Intraosseous Cavernous Hemangioma Research Articles

Cavernous hemangioma of the skull and meningioma: association or coincidence?

Intraosseous cavernous hemangiomas of the skull are rare. Meningiomas are quite frequently encountered in a neurosurgical practice. The association between these two entities is nevertheless very uncommon. The authors present a case of a 72-year-old woman suffering from headache. The MRI showed a parietal meningioma with adjacent thick bone. The meningioma and the bone were removed. The histological examination confirmed the diagnosis of meningioma and revealed a cavernoma of the skull. The relationship between the lesions suggests more than a coincidental association. Several hypotheses are proposed to explain common causal connections.

A case of primary intraosseous cavernous hemangioma extending from the orbital rim to the sphenoid wing: a case report

A primary intraosseous cavernous hemangioma located at the sphenoid bone with extensive involvement of the orbital roof and the lateral wall of the orbit is very rare. A 48-year-old woman presented with progressive right exophthalmos and diplopia. CT showed a bony mass lesion in the right sphenoid bone extending to the orbital bone. MRI showed an abnormal lesion in the sphenoid bone, which was heterogeneously enhanced with gadolinium. All of the abnormal bone was surgically removed, and histological examination confirmed a cavernous angioma. We also present a brief clinical and radiological review of seven previously reported cases.

Multiple cavernous hemangiomas of the skull with dural tail sign: a case report and literature review

BackgroundPrimary intraosseous cavernous hemangioma is a rare bony tumor. To date, only 9 cases of multiple lesions and 2 cases with a dural tail sign have been reported.Case presentationHere, we present a case of multiple cavernous hemangiomas of the skull with dural tail sign in a 24-year-old man. No abnormalities were observed in the right orbit by craniography, but frontal bone destruction was unintentionally discovered. Computed tomography and magnetic resonance imaging demonstrated multiple intraosseous lesions that destroyed the surrounding bone and intracranial extension. Total resection of the two lesions and cranioplasty were performed. Histological examination confirmed the lesions as a cavernous hemangioma.ConclusionCavernous hemangioma is a rare bony tumor that should be considered in the differential diagnosis of skull tumors. Resection of all lesions should be performed on patients with multiple cavernous hemangiomas, and these patients should have regular follow-up examinations. Based on this case, and our literature review, we found that outcomes are usually very good.

Intraosseous hemangioma arising in the clavicle

Intraosseous hemangioma (IH) is commonly seen in the vertebral column and skull: however, IH occurring in the appendicular skeleton, including the clavicle, is uncommon. We herein report the case of a 69-year-old female presenting with IH of the left clavicle. The findings of preoperative imaging studies, including radiographs, computed tomography (CT), magnetic resonance imaging, fluorine-18-fludeoxyglucose ((18)F-FDG) positron emission tomography (PET)/CT and ultrasonography, are described. In particular, (18)F-FDG PET/CT showed an ill-defined osteolytic lesion with abnormally high FDG uptake. Surgical en bloc resection with preoperative embolization was carried out and a histopathological examination confirmed the presence of an intraosseous cavernous hemangioma in the clavicle.

Primary Intraosseous Cavernous Hemangioma of the Clivus: Case Report and Review of the Literature

Primary intraosseous hemangiomas are benign, vascular malformations that account for approximately 1% of all primary bone neoplasms. These tumors are mostly found in vertebral bodies and are rarely seen in the calvarium, where they represent 0.2% of bony neoplasms. When found in the skull, they tend to present with vague symptoms and do not have the typical radiological findings suggestive of hemangiomas. Because of this, these tumors can be missed in many cases or may be misinterpreted as more ominous lesions like multiple myeloma or osteosarcoma. Involvement of the skull base is exceedingly rare, and presentation with cranial nerve unilateral polyneuropathies has not been reported. We report a patient case with review of recent pertinent literature.

