FeCl3 Research Articles

Enhanced Removal of Polystyrene Microplastics from Water Through Coagulation Using Polyaluminum Ferric Chloride with Coagulant Aids

Enhanced Removal of Polystyrene Microplastics from Water Through Coagulation Using Polyaluminum Ferric Chloride with Coagulant Aids

Sodium and potassium ferrocyanide derived Prussian blue pigment

Purpose This study aims to synthesize Prussian blue {FeIII4[FeII(CN)6]3} pigment by reacting ferric chloride with different ferrocyanides through the same procedure. The influence of the ferrocyanide used on resulting pigment properties is studied. Design/methodology/approach Prussian blue is commonly synthesized by direct or indirect methods, through iron salt and ferrocyanide/ferricyanide reactions. In this study, the direct, single-step process was pursued by dropwise addition of the ferrocyanide into ferric chloride (both as aqueous solutions). Two batches – (K-PB) and (Na-PB) – were prepared by using potassium ferrocyanide and sodium ferrocyanide, respectively. The development of pigment was confirmed by an identification test and characterized by spectroscopic techniques. Pigment properties were determined, and light fastness was observed for acrylic emulsion films incorporating dispersed pigment. Findings The two pigments differed mainly in elemental detection owing to the dissimilar ferrocyanide being used; IR spectroscopy where only (Na-PB) showed peaks indicating water molecules; and bleeding tendency where (K-PB) was water soluble whereas (Na-PB) was not. The pigment exhibited remarkable blue colour and good bleeding resistance in several solvents and showed no fading in 24 h of light exposure though oil absorption values were high. Originality/value This article is a comparative study of Prussian blue pigment properties obtained using different ferrocyanides. The dissimilarity in the extent of water solubility will influence potential applications as a colourant in paints and inks. K-PB would be advantageous in aqueous formulations to confer a blue colour without any dispersing aid but unfavourable in systems where other coats are water-based due to their bleeding tendency.

An Evaluation of the Beneficial Effects of Polyamide 6's Thermal Stabilization by Ferric Chloride Complexation as a Novel Carbon Fiber Precursor

This study investigated the impact of stabilization time on pretreated polyamide 6 (PA6) fibers using various analytical techniques, including thermal analysis (TGA and DSC), infrared (IR) spectroscopy, X-ray diffraction (XRD), tensile testing, and density measurements. The two-step atmospheric air-based stabilization process for pretreated PA6 multifilament bundles involved initial thermal stabilization at 170 °C in an air atmosphere after ferric chloride impregnation, followed by a second step of thermal stabilization at 245 °C. Ferric chloride impregnation followed by thermal stabilization in an air atmosphere resulted in crucial structural transformations. The density values of the samples increased following thermal stabilization, accompanied by a decrease in tensile values. Ferric chloride pretreated and thermally stabilized PA6 fibers were found to be fully stabilized after 120 min of stabilization before the carbonization stage. The findings obtained from the DSC, XRD, and IR spectroscopy methods indicated the occurrence of disordering phases due to the scission of hydrogen bonds. The TGA findings showed significant increases in carbon yield percentages at 500 °C and 850 °C, reaching 71.4% and 63.5%, respectively, for the sample heat treated at 245 °C for 120 min. The addition of ferric chloride is expected to potentially reduce processing costs for final carbon fiber production by decreasing the time required for the thermal stabilization of PA6.

The characteristics of adsorption Cr(VI) by iron-modified and iron-doped phosphorus-based biochar biochar

ABSTRACT In this study, we evaluated the effect of the modification of biochar on the adsorption of Cr(VI) under weakly acidic conditions. Sesame straw biochar (BC) was modified by treatment with ferric chloride to produce iron-modified biochar (FBC) and ferric chloride and chlorapatite to produce iron-doped chlorapatite-modified biochar (FBCP). Analysis by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) showed that the adsorption mechanism of Cr(VI) by FBC and FBCP was reduction, physical adsorption, ion exchange, and functional group complexation. Experiments were performed to evaluate the kinetic, isothermal, and thermodynamic characteristics of adsorption, demonstrating that the adsorption of Cr(VI) by FBC and FBCP was a spontaneous endothermic reaction, consistent with the pseudo-second-order kinetic model and Langmuir model, and the process was dominated by monolayer chemical adsorption. The Langmuir model revealed maximum saturated adsorption capacities for Cr(VI) of 7.907 and 12.625 mg/g by FBC and FBCP, respectively, equating to 4.06 and 6.48 times the maximum saturated adsorption capacity of BC, respectively. Compared with FBC, the phosphate ions in FBCP also co-precipitated with Cr(III), further improving the removal efficiency of pollutants.

