Interpersonal Transmission Research Articles

Man Creates Culture, Culture Creates Man: The Reciprocal Relationship Between Humanity and Culture in the Life and Thought of Saint John Paul II

The life and thought of Karol Wojtyła/John Paul II embody and elaborate the reciprocal relationship between humanity and culture. As historian and custodian of faith and culture, John Paul II provided a conceptual understanding of the mutually formative influences of person and community. Polish faith and culture were the cradle and crucible that formed Wojtyła. In return, Wojtyła bestowed a legacy of liberty to Polish faith and culture. As prophet and pastor of faith and culture, John Paul II continues to challenge humanity to faithful personal formation and interpersonal transmission of this heritage for the sake of future generations.

Spontaneous movement synchrony as an exogenous source for interbrain synchronization in cooperative learning.

Learning through cooperation with conspecifics-'cooperative learning'-is critical to cultural evolution and survival. Recent progress has established that interbrain synchronization (IBS) between individuals predicts success in cooperative learning. However, the likely sources of IBS during learning interactions remain poorly understood. To address this dearth of knowledge, we tested whether movement synchrony serves as an exogenous factor that drives IBS, taking an embodiment perspective. We formed dyads of individuals with varying levels of prior knowledge (high-high (HH), high-low (HL), low-low (LL) dyads) and instructed them to collaboratively analyse an ancient Chinese poem. During the task, we simultaneously recorded their brain activity using functional near-infrared spectroscopy and filmed the entire experiment to parse interpersonal movement synchrony using the computer-vision motion energy analysis. Interestingly, the homogeneous groups (HH and/or LL) exhibited stronger movement synchrony and IBS compared with the heterogeneous group. Importantly, mediation analysis revealed that spontaneous and synchronized body movements between individuals contribute to IBS, hence facilitating learning. This study therefore fills a critical gap in our understanding of how interpersonal transmission of information between individual brains, associated with behavioural entrainment, shapes social learning. This article is part of the theme issue 'Minds in movement: embodied cognition in the age of artificial intelligence'.

Optimal control analysis on the spread of COVID-19: Impact of contact transmission and environmental contamination

The study investigates the intricate dynamics of SARS-CoV-2 transmission, with a particular focus on both close-contact interactions and environmental factors. Using advanced mathematical modeling and epidemiological analysis, explored the effects of these transmission pathways on the spread of COVID-19. The equilibrium points for both the disease-free and endemic states calculated and evaluated their global stability. Additionally, the basic reproduction number (R0) is derived to quantify the transmission potential of the virus.To ensure model accuracy, numerical simulations are performed using MATLAB, utilizing daily COVID-19 case data from India. Parameter values are sourced from existing literature, with certain parameters estimated through fitting the model to observed data. Crucially, the model incorporates environmental transmission factors, such as surface contamination and airborne spread. The inclusion of these factors provides a more comprehensive understanding of the virus’s spread, demonstrating the importance of interventions like use of face masks, environmental sanitization, vaccine efficacy, availability of treatment resources underappreciated when focusing solely on direct human contact. A sensitivity analysis is conducted to assess the impact of different parameters on R0, with results visualized through heat maps to identify the most influential factors.Furthermore, Pontryagin’s maximum principle is employed to develop an optimal control model, enabling the formulation of effective intervention strategies. By analysing both interpersonal and environmental transmission mechanisms, this study offers a more holistic framework for understanding SARS-CoV-2 transmission. The insights gained are critical for informing public health strategies, emphasizing the necessity of addressing both direct contact and environmental sources of infection to more effectively manage current and future outbreaks.

