Duration Of Irradiation Research Articles

Evolution of surface recombination property of silicon wafers during laser irradiation by differential photocarrier radiometry

Understanding the surface recombination property of semiconductor materials is beneficial for improving the performance of optoelectronic devices. In this paper, differential photocarrier radiometry (PCR) is carried out to investigate the evolution of the surface recombination velocities of silicon wafers induced by laser irradiation. The PCR signal and the surface recombination velocities were found to be strongly dependent on the quality of the wafer surface and the duration of laser irradiation. The native oxide surface was more susceptible to laser irradiation than the Al2O3 passivated surface due to more surface defects being annealed. A surface-defect annealing model was used to explain the transient behavior of the PCR signal and the surface recombination velocity.

Research on Laser-Induced Damage Post-Restoration Morphology of Fused Silica and Optimization of Patterned CO2 Laser Repair Strategy.

Fused silica has become the preferred optical material in the field of inertial confinement fusion (ICF) due to its excellent performance; however, these costly optical elements are vulnerable, and their manufacture is time-consuming. Therefore, the restoration of laser-induced damage for these optical elements is of great value. To restrain the post-restoration raised rim problem in the CO2 laser repair process to improve the restoration quality, the separate influences of key parameters of laser power, irradiation duration, and laser beam diameter on post-restoration pit morphology are compared in combined simulation and experimental studies. An optimized, patterned CO2 laser strategy is proposed and verified; the results indicate that, with the strategy, the rim height decreases from 2.6 μm to 1.52 μm, and maximal photo thermal absorption is decreased from 784.2 PPM to 209.43 PPM.

Facile synthesis of polystyrene‐coated carbon nanotubes via microwave‐assisted in‐situ polymerization and tuning of the DC electrical conductivity and impedance characteristics

AbstractAn attempt has been made to tune the DC electrical conductivity and impedance characteristics of the nanocomposites by coating carbon nanotubes (CNTs). A microwave‐assisted in‐situ polymerization approach is utilized to coat the CNTs with polystyrene and no initiators are used. The nanocomposites are characterized by FE‐SEM, TEM, FT‐IR, Raman and TGA. Based on the morphological studies, a polystyrene layer is detected on the CNTs. According to the TGA results, the weight loss in the temperature range of polystyrene decomposition increases with increasing microwave irradiation time, suggesting a higher polystyrene content. Moreover, the DC electrical conductivity of the nanocomposites, as well as the real and imaginary impedance and dielectric permittivity are explored. It is shown that increasing the irradiation time decreases the DC electrical conductivity and dielectric permittivity but increases the real and imaginary impedance. Since the thickness of the polystyrene layer depends on the duration of microwave irradiation, our method can be used to tune the electrical conductivity and impedance characteristics. This can be applied to practical situations where a particular resistance is required.

PENGARUH DAYA LAMPU ULTRAVIOLET LIGHT EMITTING DIODE (LED) GROWTH TERHADAP PERTUMBUHAN FISIKA TANAMAN SELADA SISTEM HIDROPONIK

Lettuce is a horticultural crop that has many enthusiasts and is widely cultivated using hydroponic systems. One important factor for plant growth is the need for sufficient light to support the process of photosynthesis. Efforts to overcome the lack of light is to use artificial light that comes from LED lights. This study aims to determine the effect of ultraviolet LED growth lamp power on the growth of lettuce plants. This study was divided into two groups: the control group without irradiating LED growth lamps and the experimental group using irradiation of LED growth lamps with a duration of irradiation of 4 hours at night. Parameters observed included plant height, leaf length, leaf width, number of leaves and leaf color in the third week. Analysis of research data used a non-parametric statistical test, namely the Kruskal Wallis test with the help of SPSS 23. The results showed that the power treatment of LED growth lamps had a significant effect on plant height, leaf length, leaf width and number of leaves. However, the power treatment of LED growth lamps did not significantly affect leaf color. The results showed that the best treatment was obtained at 18 watts of power.

