Abstract Aim-Background: Hirschsprung Disease (HD), congenital intestinal aganglionosis, or aganglionic megacolon rep-resents a congenital abnormality which is characterized by the absence of neural crest-derived enteric neural ganglia along a variable length of the intestine. Affecting mainly children, it is an infrequent clinical entity in adulthood. Case report: The case of a 23-year-old female with an acute faecal impaction and history of chronic constipation and long-term use of laxatives is presented. An alternative surgical technique (curvilinear stapler) for coloanal anastomosis and review of the literature are discussed. Results: A successful U-shaped anastomosis 1.5-2 cm above the dentate line, with no postoperative stricture or incontinence as assessed by manometry is described below in this case report. Conclusion: Proctocolectomy by curvilinear staplers represents an efficacious treatment method for aganglionosis, offering a good quality of life to patients with Hirschsprung.