Introduction Of Blood Research Articles

Susceptibility of the "Gopher," Citellus richardsonii (Sabine), to Leptospira icterohemorrhagi .

SummaryEvidence is presented of the susceptibility of the gopher or Richardson ground-squirrel, Citellus richardsonii (Sabine), to the etiological agent of Weil's disease, Leptospira ictero-hemorrhagiœ. Two series of 5 and 15 passages through gophers, respectively, were effected by the parenteral introduction of blood or tissue-suspensions. The organisms were tested in guinea pigs following the serial passages in gophers; no changes in pathogenicity were noted. Passage was also accomplished by permitting normal gophers to feed on infected gophers, dying or dead of the spirochetal disease.The findings presented in this note suggest that gophers, or similar wild rodents, might act in nature as hosts for Leptospira icterohemorrhagiœ.

Effects of the Introduction of Blood from Bred Rabbits upon Immature Rabbits.

ConclusionsSome evidence was obtained supporting the theory that ovulation in the rabbit occurs as a result of an increased production of anterior lobe hormone.

THE PHENOMENA CONCERNED WITH "REACTIONS" FOLLOWING THE TRANSFUSION OF BLOOD

Clinically, it is recognized that the intravascular introduction of blood to a subject from an individual of homologous species is a therapeutic procedure of first rank. At times, blood transfusion may be the only agency through which life may be saved or prolonged. While differences of opinion exist as to the method of choice in transfusion, there is unanimous agreement that the factor of greatest importance, with respect to the results, is the blood itself. In this viable fluid tissue lie the potentialities for clinical betterment or for harm. Numerous contributions have emphasized the benefits that have followed blood transfusion.1The harmful consequences of the procedure have been dwelt on indifferently by clinicians and in incomplete or detached fashion by laboratory workers. Our report is an attempt to describe (a) the type of unwished-for events that may follow blood transfusion and to discuss the nature of such phenomena, and

INTRAPERITONEAL TRANSFUSION WITH CITRATED BLOOD

The difficulties encountered in the transfusion of blood in infancy and early childhood have prompted numerous investigators to attempt other simpler procedures. Consequently, the use of blood in infants and children has been confined until recently to (1) subcutaneous or intramuscular injection of blood; (2) the introduction of blood into one of the larger peripheral veins, and (3) transfusion into the superior longitudinal sinus. The subcutaneous or intramuscular injection of blood, which is now used chiefly in the treatment of hemorrhagic disease of the new-born, was at one time considered effective in conditions in which a transfusion was indicated. That this method is not in a strict sense a blood transfusion is substantiated by Taylor, 1 who found that only a small number of the cells so injected ever reach the circulation. Transfusion by the use of one of the larger peripheral veins has been attended in many cases with