Plasma behavior and power generation characteristics in a disk-shaped magnetohydrodynamic (MHD) power generator with xenon (Xe)-seeded neon (Ne) working gas have been examined by <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$r$</tex-math> </inline-formula> - <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\theta $</tex-math> </inline-formula> 2-D numerical simulation under the assumptions of isentropic gas flow and a non-MHD interaction. The seed fraction (mole% of Xe in the mixture) is varied from 0.0% (pure Ne) to 100.0% (pure Xe) to assess the effect that Xe seeding has on plasma behavior and power generation characteristics. Adding a small amount of Xe to Ne improves the power performance due to the resulting enhancement of electrical conductivity, whereas adding an excessive amount (over 5.0%) deteriorates the performance. At an appropriate load resistance, uniform plasma structure occurs for low seed fractions. However, the plasma structure becomes nonuniform for excessively high seed fractions (over 5.0%). This result suggests that adding an excessive amount of Xe can reduce the uniformity of the plasma structure in the generator. On the other hand, at low load resistance ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$<$</tex-math> </inline-formula> the appropriate load resistance) and high load resistance ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$>$</tex-math> </inline-formula> the appropriate load resistance), a nonuniform plasma structure occurs for any seed fraction and results in the deterioration of generator performance. The electron temperature ranges for maintaining uniform plasma structure become narrower as the seed fraction increases which can be attributed to the low ionization potential of Xe and its large atomic weight.