaluative purposes and rehabilitation programs of the different sub-domains of social cognition for people with schizophrenia are used. 290 articles are found, and 195 which are thoroughly examined, are selected. A summary of 37 instruments is established, and 10 rehabilitation programs of social cognition are described. It is concluded that it is necessary to explicitly state in the literature the properties, reliability and validity of the tests used, so as to measure what is intended to be measured. Also, it is important to describe the programs used in benefit of the social cognition rehabilitation of the patient with schizophrenia.

The implementation of the nursing process in lower-income countries: An integrative review.

AimsThis review study aimed to investigate the strategies for implementing the nursing process in the clinical practice and the assessment of the implementation rate of this process in clinical settings of lower‐income countries.DesignAn integrative review.MethodThe search was conducted of EMBASE, MEDLINE, CINAHL, Scopus and ISI databases from 1975–July 2018. Following the formation of the research team, two researchers independently selected the eligible studies; finally, 39 articles were approved by the research team for this study.ResultsThe researchers identified three themes: Effects of implementing the NP in clinical settings, Development and application of electronic software in the NP and Factors affecting the implementation of the NP. This review revealed that nurses and nursing managers in hospitals are interested in implementing the nursing process in the form of widely and continuously. But the necessary infrastructure, such as manpower, electronically or manually tools, has not yet been provided, and the implementation of the nursing process is done either imperfectly or not done.

An updated systematic review on the applied TST and IGRA Test for diagnosing LTBI in patients treated with TNF-α inhibitor drugs

Present systematic review was designed to compare the efficacy of interferon-γ release assays (IGRAs) and tuberculin skin test (TST) for diagnosing latent tuberculosis infection (LTBI) in patients subjected to the anti-TNF-α therapy. The MEDLINE (Ovid), PubMed, Embase, Scopus, Cochrane library, and Web of Science ISI databases were searched for selecting studies to compare the efficiency of IGRAs [QuantiFERONTB Gold (QFT-GT), QuantiFERON-TB Gold In-Tube (QFT-GIT)and T-SPOT.TB] and TST in patients under the anti-TNF-α therapy. After evaluating all studies, we systemically reviewed the results of 37 studies with a total sample size of 8584 patients. The agreement between IGRASs and TST was poor to moderate, however, the anti-TNF-α therapy mostly decreased the percentage of this agreement. BCG vaccination could cause false results of TST assay. The developed active TB in patients with IGRAs positive results during follow-up showed lower than TST positive patients. In conclusion, in the treated patients with anti-TNF-α with previous BCG vaccination, IGRAs might be the better assay to diagnosis LTBI by reducing the false results rate in comparison with the TST. However, more investigations should be done to compare the advantage of IGRAs with conventional test in the treated patients with TNF-α antagonists.

The effect of omega-3 and vitamin E on oxidative stress and inflammation: Systematic review and meta-analysis of randomized controlled trials.

Background: Several studies have investigated the effect of omega-3 fatty acids and vitamin E on oxidative stress and inflammation, but their findings are inconsistent. The aim of this meta-analysis is to elucidate the overall effects of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation. Methods: We searched titles, abstracts, and keywords of relevant articles indexed in PubMed, ISI, Scopus, and Google Scholar databases up to December 2018 to identify eligible RCT studies. Random effects model was used to estimate the pooled effect of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation. Results: Overall, 7 RCTs with 504 participants were included in this meta-analysis. We found that co-supplementation with omega-3 fatty acids and vitamin E decreased hs-CRP (weighed mean difference (WMD)=-2.15mg/L; 95% CI: -3.40, -0.91mg/L; P<0.001) concentrations and increased total antioxidant capacity (TAC) (WMD=92.87mmol/L; 95% CI: 31.97, 153.77mmol/L; P=0.03), and nitric oxide levels (NO) (WMD: 6.95μmol/L; 95% CI: 3.86, 10.04, P<0.001) compared with control group. Omega-3 fatty acids and vitamin E had no significant effect on malondialdehyde (MDA) (WMD: 1.54mmol/L; 95% CI: -1.29, 4.36; P=0.196), and glutathione (GSH) (WMD: 20.87mmol/L; 95% CI: -20.04, 61.6, P=0.31) levels. Conclusion: The present meta-analysis found that omega-3 fatty acids and vitamin E co-supplementation significantly decreased hs-CRP and increased NO and TAC, although it had no significant effect on MDA and GSH.