The Effect Of Different Curing Time on Giomer’s Fluoride Release

Dental caries is one of the chronic disease of the oral cavity with a prevalence of 45,3% in indonesia. Fluoride is one of the substance that could help in preventing carries and secondary carries. Fluoride can also be found in restorative materials used in dentistry that could release fluoride ions inside the oral cavity. The aim of this study is to determine the differences of different curing time on giomer’s fluoride release.The method used in this study is experimental laboratory design using 27 giomer samples that are divided into 3 groups based on the duration of irradiation of 20 seconds, 40 seconds, and 60 seconds. Fluoride-release were observed by immersing the polymerized restorative material into artificial saliva and then tested using UV-Vis Spectrophotometer with a wavelength of 570 nm. One way ANOVA test showed differences in fluoride levels in the 3 treatment groups with p 0.05. There was a significant difference in fluoride levels between polymerized giomer restorative materials with curing time of 20, 40, and 60 seconds.

PHOTODYNAMIC THERAPY IN THE MANAGEMENT OF ORAL POTENTIALLY MALIGNANT DISORDERS AND ORAL CANCER - AN OVERVIEW

Objective To summarize the effects and safety of photodynamic therapy (PDT) on oral potentially malignant disorder (OPMD) and oral squamous cell carcinoma (OSCC). Study Design An overview was conducted, based on the PRISMA 2020 statement. Electronic searches with no publication date restrictions were made in five databases. Results Twenty-eight studies were included. Of them, 22 articles investigated only OPMDs - with oral lichen planus (OLP) and actinic cheilitis being the most frequent. Three articles focused on OSCC, while the other three covered OPMDs and OSCC. Methodologies used in the studies were heterogeneous. In this sense, 14 different types of photosensitizers were described. Moreover, PDT parameters showed that laser wavelength, power density, and irradiation duration was 320-670 nm, 10-12000 mW/cm2, and 0.5-150 minutes, respectively. Concerning lesion response, 85.9% OSCC presented complete response, while 14.1% showed no resolution. Regarding OPMDs, erythroplakia/leukoerythroplakia showed the best response. Noentheless, OLP showed partial or no response in almost 75% of the cases. Conclusion PDT depends on lesion types and parameters. The disparities in the results could be attributed to the different methodologies. Although evidence demonstrated in the present overview suggested that PDT shows effective responses in OPMDs and OSCC, these findings need to be interpreted carefully. To summarize the effects and safety of photodynamic therapy (PDT) on oral potentially malignant disorder (OPMD) and oral squamous cell carcinoma (OSCC). An overview was conducted, based on the PRISMA 2020 statement. Electronic searches with no publication date restrictions were made in five databases. Twenty-eight studies were included. Of them, 22 articles investigated only OPMDs - with oral lichen planus (OLP) and actinic cheilitis being the most frequent. Three articles focused on OSCC, while the other three covered OPMDs and OSCC. Methodologies used in the studies were heterogeneous. In this sense, 14 different types of photosensitizers were described. Moreover, PDT parameters showed that laser wavelength, power density, and irradiation duration was 320-670 nm, 10-12000 mW/cm2, and 0.5-150 minutes, respectively. Concerning lesion response, 85.9% OSCC presented complete response, while 14.1% showed no resolution. Regarding OPMDs, erythroplakia/leukoerythroplakia showed the best response. Noentheless, OLP showed partial or no response in almost 75% of the cases. PDT depends on lesion types and parameters. The disparities in the results could be attributed to the different methodologies. Although evidence demonstrated in the present overview suggested that PDT shows effective responses in OPMDs and OSCC, these findings need to be interpreted carefully.

