Iron Deficiency In Adolescents Research Articles

Sex Differences in Iron Stores of Adolescents

SummaryWe evaluated iron status and its determinants in healthy adolescents. Fasting morning blood samples from a school‐based cross‐sectional study were analyzed for serum ferritin (SF), serum iron, total iron‐binding capacity, and circulating transferrin receptors. Physical development, chronic disease, medication, dietary intake, and physical activity were assessed using clinical examination, questionnaires, and 7‐day records. The risk of having low serum ferritin values was estimated using bivariate and multivariate regression. Subjects were 867 healthy Swedish adolescents, 14− and 17‐year‐olds (472 boys and 395 girls). SF values increased with pubertal stage in boys but not in girls. Five percent of the boys and 15% of the girls had SF values <12 μg/L. Of the 17‐year‐old boys, 7% compared to 1% of the 17‐year‐old girls had SF values > 100 μg/L. Forty‐one percent of cases with SF values >12 μg/L had serum iron values < 15 μM, and 22% had transferrin saturation values <16%. Mean total iron intakes of the boys were high [1.6 times recommended daily allowance (RDA)] and mean intakes of the girls were adequate (0.9 times RDA). Low heme iron intakes increased the risk of low iron stores (<12 μg/L) in girls but not in boys. Total iron intake or other dietary factors, physical development, or level of physical activity did not influence the risk of low SF. The findings of this study suggest that the differences in iron status between boys and girls in adolescence results primarily from biological differences other than menstrual bleeding or insufficient iron intake. Furthermore, the results question the role of SF as an indicator of iron deficiency in adolescence, in particular if age and sex are not taken into consideration. We suggest that different reference values for SF, including the cut‐off limit for low SF, adjusted for age and sex, should be considered. The high iron intakes and corresponding high SF values found in the older boys are noticeable in light of the possible negative health consequences of iron overload.

Prevalence of Iron Deficiency in Swedish Adolescents

The prevalence of iron deficiency was determined in Göteborg, Sweden, in a sample of 15- to 16-y-old girls (n = 220) and boys (n = 207) using serum ferritin (SF). In a recent study in women on the relationship between SF and stainable bone marrow iron, it was established that at a cutoff value for SF of < 16 micrograms/L in 75% of women with no iron stores SF concentration was below this value (sensitivity 75%), whereas in 98% of iron-replete women it was above this cutoff value (specificity 98%). The present study showed that in 40% of the girls and 15% of the boys SF was below this cutoff value, indicating iron deficiency. Low SF concentration was associated with significant decreases in transferrin saturation, Hb concentration, mean corpuscular Hb, and mean corpuscular volume. The results from this cross-sectional study showed that, with decreasing SF, the decrease of values for these parameters occurred already before SF had reached the level 16 micrograms/L, suggesting that SF can be validly used as a single criterion of iron deficiency. Using the cutoff value SF < 16 micrograms/L, the figures for the prevalence of iron deficiency in adolescents in different countries were compared and found to be rather similar in Australia, Canada, the United States, and Sweden. High iron requirements combined with the present low-energy life-style leading to an insufficient supply of dietary iron may be a reasonable main explanation for the paradoxical, high prevalence of iron deficiency in adolescents in affluent societies.

Iron Deficiency in Adolescents and Young Adults.

In brief After childhood, iron deficiency is mainly a problem in females, but it also occurs in males aged 11 to 14 years. Inadequate dietary intake of iron is the major cause of iron deficiency, but factors such as gastrointestinal (GI) blood loss may contribute to this problem. Mild anemia may impair sports performance, and some research suggests that iron deficiency without anemia also has an adverse effect. The diagnosis of iron deficiency should be based on the patient's serum ferritin and hemoglobin concentrations. Treatment requires therapeutic doses of oral ferrous iron for several months.

The Frequency of Platelet Count Abnormality among Junior High School Students and Quantitative, Qualitative Changes of Platelets during Treatment for Adolescent Iron Deficiency Anemia

The Frequency of Platelet Count Abnormality among Junior High School Students and Quantitative, Qualitative Changes of Platelets during Treatment for Adolescent Iron Deficiency Anemia

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

Iron deficiency in adolescents.

思春期の鉄欠乏症に関する研究

思春期の鉄欠乏症に関する研究