Visualization and Quantification of Facemask Leakage Flows and Interpersonal Transmission with Varying Face Coverings

Although mask-wearing is now widespread, the knowledge of how to quantify or improve their performance remains surprisingly limited and is largely based on empirical evidence. The objective of this study was to visualize the expiratory airflows from facemasks and evaluate aerosol transmission between two persons. Different visualization methods were explored, including the Schlieren optical system, laser/LED-particle imaging system, thermal camera, and vapor–SarGel system. The leakage flows and escaped aerosols were quantified using a hotwire anemometer and a particle counter, respectively. The results show that mask-wearing reduces the exhaled flow velocity from 2~4 m/s (with no facemask) to around 0.1 m/s, thus decreasing droplet transmission speeds. Cloth, surgical, and KN95 masks showed varying leakage flows at the nose top, sides, and chin. The leakage rate also differed between inhalation and exhalation. The neck gaiter has low filtration efficiency and high leakage fractions, providing low protection efficiency. There was considerable deposition in the mouth–nose area, as well as the neck, chin, and jaw, which heightened the risk of self-inoculation through spontaneous face-touching. A face shield plus surgical mask greatly reduced droplets on the head, neck, and face, indicating that double face coverings can be highly effective when a single mask is insufficient. The vapor–SarGel system provided a practical approach to study interpersonal transmission under varying close contact scenarios or with different face coverings.

How new rural elites facilitate community-based homestead system reform in rural China: A perspective of village transformation

In line with China's rural transformation, the homestead system reform (HSR) pilots have been launched to rectify adverse land-related issues by formalising and capitalising land property rights. In contrast with a government-led model prevalent among most national HSR pilots, a community-based approach has been experimented with and proven efficient in Yujiang County, southern China. It highlights a pivotal role of the endogenous and public-spirited activists who are locally called ‘new rural elites’ (NREs). From the perspective of village transformation processes, this paper establishes a theoretical framework and employs a case study in Yujiang to interpret the underlying rationale for NREs' involvement in HSR. The findings indicate that HSR, aiming at multi-level space reshaping and ‘three rights separation’ reform, is in alignment with the triple processes of village transformation (i.e., systemic, communal, and living). The NREs represent a cultural force for facilitating village transformation, which is underpinned by the capacity, channel and carrier endowed by urban-rural linkages, interpersonal value transmission and community social solidarity, respectively. The benevolent dominance of the NREs is jointly shaped by governmental empowerment and accountability, egalitarian property rights design and strong social solidarity. To expand NREs' benevolent roles, this study recommends aligning community empowerment with the improvements of community-based action capacity.

Cumulative violence exposures among men who have sex with men living with HIV in India: Psychosocial correlates of HIV care continuum outcomes.

Lifetime exposures to violence among men who have sex with men (MSM) are associated with multiple psychosocial health risks and can affect engagement and outcomes of HIV treatment. This study a) explored relationships between levels of exposures to violence and HIV care continuum outcomes among MSM living with HIV in India, and b) identified psychosocial correlates of HIV care continuum outcomes among MSM living with HIV and those with lifetime cumulative exposures to violence (CVE). CVE referred to exposures to violence in both childhood and adulthood. This cross-sectional analysis used survey data collected between August 2016 and May 2017 from 1763 men who have sex with men living with HIV across 10 cities in India, using respondent-driven sampling. We found that higher levels of violence exposure were significantly associated with lower awareness of HIV positive status, and lower likelihood of initiating antiretroviral therapy. Compared with MSM living with HIV that had no CVE, those with CVE were more likely to report perpetration of interpersonal violence, alcohol misuse, depressive symptoms, and HIV transmission risk behaviors and to have two to four co-occurring psychosocial problems. In multivariable analysis with the subset of MSM with CVE, psychosocial correlates significantly associated with at least one HIV care continuum outcome were HIV transmission risk behaviors, perpetration of interpersonal violence, depression, and alcohol misuse. The findings highlight the need for integrating care for lifetime violence exposures and associated behavioral problems in HIV care settings for men who have sex with men living with HIV in India.

Impact of social distancing on disease transmission risk in the context of a pandemic.