Understanding the thermal effect of power ultrasound in cement paste

The thermal effect of power ultrasound (PUS) converts acoustic energy into heat energy and promotes cement hydration, whereas the effective propagation distance and mechanisms are poorly understood. This study employed two distinct water-to-cement (w/c) ratios, specifically w/c = 0.30 and 0.50, in conjunction with four ultrasound power levels (0 W, 100 W, 450 W and 900 W) and four varying durations of ultrasound irradiation (0 min, 3 min, 10 min and 30 min), as independent variables. The temperature–time (T-t) curves of cement paste under different treatment conditions were recorded and analyzed. The improved heat evolution model was used to analyze cement hydration evolution at the sonication stage. The results indicated that the effective ultrasonic distance corresponding to significant temperature elevation was below 100 mm. Additionally, the hydration degree of cement paste showed a conspicuous gradient characteristic when subjected to ultrasonic irradiation. Applying 900 W ultrasound irradiation for 10 min resulted in a more homogeneous temperature field compared to the other experimental groups. This work provides the potential of employing the thermal effect for prestressed cement panels.

Nanocomposites based on porous silicon and reduced graphene oxide for ionizing radiation sensing

In this study, the field-effect transistor (FET) based on the oxidized porous silicon (PS) – reduced graphene oxide (rGO) sandwich-like composite has been created. The electrical characteristics of the obtained FET were studied in both DC and AC modes. I-V curves and switching characteristics of the PS–rGO-based FET were analyzed. An increase in resistance and a decrease in capacitance of the experimental structures have been found in the 25 Hz − 1 MHz frequency range due to the joint action of α-, β-, and γ-radiation. The parameters of the equivalent circuit model of the PS–rGO-based FET before and after irradiation with 226Ra isotope have been determined using the impedance spectra. The formation of radiation-induced defects and the charge accumulation in the PS layer is considered a possible mechanism of the ionizing radiation influence on the graphene FET conductivity. The FET based on the PS–rGO structures has a high potential for application in ionizing radiation sensors due to the linear dependencies of resistance and capacitance on the irradiation duration.

Targeted single-cell gene induction by optimizing the dually regulated CRE/loxP system by a newly defined heat-shock promoter and the steroid hormone in Arabidopsis thaliana.

Multicellular organisms rely on intercellular communication systems to organize their cellular functions. In studies focusing on intercellular communication, the key experimental techniques include the generation of chimeric tissue using transgenic DNA recombination systems represented by the CRE/loxP system. If an experimental system enables the induction of chimeras at highly targeted cell(s), it will facilitate the reproducibility and precision of experiments. However, multiple technical limitations have made this challenging. The stochastic nature of DNA recombination events, especially, hampers reproducible generation of intended chimeric patterns. Infrared laser-evoked gene operator (IR-LEGO), a microscopic system that irradiates targeted cells using an IR laser, can induce heat shock-mediated expression of transgenes, for example, CRE recombinase gene, in the cells. In this study, we developed a method that induces CRE/loxP recombination in the target cell(s) of plant roots and leaves in a highly specific manner. We combined IR-LEGO, an improved heat-shock-specific promoter, and dexamethasone-dependent regulation of CRE. The optimal IR-laser power and irradiation duration were estimated via exhaustive irradiation trials and subsequent statistical modeling. Under optimized conditions, CRE/loxP recombination was efficiently induced without cellular damage. We also found that the induction efficiency varied among tissue types and cellular sizes. The developed method offers an experimental system to generate a precisely designed chimeric tissue, and thus, will be useful for analyzing intercellular communication at high resolution in roots and leaves.