Primary Intraosseous Hemangioma in the Frontal Bone

Primary Intraosseous Hemangioma in the Frontal Bone

Posttraumatic skull hemangioma

Intraosseous cavernous hemangiomas of the skull are rare lesions for which the origin is unclear. The authors present a case in which there was a radiologically documented history of trauma preceding the development of a hemangioma in the frontal bone. In a review of the literature the authors found 83 cases of skull hemangiomas, and 43% of the lesions were located in the frontal bone. In 25% of these lesions, previous trauma was reported anamnestically. The present case and radiological findings related to it suggest a causal relationship between trauma and the development of intraosseous hemangioma.

Primary Intraosseous Cavernous hemangioma of the Zygoma: A Case Report and Literature Review

Intraosseous hemangiomas are rare. We report the case of a 47-year-old man who presented with a gradually enlarging left zygomatic mass that had caused pain, deformity, and superficial soft-tissue swelling. Computed tomography revealed a well-circumscribed 2.0 × 2.5-cm mass with a ground-glass matrix in the left zygoma. Following surgical excision, the patient's symptoms resolved. Findings on pathologic examination of the excised tissue were consistent with an intraosseous cavernous hemangioma. We describe the features of this rare case, we discuss the pertinent radiologic features and pathophysiology of intraosseous hemangiomas, and we review the available literature.

A Case of Intraosseous Cavernous Hemangioma of the Maxillary Bone

Intraosseous hemangiomas are rare, comprising only 0.5% to 1% of all osseous neoplasms. The most common locations are the vertebral column and the skull bones; nevertheless, the maxillary bone is quite a rare location and only a few cases have been described in the literature thus far. We describe a case of a 48-year-old woman who was referred to our hospital with a suspected maxillary tumor incidentally discovered on (18) F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging performed during a general medical examination. Computed tomography (CT) demonstrated a 3 cm bony tumor with a honeycomb appearance occupying the left maxillary sinus. Complete surgical resection via the Caldwell-Luc procedure was performed for the purpose of diagnosis and treatment. Histological examination revealed that the tumor was an intraosseous cavernous hemangioma originating from the maxillary bone. Although preoperative angiography and embolization were not performed, intraoperative-blood loss was minimal. No recurrence has been seen in a follow-up period of 3 years.

Primary calvarial hemagioma presenting as chronic subdural hematoma

Primary intra-osseous cavernous hemangiomas (PICHs) represent slow-growing benign vascular malformations, most frequently found in parietal and frontal bones and account for ~0.2% of all bone tumors and 10% of benign skull tumors. We report a case of 70-year-old gentleman presented with progressive headache involving left frontal region, aggravated on coughing of five months duration. Radiological features were suggestive of left frontal calvarial lesion and left fronto-parietal chronic subdural hematoma. Histopathology of the calvarial lesion was suggestive of cavernous hemangioma. Meticulous radiological and clinical investigation is essential to rule out all other possible lesions; histopathology confirms the diagnoses, and the preferred treatment is complete tumor removal and management of the associated lesions (i.e., chronic subdural hematoma in present case).

Primary intraosseous cavernous hemangioma of the toe

Intraosseous cavernous hemangioma is an uncommon benign vascular tumor. A 21-year-old man presented with a small painless swelling of the left foot's long toe. X-ray examination showed an outgrowing bony lesion that has cortical continuity in the tip of the long toe's distal phalanx lateral aspect. Preoperative examination yielded no final diagnosis. En bloc resection was performed. The histological diagnosis was intraosseous cavernous hemangioma. To the best of our knowledge, this case is a first report of primary intraosseous cavernous hemangioma of the toe.

Giant primary ossified cavernous hemangioma of the skull in an adult: A rare calvarial tumor

Primary intraosseous cavernous hemangiomas (PICHs) of the cranium are rare benign vascular tumors that account for about 0.2 % of all bone tumors and 10 % of benign skull tumors. They generally present as osteolytic lesions with honeycomb pattern of calcification. Completely ossified cavernous hemangioma of the calvarium in an adult has not been reported previously. A 28-year-old female presented to us with a large right parietal skull mass that had been present since the last 15 years. Total resection of the lesion was performed. Pathological examination was suggestive of cavernous hemangioma of the skull bone. Cavernous hemangioma should be considered as one of the differential diagnosis in any case of bony swelling of the calvarium so that adequate preoperative planning can be made to minimize blood loss and subsequent morbidity.