Changes in pedestrian dynamics caused by social distancing policies place new demands on pedestrian motion modeling during the pandemic. This study summarizes pedestrian movement characteristics during the pandemic, based on which, the traditional floor-field cellular automata model was improved by introducing two floor fields related to pedestrian density to simulate social distancing in crowded places. Especially, the cumulative density field guides pedestrians in route selection, thereby compensating for the limitation of the previous models in which only local repulsion was considered. By selecting an appropriate combination of parameters, the desired social distancing behavior can be observed. Then, the rationality of our model is verified by the fundamental diagram. Moreover, to assess the influences of social distancing on the risk of disease transmission, we considered both person-person transmission and environment-person transmission. The simulation results show that although social distancing is effective in preventing interpersonal transmission, an increase in environmental transmission may somewhat offset this effect. We also examined the influence of individual motion heterogeneity on infection spread and found that the containment was the best when only patients complied with the social distancing restriction. The trade-off between safety and efficiency associated with social distancing was also initially explored in this study.

The development of digital model of college Civics teaching combined with information diffusion model

Abstract In this paper, the information sphere radiation model describes the diffusion process of information in cyberspace. In real space, the information ring radiation model represents how information diffuses through interpersonal transmission in social circles. Secondly, the degree distribution of nodes in the network is described by the spatial topology’s degree distribution function and how information diffusion in the network is constructed. Finally, the model’s effectiveness is verified through the simulation of the total number of nodes function Q(t) for the diffusion of information in Civic and Political Science teaching. The mean diffusion degree is around 1.2 according to the results when teachers and students are the main interactors. In the case of student-content interaction and hybrid interaction, the mean value of diffusion is around 2.3. In the exercise session, however, the student-student diffusion degree reached 3. Through the information diffusion model, this paper facilitates the development of a digital model for college Civics teaching.

Do your friends stress you out? A field study of the spread of stress through a community network.

In this study, we seek to understand how stress changes in dynamic social systems. Where prior work on the interpersonal transmission of stress focused on pairs of individuals and small groups, we adopt a network perspective to investigate how the distribution of stress in an individual's social environment influences their stress appraisal process. We conducted a 6-month longitudinal study of 315 early to midcareer adults in professional master's programs as they encountered the stress of everyday academic life. We follow the dynamics of the participants' networks and their concomitant stress at four key time points during those 6 months. We find that the perceived stress of one's social contacts affects their experience of stress in this setting. Yet, not everyone is equally susceptible to this social influence. In particular, we find that social influence is substantially amplified under conditions of relative consensus among one's social contacts. Also, a low level of neuroticism, a high level of conscientiousness, and a high level of internal control orientation help buffer the transmission of stress. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Animal experiments on respiratory viruses and analogous studies of infection factors for interpersonal transmission.

Air pollution caused by SARS-CoV-2 and other viruses in human settlements will have a great impact on human health, but also a great risk of transmission. The transmission power of the virus can be represented by quanta number in the Wells-Riley model. In order to solve the problem of different dynamic transmission scenarios, only a single influencing factor is considered when predicting the infection rate, which leads to large differences in quanta calculated in the same space. In this paper, an analog model is established to define the indoor air cleaning index RL and the space ratio parameter. Based on infection data analysis and rule summary in animal experiments, factors affecting quanta in interpersonal communication were explored. Finally, by analogy, the factors affecting person-to-person transmission mainly include viral load of infected person, distance between individuals, etc., the more severe the symptoms, the closer the number of days of illness to the peak, and the closer the distance to the quanta. In summary, there are many factors that affect the infection rate of susceptible people in the human settlement environment. This study provides reference indicators for environmental governance under the COVID-19 epidemic, provides reference opinions for healthy interpersonal communication and human behavior, and provides some reference for accurately judging the trend of epidemic spread and responding to the epidemic.

