The genus Meristotheca (Solieriaceae) includes fifteen currently accepted species. They are widely distributed throughout the tropics and subtropics of both hemispheres, inhabiting the intertidal and subtidal regions of rocky shores. Molecular phylogenetic studies allowed a precise understanding of the species diversity and biogeography of the genus. The commercial value of certain species of Meristotheca lies in its use primarily as food for direct human consumption and to some extent as raw materials for extraction of carrageenan and other bioactive compounds. Intensified harvesting of the seaweeds resulted in the depletion of their natural beds; hence, several attempts have been made for mariculture. The management effort for the farming of Meristotheca on a commercial scale is still at its early stage. Studies on the phenology, sporulation, callus induction and thallus regeneration, photosynthesis, and growth of these potentially useful species contributed to the advancement of cultivation technologies. Further research on the biochemistry and utilization of Meristotheca species is necessary for the commercial competitiveness of these promising seaweed resources.