The search for new groundwater resource is essential to sustained economic development in arid environment. The purpose of this study was to investigate new water sources using remote sensing and GIS methods. The thematic layers considered in this study are Lithology, Geomorphology, Drainage, Soil, Lineament, Land use and surface water body, which were prepared using the IRS-P6 LISS-III satellite imagery and conventional data. In addition, soil and drainage maps were digitized from published maps. The thematic layers were finally integrated using ArcGIS V 9.2 software to yield a groundwater potential zone map of the study area. Thus, three different groundwater potential zones were identified, namely \'good\', \'moderate\' and \'poor\'. This GIS based output result was validated using water level depth data collected from Institute of Water studies, PWD. Finally, it is concluded that the RS and GIS techniques are very efficient and useful for the identification of groundwater potential zones. Keywords: Groundwater, GIS, Remote Sensing, Thurinjapuram.