Upper Aerodigestive Tract Procedures in COVID-19 Pandemic

Since the late 2019 months’ pandemic of Corona Virus Disease-2019 (COVID-19), it has spread globally and claimed abundant lives due to its expeditious interpersonal transmission and high mortality rate. Early studies showed that the upper aerodigestive tract procedures had the highest rates of nosocomial spread due to high viral load in upper respiratory and pharyngeal secretions. Between March 10 and April 10, 2020, a total of 28 rigid endoscopies were performed under general anesthesia for the removal of esophageal foreign bodies at our center. All the patients were screened on admission for symptoms of COVID-19 and a chest CT scan was performed and they were later followed up for further investigations. No patient had symptoms of COVID-19 (fever, cough, and dyspnea) on admission, and only one patient (3.57 %) had a suspicious CT scan for COVID-19. The mean age of 27 asymptomatic cases, including 14 men and 13 women, was 45.2 years old. Their average hospital stay was 0.8 days. all patients were later interviewed, inspected, and closely observed for any upcoming symptoms which would raise suspicion for COVID-19 during isolation. Of the 27 patients who cooperated, none showed COVID-19 symptoms. What makes this experiment prominent is that with suitable plans in a careful and precautionary manner, we can provide first-rate care for patients and meanwhile protect physicians during this pandemic promptly.

Interpersonal transmission of ROCD symptoms and susceptibility to infidelity in romantic relationships

Relationship obsessive–compulsive disorder (ROCD) is a disabling presentation of obsessive-compulsive disorder (OCD) centering on close interpersonal relationships. Previous studies focused on the personal consequences of ROCD symptoms. Yet, studies investigating the consequences of ROCD symptoms on one's partner are scarce. In this study, we assessed whether exposure to romantic partners' elevated ROCD symptoms would heighten participants' ROCD symptoms and would increase participants' evaluation of their own and their partners' susceptibility to infidelity. Heterosexual couples (Ncouples = 50; Mage = 25.8) completed self-report questionnaires. One randomly selected partner of each romantic dyad was then randomly allocated to being exposed to information suggesting their partner has low (low-exposure) or high (high-exposure) levels of ROCD symptoms. Results indicated that participants in the high-exposure group showed higher ROCD symptoms than participants in the low-exposure group. Exposure to allegedly elevated levels of partners' ROCD symptoms also led participants to evaluate their own and their partners' susceptibility to infidelity as higher than participants in the low-exposure group, particularly among participants with pre-existing ROCD symptoms. These results illustrate a ‘contagious’ effect of unmediated exposure to partners' ROCD symptoms and its potentially unfavorable consequences. Clinical implications regarding partner involvement in the treatment of ROCD are discussed.

Kaposi's Sarcoma-Associated Herpesvirus Immediate Early Proteins Trigger FOXQ1 Expression in Oral Epithelial Cells, Engaging in a Novel Lytic Cycle-Sustaining Positive Feedback Loop.

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus that can replicate in oral epithelial cells to promote viral transmission via saliva. To identify novel regulators of KSHV oral infection, we performed a transcriptome analysis of KSHV-infected primary human gingival epithelial (HGEP) cells, which identified the gene coding for the host transcription factor FOXQ1 as the top induced host gene. FOXQ1 is nearly undetectable in uninfected HGEP and telomerase-immortalized gingival keratinocytes (TIGK) cells but is highly expressed within hours of KSHV infection. We found that while the FOXQ1 promoter lacks activating histone acetylation marks in uninfected oral epithelial cells, these marks accumulate in the FOXQ1 promoter in infected cells, revealing a rapid epigenetic reprogramming event. To evaluate FOXQ1 function, we depleted FOXQ1 in KSHV-infected TIGK cells, which resulted in reduced accumulation of KSHV lytic proteins and viral DNA over the course of 4 days of infection, uncovering a novel lytic cycle-sustaining role of FOXQ1. A screen of KSHV lytic proteins demonstrated that the immediate early proteins ORF45 and replication and transcription activator (RTA) were both sufficient for FOXQ1 induction in oral epithelial cells, indicating active involvement of incoming and rapidly expressed factors in altering host gene expression. ORF45 is known to sustain extracellular signal-regulated kinase (ERK) p90 ribosomal s6 kinase (RSK) pathway activity to promote lytic infection. We found that an ORF45 mutant lacking RSK activation function failed to induce FOXQ1 in TIGK cells, revealing that ORF45 uses a shared mechanism to rapidly induce both host and viral genes to sustain lytic infection in oral epithelial cells. IMPORTANCE The oral cavity is a primary site of initial contact and entry for many viruses. Viral replication in the oral epithelium promotes viral shedding in saliva, allowing interpersonal transmission, as well as spread to other cell types, where chronic infection can be established. Understanding the regulation of KSHV infection in the oral epithelium would allow for the design of universal strategies to target the first stage of viral infection, thereby halting systemic viral pathogenesis. Overall, we uncover a novel positive feedback loop in which immediate early KSHV factors drive rapid host reprogramming of oral epithelial cells to sustain the lytic cycle in the oral cavity.