Intraosseous cavernous hemangioma of the middle turbinate

Hemangiomas mostly arise from the soft tissues, and intraosseous hemangiomas are uncommon. They usually occur in the vertebra and skull bones, and intraosseous hemangioma of the nasal cavity is exceedingly rare. We describe a 56-year-old woman who was referred to our hospital with a tumor in her right nasal cavity, without subjective symptoms such as epistaxis. The tumor was located at the front end of the right middle turbinate. Enhanced computed tomography demonstrated a 3 cm×2cm expansive bony tumor replacing the bottom of the right middle turbinate with some partial enhancement effects. The characteristic honeycomb appearance was observed. The tumor and right middle turbinate were excised en bloc by the endoscopic endonasal approach. No complications or severe bleeding occurred during the peri-operative period. Histological examination showed endothelium-lined blood-filled vascular spaces within the bony trabeculae, which suggested the typical pattern of intraosseous cavernous hemangioma. To the best of our knowledge, this is the first case report of intraosseous cavernous hemangioma of the middle turbinate in the English literature.

Unusual lesion of the clivus: diagnosis and discussion

DiagnosisBased on the imaging findings, the diagnosis of a primaryintraosseous cavernous hemangioma of the clivus was made,whichwasconfirmedafterbiopsyandsurgicalremovalofthelesion.DiscussionPrimary intraosseous cavernous hemangiomas (PICHs) ofthe skull are rare benign tumors that account for about 0.2–1% of all benign neoplasms of [1, 2]. They are typicallylocated in the parietal and frontal bones of the calvarium,whereas location in the craniofacial bones is less common(zygoma, maxilla, mandible, and vomer) [1, 2]. PICHs ofthe skull base and the clivus are extremely rare [1, 2].PICHs are usually solitary and most commonly occur inwomen in the second through fifth decades [1, 2].Histologically, hemangiomas are classified as cavernousand capillary hemangiomas [2]. Cavernous hemangiomasare composed of large dilated blood vessels separated byfibrous tissue, whereas capillary hemangiomas lack fibroussepta and have smaller vascular lumens. Calvarial heman-giomas are usually of the cavernous type, whereas vertebralhemangiomas are most frequently of the capillary type [3].The lesion is often discovered as an incidental finding onCT or MRI scan of the brain done for other reasons. Othersymptomsincludepainandvisibleorpalpablebonyhardmassof the calvarium or neurologic deficits in case of intracranialexpansion.Somepatientspresentwithperiodicdullheadachesthat may increase as the hemangioma expands [1].CT scan shows an intraosseous mass with a honeycombor sunburst pattern, very similar to a vertebral hemangioma.Expansion of the cortical bone may occur, but theperiosteum remains intact [1, 2]. Fatty tissue may be seenbetween the thickened trabeculae.The signal intensity on MRI is variable, depending on thequantity ofslow-moving venousblood and onthe ratio of redmarrow to converted marrow present within the lesion [1, 2].Lesions with a high fatty content are of high signal intensityon T1-weighted images (WI), such as in our case. Largerlesions tend to have a low signal intensity on T1-WI [1]. OnT2-WI, a high signal intensity may be caused by pooling ofblood or slow-flowing blood. Correlation between MRappearance on T1- and T2-weighted images and histologicalfindings from autopsy specimens has only been performed instudies with a limited number of patients [4]. Cavernoushemangiomas typically enhance after administration ofgadolinium contrast [1, 2].CT scan is more helpful than MRI in planning surgerybecause the extent of the lesion is better evaluated on bonewindows [5]. PICHs of the clivus may mimic other morecommon tumors of the skull base, particularly when theclassic imaging features are absent [2].