Antibacterial and antibiofilm performance of low-frequency ultrasound against Escherichia coli O157:H7 and its application in fresh produce

Ultrasound technology has been focused on due to its unique advantages in biofilm removal compared with traditional antibacterial methods. Herein, the anti-biofilm properties of low-frequency ultrasound (LFUS) were studied against Enterohemorrhagic Escherichia coli O157: H7 (E. coli O157:H7). After ultrasonication (20 kHz, 300 W) for 5 min, the removal rate of biofilm from polystyrene sheets reached up to 99.999 %. However, the bacterial cells could not be inactivated completely even extending the duration of ultrasonic irradiation to 30 min. Fortunately, this study indicated that LFUS could efficiently weaken the metabolic capacity and biofilm-forming ability of bacterial cells separated from biofilm. It could be associated with the removal of cell surface appendages and damage to cell membrane induced by mechanical vibration and acoustic cavitation. Besides, the genetic analysis proved that the transcription level of genes involved in curli formation was significantly down-regulated during ultrasonic irradiation, thus impeding the process of irreversible adhesion and cells aggregation. Finally, the actual application effect of LFUS was also evaluated in different fresh produces model. The results of this study would provide a theoretical basis for the further application of ultrasound in the food preservation.

Overirradiance conditions and their impact on the spectral distribution at low- and mid-latitude sites

Lately, the photovoltaics community has shown an increased interest in overirradiance conditions as there is the possibility that such conditions might lead to malfunctions in photovoltaic systems. Varying irradiance levels, recurrence, and duration of such conditions have been reported worldwide, but experimental studies on the spectral distribution of overirradiance conditions are still scarce. This work analyses measured spectral irradiance of overirradiance conditions along with spectra under clear and cloudy sky conditions in three different sites at low- (Lima-Peru) and mid-latitudes (Madrid-Spain and Berlin-Germany) collected for two years. The Average Photon Energy (APE) was used as a representative index of the spectral distribution. For each site, taking the APE under clear sky into account as a reference, it could be shown that the spectra under cloudy skies are blue-shifted, and the overirradiance spectra are red-shifted independently of the location. The red-shift is proportional to the irradiance enhancement intensity. In addition, all sites have different degrees of blue–shift for cloudy skies, with Lima, Madrid, and Berlin exhibiting a difference in APE compared to clear sky conditions of 17 meV, 38 meV, and 43 meV on average, respectively. This difference in APE for the overirradiance conditions compared to clear sky conditions is also independent of the location with a mean value of (8 ± 1)meV. These spectral shift observations experimentally confirm prior assumptions that overirradiance conditions predominantly cause an enhancement of the direct spectral irradiance.

Optically activated MEK1/2 inhibitors (Opti-MEKi) as potential antimelanoma agents.

Mitogen-activated protein kinase kinases 1/2 (MEK1/2) play critical roles in the canonical RAS/RAF/MEK/ERK pathway. Highly selective and potent non-ATP-competitive allosteric MEK1/2 inhibitors have been developed, and three of them were clinically approved for the treatment of BRAFV600 -mutant melanoma. However, the accompanying side effects of the systemically administered MEK1/2 drugs largely constrain their tolerable doses and efficacy. In this study, a series of mirdametinib-based optically activatable MEK1/2 inhibitors (opti-MEKi) were designed and synthesized. A structural-based design led to the discovery of photocaged compounds with dramatically diminished efficacy in vitro, whose activities can be spatiotemporally induced by short durations of irradiation of ultraviolet (365nm) light. We demonstrated the robust photoactivation of MEK1/2 inhibition and antimelanoma activity in cultured human cells, as well as in a xenograft zebrafish model. Taken together, the modular approach presented herein provides a method for the optical control of MEK1/2 inhibitor activity, and these data support the further development of optically activatable agents for light-mediated antimelanoma phototherapy.