Modeling the effect of health education and individual participation on the increase of sports population and optimal design.

Health education plays an important role in cultivating people's awareness of participating in physical exercise. In this paper, a new differential equation model is established to dynamically demonstrate the different impact of mass communication and interpersonal communication in health education on people's participation in physical exercise. Theoretical analysis shows that health education does not affect the system threshold, but individual participation does. The combination of the two leads to different equilibria and affects the stability of equilibria. When mass communication, interpersonal communication and individual participation satisfy different conditions, the system will obtain different positive equilibrium with different number of sports population. If the interpersonal transmission rate of information is bigger, there is a positive equilibrium with a large number of sports population in the system. Sensitivity and optimal design analysis show some interesting results. First, increasing interpersonal communication and mass communication can both increase the number of conscious non-sports population and sports population. For increasing the number of conscious non-sports population, the effect of mass communication is better than that of interpersonal communication. For increasing the number of sports population, the effect of interpersonal communication is better than that of mass communication. However, individual participation has the best effect on increasing the sports population. Second, increasing the daily fixed amount of new information will be more helpful for media information dissemination. Finally, the three control measures need to be implemented simultaneously for a period of time at first, and then health education and participation of sports people need to be implemented periodically in order to maximize the sports population.

Why can customer incivility be contagious in the service context? A resource scarcity perspective

Customer incivility is common in the hospitality industry. Assuming a resource scarcity perspective, this study investigates the interpersonal transmission of such incivility in the service context. We proposed that: (i) fellow customers’ incivility (i.e., as a reminder of resource competition) can trigger focal customers’ incivility; (ii) focal customers’ self-interest concerns (i.e., resource competition–induced selfishness) mediate the positive relationship between focal customers’ and fellow customers’ incivility (i.e., selfishness promotes special access to resources); and (iii) when attributing fellow customers’ incivility to an employee’s mistake, focal customers display greater self-interest concerns and express stronger incivility. Data from 302 customer–employee dyads generally supported our hypotheses. This study expands the understanding of bystander effects on customer incivility. Findings will also help service providers treat customer incivility more rationally and implement measures to help mitigate it.

Hospitalization among vaccines for SARS-CoV-2 breakthrough infection after dose sparing strategies in Libya: A cohort study.