Türk Toplumunda Empatinin ve Empatik Becerinin Artırılmasında Empati Eğitim Programlarının Etkililiği: Meta-Analiz Çalışması

The concept of empathy has become a concept that increasingly emphasized in human relations. However, there are some arguments in the literature about whether or not empathic skills can be learned. Based on these discussions, a meta-analysis study was conducted to examine the findings of the studies in which empathic skills training was carried out in the Turkish society. The use of empathy trainings prepared in the focus of empathic skill development, its application to the Turkish society and its implementation within the last 20 years have been determined as the inclusion criteria of the study. In line with these criteria, it is planned to reach the articles published in national and international refereed journals with the master's and doctoral theses carried out empathy training. Google Scholar, Scopus, ISI Database, Turkish Council of Higher Education National Thesis Center, To-kat, and Ulakbim database are scanned with Empathy, Empathy Training, Empathy Skills words. As a result of this screening, 13 studies were reached in accordance with the search criteria. For the analysis of the data, Hedges' formula g was used to calculate the effect size by means of the Comprehensive Meta Analysis (CMA) program. The mean effect size of 13 studies included in the study was found to be E = + 5,668. The high effect size of our study shows that empathy education programs are effective in increasing empathy and empathy skills in Turkish society.

The efficacy of standard versus accelerated epi-off corneal cross-linking protocols: a systematic review and sub-group analysis

To compare the one-year efficacy of accelerated and standard 5.4J/cm2 protocols of cross-linking (CXL) in the treatment of progressive keratoconus. In this systematic review, two members of the research team searched Scopus, Pubmed, ISI, Ovid, Science Direct, and Cochrane databases independently for publications between January 2010 and December 2016. The majority of retrieved studies were not randomized clinical trials (RCT), or the second arm of the RCT was either untreated or customized CXL. The outcomes of interest were uncorrected distance visual acuity, corrected visual acuity, manifest refraction spherical equivalent, maximum keratometry in the central 3mm, minimum keratometry in the central 3mm, and corneal thickness in the apex or thinnest point at baseline and 1year after CXL. Of the 453 papers found in the preliminary search, 23 papers were included in the final analysis. Analysis of variance of one-year changes showed that longer irradiation times were associated with a greater corneal flattening effect, although there was no difference in terms of improvement in vision or refraction. In other words, efficacy is comparable among different CXL protocols, so it is recommended to use the standard method in cases where maximum flattening is expected, such as young people and severe cases.

Conceptual Model of Medication Adherence in Older Adults with High Blood Pressure-An Integrative Review of the Literature.

Background: Medication adherence (MA) is the most important controlling factor of high blood pressure (HBP). There are a few MA models, but they have not been successful in predicting MA completely. Thus, this study aimed to ex-pand a conceptual model of MA based on an ecological approach. Methods: An integrative review of the literature based on theoretical and empirical studies was completed. Data source com-prised: Medline (including PubMed and Ovid), ISI, Embase, Google scholar, and internal databases such as Magiran, Google, SID, and internal magazines. Primary English and Persian language studies were collected from 1940 to 2018. The steps of study included: (a) problem identification, (b) literature review and extracting studies, (c) appraising study quality, (d) gathering data, (e) data analysis using the directed content analysis, (f) concluding. Results: Thirty-six articles were finally included and analyzed. After analysis, predictors of MA in older adults with hyper-tension were categorized into personal, interpersonal, organizational, and social factors. Although the personal factors have the most predictors in sub-categories of behavioral, biological, psychological, knowledge, disease, and medication agents, social, organizational and interpersonal factors can have indirect and important effects on elderly MA. Conclusion: There are many factors influencing MA of elderly with HBP. The personal factor has the most predictors. The designed model of MA because of covering all predictor factors, can be considered as a comprehensive MA model. It is sug-gested that future studies should select factors for study from all levels of the model.

The role of AI classifiers in skin cancer images.

The use of different imaging modalities to assist in skin cancer diagnosis is a common practice in clinical scenarios. Different features representative of the lesion under evaluation can be retrieved from image analysis and processing. However, the integration and understanding of these additional parameters can be a challenging task for physicians, so artificial intelligence (AI) methods can be implemented to assist in this process. This bibliographic research was performed with the goal of assessing the current applications of AI algorithms as an assistive tool in skin cancer diagnosis, based on information retrieved from different imaging modalities. The bibliography databases ISI Web of Science, PubMed and Scopus were used for the literature search, with the combination of keywords: skin cancer, skin neoplasm, imaging and classification methods. The search resulted in 526 publications, which underwent a screening process, considering the established eligibility criteria. After screening, only 65 were qualified for revision. Different imaging modalities have already been coupled with AI methods, particularly dermoscopy for melanoma recognition. Learners based on support vector machines seem to be the preferred option. Future work should focus on image analysis, processing stages and image fusion assuring the best possible classification outcome.