Influences of Microwave Irradiation on the Physicomechanical Properties and Cerchar Abrasivity Index of Rocks

The research is aimed at exploring the influences of microwave irradiation on the physicomechanical properties and Cerchar abrasivity index (CAI) of rocks. For this purpose, basalt collected in Chifeng (the Inner Mongolia Autonomous Region, China) was taken as research objects to carry out microwave irradiation tests for different durations in a multimode cavity. By using the MTS815 mechanical testing machine and the abrasion servo tester of rocks, mechanical tests and Cerchar abrasion tests were conducted before and after microwave irradiation. Changes in the mass, volume, surface fractures, surface temperature, ultrasonic wave velocity, uniaxial compressive strength (UCS), and CAI of the basalt samples before and after microwave irradiation were analyzed. Results show that the surface temperature of basalt samples linearly increases with the duration of microwave irradiation. The volume and fracture coalescence of the rock samples both increase with the prolonging duration of microwave irradiation. The mass, ultrasonic wave velocity, UCS, and CAI of the basalt samples all decrease with the increase in the duration of microwave irradiation. The reduction of the physicomechanical properties and CAI of rocks indicates that microwave irradiation can reduce the wear of rock-breaking tool and thus improve the efficiency of rock breaking.

Photoresponsive liposomes and LipoParticles by incorporating a photosensitizer agent in their lipid membrane

Liposomes, as self-assembled lipid layer vesicles, have emerged as a promising platform for various biomedical applications such as photodynamic therapy (PDT). LipoParticles are core–shell lipid assemblies with a solid polymer core coated by a lipid membrane, which gather the advantages of both their counterparts. Photosensitizers (PS), used in PDT, are photosensitive molecules than can be activated by an exposure to a light source, leading to the death of pathogenic surrounding cells. In this context, the aim of this study is to elaborate liposomes and LipoParticles incorporating a PS, and to examine their resulting photoresponsive properties by following the release, triggered by an UV irradiation, of incorporated fluorescent (macro)molecules. Al(III) phthalocyanine chloride disulfonic acid (AlPcS2) was chosen as PS, and the release of 5(6)-carboxyfluorescein (CF) or bovine serum albumin conjugated with fluorescein isothiocyanate (BSA-FITC) from liposomes and poly (lactic-co-glycolic acid) (PLGA) core of LipoParticles respectively, was investigated by fluorescence spectroscopy. The results have shown that UV irradiation led to the release of CF molecules depending on the membrane lipid formulation, and that repeated irradiations could increase the amount of CF molecules released from liposomes. The main parameters governing the release of BSA-FITC macromolecules from LipoParticles were the temperature of their elaboration (corresponding to a reorganization of several liposomes on the surface of PLGA particles), the initial PS concentration, and the duration of UV irradiation. Best results were found with a temperature of the LipoParticles elaboration of 20 °C, a PS concentration of 0.1 mM, and a duration of irradiation of 5 min. These results support the fact that similarly to liposomes, LipoParticles can also be endowed with photoresponsive properties, which positions them as interesting nanovectors for PDT.

Study of the thermoluminescence properties of γ and UV-C irradiated Li3PO4: Dy synthesized by solid state diffusion method

This paper reports the thermoluminescence (TL) properties of Li3PO4 doped with rare earth Dy3+ ions. The solid state diffusion method is used to synthesize phosphors with varying concentrations of the dopant (0.1, 0.2, 0.3, 0.4 and 0.5 mol%). Characterization of the samples is performed using X-ray diffraction (XRD), Fourier Transform Infrared-Attenuated Total Reflection spectroscopy (FTIR-ATR) and Scanning Electron Microscopy (SEM). Samples are irradiated with γ rays in the dose range of 10 Gy to 6 kGy and by UV-C rays (254 nm) for exposure duration ranging from 0.5 to 5 h. Maximum TL intensity in both cases is observed for the phosphor doped with 0.2 mol% Dy3+. While a linear TL response is found for the entire duration of UV-C irradiation, the dose response for γ irradiation stays linear upto 3 kGy for the high temperature peak at 335∘C. Appreciable repeatability values are found (for both γ and UV-C irradiated samples) and significantly low fading (for the UV-C irradiated phosphor) is reported. The computerized glow curve deconvolution has been done using an R-package, “tgcd: Thermoluminescence Glow Curve Deconvolution” by assuming the Kitis general order kinetics model. Chen’s peak shape method is utilized to extract trapping parameters such as the order of kinetics (b), shape factor (μg), frequency factor (s), activation energy (E) and trap density (n0). Various promising properties of this material are found suggesting that it could be used as a TL dosimeter.

