Abstract The incidence of cancer in the world population in 2002 was estimated at 11 million new cases, in 2020 this estimate is approximately 20 million. Cancer is a global public health problem. Testicular cancer (TC) mainly affects men aged 15 to 40 years, and the incidence is about 5/100,000. Typically, tumors are aggressive and cause a great psychological impact on patients. Penile cancer (PC) represents 2% of all types of tumors that affect men in Brazil. The majority of the affected population are elderly men. Normally the tumor is identified at an advanced stage, when the only available treatment is total or partial penectomy, causing great emotional impact. This work aims to evaluate the impact of psychotherapy, in an open group, on the Quality of Life Related to Health and Sexuality in patients with CT and CP who have been diagnosed, are undergoing treatment or are being monitored after treatment. Data are collected through an initial interview (Identification, Anamnesis, Health Anamnesis, Degree of Satisfaction with Life and Sexuality, Affective-Emotional Assessment and Treatment Data), SF-36 questionnaire and IIEF-5 short form, in patients who were diagnosed, underwent treatment or are being monitored at the outpatient clinic, and reapplied at the end of 12 sessions. At each session, 5 questions are answered regarding the perception of the previous session. The group is available once a week for 12 weeks. Sessions last 90 minutes, led by the same psychologist. The research is being developed considering the ethical principles of secrecy, privacy and confidentiality. At the beginning of the process, the Free and Informed Consent Form is delivered as well as details regarding the research. It is also explained that participation is voluntary and that the participant may leave the research at any time, without this affecting their treatment and follow-up. Financing No conflict.