Optimized process intensification through dynamic performance simulation and evaluation of treatment alternatives for a wastewater treatment plant in Toronto

In this study, a comprehensive plant-wide model of the North Toronto Treatment Plant (NTTP) was developed, focusing on improving operational efficiency and capacity utilization. NTTP, with a rated capacity of 45 MLD, is currently operating at about 18 MLD with treatment processes including physical units (incorporating four primary settling tanks), chemical precipitation (for phosphorus removal using ferrous chloride), and biological processes (utilizing eight plug-flow conventional activated sludge (CAS) aeration tanks), and two sets of final clarifiers. Utilizing Biowin 6.2, the study constructed and calibrated a mechanistic model based on historical plant records and extensive sampling campaign data gathered from July to August 2022. The performance of various process configurations under different operational and seasonal conditions was evaluated. It was observed that the Ludzack-Ettinger (L-E) configuration demonstrated enhanced performance in terms of Environmental Compliance Approval (ECA) objectives and cost-efficiency compared to the CAS process. However, the L-E configuration posed challenges related to the final clarifier loading. The State Point Analysis (SPA) conducted within the study emphasized the effectiveness of the Membrane Aerated Bioreactor (MABR) in producing high-quality effluent, while also reducing the burden on the final clarifiers. This research provides a foundation for potential upgrades to NTTP, leveraging existing infrastructure to approach its full rated capacity while maintaining adherence to current ECA objectives.

A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity

BackgroundProtease-activated receptor 4 (PAR4) mediates thrombin signaling on platelets and other cells. Our recent structural studies demonstrated that a single nucleotide polymorphism in extracellular loop 3 and PAR4-P310L (rs2227376) leads to a hyporeactive receptor. ObjectivesThe goal of this study was to determine how the hyporeactive PAR4 variant in extracellular loop 3 impacts platelet function in vivo using a novel knock-in mouse model (PAR4-322L). MethodsA point mutation was introduced into the PAR4 gene F2rl3 via CRISPR/Cas9 to create PAR4-P322L, the mouse homolog to human PAR4-P310L. Platelet response to PAR4 activation peptide (AYPGKF), thrombin, ADP, and convulxin was monitored by αIIbβ3 integrin activation and P-selectin translocation using flow cytometry or platelet aggregation. In vivo responses were determined by the tail bleeding assay and the ferric chloride–induced carotid artery injury model. ResultsPAR4-P/L and PAR4-L/L platelets had a reduced response to AYPGKF and thrombin measured by P-selectin translocation or αIIbβ3 activation. The response to ADP and convulxin was unchanged among genotypes. In addition, both PAR4-P/L and PAR4-L/L platelets showed a reduced response to thrombin in aggregation studies. There was an increase in the tail bleeding time for PAR4-L/L mice. The PAR4-P/L and PAR4-L/L mice both showed an extended time to arterial thrombosis. ConclusionPAR4-322L significantly reduced platelet responsiveness to AYPGKF and thrombin, which is in agreement with our previous structural and cell signaling studies. In addition, PAR4-322L had prolonged arterial thrombosis time. Our mouse model provides a foundation to further evaluate the role of PAR4 in other pathophysiological contexts.

Mesoscopic combinatorial design of anisotropic graphitic carbon with ordered porous frameworks for thermoelectric conversion

The incorporation of carbon materials can effectively enhance the performance of thermoelectric materials. By optimizing the thermoelectric properties of the carbon scaffold, it is possible to further improve the thermoelectric performance of the prepared carbon-based composites. To elevate the thermoelectric performance of the carbon scaffold, this work introduces a novel mesoscopic design strategy, utilizing natural flake graphite to create a three-dimensional ordered porous framework. Highly controllable anisotropic conductivity and thermal conductivity of the porous graphite skeleton were achieved, by combining sizable sodium chlorine templates (37.5–250 μm) with a natural flake graphite matrix (50–150 μm). A porous graphite with high electrical conductivity and low thermal conductivity along the vertical axis was obtained by carefully regulating the parameters. The sample demonstrated exceptional thermoelectric conversion performance, achieving a thermoelectric power factor of 12.2 μW m−1 K−2 and a figure of merit value of 28.3 × 10−4. Furthermore, the thermoelectric property of the samples could be greatly improved by adding a small amount of ferric chloride, with a thermoelectric power factor reaching 41.9 × 10−4 and a thermoelectric figure of merit reaching 81.4 μW m−1 K−2. This work provides an effective scheme for the mesoscopic regulation of porous graphite carbon structures and offers a new strategy for enhancing the performance of thermoelectric generators.