SARS-CoV-2 infection is widely spread over people, from youth to the elderly. Vaccination against SARS-CoV-2 is an essential preventive measure to help end the SARS-CoV-2 pandemic. A multi-center retrospective cohort study was conducted on patients in Libya who had received single-dose licensed three different types of vaccines (Oxford/AstraZeneca, CoronaVac, or Sputnik-V) and were admitted to healthcare centers with SARS-CoV-2 infection from 30th April to 15th July 2021. In this study, the number of people infected with SARS-COV-2 and the mortality rate from daily reports issued by the National Centers for Disease Control of Libya (NCDC) were collected. Approximately 445000 single doses of the SARS-COV-2 vaccine were administered in Libya from April to July 2021. In corresponding, 39996 people were infected during this period. It has been found that among the people who did not receive any vaccine, the number of patients infected by SARS-COV-2 and admitted to the healthcare centers, and died was (N = 3176 patients (7.94%), and 266 (7.10%) respectively). Compared to 43 (0.10%) of those admitted to healthcare centers who had taken a single dose from one of the licensed vaccines, of which 8 patients (0.02%) died during this period. The documented 23 patients were those who admitted to healthcare centers and got vaccinated with the CoronaVac (Sinovac) vaccine. Fourteen patients received Oxford/AstraZeneca. Only 2 patients received the Sputnik V vaccine. Of the breakthrough infection cases reviewed, 8 patients died. No deaths due to breakthrough infection among Sputnik V vaccinated patients were reported. In conclusion, a single dose of the three different types of the vaccine has significantly reduced virus interpersonal transmission and also showed a decrease in the mortality rate until the tenth week in Libya. The present study demonstrates the extent of the remarkable success of the early rollout of the coronavirus national vaccination campaign.

Predictors of physical distance in the context of the COVID-19 pandemic | Fact-sheets collection from the Portuguese COVID-19 pandemic Task Force on Behavioral Sciences

The promotion of physical distancing is a highly effective way of preventing the interpersonal transmission of pathogenic agents, including SARS-CoV-2. However, the protection of physical health through physical distance should not promote social distancing, which is a relevant disrupter of human subjective and psychological well-being. Interpersonal bonds are essential for the promotion and protection of mental health and quality of life. It is, therefore, necessary to identify adequate criteria for the establishment and promotion of adequate, protective, and health-promoting physical distancing.

Intranasal SARS-CoV-2 Vaccines: Indispensable and Inevitable

Their extraordinary efficacy notwithstanding, the parenterally administered mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have proven incapable of preventing breakthrough infections in otherwise fully vaccinated subjects.1 Interpersonal transmission of SARS-CoV-2 through respiratory droplets and aerosols by fully vaccinated subjects has also proven resistant to vaccine-induced immunity.1 These relative shortcomings of the parenterally administered mRNA vaccines are hardly unanticipated because upper airway protection against SARS-CoV-2 replication and shedding requires local mucosal rather than systemic humoral immunity.

SARS-CoV-2 Vaccines: The Mucosal Immunity Imperative

SARS-CoV-2 Vaccines: The Mucosal Immunity Imperative

Numerical investigation of the effects of environmental conditions, droplet size, and social distancing on droplet transmission in a street canyon

This study investigated interpersonal droplet transmission between a healthy and an infected person in a two-dimensional (2D) street canyon using Computational Fluid Dynamics (CFD) simulation. The CFD simulation modeled four droplet sizes (Dp), two ambient wind speeds (Uref), three relative humidity (RH) levels, and four social distances (D) to estimate their effects on interpersonal droplet transmission. The results revealed that under weak ambient winds (Uref = 1.54 m/s), droplets had more upward movements and longer airborne time, but strong dispersions under high winds (Uref = 6.68 m/s). RH has trifling influence on the dispersion of small droplets (Dp = 10, 25 and 50 μm), but significantly modify the dispersion of large droplets (Dp = 100 μm), especially under low ambient winds. Small droplets travel longer distances in dry air (RH = 35%) and either land on the surrounding buildings' walls or become suspended in the air. In contrast, 45% of the large droplets are inhaled by pedestrians or become suspended in the dry air. But when evaporation is slow at RH = 95%, they would rapidly fall to the ground or land on the pedestrians’ lower bodies due to heavy mass. With farther apart social distancing, small droplets pose little infection risks, but that risk of infection increased for large droplets due to complex interactions with the ambient airflow and gravity. A 2 m social distance is recommended for pedestrians in deep urban street canyons with high winds, and 4 m if winds and RH are low.