The implementation of roadside air purifiers has emerged as an effective active control measure to alleviate air pollution in urban street canyons. However, technical questions raised under real conditions remain challenging. In this study, we conducted a pilot-scale investigation involving seven units of self-designed roadside air purifiers in an urban street canyon in Hong Kong. The air cleaning effects were quantified with an air quality sensor network after rigorous quality control. The removal efficiencies of Nitrogen dioxide (NO2), Fine suspended particulates (PM2.5), Carbon monoxide (CO), and Nitric oxide (NO) were determined by comparing with simultaneously measured ambient concentrations, with hourly average efficiencies of 14.0 %–16.9 %, 3.5–10.0 %, 11.9 %–18.7 %, and 19.2 %–44.9 %, respectively. Generally, the purification effects presented variations depending on the ambient pollutants' levels. Higher ambient concentrations of NO2, PM2.5, CO correlated with increased purification effects, while NO presented the opposite trend. The influence of interval distance combined with spatial distribution indicated the operation of purifiers will induce local NO2 attenuation even at an interval distance of four meters. Statistical analysis delivered evidence the air cleaning ability exhibited optimal performance when relative humidity level is ranged from 70 % to 90 %, aligning with the prevailing conditions in Hong Kong. Additionally, improved purification effects were observed at the downwind direction, and their performance was enhanced when the wind speed exceeded 2.5 m/s. Moreover, we estimated the operational lifetime of the air purifiers to be approximately 130 days, offering crucial information regarding the filter replacement cycle. This work serves as a pioneering case study, showcasing the feasibility and deployment considerations of roadside air purifiers in effectively controlling air pollution in urban environments.