Optimizing Typha biochar with phosphoric acid modification and ferric chloride impregnation for hexavalent chromium remediation in water and soil

Considering the persistent and covert nature of heavy metal soil contamination, the sustainable development of ecological environments and food safety is at significant risk. Our study focuses on remediating soils contaminated with chromium (Cr); we introduce an advanced remediation material, iron oxide phosphoric acid-loaded activated biochar (HFBC), synthesized through pyrolysis. This HFBC displays greater microporosity, fewer impurities, and enhanced efficiency for the remediation process. Our research utilized a comprehensive set of analytical techniques, including Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), and X-ray Photoelectron Spectroscopy (XPS), alongside adsorption studies to elucidate the Cr removal mechanism. The effectiveness of HFBC in remediation was influenced by several factors: the pH level, dosage of HFBC, the initial concentration of Cr, and the ambient temperature. Our results indicated an optimal chromium (VI) adsorption capacity of 55.5 mg/g by HFBC at a pH of 6.0 and a temperature of 25 °C, with the process adhering to the pseudo-second-order kinetic model and the Langmuir adsorption isotherm, thus suggesting spontaneity in the uptake method. Moreover, this mechanism encompasses both adsorption and reduction reactions. Using HFBC in pot experiments with cabbage indicated not only an increase in soil pH and cation exchange capacity (CEC), but also a surge in bacterial community abundance. Significant reductions in bioavailable chromium were also recorded. Interestingly, HFBC addition bolstered the growth of cabbage, while concurrently diminishing chromium accumulation within the plant, particularly notable as the HFBC application rate increased. In summation, the HFBC produced in our study has demonstrated convincing efficacy in removing chromium from aqueous solutions and soil. Moreover, the positive agronomic implications of its use, such as enhanced plant growth and reduced heavy metal uptake by plants, indicate its high potential for operational value in the domain of environmental remediation of heavy metals.

Ferric- and calcium-loaded red soil assist colonization of submerged macrophyte for the in-situ remediation of eutrophic shallow lake: From mesocosm experiment to field enclosure application

Eutrophication and its resulting harmful algal blooms greatly reduce the ecosystem services of natural waters. The use of modified clay materials to assist the phytoremediation of eutrophic water is a promising technique. In this study, ferric chloride and calcium hydroxide were respectively loaded on red soil for algal flocculation and phosphorus inactivation. A two-by-two factorial mesocosm experiment with and without the application of ferric- and calcium- loaded red soil (FA), and with and without planting the submerged macrophyte Vallisneria natans was conducted for the in-situ repair of eutrophic water and sediment. Furthermore, field enclosure application was carried out to verify the feasibility of the technology. At the end of the mesocosm experiment, the total phosphorus, total nitrogen, and ammonia nitrogen concentrations in water were reduced by 81.8 %, 63.3 %, and 62.0 %, respectively, and orthophosphate phosphorus concentration in the sediment-water interface decreased by 90.2 % in the FA + V. natans group compared with those in the control group. The concentration and proportion of chlorophyll-a in cyanobacteria decreased by 89.8 % and 71.2 %, respectively, in the FA + V. natans group. The content of active phosphorus in V. natans decreased and that of inert phosphorus increased in the FA + V. natans group, compared with those in the V. natans alone group, thus may reducing the risk of phosphorus release after decomposing of V. natans. The sediment bacterial diversity index did not change significantly among treatments. Field enclosure application have also been successful, with chlorophyll-a concentration in the water of treated enclosure decreased from above 200 μg/L to below 10 μg/L, and phosphorus concentration in the water decreased from >0.6 mg/L to <0.02 mg/L. These results demonstrated that the FA in combination with submerged macrophyte planting had great potential for the in-situ remediation of eutrophic water, especially those with severe algal blooms.