Effects of prenatal and postnatal exposure to organophosphate pesticides on child neurodevelopment in different age groups: a systematic review.

Exposure to pesticides is a major factor in the cause of dysfunction in the nervous system and neurodevelopment disorders in children at critical periods of great vulnerability. The aim of this study was to review scientific evidence published on neurodevelopmental effects of prenatal and postnatal exposure to organophosphate pesticides (OPs) in different stages, including neonates, infants, toddlers, preschool children, and school-age children. Full-text articles published in PubMed, Scopus, and ISI databases between 1973 and 2019 were reviewed and the scientific evidence was evaluated. Results: Fifty studies were eligible for inclusion in this quantitative synthesis. Fifteen of these papers evaluated the effects on neonates and infants, 18 on the effects on toddlers and preschool children, and 24 the effects on school-age children. Considerable evidence suggests that prenatal exposure to OPs contributes to child neurodevelopment disorders in all stages, whereas data about the effects of postnatal exposure are limited. Therefore, the available evidence supports the theory that sensitive time-windows occur prenatally rather than postnatally. Although 45 out of the total 50 selected articles found an association between OP exposure and child neurodevelopment, some of the evidence is controversial. A standardized methodology is needed to enable the comparison of the results in several studies, and further research studies are needed to warrant firmer conclusions. A systematic review of this evidence should be performed continuously to update the state of knowledge regarding neurodevelopmental effects associated with OP exposure.

Demography of Medical Journals in Iran; a Cross-Sectional Study.

Introduction:Policymaking in order to increase the quality of medical journals needs having accurate data from their current status.Objective:The present study was designed with the aim of introducing a demographic scheme of Iranian journals in the field of medical sciences. Method:This cross-sectional study was performed on all the medical journals being published in Iran in 2016. The list of all journal titles was extracted by referring to the medical journals databanks (ministry of health, Magiran, IranMedex, Irandoc and…), and the data required for the study were gathered using journals’ homepages or by phone or in person, by attending the journal’s office.Results:Totally, 521 journals were assessed. Publication language used was English in 297 (57%) journals and 515 (98.85%) were open access. 381 (73.1%) journals were published quarterly and the year of starting publication was 2010 onwards in case of 245 (48.0%) of journals. There were 29 (5.56%) journals, which were indexed in all 3 databases of ISI, PubMed and Scopus. Only 4.81% of the journals had an official impact factor announced by Thomson-Reuters or Clarivate Analytics Company. Mean time needed for review of articles was 1.89 ± 1.52 (0.5 – 12) months (n = 146) and mean time interval between accepting an article and its print or electronic publication was 3.63 ± 2.17 (0 – 12) months (n = 144). Rate of membership of these journals in COPE and ICMJE were 40% and 27%, respectively.Conclusion:Most medical journals being published in Iran were English quarterly journals that were regularly published in the fields of general medicine, open access, with university affiliations, centered in the capital, and more than 80% of them had started publishing from 2000 and afterwards.

Association between Intake and Serum Selenium Levels and Risk Factors of Cardiovascular Disease (Narrative Review)

Background: Selenium (Se) is a necessary elementand is a potent antioxidant adjusting the activity of some enzymes such as glutathione peroxidase (GPx). Selenium metabolism is associated with the biology of heart and its functions, and deficiency is related to pathology. Several studies indicate a relationship between and disease.Objectives: The aim of this study was the investigation of the role of in disease.Methods: We searched the ISI, PubMed, Scopus, and Google Scholar databases for studies that evaluated the association between and health and disease. At first, the studies containing the words , cardiovascular disease, supplementation, levels of selenium and hypertension were selected.We searched papers using ‘selenium_, ‘selenium supplementation_, ‘selenium deficiency_and, ‘Se_in combination with ‘cardiovascular disease_, ‘hypertension_’, ‘heart disease_’, ‘heart failure_’ as keywords. Results: 17 articles (6 randomized clinical trials and 11 observational studies) were eligible to be included in the current review. Some clinical trials showed that supplementation could decrease the risk factors of disease include lipid profiles and inflammatory markers. Observational studies showed that low concentrations are a risk factor of disease however, this is not definitive. But the presence of normal of in the body for antioxidant defense is essential.Conclusion: More clinical trial studies with larger sample size are needed to confirm that is effective in preventing and treatment of disease.

