AbstractResearch on how business model innovation (BMI) in international markets affects international performance continues to proliferate. However, existing research is sparse on primary predictors of this relationship. Drawing upon knowledge creation theory, this article investigates a serial mediation model that supports the role of the indirect effects of foreign knowledge acquisition (FKA) via international orientation (IO) and BMI on international performance. Utilizing time‐lagged survey data from multiple respondents in Ghana (N = 352), the results revealed that high levels of FKA enhance BMI via increased IO, and BMI ultimately improves international performance. Implications relating to theory and practice are discussed.