Phytochemical composition and in vitro antioxidant and antimicrobial activities of Bersama abyssinica F. seed extracts

Medicinal plants can be potential sources of therapeutic agents. Traditional healers use a medicinal plant from Ethiopia, Bersama abyssinica Fresen, to treat various diseases. This study aimed to investigate the phytochemical components and antioxidant and antimicrobial activities of B. abyssinica seed extracts (BASE). Gas chromatography coupled to mass spectroscopy (GC–MS) analysis was used to determine the phytochemical compositions of BASE. The antioxidant activities were assessed by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay, thiobarbituric acid-reactive species (TBARS) assay, ferric chloride reducing assay and hydroxyl scavenging capacity assay. Antimicrobial activity was investigated using the agar well diffusion method. Phytochemical screening showed the presence of saponins, glycosides, tannins, steroids, phenols, flavonoids, terpenoids, and alkaloids. GC–MS analysis revealed the presence of 30 volatile compounds; α-pinene (23.85%), eucalyptol (20.74%), β-pinene (5.75%), d-limonene (4.05%), and o-cymene (5.02%). DPPH-induced free radical scavenging (IC50 = 8.78), TBARS (IC50 = 0.55 µg/mL), and hydroxyl radicals’ scavenging capacities assays (IC50 = 329.23) demonstrated high antioxidant effects of BASE. Reducing power was determined based on Fe3+–Fe2+ transformation in the presence of extract. BASE was found to show promising antibacterial activity against S. aureus, E. coli, and P. aeruginosa (zone of inhibition 15.7 ± 2.5 mm, 16.0 ± 0.0 mm, and 16.7 ± 1.5 mm, respectively), but excellent antifungal activities against C. albican and M. furfur (zone of inhibition 22.0 ± 2.0 mm and 22.0 ± 4.0 mm, respectively). The seeds of B. abyssinica grown in Ethiopia possess high antioxidant potential, promising antibacterial and superior antifungal activity. Therefore, seeds of B. abyssinica provide a potential source for drug discovery.

A new iron battery technology: Charge-discharge mechanism of ferrous chloride and ferric oxide electrolyte in all solid-state iron-graphite batteries

This study investigates a Fe/SSE/GF battery. Iron (Fe) as cathode material contains higher electrical capacity and competitive advantages. The solid-state electrolyte (SSE) material is sodium silicate powder mixed with iron compound powders. There are four types of iron compounds: 1) iron oxide, 2) chlorinated/Na-rich iron oxide, 3) Cl-rich iron oxide, 4) ferrous chloride, which are compared with sodium silicate powder. The negative electrode material is graphite film (GF). According to experiments, converting iron into iron oxide or ferric chloride can enhance battery capacity (beyond 200 mAh/g) and cycle life. The reliability of the Fe/SSE/GF battery was assessed by substituting sodium silicate powder with an iron compound electrolyte and adding binder (Polyvinyl Alcohol, PVA) into powder to enhance the performance of Fe/SSE/GF. This experimental research is not only innovative but also represents a significant milestone in the field of solid-state energy storage.

Upper Rim-Bridged Calix[4]arenes via Cyclization of meta Alkynyl Intermediates with Diphenyl Diselenide.

A Sonogashira coupling of meta-iodocalix[4]arene with various terminal acetylenes confirmed that the meta position of calixarene is well addressable, and that both thermal and microwave protocols led to good yields of alkynylcalixarenes. Alkynes thus obtained were subjected to the ferric chloride and diphenyl diselenide-promoted electrophilic closure. It turns out that the calix[4]arenes give completely different bridging products than those described for the non-macrocyclic starting compounds. This can be demonstrated not only by the isolation of products with a six-membered ring (6-exo-dig), but mainly by the smooth formation of the 5-endo-dig cyclization, which has never been observed in the aliphatic series. An attempt at electrocyclization led to a high yield of the 1,2-diketone (oxidation of the starting alkyne), again in contrast to the reaction described for the acyclic derivatives. The structures of the unexpected products were unequivocally established by X-ray analysis and clearly demonstrate how the preorganized macrocyclic skeleton favors a completely different regioselectivity of cyclization reactions compared to common aliphatic compounds.

Impact of Metal Salt Oxidants and Preparation Technology on Efficacy of Bacterial Cellulose/Polypyrrole Flexible Conductive Fiber Membranes.