Knowledge creation and knowledge transfer: an perspective under the kibs vision for evaluating the innovative capacity

Introduction: The knowledge creation and knowledge transfer constitute the field of interdisciplinary nature whose scientific configuration has been consolidating in the international scope from its relation with the Knowledge Intensive Business Services – KIBS. Objective: Explain how the elements of a conceptual model based on KIBS (Knowledge Intensive Business Services) can be applied in an integrated way to assess the innovative capacity of firms in the service sector. Methodology: The building of the model is based on a bibliometric analysis of the central theme KIBS, in the databases Scopus and ISI Web of Knowledge (Web of Science). Results: In this study, it can be seen that during the seventeen years of research, the authors did not investigate the relationship between KIBS and the evaluation of the innovative capacity of firms in the service sector. Conclusion: The greater concentration of the analyzed papers investigates the attributes and roles of KIBS for innovation. It's an opportunity to assess the innovative capacity of KIBS in the service sector.

Frequency and Clinical Manifestations of Pediatric Brucellosis in Iran: A Systematic Review

Background Brucellosis is a zoonotic disease that is widely distributed throughout the developing countries. Children are considered as at risk groups for infection. The aim of this study was to assess the frequency and clinical manifestations of Brucellosis in Iranian children and adolescents. Materials and Methods: We systematically searched international databases; ISI, Medline (via PubMed), Scopus, and national databases Irandoc, Barakat knowledge network system, Magiran, and Scientific Information Database (SID). The search strategy was developed based on main terms of Brucellosis, Brucella fever, Gibraltar, Rock Fever, Undulant Fever, Cyprus Fever, Malta Fever, and Bang Disease. Results: A total of 885 studies were identified, from them a total of 12 studies that were conducted between 2001 and 2016 were included. Following the relevancy assessments and quality control, data from the 1,429 participants were presented in our review. The age of the patients ranged from 2 to 18 years. Only one out of twelve studies provided the prevalence of 4.30% and 3.4 incidence. Studies varied greatly in reporting high risk behavior of animal contact (8.4 to76.0%) and unpasteurized dairy (22.4 to 91.6%). Conclusion Our finding reveals the disparity of reported prevalence and clinical manifestations of Brucellosis in Iranian children. Fever and joint pain were the most frequent reported signs. Differences in study design, measurement tools and methods, and sub population sampling, does not provide the possibility of aggregation of data for more comprehensive inference.

An Assessment of Effective Factors in Technology Acceptance Model: A Meta- Analysis Study

Purpose: The main object of this study is to identify the main factors which cause the acceptance or rejection of technology by the users. Methodology: In the present study; the results of studies conducted in the mentioned field were analyzed using statistical methods. The method applied in the current study was meta-analysis. In this study, all studies done in the mentioned field have been searched from three citation databases of ISI, Scopus and ISC, based on the presence of keywords TAM and Technology Acceptance Model in titles, abstracts, keywords, texts and references. For meta-analysis of the studies, means and standard error of variables in the studies were collected and their significance level was measured with the use of means differences. Then, based on tests applied in the studies, the effects size of the variables was calculated based on Hedges approach. Also, Cohen approach was used for their interpretation. Findings: Totally, 164 researches had the property of measuring the effect size. Given the obtained results, twenty-one-dimensional variables with different values are effective in the technology acceptance in environments and based on the type of samples in the studies. Given that all main variables in Davies model had high means and high effect size, it can be concluded that components of Davis’ Technology Acceptance Model (TAM) are still considered as the ideal components in this field. Originality/value: the article have a new methodology to technology acceptance or rejection causes.

A Systematic Review and Meta-analysis on the Prevalence of HBsAg in Health Care Workers from Eastern Mediterranean and Middle Eastern Countries.

Background:The present study aimed to determine the prevalence of HBsAg in Health Care Workers (HCWs) in Eastern Mediterranean Region Office (EMRO) and Middle Eastern countries from 2000 to 2016.Methods:In a meta-analysis study, the databases of PubMed, ISI, Ovid, Scopus, Google Scholar, and Persian databases were searched for relevant articles on the prevalence of HBsAg in HCWs in EMRO and Middle Eastern countries. Homogeneity was assessed based on Cochran's Q-test results.Results:A total of 43 articles (110,179 people) were included. The pooled prevalence of HBsAg in HCWs of EMRO and Middle East countries was found 2.77% (95%CI: 2.64-2.83). The specific prevalence of HBsAg was 2.84% (95% CI: 2.6-3.11) in EMRO and 2.22% (95%CI: 2.13-2.31) in Middle Eastern countries. The highest and lowest prevalence rates of HBsAg among HCWs for countries with more than one study were 6.85% (95% CI: 5.74%–8.16%) in Sudan and 1.00% (95% CI: 0.94%–1.07%) in Turkey, respectively. The trends of HBsAg prevalence among HCWs decreased from 2000 to 2016.Conclusions:Based on the World Health Organization classification of HBV prevalence, intermediate HBsAg prevalence rates were detected in HCWs of EMRO and Middle East countries during 2000–2016.