Photosensitiser-incorporated microparticles for photodynamic inactivation of bacteria.

Antimicrobial resistance is an ever-growing global concern, making the development of alternative antimicrobial agents and techniques an urgent priority to protect public health. Antimicrobial photodynamic therapy (aPDT) is one such promising alternative, which harnesses the cytotoxic action of reactive oxygen species (ROS) generated upon irradiation of photosensitisers (PSs) with visible light to destroy microorganisms. In this study we report a convenient and facile method to produce highly photoactive antimicrobial microparticles, exhibiting minimal PS leaching, and examine the effect of particle size on antimicrobial activity. A ball milling technique produced a range of sizes of anionic p(HEMA-co-MAA) microparticles, providing large surface areas available for electrostatic attachment of the cationic PS, Toluidine Blue O (TBO). The TBO-incorporated microparticles showed a size-dependent effect on antimicrobial activity, with a decrease in microparticle size resulting in an increase in the bacterial reductions achieved when irradiated with red light. The >6 log10Pseudomonas aeruginosa and Staphylococcus aureus reductions (>99.9999%) achieved within 30 and 60min, respectively, by TBO-incorporated >90μm microparticles were attributed to the cytotoxic action of the ROS generated by TBO molecules bound to the microparticles, with no PS leaching from these particles detected over this timeframe. TBO-incorporated microparticles capable of significantly reducing the bioburden of solutions with short durations of low intensity red light irradiation and minimal leaching present an attractive platform for various antimicrobial applications.

Induction of Protocorm-Like Bodies (PLBs) Phalaenopsis spp. Hybrids Mutation through Ultraviolet Irradiation (UV254) and Ethyl Methane Sulfonate (EMS)

Phalaenopsis sp. is the most-produced orchid species in Indonesia. Compared to conventional breeding, mutation induction by using mutagens, such as Ultraviolet Light-C (λ = 254 nm) (UV254) and Ethyl Methane Sulfonate (EMS), could probably result in new superior orchid variants. This research aims to get some mutants with phenotypes that have visual differences in the Phalaenopsis spp. hybrids wild type. There were 4 durations of UV254 irradiation: 5’ on, 85’ off; 10’ on, 80’ off (1 day and 7 days for each treatment); 4 concentrations of EMS used in this research: 0.05%; 0.06%; 0.07%; 0.08% for 6 hours of immersion; selected UV254 irradiation (5’ on, 85’ off (7 days)) combined with these concentrations. UV254 irradiation treatment (5’ on, 85’ off (1 day and 7 days); 10’ on, 80’ off (7 days)) resulted in some mutants with leaf phenotypes that were visually different from the wild type; 0.05% EMS treatment resulted in PLBs mutant with a visually larger size than the wild type; 0.08% EMS treatment and combination treatments (for EMS 0.05% and 0.08% for each treatment) resulted in non-growing albino PLBs. Hence, mutation induction using UV254 and EMS in this research produced several most likely mutants having visual differences that may be more desirable than the wild type.

Parametric investigation of multi-pulsed cryogen spray cooling for skin protection during hyperthermal laser lipolysis through in vitro experiment and numerical simulation