In this study, we investigated the preparation and characterization of flexible conductive fiber membranes (BC/PPy) using different metal salt oxidants on bacterial cellulose (BC) and pyrrole (Py) in the in situ polymerization and co-blended methods, respectively. The effects of these oxidants, namely, ferric chloride hexahydrate (FeCl3·6H2O) and silver nitrate (AgNO3), on the structural characterization, conductivity, resistance value and thermal stability of the resulting materials were assessed by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). A comparative study revealed that the BC/PPy conductive fiber membrane prepared using FeCl3·6H2O as the oxidant had a resistance value of 12 Ω, while the BC/PPy conductive fiber membrane prepared using AgNO3 as the oxidant had an electrical resistance value of 130 Ω. The conductivity of the same molar ratio of BC/PPy prepared using FeCl3·6H2O as an oxidant was 10 times higher than that of the BC/PPy prepared using AgNO3 as an oxidant. Meanwhile, the resistance values of the conductive fiber membranes prepared from BC and PPy by the co-blended method were much higher than the BC/PPy prepared by in situ polymerization. SEM and XPS analyses revealed that when FeCl3·6H2O was used as the oxidant, the Fe-doped polypyrrole conductive particles could form uniform and dense conductive layers on the BC nanofiber surfaces. These two metal salt oxidants demonstrated differences in the binding sites between PPy and BC.

Acid content sensitive colorimetry of poly-N-phenyl-o-phenylenediamine for state of charge determination of lead-acid battery

The ex-situ colorimetric method of battery acid estimation was developed using poly-N-phenyl-o-phenylenediamine (PPOPD) to accurately determine the lead acid battery's state of charge (SoC). PPOPD was synthesized by the in-situ oxidative chemical polymerization of N-phenyl-o-phenylenediamine monomer (POPD) using ferric chloride as an oxidizing agent in ethanol solvent. The UV–visible absorption peak of PPOPD in acidic solutions at 518 nm showed a sharp positive linear slope with increased acid content. The charging or discharging mechanism of the battery produces changes in battery acid content. A fully charged lead-acid battery contains approximately 39.7 % sulphuric acid, whereas its acid content decreases by approximately 10 % on discharge. The PPOPD polymer showed a change in absorbance with a change in the lead-acid battery's acid percentage, which can be correlated with the state of charge. The absorbance of PPOPD solution was calibrated linearly with the sulphuric acid percentage (6–40 %), a similar acid range produced inside the battery during charging or discharging. The absorbance of PPOPD solution obtained in 10 % and 40 % sulphuric acid at 518 nm was set as the lower and upper limits (Amin and Amax) respectively for SoC determination. Therefore, the state of charge in any lead-acid battery under investigation can be determined by measuring the absorbance of the PPOPD solution. The state of charge obtained from the colorimetric method was compared with an open circuit voltage method using a 12 V lead-acid battery.

Polymer Supported Ferric Chloride as Heterogeneous Catalyst for Three Component Biginelli Reaction

Polymer Supported Ferric Chloride as Heterogeneous Catalyst for Three Component Biginelli Reaction

Exploring the Influence of Morphology on Bipolaron-Polaron Ratios and Conductivity in Polypyrrole in the Presence of Surfactants.

This research aims to deepen the understanding of the relationship between conductivity and morphology in polypyrrole (PPy) via a comparison of the bipolaron to polaron ratios with a focus on the C-H deformation area. PPy samples were synthesized with different surfactants: sodium dodecyl sulfate (SDS), cetyltrimethylammonium bromide (CTAB), and tween 80 (TW). This study revealed that SDS significantly altered the bipolaron and polaron in the C-H deformation region and showed higher conductivity than other surfactants. Notably, the morphological shifts to a sheet-like structure when using ammonium sulfate (APS) contrasted with the particle-like form observed with ferric chloride (FeCl3). These results showed that if the oxidant changed, the bipolaron and polaron ratios in C-H deformation were unrelated to PPy morphology. However, this work showed a consistent relationship between SDS use, the bipolaron and polaron ratios in the C-H deformation, and the conductivity properties. Moreover, the natural positive charge of PPy and negatively charged SDS molecules may lead to an electrostatic interaction between PPy and SDS. This work assumes that this interaction might cause the transformation of polaron to bipolaron in the C-H deformation region, resulting in improved conductivity of PPy. This work offers more support for the future investigation of PPy characteristics.

