The present prospective study evaluates the results of therapy in pyriform fossa cancer patiens. Primary radical surgery including ipsilateral radical neck dissection gave distinctly superior results than the radiation-failed-salvage surgery group (63% varsus 30%). The poor results in the latter group may be attributed to the delay in performing surgery, resulting in larger size of primary lesions and the fact that radiotherapy may impair our ability to determine adequate resected margins. We new favour a protocol consisting of primary radical surgery followed in a planned manner by postoperative radiotherapy in treating these cancers.
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