Intraosseous Hemangioma of the Inferior Turbinate

The nasal cavity harbors an enormous variety of neoplasms, including epithelial and mesenchymal tumors. Hemangioma is an infrequent mesenchymal tumor of the nasal cavity, mostly arising in the mucosa and rarely in the bones. We describe the case of a 73-year-old woman who was referred to our hospital with a tumor in her left nasal cavity. The tumor originated from the left inferior turbinate. Histological examination subsequent to complete excision revealed that the tumor was an intraosseous cavernous hemangioma. To our knowledge, this is the second case of intraosseous hemangioma of the inferior turbinate reported in the English literature.

Hemangioma cavernoso multifocal en cráneo. Revisión de un caso

A 39 year old female presented with a multifocal lesions in the skull, at the frontal right and parietal left. We performed bilateral craniectomies guided with navigation, and the bone defects were repaired with titanium mesh. The pathological examination reported intraosseous cavernous hemangioma in both lesions. Follow up of six months without any complication or recurrence and good cosmetic outcome.

Multiples hémangiomes caverneux de la voûte du crâne

Intraosseous cavernous hemangioma is rarely located in the calvarium. This benign tumor, arising from the intrinsic vasculature of bone, grows slowly over a period of years before it causes symptoms such as headaches or localized compression. We report here the case of a 27-year-old man, who presented with multiple calvarial cavernous hemangiomas associated with several hepatic hemangiomas. The patient had a family history of the disease, and is only the second case of multiple calvarial cavernous hemangiomas reported in the literature. The clinical, radiological and therapeutic aspects of this rare entity are also discussed.

Cavernous hemangioma of the skull: 3 case reports

Background Intraosseous cavernous hemangiomas of the bone are uncommon tumors, accounting for 0.7% to 1% of all bone neoplasms. The vertebral column is most often affected, followed by the skull. Calvarial cavernous hemangioma is rare, comprising about 0.2% of all benign neoplasms of the skull. Cases Reports We describe 3 patients with calvarial hemangiomas that were localized frontally (2 cases) and parietally. The diameter ranged from 2 to 3 cm. They presented with slowly growing mass, hard to pressure, with freely mobile skin above the cavernoma sites. Cranial CT scan showed osteolytic lesion with erosion of the tabula externa. Magnetic resonance imaging performed in one patient showed hypointense lesion on T1-weighted image and hyperintense on T2-weighted image. Resection and postoperative course were uneventful. Pathological examination revealed a cavernous hemangioma of the diploe. Conclusion Skull cavernous hemangiomas are rare benign tumors. The preferred treatment is complete tumor removal with normal bony margins. Sometimes, the classic radiographic appearances are not evident. Consequently, the diagnosis is most often made during surgical resection.

Resection of an Orbital Rim Intraosseous Cavernous Hemangioma and Reconstruction by Chin Graft and Resorbable Fixation Plate

Intraosseous hemangiomas are uncommon in the orbital rim and pose difficulties for removal and reconstruction. Here we report an excellent cosmetic and functional outcome following en bloc resection and reconstruction, using a corticocancellous bone graft from the chin and LactoSorb perforated tray plate. The lesion treated is characterized by both computed axial tomography and histology, while the postsurgical bony contour also is revealed by CT.

De novo development of intraosseous cavernous hemangioma

Intraosseous cavernous hemangiomas are rare and not often multifocal. De novo development of a skull cavernous hemangioma has not been described previously. We present a 20-year-old man who was operated upon for a skull cavernoma in the right frontal area and developed a new lesion 3 years later in the right occipital region. The first lesion was removed completely and the postoperative course was uneventful. Histology showed an intraosseous cavernous hemangioma. MRI follow-up revealed a new lesion in the right occipital region. At the time of the first operation this lesion was not seen on CT or MRI scan. Surgical removal was performed and histology again showed a cavernous hemangioma. The patient seems to be unique and it is important to keep young patients with the diagnosis of cavernous hemangioma under close follow-up. This supports the experience from parenchymatous cavernous hemangiomas that this malformation may become a dynamic disease.