Eco-friendly wastewater treatment using a crab shell-based liquid bio-coagulant: Multi-criteria decision analysis related to different pollutants separation

The protein-rich liquid resulting from the deproteinization step of the chitin/chitosan production process is proposed as a novel wastewater bio-coagulant. The raw material for producing the bio-coagulant is the crab shell contained in discarded fishery by-products. The protein content of the liquid, determined by OPA assay, was 31.6 mg/L. FTIR spectra proved the presence of chitin, and SEM images showed the presence of a nanoparticulated chito-protein complex in the liquid. Coagulation tests were performed with fisheries wastewater, in which the influence of different parameters, such as the bio-coagulant dose, the pH, the agitation speed, and the settling time, on the effectiveness of the bio-coagulant were investigated. Since different parameters with values in wide ranges may affect the fisheries wastewater treatment by the use of the new liquid bio-coagulant, a multicriterial optimization analysis based on Box-Behnken and response surface method (RSM) was applied. The optimal removal degrees, in terms of turbidity (98.91%), BOD5 (92.05%), and COD (78.92%) were achieved at a bio-coagulant dosage of 17.5 mL/L of fish processing wastewater (FPW) at pH 11.3 and temperature of 25°C. A good fit resulted from the experimental data, the Box-Behnken regression models, and response surface-calculated data. The results revealed new bio-coagulant effectiveness similar or superior to the commonly used chemical coagulants (ferric chloride, aluminum sulfate) and even to commercial chitosan. The obtained data indicate that the new natural liquid bio-coagulant is environmentally friendly and suitable for fisheries wastewater treatment.

Synergistic Addition of Polymer, Ferric Chloride, and Hydrogen Peroxide to Enhance the Post-treatment Efficiency of Thermophilic Digestate

Synergistic Addition of Polymer, Ferric Chloride, and Hydrogen Peroxide to Enhance the Post-treatment Efficiency of Thermophilic Digestate

Catalytic action of hydronium-ion in rice straw pretreatment and enhancement of enzymatic hydrolysis and ethanol production

The present investigation will focus on the catalytic effect of hydronium ion during liquid-water/ dilute sulfuric acid/ferric chloride pretreatment (LWP/ SAP/ FCP) on the hydrolysate and pretreated rice straw. The overall pretreatment process has been represented as a sequential catalytic reactions. The temperature range of pretreatment is varied in the range of 140–180 °C and the concentration of dilute sulfuric acid and ferric chloride is 0.1 M. The first order rate constants of xylan and glucan degradation have been determined for LWP/ SAP/ FCP. The maximum xylan and glucan conversion of 96.8% w/wand 31.4%w/w respectively are achieved for FCP at 180 °C. Xylose, glucose, furfural, 5-hydroxymethyl furfural, acetic acid and formic acid appear as the main products for all pretreatments. Only in case of FCP levulinic acid also appears as a hydrolysis product. The thermal characteristics, functional groups, crystallinity, surface morphology of untreated and pretreated rice straw have been evaluated. Among all pretreatment processes under study, the highest values of glucose yield of 78.96% (w/w) using enzymatic hydrolysis and 83.79% of theoretical yield of ethanol using Saccharomyces cerevisiae have been achieved for ferric chloride pretreatment.

Facile Green Synthesis of Iron Oxide Nanoparticles and Their Impact on Cytotoxicity, Antioxidative Properties and Bactericidal Activity.

Bioreductive processes are quite potent, effective and affordable for the synthesis of green nanoparticles (NPs), as compared to the physical and chemical methods. The present study aimed to evaluate the bactericidal, antioxidative and anticancer activity of turmeric rhizome-iron oxide nanoparticles (FeONPs) derived from the turmeric rhizome (Curcuma amada) using ferric chloride as a precursor. With focusing on the manufacture of FeONPs via green approach, we characterized the NPs using FTIR, FT-Vis, DLS, and UV-Vis spectroscopy. The produced particles were tested for antibacterial, antioxidant, and anticancer properties. The synthesized NPs were also examined using the MDA-MB-231 human epithelial breast cancer cell line and NCI-60 cancer cell lines. The antioxidant activity of TR-FeONPs was concentration-dependent. The scavenging activity of TR-FeONPs was 76.09% at a concentration of 140 µg/ml. Using different concentrations of TR-FeONPs in the MTT assay against the MDA-MB-231 cell line indicated a reduction of less than 50% in cell viability at 125 µg/ml. Moreover, TR-FeONPs exhibited an effective bactericidal property. The gTR-FeONPs synthesized bioreductively were found to be effective in renal cancer, UO-31 cell line, with GI50 value of 66.64%. Our study showcases a sustainable method based on green chemistry principles to produce FeONPs utilizing turmeric rhizome. We anticipate that the FeONPs produced through this biosynthesis process could serve as a promising drug delivery system in cancer treatment and as an effective antimicrobial agent against various diseases.