Nowadays laser lipolysis has been a widely accepted modality to remove fat. Transcutaneous hyperthermal laser lipolysis has attracted researchers’ interest because of its non-invasive nature and high efficiency. However, the possible thermal damage of skin tissue owing to the competitive absorption of laser energy between water and adipose tissue limits its application, which necessitates the development of efficient skin cooling technology. An in vitro laser experiment of streaky pork under 1210 nm laser irradiation with different power (E) and irradiation (t) proved that the epidermis temperature will exceed the safety threshold of 47 °C when E = 6W and t ≥ 5s, or E ≥ 9W and t ≥ 3s. To protect skin from thermal injury, the multi-pulsed cryogen spraying cooling (MP-CSC) by using R134a was introduced and numerical simulation was conducted to optimize cooling and laser parameters by simplifying the skin tissue to a multi-layered model. The simulation results suggest that hyperthermal laser lipolysis with a power of 6W∼9W and an irradiation duration of 7s can be realized for an area as large as 3 × 7.2 mm2, by coupling MP-CSC with a pulse duration of 10 ms, a pulse delay of 2000 ms and a pulse number of 5. In this sense, the MP-CSC has great potential to prompt transcutaneous hyperthermal laser lipolysis.

Synthesis and Characterisation of Self-Cleaning TiO2/PES Mixed Matrix Membranes in the Removal of Humic Acid.

Membrane application is widespread in water filtration to remove natural organic matter (NOM), especially humic acid. However, there is a significant concern in membrane filtration, which is fouling, which will cause a reduction in the membrane life span, a high energy requirement, and a loss in product quality. Therefore, the effect of a TiO2/PES mixed matrix membrane on different concentrations of TiO2 photocatalyst and different durations of UV irradiation was studied in removing humic acid to determine the anti-fouling and self-cleaning effects. The TiO2 photocatalyst and TiO2/PES mixed matrix membrane synthesised were characterised using attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy, X-ray powder diffraction (XRD), scanning electron microscope (SEM), contact angle, and porosity. The performances of TiO2/PES membranes of 0 wt.%, 1 wt.%, 3 wt.%, and 5 wt.% were evaluated via a cross-flow filtration system regarding anti-fouling and self-cleaning effects. After that, all the membranes were irradiated under UV for either 2, 10, or 20 min. A TiO2/PES mixed matrix membrane of 3 wt.% was proved to have the best anti-fouling and self-cleaning effect with improved hydrophilicity. The optimum duration for UV irradiation of the TiO2/PES mixed matrix membrane was 20 min. Furthermore, the fouling behaviour of mixed matrix membranes was fitted to the intermediate blocking model. Adding TiO2 photocatalyst into the PES membrane enhanced the anti-fouling and self-cleaning properties.

Sustainable Campus Policy Strategy in Estimating CO2 Emissions at the Universitas Negeri Semarang, Indonesia

In the fight against global warming, various options for reducing CO2 emissions are being implemented on campus. Furthermore, the management of campus sustainability at the Universitas Negeri Semarang (UNNES), Central Java, Indonesia, should be supported by accurate forecasts of electrical energy consumption. Therefore, this research aims to develop a predictive model to forecast the consumption of electrical energy in reducing CO2 emissions and to determine the factors triggering the increase. The prediction model is developed using Back Propagation Neural Network Artificial (BP-ANN) architecture. Furthermore, the data on the occupancy of lecturers and education staff as well as on students was obtained from the University's staffing and student affairs bureau. Climatic data such as temperature, humidity, wind speed, the duration of irradiation, and the average intensity of solar radiation were obtained per month from the Meteorology, Climatology, and Geophysics Agency of Semarang, Central Java for the 2013-2019 period as input data. The results of the empirical analysis showed an increase in electrical energy consumption from 2020 to 2025. In March, the consumption decreased but increased from April to June and decreased in July. It then increased until November and December, and it decreased every year. The results of CO2 emissions calculated by considering the emission factors from Indonesia's RUPTL-PLN in 2020-2025 showed an increase in electrical energy consumption and the ecological consequences affecting the campus area. Furthermore, the main factors causing the high consumption of electrical energy are the occupancy rate, lecturers, students, and campus employees, as well as local climate influences such as temperature, humidity, wind speed, duration of solar radiation, and intensity of solar radiation. Therefore, developing guidelines to reduce power consumption on campus should be a priority