Deep learning models have been used to improve seismic trace interpolation in recent years. Encode-Decode models, such as U-Net, have been implemented to solve interpolation problems. The success of U-Net in seismic interpolation has inspired us to test the U-net also as an image generator for further Generative Adversarial Network (GAN) interpolation models. The objective of the present paper is to compare the performance of U-Net inside the GAN models for seismic interpolation: the U-Net alone and two GAN models, the conditional GAN (cGAN) and the Cycle Consistent GAN (CycleGAN), both using the U-Net as a generator inside their workflow. We test the methodologies for two scenarios: regular and irregular interpolation. All tests were performed in a real dataset from the Tupi Field which belongs to the Brazilian pre-salt region. A comparison of the statistical metrics shows that cGAN performs better than CycleGAN and the U-Net alone in most cases. The computational training time of the cGAN model, for all interpolation scenarios, is better than the CycleGAN. Finally, the cGAN training time is comparable to the training of the U-Net alone.